Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae by Ai Guo, Dianbao Zuo, Li Shi, Ming Guo, Jinquan Li, Caili Li, Puqing Wang, Xiaodong Sun, Ming Sang

“…The bacterial concentration markedly decreased at 2 h post-treatment, reaching its biological nadir by 6 h. …”
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Facing your fears in schools: using the ADIS/ASA to characterize anxiety and intervention outcomes in students with autism or suspected autism by Judy Reaven, Judy Reaven, Kelly T. Cosgrove, Kelly T. Cosgrove, Ainsley Losh, Ainsley Losh, Sarah Nickles, Sarah Nickles, Connor M. Kerns, Katherine Pickard, Audrey Blakeley-Smith, Audrey Blakeley-Smith, Lisa Hayutin, Lisa Hayutin, Allison T. Meyer, Allison T. Meyer, Caitlin Middleton, Caitlin Middleton, Nuri M. Reyes, Nuri M. Reyes, Richard E. Boles, Richard E. Boles

“…Caregivers completed the ADIS/ASA at baseline and post-intervention. The ADIS/ASA was administered by clinicians rigorously trained to reliability and masked to condition.ResultsStudents had both DSM-5 and distinct anxiety diagnoses at Time 1. …”
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Transcriptomic insights into the interplay between polyketide biosynthesis and other secondary metabolite biosynthetic clusters and biological pathways in entomopathogen Beauveria... by Wachiraporn Toopaang, Wachiraporn Toopaang, Wachiraporn Toopaang, Wachiraporn Toopaang, Thippawan Yoocha, Thippawan Yoocha, Chaiwat Naktang, Chaiwat Naktang, Nuchnudda Wichienchote, Phornsiri Pechsrichuang, Sithichoke Tangphatsornruang, Sithichoke Tangphatsornruang, Morakot Tanticharoen, Yu-Liang Yang, Yu-Liang Yang, Alongkorn Amnuaykanjanasin

“…Within the pks15 cluster, the UDP-glucosyl transferase gene Bbugt1 was consistently upregulated 3-fold in the WT in vivo compared to the WT in vitro armyworm group 48–96 h post-inoculation. In contrast, Bbugt1 was downregulated in Δpks15 in vivo compared to the WT in vivo during the same period. …”
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Molecular insights into the relationship between sustained CRP elevation and endothelial dysfunction in axial spondyloarthritis by Clementina López-Medina, Nuria Barbarroja, Alejandro Escudero-Contreras, Chary López-Pedrera, Carlos Perez-Sanchez, Pedro Segui, Eduardo Collantes, Jerusalem Calvo, Lourdes Ladehesa-Pineda, Desiree Ruíz-Vilchez, Laura Cuesta-López, Iván Arias-de la Rosa, Jesús Eduardo Martín-Salazar, Antonio Manuel Barranco, Miriam Ruiz-Ponce, María Ángeles Puche Larrubia, Rafaela Ortega, María Carmen Ábalos-Aguilera, Elena Moreno-Caño, Pedro Ortiz-Buitrago

“…Carotid intima-media thickness (CIMT) and microvascular endothelial function (post-ischaemic reactive hyperaemia) were measured. …”
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Dynamic UAV data fusion and deep learning for improved maize phenological-stage tracking by Ziheng Feng, Jiliang Zhao, Liunan Suo, Heguang Sun, Huiling Long, Hao Yang, Xiaoyu Song, Haikuan Feng, Bo Xu, Guijun Yang, Chunjiang Zhao

“…Most phenological monitoring methods are post–seasonal and heavily rely on high–frequency time–series data. …”
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Effects of intermittent theta burst to the left dorsolateral prefrontal cortex on brain volumes and neurometabolites in people with alcohol use disorder: a preliminary investigatio... by Timothy C. Durazzo, Timothy C. Durazzo, Lauren H. Beauregard, Meng Gu, Eric P. Kraybill, Brian D. P. Joseff, Amy A. Herrold, Amy A. Herrold, Keith Humphreys, Keith Humphreys, M. Windy McNerney, M. Windy McNerney, Brian Knutson, Claudia B. Padula, Claudia B. Padula

“…Bilateral volumes of the rostral and caudal middle frontal and superior frontal gyri left DLPFC neurometabolites were quantitated pre- and post-iTBS sessions.ResultsOver the 2-week assessment interval, significant volume increases were observed, collapsed across groups, in the bilateral rostral and caudal middle frontal and superior frontal gyri, as well as in the left DLPFC choline-containing compounds. …”
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Abstract 032: Ovine Models for Cerebral Venous Catheter Access: A Single Center Experience by José M Morales, Naoki Kaneko, Gary R Duckwiler

“…A coil (Stryker Target) was deployed extravascularly from the 0.017" microcatheter for post‐mortem characterization (figure 3). Conclusion One of three experiments met criteria for success. …”
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Regreening Practices and Effectiveness Evaluation for Rocky Slope Drawdown Zones in Pumped Storage Power Station Reservoirs by YANG Zhi-chao, MA Xiao-xiao, CHANG Shi-ju, TANG Yu-shuang, ZHAO Rui-yi, WAN Dan, ZHANG Qian-zhu

“…Plants exhibited strong resilience in terms of post-submersion recovery, expansion, and colonization, achieving an overall survival rate of 83.2%. …”
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Transhumanism and New Challenges in Political Theories by Matin Anjomrooz, Mohammad Khezri

“…Furthermore, transhuman technologies challenge national and cultural identities by fostering hybrid or post-human identities, necessitating policies that can maintain social cohesion while respecting diversity. …”
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Voluntary Activity Wheel Running Improves Hyperammonaemia‐Induced Skeletal Muscle Molecular and Metabolic Perturbations in Mice by Annette Bellar, Avinash Kumar, Khaviyaa Chandramohan, Saurabh Mishra, Muaz Alsabbagh‐Alchirazi, Artem Astafev, Pugazhendhi Kannan, Amy Attaway, Roman Kondratov, Thomas Jaramillo, Lopa Mishra, Takhar Kasumov, Nicole Welch, Srinivasan Dasarathy

“…Indirect calorimetry was performed pre‐ and post‐intervention. Mice were euthanized 4 weeks after the start of VWR/UA, and organs (including muscles) were harvested, weighed, and muscle histomorphometry performed for fibre diameter/type. …”
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Hs-CRP, Diabetic Status, and Adverse Events Among Patients Receiving Statin Therapy Following PCI—A Prospective Registry-Based Study by Chen X, Wang HY, Sun W, Lin Z, Qiao Z, Bian X, Yin D, Feng L, Zhu C, Song W, Wang H, Jia L, Dong Q, Dou K

“…Residual inflammatory risk, defined as persistent inflammation despite lipid-lowering therapy, differs from residual cholesterol risk, which refers to suboptimal lipid levels post-treatment. This study aims to evaluate the impact of T2DM on the relationship between residual inflammatory risk, as assessed by a simple, economical, and easily measurable biomarker—high-sensitivity C-reactive protein (hs-CRP)—and clinical outcomes in statin-treated coronary heart disease (CHD) patients with drug-eluting stent (DES) implantation.Patients and Methods: 8,628 individuals with CHD treated with statins and DES implantation at Fuwai Hospital were included. …”
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Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway by Yilin Fan, Yilin Fan, Weibing Lv, Weibing Lv, Xiaowei Li, Geri Wanma, Geri Wanma, Jian Li, Jian Li, Xianrong Xiong, Xianrong Xiong, Xiaoqiang He, Yanwen Wang, Shi Yin, Shi Yin, Wei Fu, Wei Fu, Honghong He, Honghong He, Yaqiu Lin, Yaqiu Lin, Daoliang Lan, Daoliang Lan, Yan Xiong, Yan Xiong

“…Artesunate (ART), derived from Artemisia annua and used for malaria treatment, shows potential as a frozen semen antioxidant.MethodsWe investigated the effects of various ART concentrations (0.2, 0.5, and 1.0 mM) on yak semen cryopreservation and examined the molecular mechanisms involved.ResultsPost-freezing, sperm quality markedly declined. However, 0.2 mM ART significantly improved sperm motility (both total and progressive) and reduced membrane damage. …”
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The role of ultra-high field MRI and image processing in the presurgical workup in MRI-negative focal epilepsy: A validated 7T MRI case study by Daniel Uher, Gerhard S. Drenthen, Christianne M. Hoeberigs, Rick H.G.J. van Lanen, Albert J. Colon, Roy A.M. Haast, Vivianne H.J.M. van Kranen-Mastenbroek, Guido Widman, Paul A.M. Hofman, Louis G. Wagner, Jan C. Beckervordersandforth, Jacobus F.A. Jansen, Olaf E.M.G. Schijns, Walter H. Backes

“…This case study illustrates that advanced image processing of ultra-high field structural and resting-state functional MRI scans may enhance the detection of subtle epileptogenic lesions in presurgical evaluation, potentially improving post-operative seizure outcome and associated quality of life.…”
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Case Report: “DEK::AFF2 fusion associated sinonasal carcinomas: a novel oncogenic driver and emerging therapeutic strategies” by Moritz Knebel, Moritz Knebel, Abbas Agaimy, Jan Philipp Kühn, Jan Philipp Kühn, Sandrina Körner, Sandrina Körner, Felix Braun, Felix Braun, Lukas Brust, Lukas Brust, Veronika Flockerzi, Veronika Flockerzi, Silke Wemmert, Silke Wemmert, Benedikt Balensiefer, Benedikt Balensiefer, Bernhard Schick, Umut Yilmaz, Umut Yilmaz, Malek Zaito, Malek Zaito, Alessandro Bozzato, Alessandro Bozzato, Maximilian Linxweiler, Maximilian Linxweiler

“…This allowed a shift to definitive chemoradiotherapy, with sustained disease-free status confirmed by a PET-CT three months post-treatment in July 2024. The second case involved a 66-year-old woman presenting with recurrent inverted papilloma affecting the sinonasal and tympanic regions. …”
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Protein oxidation and its effect on functional properties of livestock products during the processing and storage: A review by Jiamei Wang, Na Wu, Yao Yao, Shuping Chen, Lilan Xu, Yan Zhao, Yonggang Tu

“…The oxidation of proteins in livestock products readily occurs post-processing and storage through techniques such as freezing, cooking, ultrasonication, among others, leading to protein carbonylation and subsequent alterations in structure. …”
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Distal Radial Access and Women: Implications for Access Site Outcomes in Coronary Procedures by Ji Woong Roh, Seok‐Jae Heo, Oh‐Hyun Lee, Eui Im, Deok‐Kyu Cho, Jun‐Won Lee, Bong‐Ki Lee, Sang‐Yong Yoo, Sang Yeub Lee, Chan Joon Kim, Han‐Young Jin, Jin Sup Park, Jung Ho Heo, Do Hoi Kim, Jin Bae Lee, Dong‐Kie Kim, Jun Ho Bae, Sung‐Yun Lee, Seung‐Hwan Lee, Yongcheol Kim

“…Background We investigated the sex‐specific variations in distal radial access (DRA)–associated outcomes, as well as the factors influencing these outcomes, by utilizing a comprehensive real‐world registry. Methods In this post‐hoc analysis of the KODRA (Korean Prospective Registry for Evaluating the Safety and Efficacy of Distal Radial Approach) trial, we selected 4608 patients who underwent successful coronary procedures, including percutaneous coronary intervention or coronary angiography, via DRA. …”
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Single nuclear‐spatial transcriptomic sequencing reveals distinct puncture‐induced cell subpopulations in the intervertebral disc of a rat model by Guoyan Liang, Jing Tan, Chong Chen, Yuying Liu, Yongyu Ye, Xiaolin Pan, Qiujian Zheng, Yunbing Chang, Feng‐Juan Lyu

“…Results Puncture response regions were revealed on day 1 post‐puncture, for which oxidative stress emerged as a prominent pathway in a Stress Zone consisting of lipocalin‐2 (Lcn2)+ annulus fibrosus (AF) cells (AFC), which propagated and migrated into nucleus pulposus (NP), playing a key role in delivering injury signals and triggering pathological processes, including ferroptosis, fibrosis, and immune reactions. …”
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MINERALOGICAL AND GEOCHEMICAL EVIDENCE FOR MULTI-STAGE FORMATION OF THE CHERTOVO KORYTO DEPOSIT by Yu. I. Tarasova, О. T. Sotskaya, S. Yu. Skuzovatov, V. A. Vanin, Z. I. Kulikova, A. E. Budyak

“…In our study, we distinguish five mineral associations resulting from heterochronous processes that sequentially replaced each other:- The earliest association related with the quartz-muscovite-sericite metasomatism and the removal of REE and other elements from the rocks and their partial redeposition;- Metamorphic sulphidization presented by scattered impregnations of pyrrhotite, as evidenced by small lenses of pyrrhotite, which are considerably elongated (axes up to 0.7 cm long) along the foliation planes (Figs 3, a, b);- Ore mineralization represented by a superimposed hydrothermal gold association with arsenopyrite (Fig. 3, d);- Late chalcophilic mineralization formed at the final stage of hydrothermal-metasomatic process (Figs 3, e, f);- Post-ore silification.Geochemical characteristics. …”
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Venous microtrauma associated with pharmacomechanical catheter-directed thrombolysis in a large animal acute deep venous thrombosis model by Mohamed S. Zaghloul, Sophia R. Pyeatte, Sophia R. Pyeatte, Shahab Hafezi, Usama Ismail, Rodrigo Meade, Batool Arif, Roger Rowe, Luis Sanchez, Mohamed A. Zayed, Mohamed A. Zayed, Mohamed A. Zayed, Mohamed A. Zayed, Mohamed A. Zayed, Mohamed A. Zayed, Mohamed A. Zayed, Mohamed A. Zayed

“…Serial venograms assessed thrombus formation and post-treatment results, and then iliocaval venous segments were resected for histomorphic analysis.ResultsART significantly reduced thrombus in all pigs without complications (64.7% ± 9.7% vs. 16.1% ± 10.5%; P = 0.02). …”
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FACTORS ASSOCIATED WITH HEARING IMPAIRMENT IN INFANTS WHO RECEIVED THERAPEUTIC HYPOTHERMIA by М. Соломенко, О. Харитонова

“…Among SNHL cases, 4 exhibited post-ischemic cerebral lesions while 2 demonstrated moderate lateral ventricular dilatation. …”
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