Social alienation and influencing factors among caregivers of stroke patients in China: a cross-sectional study by Lang Xu, Lang Xu, Lang Xu, Shanshan Liu, Mao Luo, Min Li, Cong Wang, Cong Wang

“…IntroductionAs the primary bearers of post-stroke rehabilitation and long-term care, caregivers of stroke patients in China face a profound sense of social alienation that has not yet been fully recognized due to issues such as role-related limitations. …”
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A Resource-Efficient 3D U-Net for Hippocampus Segmentation Using CLAHE and SCE-3DWT Techniques by Faizaan Fazal Khan, Jun-Hyung Kim, Chun-Su Park, Ji-In Kim, Goo-Rak Kwon

“…Future work will focus on integrating post processing techniques, leveraging larger and more diverse datasets, and exploring higher-resolution volumetric data to further improve segmentation accuracy and clinical utility. …”
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A meta-analysis and systematic review of myocardial infarction-induced cardiomyocyte proliferation in adult mouse heart by Ya Liu, Lingyan Liu, Pengcheng Zhuang, Jiamin Zou, Xiaokang Chen, Hao Wu, Bingjun Lu, Wei Eric Wang

“…Results Evaluating cardiomyocyte proliferation by immunostaining of the cell cycle indicators on heart tissue, the meta-analysis showed that differences of Ki67+, PH3+, and BrdU/EdU+ cycling cardiomyocytes between MI and Sham groups were not statistically significant. In the post-MI heart, the percentages of PH3+, BrdU/EdU+, and AurkB+ cardiomyocytes were not significantly different between the infarct border zone and remote zone. …”
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Cardiac function unchanged following reanimation with normothermic regional perfusion in donation after circulatory deathCentral MessagePerspective by Nicholas W. Markin, MD, FASE, M. Megan Chacon, MD, Anthony W. Castleberry, MD, Lance Fristoe, CCP, Brian D. Lowes, MD, PhD, John Y. Um, MD, Marian Urban, MD, PhD

“…Objectives: To determine whether hearts reanimated with normothermic regional perfusion (NRP) have clinically detectable changes in function using echocardiography comparing the prearrest and post-NRP imaging. As heart transplantation from donation after circulatory death (DCD) continues to increase, preliminary results suggest outcomes comparable with donation after brain death. …”
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The Safety and Efficacy of Glibenclamide in Managing Cerebral Edema After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis by Majd M. AlBarakat, Rana B. Altawalbeh, Khaled Mohamed Hamam, Ahmed A. Lashin, Ahmed Wadaa-Allah, Ayah J. Alkrarha, Mohamed Abuelazm, James Robert Brašić

“…Primary outcomes included scores on the modified Rankin Scale (mRS) at discharge and the Subarachnoid Hemorrhage Early Brain Edema Score (SEBES) at ten days post-intervention. Secondary outcomes included adverse events, and safety and efficacy endpoints. …”
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Indications for extracorporeal membrane oxygenation in older adult patients with accidental hypothermia and hemodynamic instability by Shuhei Takauji, Mineji Hayakawa, Ryo Yamamoto

“…Methods This study was a post-hoc analysis of the ICE-CRASH study (2019–2022), a prospective, multicenter, observational study throughout Japan. …”
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Power Indices Through Rotational Inertial Devices for Lower Extremity Profiling and Injury Risk Stratification in Professional Soccer Players: A Cross-Sectional Study by Álvaro Murillo-Ortiz, Javier Raya-González, Moisés Falces-Prieto, Samuel López-Mariscal, Francisco Javier Iglesias-García, Luis Manuel Martínez-Aranda

“…Therefore, this study aimed to establish limb-specific normative values for flywheel-derived power indices in professional soccer players, while accounting for limb performance or ability, to explore the relationships between power indices across variables and to compare the power outcomes related to these indices between injured and non-injured players within four months post-assessment. <b>Methods</b>: Twenty-two male professional soccer players (age: 26.6 ± 4.6 years; competitive level: Belgian second division) were recruited from a single elite-tier club to participate in this cross-sectional diagnostic study. …”
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Carrion Increases Landscape‐Scale Scavenger Activity and Interactions by Patrick B. Finnerty, Niraj Y. Meisuria, Luke J. Baker, Rhys J. Cairncross, Emma Spencer, Mathew S. Crowther, Thomas M. Newsome

“…Overlap in activity times between the focal species on roads also increased post‐carcass deployment—especially during the winter month; however, peak activity times remained slightly offset. …”
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p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation by Ran Brosh, Reut Shalgi, Atar Liran, Gilad Landan, Katya Korotayev, Giang Huong Nguyen, Espen Enerly, Hilde Johnsen, Yosef Buganim, Hilla Solomon, Ido Goldstein, Shalom Madar, Naomi Goldfinger, Anne‐Lise Børresen‐Dale, Doron Ginsberg, Curtis C Harris, Yitzhak Pilpel, Moshe Oren, Varda Rotter

“…Thus, miRNAs and transcriptional regulators appear to cooperate in the framework of a multi‐gene transcriptional and post‐transcriptional feed‐forward loop. Finally, we show that, similarly to p53 inactivation, overexpression of representative miRNAs promotes proliferation and delays senescence, manifesting the detrimental phenotypic consequence of perturbations in this circuit. …”
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How do compression and flexion-compression injuries destabilize the spine? A novel in vitro protocol for analyzing three-dimensional biomechanical instability by Ann-Kathrin Greiner-Perth, Hans-Joachim Wilke, Christian Liebsch

“…Flexion-compression trauma (n = 6) was achieved by additional flexural loading of 10 Nm. Pre- and post-traumatic pure moment testing with 5 Nm was performed in flexion/extension, lateral bending, and axial rotation using optical motion tracking to determine range of motion (ROM), neutral zone (NZ), coupled rotations, and coupled translations. …”
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Dissolução de cimentos endodônticos resinosos por solventes orgânicos em diferentes intervalos de tempo by Anielle Pinheiro Schönhofen, Letícia Vieira Koch, Bruna Lucian Petry, Fabiana Soares Grecca, Patrícia Maria Poli Kopper, Augusto Bodanezi

“…Os dados foram analisados estatisticamente com ANOVA de duas vias, Bonferroni post hoc e teste de Pearson (α=0,05). Resultados: Endosolv R® foi significativamente mais eficiente na dissolução do Sealer26® do que a água destilada (grupo controle), óleo de laranjas e hipoclorito de sódio 2,5%. …”
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Cardiomyocyte proliferation and heart regeneration in adult Xenopus tropicalis evidenced by a transgenic reporter line by Xiao-Lin Lin, Jin-Hua Lin, Yan Cao, Han Zhang, Si-Yi He, Hai-Yan Wu, Ze-Bing Ye, Li Zheng, Xu-Feng Qi

“…In addition, the reporter line confirmed that apex resection injury greatly increased the proliferation of mlc2 + cardiomyocytes at 3-30 days post-resection (dpr), thereby regenerating the lost cardiac muscle by 30 dpr in adult Xenopus tropicalis. …”
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Evaluating the concordance between BICLA and SRI4 in patients with systemic lupus erythematosus from the placebo arms of the EXPLORER and ATHOS trials by Maria Dall’Era, Edward M Vital, Anca D Askanase, Jorge A Ross Terres, Justine Maller, Oliver Meier, Armando Turchetta, Huiyan (Ashley) Mao

“…We examined the concordance and the reasons for discordance in BICLA/SRI4 responses in participants with SLE receiving placebo and standard of care (SOC) in two randomised controlled trials.Methods This post-hoc analysis included data from the placebo arm (participants treated with SOC) of the EXPLORER (n=87; NCT00137969) and ATHOS (n=80; NCT02908100) trials. …”
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METODOLOGINIAI INFORMACIJOS VISUOMENĖS STUDIJŲ PROFILIAI: VYNAS JAUNAS, VYNMAIŠIAI SENI? by Marius Povilas Povilas Šaulauskas

“…It is argued that, taken as a whole, even the most radical information society theories, insisting on the post-modern "Age of Information", pour old wine (i.e. traditional assembly of methodological instrumentation, devised to tackle with explicitly modern societal change) into new wineskins (i.e. new previously unseen societal morphology ex definition requiring equally unique conceptual apparatus). …”
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Impact of Coastal Beach Reclamation on Seasonal Greenhouse Gas Emissions: A Study of Diversified Saline–Alkaline Land Use Patterns by Jiayi Xie, Ye Yuan, Xiaoqing Wang, Rui Zhang, Rui Zhong, Jiahao Zhai, Yumeng Lu, Jiawei Tao, Lijie Pu, Sihua Huang

“…This study demonstrates that GHG emissions from reclaimed wetlands can be effectively regulated through science-based land management, calling for prioritized attention to post-development practices rather than blanket restrictions on coastal exploitation.…”
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“It beats the hell out of going to a hospital”: service user experiences of telemedicine-based symptom-triggered alcohol withdrawal management by Nikki Bozinoff, Divya Prasad, Ke Bin Xiao, Anthony Ngoy, Bernard Le Foll, Anna Gordezky, Christian S. Hendershot, Sandra LaFleur, Lena C. Quilty, Victor M. Tang, Tara Marie Watson, Matthew E. Sloan

“…Six themes were identified: benefits of being in the home environment, technological tensions, intervention-specific feedback, personal motivations for participation, post-program achievements and changes and navigating the ‘system’. …”
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Comparative Evaluation of the Effect of Fiber Reinforcement on the Cuspal Deflection in Class II Mesio-occluso-distal Cavities Restored with Resin Composite: An <i>In Vitro</i> Stu... by Sandhya K Punia, Rahul Agarwal, Yogender Kumar, Deepak Sharma, Deepesh Mehta, Priyesh Patel

“…The cuspal deflection or the BPW was measured after 6- and 12-hours post-restoration. The obtained data were statistically analyzed using paired sample <i>t</i>-test using SPSS software V.21. …”
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Safety assessment of deutetrabenazine: real-world adverse event analysis from the FAERS database by Yanping Shu, Yuanhe Wang, Jiaoying Liu, Lingyan Hu, Sichao Tong, Gang Wu, Xianlin Zhu

“…BackgroundDeutetrabenazine is a widely used drug for the treatment of tardive dyskinesia (TD), and post-marketing testing is important. There is a lack of real-world, large-sample safety studies of deutetrabenazine. …”
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<i>ZmHPAT2</i> Regulates Maize Growth and Development and Mycorrhizal Symbiosis by Kailing Xie, Guoqing Wang, Ying Ni, Minghui Shi, Lixue Sun, Beijiu Cheng, Xiaoyu Li

“…Emerging evidence has shown that HPAT orthologs regulate plant development and symbiotic interactions through post-translational modification of <i>CLV1</i>/LRR Extracellular (CLE) peptides. …”
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Malignant Otitis Externa and Atypical Skull Base Osteomyelitis by Aarthi Gopal, Sophia Amalanathan, Srivalli Chilakamarri, Kumaran Ramesh Colbert, Satish Kumar C

“…Results: Among the 11 patients, 4 were from the pre-COVID period and the remaining 7 were from the post-COVID period. 10 patients had malignant otitis externa or lateral SBO and 1 had atypical/Central skull base osteomyelitis.  …”
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