Classification and identification of yeast strain A82-2 and its inhibitory effect on Rhizopus stolonifer by ZHOU Xiaohong, YAN Dong, LU Zhaoxin, LU Fengxia, SHEN Chang, BIE Xiaomei

“…Based on the above results, we concluded that P. anomala A82-2 significantly inhibited R. stolonifer, therefore it has an important application potential in biological control and post harvest preservation of fruit and vegetable.…”
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Histological and inflammatory effects of 26.5 GHz quasi-millimeter wave exposure on rat skin by Etsuko Ijima, Akiko Nagai, Kun Li, Takashi Hikage, Naomi Kamizawa, Emi Hidaka, Yukina Tsuruta, Tatsuya Ishitake, Hiroshi Masuda

“…Furthermore, serum levels of prostaglandin E2 (PGE2), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) were measured at each post-exposure time point.ResultsHistological analysis revealed burn-like tissue damage in the 500 W/m2 exposure group, characterized by subepidermal blister formation, epidermal thickening, and dermal edema, which increased in severity over time. …”
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Investigating the nutritional status, outcomes and needs of adolescents and young adults (AYA) following a cancer diagnosis: protocol for a mixed-methods study by Andrew Murnane, Erin Laing, Belinda Steer, Jeremy Lewin, Heather Gilbertson, Elizabeth Mount, Mary-Anne Silvers, Jenelle Loeliger, Jodie Bartle, Kristin Mellett, June Savva, Pasquale L. Fedele, Lisa M. Orme, Leanne Super, Karla Gough, Kate Thompson

“…Study assessments will be undertaken at four time-points (recruitment, and 2- 4- and 6-months post-recruitment) and will include screening for nutrition risk (PNST or MST); assessment of nutritional status (PG-SGA, mid-upper arm circumference); assessment of muscle strength (hand-grip strength); frequency of dietitian referral, nutrition support and symptoms; and assessment of health-related quality of life (AQoL-6D); (2) Qualitative study using focus groups with AYA to assess access to nutrition related care and preference for nutrition services; (3) Qualitative study, utilising focus groups with oncology healthcare professionals (OHP) to explore and assess current access to nutrition-related care for AYA following a cancer diagnosis along with OHP nutrition education needs, service delivery and research priority areas. …”
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In situ insights into antibody-mediated neutralization of a pre-fusion Junin virus glycoprotein complex by Lily J. Taylor, Michael R. Sawaya, Jonna B. Westover, Chenyi Wang, Frederick Jimenez, Aldo J. Muñoz, Julian Whitelegge, Brian B. Gowen, Gustavo F. Helguera, Roger Castells-Graells, Jose A. Rodriguez

“…The 3.8 Å resolution in situ structures of the antibody-neutralized, 3-fold symmetric JUNV GPC reveal its ectodomain architecture, signal peptide-bound transmembrane region, zinc-binding luminal domain, and post-translational modifications. JUNV-GPC sequence variants highlight the functional importance of the signal peptide transmembrane helix register for virus infection and attenuating Candid#1-associated variants. …”
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Comparative Survival Analysis of Anti‐Angiogenic Agent Plus Immunochemotherapy in NSCLC Patients After Frontline EGFR‐TKI Treatment: A Retrospective Cohort Study by Yi‐Tse Su, Shu‐Farn Tey, Chung‐Ta Lee, Chien‐Yu Lin, Jeng‐Shiuan Tsai, Chien‐Chung Lin, Chin‐Wei Kuo

“…Survival outcomes were assessed through progression‐free survival (PFS) and overall survival post‐TKI failure (OSpTKI). Propensity score was employed to match patients, with Kaplan–Meier curve and multivariable Cox regression analysis determining the survival benefits. …”
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Tourniquet use in total knee arthroplasty and the risk of infection: a meta‐analysis of randomised controlled trials by A. A. Magan, O. Dunseath, P. Armonis, A. Fontalis, B. Kayani, F. S. Haddad

“…However, tourniquet use has recently been linked with increased post‐operative pain, reduced range of motion, and slower functional recovery. …”
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Maximal and sub-maximal exercise tests alter PBMC microRNA expression: insights into sport- and sex-specific variations by Guy Shalmon, Guy Shalmon, Guy Shapira, Guy Shapira, Rawan Ibrahim, Ifat Israel-Elgali, Meitar Grad, Rani Shlayem, Ilan Youngster, Ilan Youngster, Mickey Scheinowitz, Mickey Scheinowitz, Noam Shomron, Noam Shomron

“…Participants underwent VO2max and time-to-exhaustion tests, with blood samples collected pre- and post-exercise to analyze PBMC microRNA levels.ResultsRunners exhibited a higher microRNA response than cyclists or controls, with significant sex-based differences. …”
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Fall risk perception toolkit based on “digital human” for community-dwelling older patients with stroke: development and validation by Jiang Nan, Yi Hou, Manyao Sun, Xueying Huang, Jing Gao, Xueqiong Zou, Zhongyi Chen, Yuyu Jiang

“…The usability test contained Post-Study System Usability Questionnaire (PSSUQ), Customer Effort Score (CES), Net Promoter Score (NPS), and user interviews. …”
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Vitamin A attenuates PFOS-induced neurotoxicity and alters early proximity patterns to conspecifics in zebrafish larvae by Peiyun Jiang, Jingyu Wang, Xiaoying Wang, Li Zou, Li Zou, Di Wu, Qu Xu, Yue Jiang, Mengmeng Yao, Mengmeng Yao, Qin Hong, Qin Hong, Xia Chi, Xia Chi

“…This study investigates vitamin A’s neuroprotective capacity against PFOS-induced toxicity, particularly focusing on social behavior deficits—a core phenotype of autism spectrum disorder (ASD).MethodsZebrafish larvae were exposed to 1 μM or 5 μM PFOS (with/without 5 nM vitamin A co-treatment) from 24–144 hours post-fertilization (hpf). Control groups received 0.01% DMSO (vehicle) or 5 nM vitamin A alone. …”
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Size-dependent interactions between calciprotein particles and vascular endothelium by Zeping Zhang, Xinyue Wang, Caihao Huang, Meixia Wang, Wei Cui, Liang Hao, Rui Yang, Hong-hui Wang, Xing Zhang

“…Two primary types of CPP1 were studied: small-sized CPP1 (S-CPP1, <50 nm) and larger CPP1 (L-CPP1, <100 nm), detected three and five weeks post-surgery, respectively. By adjusting the amounts of Ca2+, HPO42− and H2PO4− ions in Dulbecco's Modified Eagle Medium supplemented with 10 % (V/V) fetal bovine serum and 1 % (V/V) Pen-Strep solution, S-CPP1 (<50 nm) with an elliptical shape, L-CPP1 (50–100 nm), and secondary CPPs (CPP2, >100 nm) with a needle-like crystalline structure, resembling endogenous CPPs, were synthesized. …”
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Full-scale test and numerical study on seismic performance of bridge piers with 650 MPa grade steel bars by Yong Li, Dezhang Sun, Junwu Dai, Yuxuan Peng, Dali Fang, Tao Jiang, Hongyu Lei

“…Then, a four-segment piecewise model is developed through systematic parameterization of experimental skeleton curves, delineating sequential behavioral phases: elastic deformation, crack initiation, yielding plateau, and post-peak strength degradation. Numerical simulations in OpenSees successfully replicates the hysteretic behavior of HRB650E bridge piers. …”
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Sintilimab and anlotinib with gemcitabine plus cisplatin in advanced biliary tract cancer: SAGC a randomized phase 2 trial by Jingjing Li, Shurui Zhou, Xiaoqing Xu, Qinhong Zheng, Fabiao Zhang, Cong Luo, Da Li, Xing Sun, Zhe Han, Wei Wu, Junrong Yan, Yang Shao, Yuhua Zhang, Bingchen Wu, Qing Wei, Xinbao Wang, Yiwen Zhou, Weijing Sun, Qi Xu, Jieer Ying

“…At 13.4-month median follow-up, SAGC significantly improved median progression-free survival (8.5 vs. 6.3 months; HR 0.48, 95% CI 0.22–0.64, p = 0.005) and objective response rate (51.4% vs. 29.4%), with higher grade 3/4 adverse events (75.0% vs. 43.6%). Post hoc analysis showed enhanced efficacy with anlotinib 8 mg versus 10 mg (ORR 54.5% vs. 38.8%). …”
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STORCH Brazil: multicenter cohort study protocol to investigate neurodevelopmental paths and functioning in infants exposed to STORCH in Brazil by Daniele Almeida Soares-Marangoni, Amanda de Oliveira Arguelho, Ayrles Silva Gonçalves Barbosa Mendonça, Carine Carolina Wiesiolek, Carolina Daniel de Lima-Alvarez, Eloá Maria dos Chiquetti, Everton Falcão de Oliveira, Márcio José de Medeiros, Silvana Alves Pereira, Renata Hydee Hasue

“…A proposed total sample size of 296 infants will be included at 3 months (12–15 weeks post term). They will be equitably divided into: (a) an exposed group (n = 148), consisting of those diagnosed with any congenital STORCH infection or whose mothers experienced prenatal STORCH infection; (b) an unexposed group (n = 148). …”
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Is the Presence of a Depressive Disorder a Risk Factor for Worse Metabolic Outcomes Among Patients with Type 2 Diabetes Treated with GLP-1 Analogs? by Joana Nicolau, Pilar Sanchís, María Isabel Tamayo, Guadalupe Pérez-Bec, Guido Sfondrini, Mireia Grimalt, Lluís Masmiquel

“…However, patients with DD maintain higher post-treatment HbA1c levels, underscoring the need for integrated metabolic and psychiatric care in diabetes management.…”
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Association between antenatal glucocorticoid exposure and the activity of the stress system, cognition, and behavior in 8‐ to 9‐year‐old children: A prospective observational study... by Florian Rakers, Ekkehard Schleußner, Isabel Muth, Dirk Hoyer, Sven Rupprecht, Karin Schiecke, Tanja Groten, Michelle Dreiling, Valeska Kozik, Matthias Schwab, Heike Hoyer, Carolin Ligges

“…A monotonic dose–response relation between BM exposure and activity of the ANS and IQ was estimated in post‐hoc analyses. Conclusions Antenatal exposure to BM in the context of threatened preterm birth was not associated with changes in HPAA activity in childhood. …”
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Development and Validation of a Differentiating Infected from Vaccinated Animals (DIVA) Enzyme-Linked Immunosorbent Assay (ELISA) Strategy for Distinguishing Between Hendra-Infecte... by Leanne McNabb, Amy McMahon, Ezana Getachew Woube, Kalpana Agnihotri, Axel Colling, Christopher C. Broder, Indre Kucinskaite-Kodze, Rasa Petraityte-Burneikiene, Timothy R. Bowden, Kim Halpin

“…The validation of this assay strategy was performed using a positive cohort of 19 serum samples representing post-infection sera, a negative cohort of 1138 serum samples representing horse sera collected pre-vaccine release and a vaccination cohort of 502 serum samples from horses previously vaccinated with Equivac^® HeV vaccine. …”
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Effect of implementing care protocols on acute ischemic stroke outcomes: a systematic review by Karina Fonseca de Souza Leite, Mariana Gaspar Botelho Funari de Faria, Rubia Laine de Paula Andrade, Keila Diane Lima de Sousa, Samuel Ribeiro dos Santos, Kamila Santos Ferreira, Carlos Eduardo Menezes de Rezende, Octavio Marques Pontes Neto, Aline Aparecida Monroe

“…However, there is still a need to invest in reducing post-thrombolysis complications and mortality.…”
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Is Copper-61 the New Gallium-68? Automation and Preclinical Proof-of-Concept of ⁶¹Cu-Based Radiopharmaceuticals for Prostate Cancer Imaging by Diana Rodrigues, Alexandra I. Fonseca, Sérgio do Carmo, José Sereno, Ivanna Hrynchak, João N. Moreira, Célia Gomes, Antero Abrunhosa

“…Subsequent PET/MR imaging with [⁶¹Cu]Cu-NODAGA-PSMA-I&T showed tumor uptake lasting up to 4 h post-injection, predominant renal clearance, and no detectable accumulation in non-targeted organs. …”
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Plasma cytomegalovirus DNA load predicts outcomes in liver transplant recipients by Hao‐Chien Hung, Po‐Jung Hsu, Jin‐Chiao Lee, Yu‐Chao Wang, Chih‐Hsien Cheng, Tsung‐Han Wu, Ting‐Jung Wu, Hong‐Shiue Chou, Kun‐Ming Chan, Wei‐Chen Lee, Chen‐Fang Lee

“…We aimed to evaluate the efficacy of real‐time DNA quantitative polymerase chain reaction (qPCR) in the early detection of CMV and predicting post‐transplant outcomes. Materials and Methods This was a retrospective study that enrolled a total of 49 adult LT recipients between December 2016 and October 2019. …”
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One-year clinical outcomes of an observational study of static lung preservation at 10° centigrade and semi-elective lung transplantation by Christopher M. Bobba, Biplab Saha, Yuriy Stukov, Liam Kugler, Mohammad A. Aladaileh, Olusola Oduntan, William Weir, Jeffrey P. Jacobs, Cynthia Gries, Amir Emtiazjoo, Mindaugas Rackauskas, MD

“…Left lung ischemic time (performed second at our institution) was significantly longer in the SE group (722 minutes vs 318 minutes). Post-operative outcomes, including PGD at 72 hours, prolonged MV, ICU and hospital LOS, rejection, re-exploration, and re-admissions were not statistically different between the 2 groups. 1- year survival was 93% for SE patients, and 100% for controls. …”
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