Indoor Soundscape Perception and Soundscape Appropriateness Assessment While Working at Home: A Comparative Study with Relaxing Activities by Jiaxin Li, Yong Huang, Rumei Han, Yuan Zhang, Jian Kang

“…As hybrid work arrangements become the norm post-pandemic, our findings highlight the urgency of reimagining residential acoustic design to accommodate both focused work and restorative relaxation within the same home.…”
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The role of PD-1/PD-L1 in overshooting osteoclastogenesis in periprosthetic joint infections by Yi Ren, Denise Jahn, Stefanie Donner, Clemens Gwinner, Weijie Du, Dimitrios L. Wagner, Serafeim Tsitsilonis, Carsten Perka, Georg Duda, Arne Kienzle

“…Abstract Periprosthetic joint infection (PJI) is a critical complication following arthroplasty, leading to increased prosthesis failure rates post-treatment. This study explores the role of PD-1/PD-L1 signaling in osteoclastogenesis associated with PJI. …”
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Study protocol for a randomized controlled trial evaluating the effectiveness of a mother-child intervention model of neurogenic tremor as an add-on to treatment for emotional diso... by Yanli Zhao, Jiahua Xu, Jie Zhang, Jiaqi Song, Ning Yang, Hongzhen Fan, Zhe Dong, Shuping Tan

“…The intervention arm combines eight weeks of standard pharmacotherapy with an eight-week TRE group therapy, assessing at baseline, post-8-week treatment, and three-month follow-up. …”
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Antibody-dependent enhancement of SARS-CoV-2, the impact of variants and vaccination by Swapna Thomas, Maria K. Smatti, Hebah Atef Mohammad AlKhatib, Yaman Tayyar, Muna Nizar, Hadeel T. Zedan, Allal Ouhtit, Asmaa A. Althani, Gheyath K. Nasrallah, Hadi M. Yassine

“…These findings highlight the need to investigate the mechanisms underlying ADE and its implications for vaccine design and post-infection immunity against respiratory viruses.…”
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Influence of puberty stage in immune-inflammatory parameters in well-trained adolescent soccer-players, following 8-weeks of pre-seasonal preparation training by Marios Hadjicharalambous, Eleanna Chalari, Nikolaos Zaras

“…Results: No significant treatment or interaction effects were found for erythrocyte sedimentation rate (ESR), platelets, total leucocyte count, immune inflammation markers (IIM), weekly rating of perceived exertion, body composition, sit-and-reach flexibility, or VO2max (P > 0.05). However, post-intervention neutrophil counts were increased, while lymphocyte counts decreased, and IIM levels rose in both groups (P < 0.05). …”
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The Effect of Combined Exercise and Curcumin Supplementation on TCF-1 and GSK3β Gene Expression in the Brains of Rats with Glioblastoma Multiforme by S Afshar Yousefi, Y Kazemzadeh, H Shirvani, S Mirzayan Shanjani

“…The collected data were analyzed using Shapiro-Wilk, Levin, one-way analysis of variance, Tukey's post hoc test and Pearson correlation. Results: The results of the present study indicated that the expression of TCF1 mRNA and GSK3β mRNA in the brain tumor tissue of rats showed a significant increase compared to the healthy control group (p<0.0001 for both). …”
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Understanding cross-talk–induced anode slippage in high-voltage mid-Ni NCM/graphite full cells by Seungjae Suk, Namgyu Yoo, Youngsu Lee, Jaesub Kwon, Heeju Ahn, Seungsu Yoo, Jaewoon Lee, Haneul Kim, Joongho Bae, Jongwoo Kim, Chiho Jo, Yong-Tae Kim, Kyu-Young Park

“…In this study, we reveal that anode slippage – induced by cross-talk-driven surface degradation – is the dominant factor in capacity fade during high-voltage (4.35 or 4.40 V) cycling of single-crystal mid-Ni layered oxide (SC-NCM)/graphite pouch full-cells. Electrochemical and post-mortem analyses show that, although high-voltage operation induces cathode surface degradation, including lattice oxygen loss and phase transitions, its direct impact on capacity loss is relatively minor compared to that of the anode. …”
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Development of an Affordable Silicone Phantom of The Kidney with 3D Printed Mould for Ultrasound Guided Percutaneous Nephrolithotomy Training in Indonesia [version 2; peer review:... by Ponco Birowo, Nur Rasyid, Jonathan Pratama Swannjo, Rananda Anggakara Hendarmo, Irfan Wahyudi, Kevin Yonathan, Gerhard Reinaldi Situmorang, Mahesh Ramanlal Desai, Widi Atmoko

“…Result The affordable PCNL model showed highly positive results among all participants (realistic anatomy 7.86/10, realistic visualization of calyx 8.19/10, realistic puncture 7.43/10, guidewire placement 8.19/10, realistic nephrostomy 7.57/10, stone visualization 7.76/10, feedback 7.52/10, post-training discussion 8.57/10). All of the participants recommended the affordable PCNL model phantom for ultrasound guided PCNL training in Indonesia. …”
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Single-blinded, randomised, parallel-group, controlled trial comparing the efficacy and cost-effectiveness of therapist- and self-guided internet-delivered behavioural activation v... by Matteo Bottai, David Mataix-Cols, Eva Serlachius, Fabian Lenhard, Sarah Vigerland, Johan Åhlén, Rebecca Andersson

“…Data will be collected at baseline, weekly for the initial 10 weeks, post-treatment and at 3 and 12-month follow-ups. …”
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Licochalcone D mitigates intracerebral hemorrhage-induced ferroptosis of neurons through COX2 inhibition by JiaLi Song, HuiYing Qiao, ShunLi Dong, JingMei Tang, Bai Li, Xi Zhou, Shan Lv, Rong Lv

“…ObjectiveThis study aims to assess LCD’s neuroprotective pharmacological effects against SBI post-ICH and identify its ferroptosis-inhibiting targets.MethodsAnimal models of ICH and cellular models of SBI were established. …”
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Inequities in PrEP annualized pill‐day coverage, United States, 2018–2022: a cross‐sectional pharmacoequity analysis by Patrick S. Sullivan, Eric Hall, Heather Bradley, Elizabeth S. Russell, Cory R. Woodyatt

“…To assess the potential impact of 2‐1‐1 PrEP dosing on median days of PrEP use, we compared 2018 and 2022 (pre‐ and post‐US Public Health Service guideline for 2‐1‐1 dosing). …”
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Nature-aligned approaches to form students’ system motivation by Marina V. Ulyanova

“…Only the system model of motivation, organized in such a way, forms life potential of personality in the process of education,  beginning with primary school and until post-graduate education, that is able to ensure good health and satisfy one’s vanity, without which he/she will not feel happy and assist sustainable development of the society on the whole. …”
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Pharmacological interventions for agitated behaviours in patients with traumatic brain injury: a systematic review by Sangeeta Mehta, David Williamson, Anne Julie Frenette, Lisa D Burry, Marc Perreault, Emmanuel Charbonney, Francois Lamontagne, Marie-Julie Potvin, Jean-Francois Giguère, Francis Bernard

“…In three studies evaluating safety outcomes, antipsychotics were associated with an increased duration of post-traumatic amnesia (PTA) in unadjusted analyses. …”
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Design of upper limb muscle strength assessment system based on surface electromyography signals and joint motion by Siqi Wang, Wei Lai, Yipeng Zhang, Junyu Yao, Xingyue Gou, Hui Ye, Jun Yi, Dong Cao

“…PurposeThis study aims to develop a assessment system for evaluating shoulder joint muscle strength in patients with varying degrees of upper limb injuries post-stroke, using surface electromyographic (sEMG) signals and joint motion data.MethodsThe assessment system includes modules for acquiring muscle electromyography (EMG) signals and joint motion data. …”
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Development and validation of an interpretable risk prediction model for perioperative ischemic stroke in noncardiac, nonvascular, and nonneurosurgical patients: a retrospective st... by Xuhui Cong, Xuli Zou, Ruilou Zhu, Yubao Li, Lu Liu, Jiaqiang Zhang

“…The Least Absolute Shrinkage and Selection Operator (LASSO) regression method was applied to select variables, followed by the development, validation, and performance evaluation of the predictive model using multivariate logistic regression analysis.ResultsThe prediction model, developed using nine variables including demographic information, medical history, and pre- and post-operative data, demonstrated strong discriminatory power in predicting perioperative stroke (AUC = 0.869; 95% CI, 0.827–0.910). …”
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Elucidating the dynamic tumor microenvironment through deep transcriptomic analysis and therapeutic implication of MRE11 expression patterns in hepatocellular carcinoma by Ruiqiu Chen, Chaohui Xiao, Zizheng Wang, Guineng Zeng, Shaoming Song, Gong Zhang, Lin Zhu, Penghui Yang, Rong Liu

“…Publicly available single-cell RNA sequencing (scRNA-seq) data and spatial transcriptomics were utilized to explore MRE11’s dynamic mechanisms in the tumor microenvironment (TME) of both primary and post-immunotherapy cases. We also screened for differentially expressed genes and constructed a robust HCC prognosis model using 101 machine-learning algorithms. …”
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Efficacy, Safety and Cost of Insecticide Treated Wall Lining, Insecticide Treated Bed Nets and Indoor Wall Wash with Lime for Visceral Leishmaniasis Vector Control in the Indian Su... by Dinesh Mondal, Murari Lal Das, Vijay Kumar, M Mamun Huda, Pradeep Das, Debashis Ghosh, Jyoti Priyanka, Greg Matlashewski, Axel Kroeger, Alexander Upfill-Brown, Rajib Chowdhury

“…Five households from each cluster were randomly selected for entomological measurements including sand fly density and mortality at one, three, nine and twelve months post intervention. Household interviews were conducted for socioeconomic information and intervention acceptability assessment. …”
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Effects of liraglutide on abdominal fat distribution and glucose metabolism in Chinese subjects with obesity by Mengyang Du, Jiang Yue, Yicheng Qi, Shengyun He, Xiaobing Lu, Minglan Yang, Lihua Wang, Qing Lu, Jing Ma

“…Fasting blood glucose (FBG) levels, 2 h post-load blood glucose (2hPBG) levels, and glycosylated hemoglobin (HbA1c) were remarkably improved after liraglutide monotherapy (all P < 0.001). …”
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Feasibility of evaluating AI-enabled digital symptom monitoring in metastatic patients with NSCLC receiving pembrolizumab therapy: A German single-arm observational pilot study by Melissa L. Santorelli, Oliver Schmalz, Mathias Hoiczyk, David Heigener, Clemens Schulte, Markus Knott, Petra Hoffknecht, Joonas Vainio, Thomas Burke, Josephine M. Norquist, Sabine Riehl, Alexander Hildner, Lisa Barthuber, Sabine Bohnet

“…Kaiku ® Health access required one login, while Lung AID EDC access required submission of ≥1 PRO questionnaire. Post hoc analyses explored access by site experience with Kaiku ® Health. …”
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Impact of a physical activity program on the health-related quality of life in pediatric cancer patients: a study protocol by Gustavo Galárraga, Gustavo Galárraga, Rebecca Wurtz, Marcos Di Stefano, Marcos Di Stefano, Libet Bosch, Erika Villanueva, Karen Unda, Yunqi Yu, Carmen Apolo, Camila Coloma, José Francisco López-Gil, José Francisco López-Gil

“…HRQoL surveys using a standardized instrument will be administered to all participants (those in the intervention group and those in the control group) at baseline, post intervention, and follow-up to assess changes over time. …”
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