Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): a 12-month longitu... by Camila Amormino Corsini, Guilherme Rodrigues Fernandes Campos, Priscila Fernanda da Silva Martins, Priscilla Soares Filgueiras, Ana Esther de Souza Lima, Sarah Vieira Contin Gomes, Caroline De Almeida Leitao Curimbaba, Daniela Aparecida Lorencini, Eolo Morandi Junior, Victor Mattos da Silva, Maria Célia Cervi, Marcos de Carvalho Borges, Marcos de Carvalho Borges, Poliana Remundini de Lima, João Paulo Resende do Nascimento, Paulo Roberto Lopes Correa, Leda dos Reis Castilho, Jaquelline Germano de Oliveira, Olindo Assis Martins Filho, Maurício Lacerda Nogueira, Maurício Lacerda Nogueira, Maurício Lacerda Nogueira, Immunita team, Rafaella Fortini Queiroz e Grenfell, Rafaella Fortini Queiroz e Grenfell, Rafaella Fortini Queiroz e Grenfell, Ana Clara Almeida, Daniel Alvim Pena de Miranda, Isabela Camargos, Raquel Amorim, Érica Louback de Oliveira, Clara Raíssa do Prado Pêgo, Viviane Cristina Fernandes dos Santos

“…No significant differences in neutralization between BA.1 and BA.5 were observed post-vaccination, contrary to prior literature, suggesting uniform effectiveness against these subvariants.DiscussionThis study demonstrates that CoronaVac significantly enhances and sustains neutralizing antibody titers in children and adolescents for up to one year, including against immune-evading subvariants like BA.5. …”
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Quantitative characterization of types 1 and 2 macular neovascularization in neovascular age-related macular degeneration with intravitreal conbercept: an analysis utilizing optica... by Yan-Mei Shi, Xiao Xie, Wen-Qi Wang, Xiao-Meng Yuan, Zhi-Ping Zhang, Hong-Yan Wang, Jie Meng, Ze-Hao Kong, Xia Jing, Ting-Ting Liu

“…Moreover, in type 1 MNV, final best-corrected visual acuity (BCVA) using logMAR correlated positively with both pre- and post-treatment CMT, while in type 2 MNV, a significant positive correlation was found between the number of injections and final CMT. …”
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Dietary mixtures of Bacillus spp. modulates intestinal morphology, resistance to Vibrio parahaemolyticus, response of immune-antioxidant genes, and growth of Dicentrarchus labrax by El-Sayed Hemdan Eissa, Afaf N. Abdel Rahman, Ragaa A. Ahmed, Basma M. Hendam, Yasmin M. Abd El-Aziz, Hagar Sedeek Dighiesh, Moaheda E.H. Eissa, Ekemini Moses Okon, Norhan H. Ahmed

“…Moreover, the expression of growth [insulin-like growth factor 1 (1.41-, 1.91-, 2.15-, and 2.65-fold) and growth hormone (1.67-, 1.97-, 2.25-, and 2.72-fold)] and immuno-antioxidant associated genes [complement3 (1.42-, 1.95-, 2.33-, and 2.52-fold), interleukin-1 beta (1.30-, 1.76-, 2.43, and 2.82-fold), SOD (1.40-, 1.86-, 2.47-, and 2.64-fold), and GPx (1.22-, 1.75-, 2.55-, and 2.75-fold)] were up-regulated in MBs-fed groups (1–4 g/kg), respectively. Post-challenge with V. parahaemolyticus, the MBs3 and MBs4 groups had the highest survival rate (70.00 and 70.00 %), followed by the MBs2 group (60.00 %) and MBs1 group (50.00 %) compared to control (30.00 %). …”
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A new analytical model of Cultural Linguistics (2023) by Mohammad Hossein Keshavarz and Mahdi Noshadi. Cambridge Scholars. by Ali Dabbagh

“…</p> <p>In sum, considering the unique features of this unprecedented volume, it can be used as a good source of reading for different undergraduate and post-graduate courses such as Linguistics, Sociolinguistics, Cognitive Linguistics, Anthropology, and Cultural Studies. …”
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PREDICTIVE SIGNIFICANCE OF ANTI-HLA AUTOANTIBODIES IN HEART TRANSPLANT RECIPIENTS by O. P. Shevchenko, T. A. Khalilulin, G. A. Olefirenko, R. M. Kurabekova, N. V. Apanasenko, A. O. Shevchenko, B. L. Mironkov, I. M. Ilyinsky, A. G. Kupriyanova, A. J. Kormer

“…The presence of preformed anti-HLA antibodies in candidates for heart transplantation increase the risk of AMR and CAV post transplantation in 2,3 and 2,7 times, respectively.…”
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Safety and Immunogenicity of the Attenuated Yellow Fever Vaccine in Several Neotropical Primate Species by Nayara Ferreira de Paula, André Duarte Vieira, Daniel Oliveira dos Santos, Lucas dos Reis de Souza, Carlyle Mendes Coelho, Herlandes Penha Tinoco, Paula Cristina Senra Lima, Rafael Otávio Cançado Motta, Valéria do Socorro Pereira, Marcelo Pires Nogueira de Carvalho, Camilla Bayma Fernandes, Adriana de Souza Azevedo, Matheus Soares Arruda, Thais Alkifeles Costa, Betania Paiva Drumond, Fabiola de Oliveira Paes Leme, Marcos da Silva Freire, Tatiane Alves da Paixão, Ayisa Rodrigues Oliveira, Renato Lima Santos

“…In addition, an ethogram was performed to assess clinical changes and animal welfare. Results: At 4 days post-vaccination, RNAemia was detected in nine animals. …”
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Donor – recipient selection using epitope mismatches in kidney transplantation by A. V. Vatazin, A. B. Vatazin, V. A. Stepanov

“…With the number of EpMM in the range from 10 to 24 and from 25 to 43  the difference in survival rates was statistically significant, but only at the late stages of the post-transplant  period: log-rank test p = 0.0067, Breslow test p = 0.0982. …”
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Reconstitution of T cell‐mediated immunity by umbilical cord‐derived mesenchymal stem cells in ulcerative colitis by Xiaoying Luo, Jieping Deng, Xiaoke Jiang, Jun Mi, Yangqiu Bai, Huimin Zhang, Yalong Li, Min Liu, Conghui Cai, Pengju Li, Huanrong Huang, Yueping Xu, Yiwen Qin, Yang Mi, Hui Ding, Zhiyu Yang, Yue Wu, Zhenjuan Li, Ling Lan, Lida Zhang, Li Wang, Guobing Chen, Han Yue, Oscar Junhong Luo, Bingyong Zhang

“…The 26 enrolled patients were administered two UMSC doses intravenously. Pre‐ and post‐therapy colon biopsy specimens were analysed by single‐cell RNA sequencing (scRNA‐seq). …”
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Cognitive training gain transfer in cognitively healthy aging: per protocol results of the German AgeGain study by Florian U. Fischer, Florian U. Fischer, Bianca Kollmann, Bianca Kollmann, Dominik Wolf, Alexandra Sebastian, Alexandra Sebastian, Kristel Knaepen, David Riedel, Andreas Mierau, Andreas Mierau, Nicolas Ruffini, Nicolas Ruffini, Kristina Endres, Kristina Endres, Jennifer Winter, Heiko K. Strüder, Gerard N. Bischof, Gerard N. Bischof, Sofia Faraza, Sofia Faraza, Bernhard Baier, Harald Binder, Alexander Drzezga, Alexander Drzezga, Alexander Drzezga, Stefan Teipel, Stefan Teipel, Andreas Fellgiebel, Andreas Fellgiebel, Oliver Tüscher, Oliver Tüscher, Oliver Tüscher, Oliver Tüscher, Oliver Tüscher

“…Therefore, the present multicentric study used a cognitive training intervention to demonstrate training transfer and identify neurobiological modulators of successful transfer.MethodsIn total 235 subjects were enrolled in AgeGain; 180 underwent a broad 4-week cognitive training intervention at three study sites. Pre- and post-training neuropsychological testing was conducted and successful transferers were identified according to preregistered definitions. …”
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Tocilizumab-Based Treatment of Microvascular Inflammation in Kidney Transplant Recipients: A Retrospective Study by Johan Noble, Johan Noble, Johan Noble, Giorgia Comai, Giorgia Comai, Valeria Corredetti, Reda Laamech, Celine Dard, Thomas Jouve, Thomas Jouve, Diane Giovannini, Audrey Le Gouellec, Shivani Wadnerkar, Paolo Cravedi, Della Apuzzo, Della Apuzzo, Daniele Vetrano, Daniele Vetrano, Marco Busutti, Chiara Abenavoli, Chiara Abenavoli, Paolo Malvezzi, Lionel PE Rostaing, Lionel PE Rostaing, Gaetano Lamanna, Gaetano Lamanna

“…The eGFR trajectory significantly decreased after TCZ treatment (−1.2 ± 0.2 vs. 0.03 ± 0.2 mL/min/1.73 m2/month pre- vs. post-TCZ, respectively; p = 0.001). The percentage of patients with DSA decreased from 63.9% to 38.9% (p &lt; 0.001), and the average MFI decreased from 9,537 to 7,250 (p = 0.001). …”
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Loomeprotsessi semiootilisest uurimisest helilooja käsikirjade näitel. Arvo Pärdi „Sieben Magnificat-Antiphonen“ lähivaates / Composer Manuscripts and the Semiotic Study of the Cre... by Kristina Kõrver

“…From a textological standpoint, the article considers the full lifespan of a work, from the earliest notation of an idea to the final manuscript, including post-publication revisions and arrangements for new ensembles. …”
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Genetic Interplay Between Attention-Deficit/Hyperactivity Disorder and Pain Suggests Neurodevelopmental Pathways and Comorbidity Risk by Nicolas P. Ciochetti, Victor F. de Oliveira, Iago Junger-Santos, Cibele E. Bandeira, Maria E. Tavares, Eduardo S. Vitola, Luis A. Rohde, Gustavo Melo de Andrade, Bruna S. da Silva, Eugenio H. Grevet, Claiton H. Dotto Bau, Diego L. Rovaris

“…Methods: We utilized various post–genome-wide association study analyses on summary data from samples ranging between 225,534 and 766,345 individuals. …”
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Expanded analysis of vertebral endplate disruption and its impact on vertebral compression fracture risk by Khaled Dibs, Prasath Mageswaran, Raju Raval, Evan Thomas, Emile Gogineni, Jeff Pan, Brett Klamer, Ahmet Ayan, Eric Bourekas, Daniel Boulter, Nicholas Fetko, Eric Cochran, Vikram Chakravarthy, John McGregor, Esmerina Tili, Joshua Palmer, Natalie Peters, Russell Lonser, Ahmed Elguindy, Eugene Yap, Soheil Soghrati, William Marras, John Grecula, Arnab Chakravarti, James Elder, Dukagjin Blakaj

“…The 1-year cumulative incidence of VCF was evaluated by follow-up MRI and CT scans at 3-month intervals post-treatment. Based on multivariate analysis, a nomogram was created using four independent predictors: EP disruption, steroid use, SINS ≥ 7, and adverse histology. …”
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A proteogenomic analysis of cervical cancer reveals therapeutic and biological insights by Jing Yu, Xiuqi Gui, Yunhao Zou, Qian Liu, Zhicheng Yang, Jusheng An, Xuan Guo, Kaihua Wang, Jiaming Guo, Manni Huang, Shuhan Zhou, Jing Zuo, Yimin Chen, Lu Deng, Guangwen Yuan, Ning Li, Yan Song, Jia Jia, Jia Zeng, Yuxi Zhao, Xianming Liu, Xiaoxian Du, Yansheng Liu, Pei Wang, Bing Zhang, Li Ding, Ana I. Robles, Henry Rodriguez, Hu Zhou, Zhen Shao, Lingying Wu, Daming Gao

“…Proteomic stratification identifies three patient subgroups with distinct features in prognosis, genetic alterations, immune infiltration, and post-translational modification regulations. PRKCB is further identified as a potential radioresponse-related biomarker of CC patients. …”
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Machine learning-based prediction model for lung ischemia-reperfusion injury: insights from disulfidptosis-related genes by Yanpeng Zhang, Yanpeng Zhang, Yanpeng Zhang, Jingyang Sun, Jingyang Sun, Jingyang Sun, Yihan Lin, Yihan Lin, Yihan Lin, Rongxuan Jiang, Rongxuan Jiang, Rongxuan Jiang, Niuniu Dong, Niuniu Dong, Niuniu Dong, Huanhuan Dong, Huanhuan Dong, Huanhuan Dong, Peng Li, Peng Li, Peng Li, Jinteng Feng, Jinteng Feng, Jinteng Feng, Zijiang Zhu, Guangjian Zhang, Guangjian Zhang, Guangjian Zhang

“…The CIBERSORT method was used to assess the infiltration levels of immune cells in lung tissue samples post-transplant. Finally, cell line and animal experiments were carried out to validate the effectiveness and applicability of the model.ResultsA total of 14,592 hub differential-expressed genes were identified, showing significant changes in cold ischemia and reperfusion samples. …”
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Basic therapeutic approaches to the management of hematology/oncology patients with new coronavirus infection (COVID-19) by E. N. Misyurina, E. A. Baryakh, N. F. Frolova, O. N. Kotenko, Z. Yu. Mutovina, S. S. Andreev, T. N. Tolstykh, K. V. Yatskov, E. A. Karimova, A. B. Makeshova, O. A. Rukavitsyn, A. V. Misyurin, Yu. Yu. Polyakov, M. A. Mingalimov, T. S. Chudnova, D. E. Gagloeva, D. D. Ivanova, A. I. Koneva, O. L. Kochneva, E. N. Zotina, E. Yu. Grishina, L. T. Shimanovskaya, V. N. Yakimets, E. I. Zhelnova

“…Recently, antiviral drugs and monoclonal antibodies have become available for pre- or post-exposure prophylaxis, as well as for early treatment of COVID-19. …”
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DFO-loaded PDA nanoparticles facilitated 3D stem cell spheroids for diabetic wound repair by normalizing the pathological microenvironment by Tong Luo, Peijun Zhu, Shuai Li, Maolin Qin, Zeyu Fang, Fangfang Wu, Qian Wu, Suhong Lu, Yinhe Zhang, Yuli Chen, Junhua Zhou, Daqing Chen, Liangliang Yang, Hongyu Zhang

“…Despite the high therapeutic potential of 3D stem cell spheroids, owing to their structural and functional advantages, the complex microenvironment encountered post-transplantation significantly diminishes their survival and efficacy. …”
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Clinical Outcomes and Health Care Utilization in Patients with Advanced Chronic Kidney Disease not on Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada by Carol Wang, Yuguang Kang, Stephanie N. Dixon, Nivethika Jeyakumar, K. Scott Brimble, Amit X. Garg, Peter G. Blake, Therese A. Stukel, Matthew J. Oliver, Ahmed Al-Jaishi, Kristin K. Clemens, Longdi Fu, Jane Ip, Susan McKenzie, Louise Moist, Amber O. Molnar, Flory Muanda-Tsobo, Marian Reich, Pavel Roshanov, Samuel A. Silver, Ronald Wald, Matthew A. Weir, Kevin Yau, Ann Young, Kyla L. Naylor

“…Poisson generalized estimating equations were used to predict post-COVID-19 patient outcomes and health utilization based on pre-COVID trends, estimating relative changes between the observed and expected outcomes. …”
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Global Feature Focusing and Information Enhancement Network for Occluded Pedestrian Detection by ZHENG Kaikui, JI Kangyou, LI Jun, LI Qiming

“…Existing methods, including post-processing optimization, specific model based improvements, and body part feature based methods, have limitations such as inaccurate handling of heavily occluded positive samples, high computational complexity, and susceptible to background noise. …”
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Comparison of cerebrospinal fluid biomarkers in patients with severe COVID-19 neurological outcomes and Alzheimer’s disease by Fernanda G.Q. Barros-Aragão, Thaís L. Pinheiro, Talita P. Pinto, Bart Vanderborgh, Nathane B.S. Rezende, Guilherme B. de Freitas, Gabriel R. de Freitas, Fernando A. Bozza, Andrea S. Souza, Erika C. Rodrigues, Carlos O. Brandão, Paulo Mattos, Felipe K. Sudo, Fernanda F. Tovar-Moll, Fernanda G. De Felice

“…Considering that inflammation may persist post-COVID, our findings urge the assessment of possible AD-related biomarker changes in COVID-19 survivors with lingering symptoms.…”
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