Focal Versus Combined Focal Plus Radial Extracorporeal Shockwave Therapy in Lateral Elbow Tendinopathy: A Retrospective Study by Caterina Delia, Gabriele Santilli, Vincenzo Colonna, Valerio Di Stasi, Eleonora Latini, Antonello Ciccarelli, Samanta Taurone, Antonio Franchitto, Flavia Santoboni, Donatella Trischitta, Sveva Maria Nusca, Mario Vetrano, Maria Chiara Vulpiani

“…Primary outcomes were assessed using the Visual Analog Scale (VAS) for pain and the Patient-Rated Tennis Elbow Evaluation (PRTEE) for pain and functional impairment at baseline (T0), 4 weeks (T1), 12 weeks (T2), and 24 weeks (T3) post-treatment. Secondary outcomes included grip strength and ultrasonographic measurements of common extensor tendon (CET) thickness and vascularization. …”
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My Back Exercise app: an automated exercise intervention supported by educational notifications, a sleep programme and diet advice to improve function in people with chronic non-sp... by Manuela L Ferreira, Kim L Bennell, Christopher J Gordon, Josielli Comachio, Paulo Ferreira, Rachel K Nelligan, Serigne N Lo, Paula Beckenkamp, Anelise Moreti Cabral Silveira, Carlos Mesa-Castrillon, Katharine Roberts, Emma K Ho, Rowena J Field

“…The primary outcome will be self-reported physical function measured by the Patient-Specific Functional Scale at 6 weeks post-randomisation. Data will be analysed using the Student’s t-test or the non-parametric Mann-Whitney U test.Ethics and dissemination This trial was approved by the Human Research Ethics Committee (HREC) of The University of Sydney (HREC Approval No. 2023/HE000772). …”
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Clinical and Behavioral Correlates of Blood Acylcarnitine Profiles in Children with Autism Spectrum Disorder: A Cross-Sectional Analysis by Adriana Prato, Martina Randazzo, Maria Anna Messina, Giovanni Puglisi, Laura Rosy Aleo, Fiorella Ciantia, Lara Cirnigliaro, Renata Rizzo, Rita Barone

“…There was a significant difference in the severity of autism symptoms (ADOS CSS) related to the repetitive and restricted behaviors domain (CSS RRB) among the different groups (χ²(2) = 6.26; <i>p</i> = 0.044). The post hoc Dunn’s test with Bonferroni correction showed that ADOS-CSS RRB was significantly higher in ASD group A compared to ASD group B (<i>p</i> = 0.013). …”
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Paleogeography and regional interpretation of facies in Tirgan Formation, west of Kopet-Dagh sedimentary basin, northeast of Iran by Atefeh Chenarani, Meysam Shafiee Ardestani, Mohamad Vahidinia

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Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials by Johanna M. Ospel, Scott Brown, Salome Bosshart, Alexander Stebner, Kazutaka Uchida, Andrew Demchuk, Jeffrey L. Saver, Philip White, Keith W. Muir, Diederik W. J. Dippel, Charles B. L. M. Majoie, Tudor G. Jovin, Bruce C. V. Campbell, Peter J. Mitchell, Serge Bracard, Francis Guillemin, Michael Hill, Mayank Goyal

“…Background We investigate whether the National Institutes of Health Stroke Scale (NIHSS) at 24 hours could serve as a primary outcome in acute ischemic stroke trials, and whether combining 90‐day modified Rankin Scale (mRS) and 24‐hour NIHSS in a hierarchical outcome could enhance detection of treatment effect, using endovascular treatment (EVT) as an exemplary study intervention. Methods This was a post hoc analysis of pooled data from 7 randomized EVT trials. …”
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Optimization of Rosa roxburghii Tratt pomace fermentation process and the effects of mono- and mixed culture fermentation on its chemical composition by Xinxin Yi, Xinxin Yi, Shuo Zhang, Shuo Zhang, Duo Meng, Duo Meng, Jian Zhang, Jian Zhang, Chencen Lai, Chencen Lai, Min Zhang, Min Zhang, Xiaodong Sun, Xiaodong Sun, Haoxiang Yu, Pengjiao Wang, Pengjiao Wang, Xiuli Gao, Xiuli Gao, Xiuli Gao

“…Total phenols, total flavonoids, total triterpenes, ellagic acid, and vitamin C levels were higher in the fermented group with different strains and in the optimized group with mixed bacteria post-fermentation compared to the uninoculated group. …”
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The Prostate cancer–Exercise and Metformin randomised controlled feasibility Trial (Pre-EMpT) in men following active surveillance, radical prostatectomy and radiotherapy by Luke A. Robles, Lucy McGeagh, Jonathan Aning, Amit Bahl, Amarnath Challapalli, Anthony Koupparis, Raj Persad, Edward Rowe, Constance Shiridzinomwa, Richard M. Martin, J. Athene Lane

“…Co-primary outcomes were rates of randomisation and adherence which was defined as men brisk walking ≥30 minutes on at least 5 days with 10,000 steps daily (measured over one week 6-months after randomisation) with ≥ 60% adherence to metformin between 3- and 6 months post-randomisation using returned pill count. Secondary outcomes included self-reported adverse events and physical activity, feasibility of wearing activity monitors and questionnaire completion. …”
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Increased dietary nutrient density did not restore growth performance in broiler chickens offered diets with high canola inclusion by Milan Kandel, Shemil P. Macelline, Robin R. Melwani, Mehdi Toghyani, Ruth N. Zadoks, Peter H. Selle, Sonia Y. Liu

“…Body weight gain (P < 0.001), feed intake (P < 0.001), FCR (P = 0.003), and body weight corrected FCR at 2.5 kg (P = 0.007) were influenced by the dietary treatment from 0 to 42 days post-hatch. Including high levels of canola product depressed feed intake by 7.5 % (4854 versus 4490 g/bird) and weight gain by 7.6 % (3301 versus 3049 g/bird); increased weight-corrected FCR from 1.485 to 1.538 g/g compared to control diets (T1). …”
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Gender-specific assessment of lipid profiles correlation with serum uric acid in non-dialysis chronic kidney disease patients: Prospective observational cross-sectional study by Yousuf Abdulkarim Waheed, Yousuf Abdulkarim Waheed, Huanhuan Yin, Jie Liu, Shifaa Almayahe, Maryam Bishdary, Karthick Kumaran Munisamy Selvam, Syed Muhammad Farrukh, Shulin Li, Shulin Li, Yanping Wang, Yanping Wang, Disheng Wang, Disheng Wang, Disheng Wang, Xinglei Zhou, Dong Sun, Dong Sun, Dong Sun

“…The age-stratified analysis indicated that LDL-c was higher in individuals aged ≥70 compared to younger groups (P&lt;0.002), while HDL-c was higher in the 20–29 age group; with (P&lt;0.031). Post-hoc univariate tests revealed significant between quartile differences for all lipid variables (all P ≤ 0.05).ConclusionIn CKD population, SUA levels were positively associated with LDL-c, TC, and TG, while inversely associated with HDL-c. …”
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Ecosystem services potential and soil conservation policies with emphasis on degraded pastures in Brazil by Adriana Monteiro da Costa, Maise Soares de Moura, Isadora Fonseca Navarro, Victor Cordeiro da Silva, Teresa Cristina Tarlé Pissarra, Carlos Alberto Valera, Luís Filipe Sanches Fernandes, Fernando Antonio Leal Pacheco

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Persistence and decay of neutralizing antibody responses elicited by SARS-CoV-2 infection and hybrid immunity in a Canadian cohort by Amy Nouanesengsy, Anthony Semesi, Kim Quach, Danton Ivanochko, Walter Byrne, Matthew Hwang, Maria-Rosa La Neve, Matilde Leon-Ponte, Alice Litosh, Nicole Wisener, Khosrow Adeli, Aaron Campigotto, Eyal Grunebaum, Allison McGeer, Theo J. Moraes, Lusia Sepiashvili, Julia Upton, Jean-Philippe Julien, Upton Allen

“…Additionally, we found an association between robust antibody responses and individuals with severe COVID-19 clinical symptoms during the first-month post-symptom onset. For individuals who achieved hybrid immunity, a robust increase in anti-S1 IgGs and neutralizing antibodies followed the first vaccination dose; however, there was a minimal increase in the anti-S1 IgGs and neutralizing antibody titers after administration of the second dose of the vaccine. …”
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Autologous HIV-specific T cell therapy targeting conserved epitopes is well-tolerated in six adults with HIV: an open-label, single-arm phase 1 study by Danielle K. Sohai, Michael D. Keller, Patrick J. Hanley, Fahmida Hoq, Divyesh Kukadiya, Anushree Datar, Emily Reynolds, Dennis C. Copertino, Christopher Lazarski, Chase D. McCann, Jay Tanna, Abeer Shibli, Haili Lang, Anqing Zhang, Pamela A. Chansky, Cecilia Motta, Tan T. Huynh, Bridget Dwyer, Andrew Wilson, Rebecca Lynch, Talia M. Mota, Winiffer D. Conce Alberto, Zabrina L. Brumme, Natalie N. Kinloch, Conrad Russell Y. Cruz, Lynsay MacLaren Ehui, Sarah Henn, R. Brad Jones, Catherine M. Bollard

“…Three participants show persistence of HIV-reactive, product-associated T cell clones for ≥40 weeks post infusions. HST-NEETs infusions are well-tolerated. …”
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START—the Swiss tele-assisted rehabilitation and training program to support transition from inpatient to outpatient care in the subacute phase after a stroke: feasibility, safety... by Szabina Gäumann, Carina Ziller, Carina Ziller, Nele Paulissen, Nele Paulissen, Frank Behrendt, Frank Behrendt, Zorica Suica, Zorica Suica, Björn Crüts, Luana Gammerschlag, Katrin Parmar, Katrin Parmar, Hans Ulrich Gerth, Hans Ulrich Gerth, Leo H. Bonati, Leo H. Bonati, Leo H. Bonati, Corina Schuster-Amft, Corina Schuster-Amft, Corina Schuster-Amft

“…Patients will continue for 12 weeks post-discharge. For the feasibility assessment, process-, training- and mHealth-related parameter will be evaluated, which include recruitment rate, process-evaluation, safety, adherence, drop-out rate, stability and maintenance of the system, usability, quality, satisfaction, user and program experience, and perceived change. …”
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Bridging Land and Sea: Geophysical insights into coastal karstic groundwater dynamics, freshwater plumes and saltwater intrusions in the urban regions of Antalya (Türkiye) by Jasper J.L. Hoffmann, Ercan Erkul, Simon Fischer, Irfan Yolcubal, Pritam Yogeshwar, Wolfgang Rabbel, Amir Haroon, Şerif Bariş, Ahmet Şener, Jens Schneider von Deimling, Ismail Kaplanvural, Bülent Tezkan, Elif Şen, Felix Gross, Ertan Pekşen, Elnur Gasimov, Aaron Micallef

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Characteristics and Outcome of Partial Liver Transplant among Pediatrics in a Referral Transplant Center in Iran from 2010 to 2020 by Pooya Vatankhah, Mohammad Bagher Khosravi, Mohammad Hossein Eghbal, Naeimehossadat Asmarian, Mohammad Ali Sahmeddini, Fatemeh Khalili, Samaneh Ghazanfar Tehran, Hamed Nikoupour, Alireza Shamsaeefar, Kourosh Kazemi, Sahar Sohrabi Nazari, Saman Nikeghbalian, Seyed Ali Malekhosseini

“…The primary diagnoses included cholestatic diseases (44.4%) and metabolic diseases (34.1%). Post-transplant rejection and mortality rates were 21.1% (119 patients) and 36.1% (203 patients), respectively. …”
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Psychosocial outcomes of risk-adapted prevention for prostate cancer predisposition: study protocol for a longitudinal observational mixed-methods study by Dagmar Wieczorek, Tanja Fehm, Gerald Antoch, Günther Carl, Peter Albers, Andre Karger, Ralf Schäfer, Ulrike Dinger, Maike K Klett, Jale Lakes, Guenter Niegisch, Matthias Boschheidgen, Bernadette Jäger, Silke Redler

“…Psychosocial outcomes will be collected at four time points in the CAG (T0: baseline; T1: after first visit; T2: after risk stratification consultation; T3: follow-up 6 months after T2) and at two time points in the COG (T0: baseline during inpatient stay; T1: post-inpatient stay). Recruitment started in 2023, and the recruitment target is n=225 participants (CAG) and n=118 participants (COG). …”
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In-vivo assessment of myocardial calcium uptake using manganese-enhanced cardiovascular magnetic resonance in aortic stenosis by Abhishek Dattani, Saadia Aslam, Gaurav S. Gulsin, Aseel Alfuhied, Trisha Singh, Shruti S. Joshi, Lucy E. Kershaw, David E. Newby, Gerry P. McCann, Anvesha Singh

“…Results: Twenty-eight controls and ten subjects with severe AS (age 72 [61-75] years, 8 male, 7 symptomatic, valve area 0.81 [0.74-1.0] cm2) were recruited, with seven returning for repeat scans post-AVR. AS patients had higher BMI and blood pressure, and a greater incidence of hyperlipidemia compared to controls. …”
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GLP-1 and GIP may play a role in long-term weight trajectories after gastric bypass by Sara Andrade, Sara Andrade, Carolina B. Lobato, Carolina B. Lobato, Carolina B. Lobato, Carolina B. Lobato, Mariana Machado, Mariana Machado, Bolette Hartmann, Jens J. Holst, Jens J. Holst, Rui F. Almeida, Mário Nora, Mariana P. Monteiro, Mariana P. Monteiro, Marta Guimarães, Marta Guimarães, Marta Guimarães, Sofia S. Pereira, Sofia S. Pereira

“…So, our aim was to evaluate the hormone profiles of patients with long-term optimal and suboptimal response after gastric bypass (RYGB).MethodsThis cross-sectional study included 43 individuals who underwent RYGB surgery over 10 years ago, divided into two groups: 23 participants with no T2D history but different WR trajectories (cohort 1), and 20 with prior T2D diagnosis and optimal WL (cohort 2), with post-RYGB T2D remission (n=10) or relapse (n=10). …”
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Longitudinal multi-omics analysis of convalescent individuals with respiratory sequelae 6–36 months after COVID-19 by Huqin Yang, Lujia Guan, Yi Xue, Xuyan Li, Leyi Gao, Zhijin Zhang, Haifan Zhang, Haomiao Ma, Fengjiao Liu, Xuan Huang, Zhaohui Tong, Jieqiong Li

“…Abstract Background Approximately 10–30% of individuals continue to experience symptoms classified as post-acute sequelae of coronavirus disease 2019 (COVID-19 (PASC)). …”
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Infarct core growth rate and 90-day outcomes in ischemic stroke: subgroup analysis based on onset-to-recanalization time by Sha Chen, Sha Chen, Guofang Chen, Changzhi Zhao, Enle Wang, Yewen Zhou, Manhua Ding, Yang Zhang, Yang Zhang

“…Clinical outcomes were evaluated using the modified Rankin Scale (mRS) at 90 days post-procedure. The least absolute shrinkage and selection operator (LASSO) regression was employed for data screening. …”
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