The Effectiveness of Deep Learning in the Differential Diagnosis of Hemorrhagic Transformation and Contrast Accumulation After Endovascular Thrombectomy in Acute Ischemic Stroke Pa... by Mehmet Beyazal, Merve Solak, Murat Tören, Berkutay Asan, Esat Kaba, Fatma Beyazal Çeliker

“…The study included 556 images of 52 patients (21 female and 31 male) who underwent EVT due to AIS, with hyperdense areas observed in the NCCT examination within the first 24 h post-EVT. The evaluated images were labeled as ‘contrast accumulation’ and ‘hemorrhagic transformation’. …”
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Ectopic ULBP2 Is Associated with Decreased NKG2D Expression in CD8⁺ T Cells Under T Cell-Modulatory Conditions in a Murine Tumor Model by Yasuhiko Teruya, Kosuke Yamaguchi, Kohei Yamane, Naomi Miyake, Yuji Nakayama, Takafumi Nonaka, Hiroki Chikumi, Akira Yamasaki

“…Tumor growth was uniformly assessed on day 21 post-transplantation, and TIL analysis was performed in groups with evaluable residual tumors. …”
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Protective effect of exercise induced metabolite-3 in ischemia-reperfusion injury by Zijie CHENG, Xuejun WANG, Zimu WANG, Juying QIAN

“…ResultsPlasma levels of EIM-3 were elevated post-exercise. EIM-3 was characterized as a phospholipid small-molecule compound with a partition coefficient (logP) of 5.58 and a solubility (logS) of −7.6, indicating favorable lipophilicity and cell membrane permeability. …”
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Impact of Hemoglobin Glycation Index on Complications Following Orthopedic Surgery: A Retrospective Comparative Propensity Score‐Matched Study by Yuhua Xiao, Bochen Sun, Guoyu Yu, Long Chen, Fenqi Luo, Jie Xu, Jun Luo, Ting Xue, Yiyang Xu

“…ABSTRACT Objective Patients with impaired glucose metabolism have an increased incidence of post‐operative complications. The best marker for glycemic control prior to elective orthopedic surgery remains unclear. …”
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Smoking cessation treatment prior to psychotherapy for patients with diagnosed mental disorders: study protocol for a randomized controlled trial by Esra Teresa Sünkel, Marie Neubert, Alla Machulska, Tim Klucken

“…Attitudes toward online interventions will be measured once at baseline, while all other measures will be assessed before the intervention, post-treatment, and at 6-week and 6-month follow-up sessions. …”
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Comparative analysis of AQP7 expression and cryotolerance in X- and Y-chromosome bearing bovine sperm by Jieru Wang, Jieru Wang, Ruchun Li, Fei Huang, Peng Niu, Yanling Zheng, Dongfang Yuan, Yan Du, Congcong Li, Mingcai Yang, Jiajia Suo, Jiajia Suo, Qinghua Gao, Qinghua Gao

“…Immunofluorescence revealed AQP7 localization to the post-acrosomal region, midpiece, and principal piece of Y-sperm with higher fluorescence intensity, whereas AQP3 distribution was comparable between groups.DiscussionThese findings imply a potential role for AQP7 in augmenting Y-sperm cryotolerance, providing molecular insights into sex-specific cryopreservation effects on fertility outcomes. …”
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A severity‐based tumor‐superior mesenteric/portal vein interface grading criteria as a predictor of survival outcomes in pancreatic head ductal adenocarcinoma patients undergoing p... by Benson Kaluba, Naohisa Kuriyama, Motonori Nagata, Takahiro Ito, Aoi Hayasaki, Takehiro Fujii, Yasuhiro Murata, Akihiro Tanemura, Masashi Kishiwada, Shugo Mizuno

“…Methods Two hundred and twenty‐six post‐CRT patients were enrolled and 22 had no tumor‐SMV/PV contact, while the remaining 204 had. …”
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Progressive Remote Axonal Degeneration Following Spinal Cord Injury: A Histological and MRI Study by Gergely David, Alice Motovylyak, Felix Schlegel, Zsofia Kovacs, Christian Kündig, Angela R. Filous, Jan M. Schwab, Matthew D. Budde, Jan Klohs, Patrick Freund

“…First, rats subjected to a thoracic contusion SCI (T8) and sham-operated rats were sacrificed at 56 days post-injury (dpi), and SMI-32 immunohistochemistry was used to assess remote axonal degeneration at cervical segments C2–C5. …”
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Archives and Health program for dementia: A pilot study of a non-pharmacological creative arts-based intervention protocol by Sara Uboldi, Lorenza Iannacci, Vanda Menon, Alessandro Bortolotti, Giulia Candeloro, Alessandro Crociata, Valeria Pica, Angelo Romagnoli, Maria Tartari, Andrea Fabbo, Alessandra Marasco, Pier Luigi Sacco

“…Quantitative emotional well-being was assessed using the RADAR toolkit, while qualitative insights were derived from focus groups, interviews, and ethnographic observations Results: The ''My Memory Box'' intervention led to a significant decrease in negative affect (Mean pre = 8.73, Mean post = 7.00, p = 0.007) without altering positive affect. …”
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Development and evaluation of a 99mTc-labeled olaparib analog for PARP imaging by Wei Xu, Junjie Yan, Xinlin Zhong, Donghui Pan, Xinyu Wang, Yuping Xu, Lizhen Wang, Chongyang Chen, Min Yang

“…In vivo experiments, micro SPECT/CT imaging provided clear visualization of MDA-MB-453 tumors with significant tumor-to-background distinction, and accumulation of [99mTc][Tc-HYNIC/EDDA]-olaparib was quantified at 3.45 ± 0.17%ID/g at 1 h post intravenous injection. Conclusion These findings suggest that [99mTc][Tc-HYNIC/EDDA]-olaparib holds great promise as a novel radiotracer for PARP imaging.…”
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Evaluation of blood flow in arteritic anterior ischemic optic neuropathy using laser speckle flowgraphy: A case series by Chiaki Yamaguchi, Naoki Kiyota, Noriko Himori, Takahiro Oshima, Takayuki Takeshita, Kazuko Omodaka, Satoru Tsuda, Toru Nakazawa

“…Pre-treatment, all fellow eyes showed no impairment in BCVA or changes in the cpRNFLT. Post-treatment, two fellow eyes showed an increase in ONH-MV and ONH-MT parameters (72.8 ± 32.6 % and 82.2 ± 22.3 %, respectively), while all fellow eyes showed an increase in choroidal MBR (152.7 ± 126.1 %). …”
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Decades of discovery: unveiling emerging trends, pivotal research areas, and landmark publications in national tobacco research in India by Alok Singh, Akanksha Kashyap, Saurabh Varshney, Sudip Bhattacharya

“…Inclusion criteria were confined to Indian-affiliated institutions contributing to national and global discourse on tobacco research.ResultsTobacco research in India showed a consistent upward trend post-2003, with notable surges corresponding to key public health developments. …”
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Targeting the CD39/CD73 pathway: New insights into cardiac fibrosis and inflammation in female cardiac surgery patients by Eitezaz Mahmood, Mark Robitaille, Yifan Bu, Adnan Khan, Marie-France Poulin, Feroze Mahmood, Ruma Bose, Kamal R. Khabbaz, Simon C. Robson, Robina Matyal

“…Estrogen acts on the CD39/CD73 purine pathway, and loss of estrogen effects may contribute to the increased inflammation seen in post-menopausal women. We aimed to compare CD39/CD73 expression and downstream fibrosis, and inflammation in men and women undergoing cardiac surgery and then used an ovariectomy/high fat diet mouse model to approximate women who present for cardiac surgery to test therapeutics. …”
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Exploring the role of TIGIT in patients with Small Cell Lung Cancer as a novel predictor of prognosis and immunotherapy response by Li Liu, Peng Wu, Bingzhi Wang, Jiyan Dong, Chaoqi Zhang, Wenchao Liu, Jianming Ying

“…Immunohistochemistry (IHC) was used to verify TIGIT expression in post-surgical and advanced SCLC samples, focusing on expression characteristics, prognostic value, and treatment response. …”
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Assessment of frailty in geriatric patients admitted to oncology: a quality improvement project by Safiyyah Samad, Robert Brown

“…Only 2% (n=1) of these patients had a frailty score documented within 48 h of admission.123 patients were admitted to oncology between 8 January and 8 February 2025 (post-intervention). 30% (n=37) of these patients were aged 65 and over. 19% (n=7) of these patients had a frailty score documented within 48 h of admission. …”
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Expression of miRNA-27a in the serum of patients with non-ST elevation acute coronary syndrome who underwent percutaneous coronary intervention by A. S. Draganova, E. A. Polyakova, D. A. Kolodina, K. Yu. Mikheeva, O. D. Belyaeva, M. I. Zaraysky, O. A. Berkovich, Е. V. Shlyakhto

“…Genetic control of the development of CAD at the post-transcriptional level is carried out using step-wise and multicomponent regulation of gene expression with the participation of specific molecules called micro-ribonucleic acids (miRNAs). …”
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Long-Term Donor Chimerism Monitoring for Relapse Risk Assessment After Pediatric Allo-HSCT by Prażmo A, Skowera P, Zaucha-Prazmo A, Lejman M

“…Chimerism analysis is one of the tools applied in post-transplant monitoring, as an increasing fraction of recipient cells after HSCT has been linked to a higher risk of relapse.Study Design: In this retrospective, single-centre study we have analysed the data of patients treated with allo-HSCT for a range of hematological malignancies in the Department of Paediatric Haematology, Oncology and Transplantology, Medical University of Lublin, Poland, between years 2002– 2018.Results: For all 103 patients 3-years OS was 72.6 (95% CI: 64.3– 82.0) and 3-years EFS was 72.0 (95% CI: 63.5– 81.6). …”
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A community-based intervention to challenge attitudes towards intimate partner violence: results from a randomised community trial in rural South-West Nigeria by Olusegun Awolaran, Funmilola OlaOlorun

“…The 6-month community mobilisation intervention, focused on creating awareness and challenging attitudes supportive of IPV, was evaluated using two cross-sectional surveys (pre-and post-intervention), 12 in-depth interviews, and nine focus group discussions. …”
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Feasibility of scaling-up an evidence-based physical activity behaviour change intervention into routine ambulatory hospital care: a retrospective implementation evaluation using t... by Ashley R. Dunford, Stephen Begg, Michael Kingsley, Paul O’Halloran, Byron M. Perrin, Stephen Barrett

“…Results Reach: In total, 37 participants were recruited during the 6-month recruitment period; pre- and post-data were available for 33. Effectiveness: PA increased from a median of 460 MET-mins/week to 840 (p < 0.001). …”
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Evaluating the immunogenicity of a mouse partial hindlimb for composite allotransplantation by Jia Hui (Angela) Sun, Jia Hui (Angela) Sun, Samantha Ligi, Felor Biniazan, Siba Haykal, Siba Haykal

“…Samples were collected at post-operative days 7 (POD7) and 14 (POD14) for histological analysis (H&amp;E staining, immunohistochemistry for CD8, caspase-3, CD31, and TUNEL) to assess cell infiltration, inflammatory T cell presence, apoptosis, and vascularization. …”
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