Multi-omics analysis of bariatric surgery’s impact on type 2 diabetes and prediabetes by Balqees Almazrouei, Mira Mousa, Andre Barreiros, Nour Al Dain Marzouka, Michael Olbrich, Sanjay Ramachandran, Sreejisha P. Sreedharan, Sarah K. Azzam, Sarah El Hajj Chehadeh, John Rodriguez, Juan P. Pantoja, Javed Raza, Gabriel Diaz Del Gobbo, Mohammed Abdallah, Juan S. Barajas-Gamboa, Syed Salman Ashraf, Carlos Abril, Mohammad Al Bataineh, Habiba Al Safar

“…Eighteen microbial genera were found to differentiate between the pre- and post-surgery states. Our analysis revealed four microbial genera (Enterobacter, Enterococcus, Gemella, and Erysipelotrichaceae UCG-003) associated with two T2D SNPs (rs11830243 and rs6978118) and three CVD SNPs (rs9490306, 62207434, and rs34606058). …”
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Pre-procedural abnormal von Willebrand factor function predicts clinical outcomes after Transcatheter Aortic Valve Implantation: a prospective cohort study by Haitham Abu Khadija, Mohammad Alnees, Mohammad Alnees, Omar Ayyad, Gera Gandelman, Nizar Abu Hamdeh, Amir Haim, Yazan Hamdan, Ramon Cohen, Duha Najajra, Alena Kirzhner, Tal Schiller, Jacob George, Alex Blatt

“…In the arrhythmia model, AVWS appeared as a significant predictor of arrhythmias, with an OR of 4.480 [95% CI: (1.21, 16.49), p = 0.024].ConclusionsAssessing both DPC and von Willebrand factor function is crucial for predicting post-TAVI complications.…”
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Contrasting Patterns of Raccoon (Procyon lotor) Spatial Population Genomics Throughout a Rabies Management Area in Eastern North America by Matthew W. Hopken, Clara P. Mankowski, Christine Thurber, Antoinette J. Piaggio, Kathleen M. Nelson, Richard B. Chipman, Zaid Abdo, Tore Buchanan, Ariane Massé, Amy T. Gilbert

“…We discovered a potential phylogeographic split between central and southern samples from those in the northeast region, which correlates with post‐Pleistocene recolonization detected in a multitude of species from the region. …”
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MRI-based risk factors for intensive care unit admissions in acute neck infections by Jari-Pekka Vierula, Harri Merisaari, Jaakko Heikkinen, Tatu Happonen, Aapo Sirén, Jarno Velhonoja, Heikki Irjala, Tero Soukka, Kimmo Mattila, Mikko Nyman, Janne Nurminen, Jussi Hirvonen

“…Abscess diameters were measured on post-gadolinium T1-weighted Dixon MRI, and specific edema patterns, retropharyngeal (RPE) and mediastinal edema, were assessed on fat-suppressed T2-weighted Dixon MRI. …”
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Gut-lung axis, probiotics, and prebiotics: insights on dysbiosis, mechanism, and prevention of lung cancer by Deepika, Zayed D. Alsharari, Md Faruque Ahmad, Jagphool Singh, Mohini Yadav, Anita Kumari, Anil Kumar, Karl R. Matthews, Rotimi E. Aluko, António Raposo, Najla A. Albaridi, Boshra Mozaffar, Ariana Saraiva, Ariana Saraiva, Saurabh C. Saxena

“…Seeking new methods to maintain lung health and prevent lung diseases, including lung cancer, remains urgent, especially in the post-COVID era.…”
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Abnormal metabolic activation of CD8+ T cells correlates with poor prognosis in acute myeloid leukemia by Bixia Wang, Jianing Tang, Yang Zhou, Qianqian Huang, Xinya Jiang, Fangqing Zhang, Shuang Fan, Qi Zhang, Jingrui Zhou, Yu Wang, Xiao-Jun Huang, Huidong Guo

“…However, relapse remains a major challenge, with limited effective options for managing post-transplant recurrence. Tumor cells escape immune surveillance by establishing a complex, immunosuppressive tumor microenvironment (TME), which plays a central role in immune evasion and disease relapse. …”
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Right Ventricular Function Score by Echocardiography for Predicting Outcomes After Heart Transplantation by Wei Sun, Yuji Xie, Ye Zhu, Yun Yang, Xin Zhang, Nianguo Dong, Guohua Wang, Yuman Li, Jing Wang, Qing Lv, Mingxing Xie, Li Zhang

“…Methods A total of 357 consecutive patients post HT who underwent echocardiography at our single institution were retrospectively included. …”
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Mitochondria transplanted adipose-derived stem cells/decellularized adipose tissue hydrogel for adipose tissue regeneration by Jiezhang Tang, Yige Han, Pan Ren, Lirong Xu, Zhanjun Lei, Jiaqi Li, Yiwei Cui, Jie Zhang, Jinqing Li, Xueyong Li

“…Nevertheless, the therapeutic potential is constrained by the suboptimal functionality of ADSCs, due to the donor health status, long-term culture, and the post-transplantation environment in vivo. Mitochondria transplantation can enhance the proliferation, migration, differentiation, and pro-angiogenic ability of mesenchymal stem cells, thereby improving the tissue regeneration outcomes. …”
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Incidence and Factors Associated with Self-Reported Skin Symptoms of Allergic Reactions to COVID-19 Vaccines by Karnsinee Thanborisutkul, Prapasri Kulalert, Kanthida Methaset, Sira Nanthapisal, Tibet Chunthatikul, Nathamon Phangpanya, Phenpraphatson Charoenying, Worakamon Atsawutmangkru, Suphatsara Srijaroen, Patcharaporn Punyashthira, Orapan Poachanukoon

“…<b>Background</b>: Few reports exist regarding the incidence and factors associated with allergic reactions to COVID-19 vaccines during post-marketing surveillance, especially for inactivated whole virus or viral vector vaccines. …”
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Disuse-Induced Muscle Loss and Rehabilitation: The National Aeronautics and Space Administration Bed Rest Study by Jessica M. Scott, PhD, Meghan Downs, PhD, Roxanne Buxton, MS, Elizabeth Goetchius, MS, Brent Crowell, MS, Robert Ploutz-Snyder, PhD, Kyle J. Hackney, PhD, Jeffrey Ryder, PhD, Kirk English, PhD, Lori L. Ploutz-Snyder, PhD

“…Interventions:. The 11-day post-bed rest rehabilitation program consisted of low intensity exercise and progressed to increased aerobic exercise duration, plyometric exercises, and higher intensity resistance exercise. …”
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Association between educational attainment and blood pressure in older adults: a study of two Finnish generational cohorts born 20 years apart by Adriana Lääti, Oskari Somerpalo, Konsta Teppo, Jenni Vire, Matti Viitanen, Ville Langén

“…Associations between education and BP were assessed using first ANOVA and post-hoc Tukey tests and then multiple linear regression, adjusted for age, gender, smoking, and body mass index. …”
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Effectiveness of a reduced dose of ready-to-use therapeutic food in community-based management of severe acute malnutrition: A non-inferiority randomized controlled trial in the De... by Julien Ntaongo Alendi, Cécile Salpeteur, Steve Botomba, Alemayehu Argaw, Victor Nikièma, Jean-Baptiste Mayavanga, Benjamin Guesdon, Marie Petry, Uwimana Sebinwa, Sophie Bruneau, Aimée Mupuala Masaya, Florence Mbiya Muadi, Samuel Mampunza Ma Miezi, Marie-Claire Muyer

“…The present study was conducted to provide further evidence on the effectiveness of reduced RUTF dose in a context of high food insecurity and post conflict humanitarian crisis, and with routine health staff.…”
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Tuina promotes nerve myelin regeneration in SNI rats through Piezo1/YAP/TAZ pathway by Yue Xu, Na Rentuya, Tianyuan Yu, Jiawang Yan, Hongzheng Zhang, Yingqi Zhang, Hanyu Zhang, Jiawei Sun, Jiayue Liu

“…Conclusion The activation of Schwann cells (SCs) and the regeneration of injured nerve myelin post-Tuina intervention are associated with alterations in the Piezo1/YAP/TAZ signaling pathway within SCs, induced by the mechanical forces generated through Tuina.…”
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A Prospective Exploratory Study of Functional Immunity Assessed by Pretreatment Interferon Gamma Release Assay in Relation to Different Systemic Therapies in Patients With Advanced... by Hsu-Ching Huang, MD, Han-Jhih Chang, MS, Chi-Lu Chiang, MD, Hsin-Yi Huang, MS, Yung-Hung Luo, MD, Yuh-Min Chen, MD, Tsu-Hui Shiao, MD, Chao-Hua Chiu, MD

“…Peripheral blood samples were collected pre- and post-treatment for IGRA testing using the QuantiFERON-TB Gold In-Tube (QFT-GIT) kit. …”
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Effect of the Protein Composition of Whole Nutrition Food for Special Medical Purposes on in Vitro Digestion Properties and Cell Calcium Transport Promotion by Weirong GUAN, Gengjie CUI, Shulin ZHENG, Na DONG, Yiming DING, Shengkai FANG, Hongyan LI, Jing WANG

“…Furthermore, a Caco-2 monolayer cell model was established to explore the effects of three whole nutrient foods for special medical purposes on calcium transport both pre- and post-digestion. The results showed that when the digestion time was 240 min, the degrees of hydrolysis for non-hydrolyzed whey protein B1 and moderately hydrolyzed whey protein B2 were 50% and 45.5%, respectively, which were greater than that of non-hydrolyzed protein B0 (the degrees of hydrolysis was 36.5%), and the average peptide chain lengths for B1 and B2 were 5.06 and 4.52, respectively, both shorter than that of B0 (average peptide chain length of 5.45), suggesting that B1 and B2 exhibited greater in vitro digestibility. …”
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Feasibility and Pathologic Outcomes of Peripheral Lung Vascular Targeted Photodynamic Therapy in a Normal Porcine Lung ModelTake-home Points by Jason Beattie, Mario Ghosn, Kwanghee Kim, Raymond Parrish, Jie Chen, Stephen B. Solomon, Sebastien Monette, Christopher Cheleuitte-Nieves, Reza Bergemann, Mohit Chawla, Bryan C. Husta, Or Kalchiem-Dekel, Yaniv Cohen, Dina Preise, Zachary Sacks, Avigdor Scherz, Lonny Yarmus, Jonathan A. Coleman, Robert P. Lee

“…Posttreatment radiology and pathology support measurable ablation fields and expected post-VTP changes. Interpretation: Our preclinical evidence provides early rationale for the study of safety and feasibility of bronchoscopic VTP ablation of peripheral lung cancers in humans.…”
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Closed-loop versus open-loop “remind-to-move” treatment using wearables for hemiparetic upper extremity in patients after stroke: A proof-of-concept study by Kenneth N. K. Fong, Jasmine P. Y. Pak, Alissa H. L. Koo, Maggie M. K. Szeto, Natalie M. T. Wong, Keily K. Y. Yau, Sharon F. M. Toh, Vivian W. Lou, Hector W. H. Tsang, Gary K. K. Lau

“…Evaluations were conducted at pre-/post-intervention and follow-up after 4 weeks using upper extremity motor performance behavioral measures, actual arm use questionnaire, and the kinematic data obtained from the device. …”
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A Cost-Effectiveness Analysis of Mosunetuzumab vs Tisagenlecleucel for Treatment of Third- or Higher-Line (3L+) Relapsed or Refractory (R/R) Follicular Lymphoma (FL) in Italy by Luminari S, Pinto A, Puccini B, D’Arpino A, Omodeo Salè E, Bellone M, Pradelli L, Sabinot A

“…The PSM model tracks patient outcomes based on time-to-event data, including progression-free survival (PFS) and post-progression survival (PPS). A matching-adjusted indirect treatment comparison (MAIC) approach was used to account for differences in trial population characteristics on the relative efficacy of mosunetuzumab to tisagenlecleucel. …”
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Synthesis and physico-chemical properties of high-quality expanded graphite by Yu. V. Hrebelna, E. M. Demianenko, M. I. Terets, V. V. Lobanov, S. V. Zhuravskyi, O. M. Ignatenko, K. O. Ivanenko, Yu. I. Gornikov, M. T. Kartel, Yu. I. Sementsov

“…The magnitude of the mass loss of oxidized graphite according to various variants of chemical post-cleaning and the temperature range of such loss remain practically unchanged. …”
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Walking gait biomechanics in individuals with quadriceps tendon autograft anterior cruciate ligament reconstruction by Kate Pfile, Bennett Prosser, Harris Slone, Michelle McLeod, Chris Gregory, Jennifer Hunnicutt

“…We hypothesized hip and knee joint biomechanics will differ between the QT-ACLR and nonsurgical limbs during the stance phase of gait.MethodsWe recruited a convenience sample of 14 patients with unilateral QT-ACLR ∼11 months post-surgery from an orthopedic surgery clinic. Three-dimensional hip and knee kinematics and kinetics and vertical ground reaction force were assessed while participants walked at self-selected speeds. …”
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