Development of a lung perfusion automated quantitative model based on dual-energy CT pulmonary angiography in patients with chronic pulmonary thromboembolism by Linfeng Xi, Jianping Wang, Anqi Liu, Yifei Ni, Jie Du, Qiang Huang, Yishan Li, Jing Wen, Hongyi Wang, Shuai Zhang, Yunxia Zhang, Zhu Zhang, Dingyi Wang, Wanmu Xie, Qian Gao, Yong Cheng, Zhenguo Zhai, Min Liu

“…PerAIDE effectively differentiated CTEPH from CTEPD (AUC = 0.809, 95% CI: 0.745–0.863). At the 3-month post-BPA, a significant reduction in perfusion defects was observed (0.36 vs. 0.33, p < 0.01). …”
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Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females by Nan Zhang, Meng Yu, Qianru Zhao, Bing Feng, Yue Deng, Jonathan C. Bean, Qingzhuo Liu, Benjamin P. Eappen, Yang He, Kristine M. Conde, Hailan Liu, Yongjie Yang, Longlong Tu, Mengjie Wang, Yongxiang Li, Na Yin, Hesong Liu, Junying Han, Darah Ave Threat, Nathan Xu, Taylor Smiley, Pingwen Xu, Lulu Chen, Tianshu Zeng, Yanlin He, Chunmei Wang

“…Female mice with RE (>4 weeks post-weaning) displayed lower body temperature and a lower thermal preferred temperature, and lost preference for warm environments (30 °C) but preserved avoidance of cold environments (15 °C). …”
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Indo-Pacific Role in Iran’s East Look Strategy by Mohammad Reza Mohammadi

“…Based on the hypothesis that this engagement is affected by the challenges imposed by Western sanctions against Iran, and given the special position that the Indo-Pacific strategic area has in the post-Cold War geopolitical equations, Iran’s diplomatic apparatus has strong incentives to be present in the Indo-Pacific within the framework of the East Look strategy, which is expected to play a significant role in the future. …”
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Nanoscale piezoelectric patches preserve electrical integrity of infarcted hearts by Luís M. Monteiro, Pedro J. Gouveia, Francisco Vasques-Nóvoa, Susana Rosa, Ifigeneia Bardi, Rita N. Gomes, Simão Correia-Santos, Leonardo Ricotti, Lorenzo Vannozzi, Daniele Guarnera, Liliana Costa, André M. Leite-Moreira, Pedro Mendes-Ferreira, Adelino F. Leite-Moreira, Filippo Perbellini, Cesare M. Terracciano, Perpétua Pinto-do-Ó, Lino Ferreira, Diana S. Nascimento

“…Overall, the results presented here endorse Piezo patches as a promising therapeutic strategy to improve post-myocardial infarction structural and electrical remodeling.…”
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Cannabis legalization and cannabis use disorder in United States Veterans Health Administration patients with and without psychiatric disorders, 2005–2022: a repeated cross-section... by Deborah S. Hasin, Carol Malte, Melanie M. Wall, Daniel Alschuler, Tracy L. Simpson, Mark Olfson, Ofir Livne, Zachary L. Mannes, David S. Fink, Katherine M. Keyes, Magdalena Cerdá, Charles C. Maynard, Salomeh Keyhani, Silvia S. Martins, Scott Sherman, Andrew J. Saxon

“…Results were similar for MCL-only and MCL/RCL effects among disorder-specific groups (depression, post-traumatic stress disorder [PTSD], anxiety or bipolar disorders) and for MCL/RCL effects among patients with psychotic-spectrum disorders. …”
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Response‐adapted zanubrutinib and tislelizumab as a potential strategy to enhance CD19 CAR T‐cell therapy in relapsed/refractory large B‐cell lymphoma: A retrospective observationa... by Rong Shen, Wei‐Guo Cao, Li Wang, Ling‐Shuang Sheng, Yi‐Lun Zhang, Wen Wu, Peng‐Peng Xu, Shu Cheng, Meng‐Ke Liu, Yan Dong, Yue Wang, Xiang‐Qin Weng, Xu‐Feng Jiang, Qi Song, Hong‐Mei Yi, Lei Li, Sheng Chen, Zi‐Xun Yan, Wei‐Li Zhao

“…Patients were treated with zanubrutinib daily from leukapheresis to day 28 post‐infusion; those achieving complete response continued zanubrutinib monotherapy for 3 months, while partial responders received combined zanubrutinib for 3 months and tislelizumab for up to 2 years. …”
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Treatment With Avacopan in ANCA–Associated Vasculitis With Kidney Involvement by Duvuru Geetha, Frank B. Cortazar, Annette Bruchfeld, Andreas Kronbichler, Alexandre Karras, Georges N. Nakhoul, Peter A. Merkel, Sarah Bray, Alana M. Bozeman, David R.W. Jayne, C. Au Peh, A. Chakera, B. Cooper, J. Kurtkoti, D. Langguth, V. Levidiotis, G. Luxton, P. Mount, D. Mudge, E. Noble, R. Phoon, D. Ranganathan, A. Ritchie, J. Ryan, M. Suranyi, A. Kronbichler, A. Rosenkranz, K. Lhotta, N. Demoulin, C. Bovy, R. Hellemans, J. Hougardy, B. Sprangers, K. Wissing, C. Pagnoux, S. Barbour, S. Brachemi, S. Cournoyer, L. Girard, L. Laurin, P. Liang, D. Philibert, M. Walsh, C. Rigothier, J. Augusto, A. Belot, D. Chauveau, D. Cornec, N. Jourde-Chiche, M. Ficheux, P. Zaoui. Paris, A. Karras, A. Klein, F. Maurier, R. Mesbah, O. Moranne, A. Neel, T. Quemeneur, D. Saadoun, B. Terrier, P. Zaoui, M. Schaier, U. Benck, R. Bergner, M. Busch, J. Floege, F. Grundmann, H. Haller, M. Haubitz, B. Hellmich, J. Henes, B. Hohenstein, C. Hugo, C. Iking-Konert, F. Arndt, T. Kubacki, I. Kotter, P. Lamprecht, T. Lindner, J. Halbritter, H. Mehling, U. Schönermarck, N. Venhoff, V. Vielhauer, O. Witzke, I. Szombati, G. Szucs, G. Garibotto, F. Alberici, E. Brunetta, L. Dagna, S. De Vita, G. Emmi, A. Gabrielli, L. Manenti, F. Pieruzzi, D. Roccatello, C. Salvarani, H. Dobashi, T. Atsumi, S. Fujimoto, N. Hagino, A. Ihata, S. Kaname, Y. Kaneko, A. Katagiri, M. Katayama, Y. Kirino, K. Kitagawa, A. Komatsuda, H. Kono, T. Kurasawa, R. Matsumura, T. Mimura, A. Morinobu, Y. Murakawa, T. Naniwa, T. Nanki, N. Ogawa, H. Oshima, K. Sada, E. Sugiyama, T. Takeuchi, H. Taki, N. Tamura, T. Tsukamoto, K. Yamagata, M. Yamamura, P. van Daele, J. de Zoysa, A. Rutgers, Y. Teng, R. Walker, I. Chua, M. Collins, K. Rabindranath, J. de Zoysa, M. Svensson, B. Grevbo, S. Kalstad, M. Little, M. Clarkson, E. Molloy, I. Agraz Pamplona, J. Anton, V. Barrio Lucia, S. Ciggaran, M. Cinta Cid, M. Diaz Encarnacion, X. Fulladosa Oliveras, M. Jose Soler, H. Marco Rusinol, M. Praga, L. Quintana Porras, A. Segarra, A. Bruchfeld, M. Segelmark, I. Soveri, E. Thomaidi, K. Westman, T. Neumann, M. Burnier, T. Daikeler, J. Dudler, T. Hauser, H. Seeger, B. Vogt, D. Jayne, J. Burton, R. Al Jayyousi, T. Amin, J. Andrews, L. Baines, P. Brogan, B. Dasgupta, T. Doulton, O. Flossmann, S. Griffin, J. Harper, L. Harper, D. Kidder, R. Klocke, P. Lanyon, R. Luqmani, J. McLaren, D. Makanjuola, L. McCann, A. Nandagudi, S. Selvan, E. O'Riordan, M. Patel, R. Patel, C. Pusey, R. Rajakariar, J. Robson, M. Robson, A. Salama, L. Smyth, J. Sznajd, J. Taylor, P. Merkel, A. Sreih, E. Belilos, A. Bomback, J. Carlin, Y. Chang Chen Lin, V. Derebail, S. Dragoi, A. Dua, L. Forbess, D. Geetha, P. Gipson, R. Gohh, G.T. Greenwood, S. Hugenberg, R. Jimenez, M. Kaskas, T. Kermani, A. Kivitz, C. Koening, C. Langford, G. Marder, A. Mohamed, P. Monach, N. Neyra, G. Niemer, J. Niles, R. Obi, C. Owens, D. Parks, A. Podoll, B. Rovin, R. Sam, W. Shergy, A. Silva, U. Specks, R. Spiera, J. Springer, C. Striebich, A. Swarup, S. Thakar, A. Tiliakos, Y. Tsai, D. Waguespack, M. Chester Wasko

“…Introduction: Kidney disease impacts long-term outcomes of patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). This post hoc analysis evaluated the effect of avacopan in a subgroup of patients with GPA or MPA and kidney involvement at baseline from the ADVOCATE trial. …”
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Permafrost–wildfire interactions: active layer thickness estimates for paired burned and unburned sites in northern high latitudes by A. C. Talucci, M. M. Loranty, J. E. Holloway, B. M. Rogers, H. D. Alexander, N. Baillargeon, J. L. Baltzer, L. T. Berner, A. Breen, L. Brodt, B. Buma, B. Buma, J. Dean, C. J. F. Delcourt, L. R. Diaz, C. M. Dieleman, T. A. Douglas, G. V. Frost, B. V. Gaglioti, R. E. Hewitt, T. Hollingsworth, T. Hollingsworth, M. T. Jorgenson, M. J. Lara, R. A. Loehman, M. C. Mack, K. L. Manies, C. Minions, S. M. Natali, J. A. O'Donnell, D. Olefeldt, A. K. Paulson, A. V. Rocha, L. B. Saperstein, T. A. Shestakova, T. A. Shestakova, T. A. Shestakova, S. Sistla, O. Sizov, A. Soromotin, M. R. Turetsky, S. Veraverbeke, M. A. Walvoord

“…Simultaneously, wildfire activity across northern boreal forest and Arctic/subarctic tundra regions impacts permafrost stability through the combustion of insulating organic matter, vegetation, and post-fire changes in albedo. Efforts to synthesis the impacts of wildfire on permafrost are limited and are typically reliant on antecedent pre-fire conditions. …”
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Multiple Symptoms Study 3 – An extended-role general practitioner clinic for patients with persistent physical symptoms: a Randomised Controlled Trial by Christopher Burton, Cara Mooney, Laura Sutton, David White, Jeremy Dawson, Kate Fryer, Monica Greco, Michelle Horspool, Aileen Neilson, Gillian Rowlands, Tom Sanders, Ruth Thomas, Steve Thomas, Cindy Cooper, Jonathan Woodward, Emily Turton, Waquas Waheed, Pavi Kumar, Katie Ridsdale, Ellen Mallender, Vincent Deary

“…Outcome: The primary outcome measure was the PHQ-15 at 52 weeks post randomisation. Randomisation: Participants were randomised 1 : 1 using a centralised web-based system, stratified by study centre with random permuted blocks of varying sizes. …”
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BioImpedance Spectroscopy to maintain Renal Output: the BISTRO randomised controlled trial by Simon J Davies, David Coyle, Elizabeth Lindley, David Keane, John Belcher, Fergus Caskey, Indranil Dasgupta, Andrew Davenport, Ken Farrington, Sandip Mitra, Paula Ormandy, Martin Wilkie, Jamie MacDonald, Mandana Zanganeh, Lazaros Andronis, Ivonne Solis-Trapala, Julius Sim

“…The intervention was associated with £382 (95% confidence interval −£3319 to £2556) lower average cost per patient (price year 2020) and 0.043 (95% confidence interval −0.019 to −0.105) more quality-adjusted life-years and no harm compared to control. A post hoc 5-year analysis found better survival with more residual kidney function at enrolment and at any time over the next 2 years. …”
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Identification of Agricultural Events, Businesses and Landscapes in Chaharmahal and Bakhtiari Province by Golrokh Amiri Dowrhooni, Neda Torabi Farsani, Majid Farhadi Uonaki, Mehdi Karami Dehkordi

“…Below, the researchers mentioned a number of suitable research topics to make agricultural tourism more prominent in the province: Studying the making and managing the agricultural tourism brand in the province in order to promote agricultural tourism activities and products Evaluation of tourists' motivation to participate in agricultural tours and events in the province Preparation of agricultural tourism atlas of Chaharmahal and Bakhtiari province Preparation of agricultural tourism map of Chaharmahal and Bakhtiari province Identification of suitable strategies for the development of agricultural tourism in Chaharmahal and Bakhtiari province The role of virtual reality in visualizing destinations and post-experience behavioral intentions aligns with the developed findings. …”
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EIF4A3 Promotes Muscle Atrophy and Aging by Inhibiting the FAK Pathway Through NEDD9 mRNA Destabilization by Qian Li, Xiaohang Yin, Wensi Wan, Yi Zhou, Siqi Wang, Yuwei Yan, Jingying Chen, Xinyi Ren, Junli Gao, Yuying Chen, Yanan Zhang, Caiyue Cui, Emeli Chatterjee, Guoping Li, Ming Wu, Yan Zhang, Dongchao Lu, Tingting Yang, Yongjun Zheng, Jin Li

“…The exon junction complex (EJC), a protein complex assembly that binds to RNA, facilitates post‐transcriptional regulation by participating in mRNA splicing, mRNA export, translation and nonsense‐mediated mRNA decay. …”
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The kynurenine pathway as a potential link between ethanol-induced behavioral alterations and neuroinflammation by Leticia Gil de Biedma-Elduayen, Leticia Gil de Biedma-Elduayen, Leticia Gil de Biedma-Elduayen, Leticia Gil de Biedma-Elduayen, Pablo Giménez-Gómez, Pablo Giménez-Gómez, Pablo Giménez-Gómez, Pablo Giménez-Gómez, Pablo Giménez-Gómez, Nuria Morales-Puerto, Nuria Morales-Puerto, Nuria Morales-Puerto, Nuria Morales-Puerto, Rebeca Vidal, Rebeca Vidal, Rebeca Vidal, Rebeca Vidal, Álvaro Del Río-García, Álvaro Del Río-García, Álvaro Del Río-García, Álvaro Del Río-García, Carlos Núñez-de la Calle, Carlos Núñez-de la Calle, Carlos Núñez-de la Calle, Carlos Núñez-de la Calle, Lluna Careaga, Lluna Careaga, Lluna Careaga, Lluna Careaga, María Dolores Gutiérrez-López, María Dolores Gutiérrez-López, María Dolores Gutiérrez-López, María Dolores Gutiérrez-López, Esther O’Shea, Esther O’Shea, Esther O’Shea, Esther O’Shea, María Isabel Colado, María Isabel Colado, María Isabel Colado, María Isabel Colado

“…Here, we investigate the effect of EtOH dependence and withdrawal on behavioral and cognitive parameters, the nucleus accumbens (NAc) transcriptome, and KYN, TRP and serotonin (5-HT) levels and KYN/TRP and 5-HT/TRP ratios in mice.MethodsAdult male mice were subjected the Chronic Intermittent ethanol (CIE) paradigm, a model for dependence and withdrawal. Twenty-four hours post-EtOH exposure, we analyzed behavioral and cognitive parameters, sequenced the NAc transcriptome, and measured KYN, TRP and 5-HT levels as well as KYN/TRP and 5-HT/TRP ratios in plasma, limbic forebrain, cortex and cerebellum using HPLC.ResultsThe CIE model induced anxiety-like behavior and memory impairment. …”
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The Impact of Conservative Accounting on the Speed of Leverage Adjustment in Response to Stock Price Crash Risk by Abdullah Khaled Azeez, Akbar Zavari Rezaei, Mehdi Heidari

“…Materials & MethodsThis study employed both experimental and statistical methods to test the hypotheses. By utilizing post-event observations, the study minimized the potential for variable manipulation. …”
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Dose-escalation studies of mesenchymal stromal cell therapy for decompensated liver cirrhosis: phase Ia/Ib results and immune modulation insights by Lei Shi, Ziying Zhang, Song Mei, Zerui Wang, Zhe Xu, Weiqi Yao, Limin Liu, Mengqi Yuan, Yuefei Pan, Kaidi Zhu, Kai Liu, Fanglin Meng, Jiao Sun, Wenying Liu, Xiaohui Xie, Tengyun Dong, Lei Huang, Fanping Meng, Jun-Liang Fu, Yuanyuan Li, Chao Zhang, Xing Fan, Ming Shi, Yu Zhang, Yonggang Li, Wei-Fen Xie, Peng Zhang, Fu-Sheng Wang

“…These effects were sustained for up to seven days post-treatment but diminished by Day 14. Preliminary clinical signals included improvements in Child–Pugh scores, Model for End-Stage Liver Disease scores, liver function markers, and quality-of-life metrics, particularly in the higher-dose and multiple-dose groups. …”
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Comprehensive profiling of the catalytic conformations of human Guanylate kinase by Lei Wang, Zihuan Li, Yumi Xuan, Jingkun Qin, Shuju Li, Fumei Zhong, Yuexiao Song, Kanglong Yang, Mengqi Lv, Fudong Li, Zhang Jiahai, Yueyin Pan, Shouhong Guang, Yuzheng Zhao, Yunyu Shi, Xing Liu, Yingying Du, Jia Gao, Ke Ruan

“…Three key complexes, pre-reaction state (GMP/ATPγS), transition state (AlF4 - mimic), and post-reaction state (GDP/ADP), collectively delineate the reversible catalytic pathway. …”
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Long-term effectiveness, adherence and safety of twice-yearly paliperidone-palmitate long acting-injectable in patients with schizophrenia in Europe: 2-year mirror-image data from... by Sofía Manchado Perero, Ana Rodríguez Lorente, Alba García-Pérez, Guillermo Isidro García, Guillermo Isidro García, Luis Alberto Forcen-Muñoz, Santiago Ovejero García, Rocío Sáez Povedano, Ana Luisa González-Galdámez, Laura Mata Iturralde, Mariluz Ramirez Bonilla, Mariluz Ramirez Bonilla, Paloma Fuentes-Pérez, Claudia Ovejas-Catalán, Paula Suárez-Pinilla, Paula Suárez-Pinilla, Blanca Fernández Abascal, Blanca Fernández Abascal, Miguel Omaña Colmenares, María Pilar Campos-Navarro, Enrique Baca-García, Ana Lara Fernández, Sergio Benavente-López, Alberto Raya Platero, Miguel Barberán Navalón, Sergio Sánchez-Alonso, Javier Vázquez-Bourgon, Javier Vázquez-Bourgon, Javier Vázquez-Bourgon, Sofia Pappa, Sofia Pappa, Juan Antonio García-Carmona, Juan Antonio García-Carmona, Juan Antonio García-Carmona

“…In this 2-year mirror-image study we compare the number of hospital admissions 1 year pre- and post-PP6M initiation as well as the CGI scores at baseline and the point of each PP6M administration. …”
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INFECÇÃO BACTERIANA HOSPITALAR EM PACIENTES SUBMETIDOS A TRANSPLANTE HEPÁTICO EM 2008 by Maria Ozilene Rodrigues Batista, Maria Cristina Leite Araújo Borges, Ocilia Maria Costa Carvalho, Ana Maria Maia Rodrigues, Jaqueline Gomes de Souza Santos

“…MORENO, R & BERENGUER, M. Post-liver transplantation medical complications. …”
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Exploring the psychological and physiological outcomes of recreational pole dancing: a feasibility study by Ben Jackson, Cyril J Donnelly, Jacqueline A Alderson, James A Dimmock, Joanna Nicholas

“…., two 60-minute classes a week for eight weeks) and a post-program testing session resulting in an 89.5% retention rate. …”
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全基因组关联分析标准化流程的构建与扩展应用(Development and Extended Applications of Standardized Processes for Genome-Wide Association Studies) by 许喆1，2，石延枫1，2，张杰1，2，姜明慧1，2，刘阳1，2，李昊1，2，3，廖晓凌4，程丝1，2，3(XU Zhe1,2, SHI Yanfeng1,2, ZHANG Jie1,2, JIANG Minghui1,2, LIU Yang1,2, LI Hao1,2,3, LIAO Xiaoling4, CHENG Si1,2,3)

“…After quality control, 9632 and 7265 samples were included in the GWAS of baseline TG levels and 3-month post-stroke mortality phenotypes, respectively. The GWAS results showed that the trends of Manhattan plots obtained from different software were similar. …”
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