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29281
Imbalance of bladder neurohomeostasis by Myosin 5a aggravates diabetic cystopathy
Published 2025-03-01“…Results Bladder strips from diabetic rats exhibit increased responsiveness to external stimuli, with urodynamic assessments showing a progressive decline in bladder function, culminating in overactivity by the fourth week post-STZ injection. Co-localization of Myosin 5a with neurotransmitter-related proteins was observed, and the knockdown of Myosin 5a in bladder neurons led to a significant reduction in ChAT and SP expression. …”
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29282
Impact of Dental Treatment under General Anaesthesia on Oral Health-related Quality of Life, Weight and Oral Hygiene Measures in Children: A Quasi-experimental Study
Published 2025-02-01“…Materials and Methods: The present pretest-post-test quasi-experimental study involving children aged 3-6 years scheduled for dental treatment under GA was conducted in the Department of Paediatric Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia, from September 2022 to December 2023. …”
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29283
Fine-tuning electroconvulsive therapy: A cognitive comparison of brief and ultra-brief pulse widths
Published 2025-07-01“…Cognitive functions were assessed using standardized tools, including the Hindi mental status examination and Battery for ECT-related cognitive deficits. Pre- and post-treatment evaluations were compared to determine changes in cognitive performance. …”
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29284
Multi-sized microelectrode array coupled with micro-electroporation for effective recording of intracellular action potential
Published 2025-05-01“…In this study, we investigated the influence of microelectrode size on intracellular AP parameters and recording metrics post-micro-electroporation through simulations and experiments. …”
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29285
From Field to Fermentation: Optimizing Peanut Vine Nutrients Through Advanced Harvest and Silage Practices
Published 2025-05-01“…Firstly, the impacts of three advanced harvest times (10 days, 5 days, 0 days) on the nutrient composition of peanut vine (PV) were investigated to determine the optimal harvesting time for peanut vine; secondly, the chemical composition and fermentation characteristics of silage produced by combining peanut vine with either wheat bran (PV-WB silage) or corn meal (PV-CM silage) with adding different inoculants (named as TTX, DBN, and JNK) were evaluated; finally, the post-ensilage microbial community was analyzed to assess the effects of inoculants and silage substrates on the bacterial and fungal communities, as well as their interactions. …”
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29286
Serum uric acid and coronary artery disease risk: a 10-year prospective cohort study in healthy adults
Published 2025-05-01“…Sex-stratified analysis revealed a transient association in women (crude HR = 2.13, 95% CI: 1.14–3.96), which dissipated post-adjustment, while no significant association was observed in men. …”
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29287
Advancing immunomodulation in organ transplantation: the therapeutic potential of self-assembled rapamycin nanoparticles in allograft rejection
Published 2025-06-01“…Abstract Background Transplant rejection remains a significant challenge, necessitating effective post-transplant interventions. Although rapamycin (RAPA) is a recognized immunosuppressant, its utility is limited by poor solubility and delivery efficiency. …”
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29288
The effect of Fordyce happiness training on marital satisfaction and mental health in women with premenstrual syndrome
Published 2023-01-01“…The mean scores of mental health in the experimental group compared to the control group in the pretest, post-test, and follow-up (43.95±4.38, 41.20±5.73, 40.25±5.88) had a decreasing trend (P<0.05) but the mean scores of marital satisfactions in the experimental group (81.90±7.18, 86.35±8.16, 86.80±7.96, respectively) increased (P<0.05). …”
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29289
A Pilot Study: Maternal Undernutrition Programs Energy Metabolism and Alters Metabolic Profile and Morphological Characteristics of Skeletal Muscle in Postnatal Beef Cattle
Published 2025-03-01“…These offspring showed enhanced efficiency in nutrient utilization during the post-weaning growth period. Comprehensive analyses of metabolites and transcripts revealed the accumulation of proteinogenic amino acid, asparagine, in NR offspring LM at 300 d, while the abundance of nicotinamide adenine dinucleotide (NADH) and succinate were reduced. …”
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29290
Far-ultraviolet light causes direct DNA damage in human lung cells and tissues
Published 2025-05-01“…Irradiated human lung cells demonstrated reduced viability in vitro, and increased lactate dehydrogenase release into the culture medium 48 h post-irradiation. Our findings reveal that even low doses of Far-UVC (206 nm, 222 nm) light can penetrate monolayers of human lung epithelial cells, causing direct DNA damage in the form of (6 -4) photoproducts and DNA double-strand breaks, ultimately leading to cell death.…”
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29291
Midterm Outcomes of Percutaneous Intramyocardial Septal Radiofrequency Ablation for Hypertrophic Cardiomyopathy: A Single‐Center, Observational Study
Published 2024-08-01“…The primary outcome was the reduction of left ventricular outflow tract gradient after 6 months or more post‐PIMSRA. Secondary outcomes were periprocedural major adverse clinical events. …”
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29292
High precision, high time-cadence measurements of the MgII index of solar activity by the GOES-R Extreme Ultraviolet Irradiance Sensor 2: EUVS-C initial flight performance
Published 2025-01-01“…These systematic effects can be mitigated with additional post-data processing.…”
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29293
Implementation of the Cognitive Daisy (COG-D) for improving care planning and delivery for residents with dementia in care homes: results of a feasibility randomised controlled tri...
Published 2025-05-01“…Secondary objectives were to explore signals of effects in candidate outcome measures for residents and staff, obtained at baseline and 6- and 9-month post-randomisation. A process evaluation explored barriers and facilitators to intervention implementation through care-plan audits (to explore recommendations in response to COG-D assessments), interviews and focus groups with staff, residents and relatives. …”
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29294
Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy
Published 2025-06-01“…Cardiomyocyte specific calpain inhibition by transgenic calpastatin overexpression prevented the post‐stimulus myocardial hypertrophic response.…”
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29295
Estimation and Forecasting of Nigeria’s Residential, Commercial, and Industrial Electricity Demands
Published 2025-01-01“…The obtained results were post processed using MS Excel. The results indicated that Nigeria’s potential electricity demand will be 69783.099, 80383.785 and 90984.472 GWh by 2030, 2040 and 2050, respectively. …”
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29296
A case of small cell neuroendocrine carcinoma of the ampulla of Vater
Published 2020-06-01“…Small cell-type NEC was finally diagnosed. Four months post pancreatoduodenectomy, multiple liver metastases developed, and systemic chemotherapy was administered. …”
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29297
Targeted limbic self-neuromodulation for alleviating central sensitization symptoms in fibromyalgia
Published 2025-05-01“…A clinical follow-up was performed 10–12 months post-intervention. Results NFT led to a significant immediate and long-term reduction in the SSS (F(2,40) = 7.32, p = 0.00, ηp2 = 0.27) and the Fibromyalgia Impact Questionnaire (FIQ) (F(2,40) = 9.85, p = 0.00, ηp2 = 0.33), alongside multidomain short- and long-term clinical benefits. …”
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29298
Accuracy and Reliability of Smartphone Versus Mirrorless Camera Images-Assisted Digital Shade Guides: An In Vitro Study
Published 2025-07-01“…Reliability was evaluated using intraclass correlation coefficients (ICC), and group differences were analyzed via one-way ANOVA and Bonferroni post hoc tests (α = 0.05). SC-DSG showed significantly lower ΔE<sub>00</sub> deviations than MC-DSG (<i>p</i> < 0.001), falling within acceptable clinical AT. …”
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29299
The application of PET/CT with 18F-FDG in the differential diagnosis of lung solitary lesions
Published 2022-09-01“…According to the results of the morphological conclusion, malignant neoplasm was not diagnosed in 11 (10.2 %) patients, while post-inflammatory changes were detected in 7 patients (SUVmax from 2.3 to 15.15), hamartoma was verified in 3 patients (SUVmax from 1.1 to 4.2) and anthracosis was detected in 1 patient.Results. …”
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29300
Acceptance and Commitment Therapy-based empowerment intervention for asthma management in parent-child dyads: A pilot randomised controlled trial
Published 2025-12-01“…Preliminary efficacy was evaluated through asthma control and parental stress (primary outcomes); children’s asthma self-management ability; parental symptoms of anxiety and depression; psychological flexibility; asthma knowledge; and family empowerment in asthma management (secondary outcomes), measured at baseline and immediately post-intervention. Results: We achieved 61.5 % recruitment, 71.4 % intervention completion rates, and low attrition (children 3.5 %, parents 10.7 %). …”
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