Effect of antagomir-22-3p treatment on skeletal muscle growth in intrauterine growth-restricted lambs by S. K. Duckett, M. A. Greene, A. N. S. Udoka, R. R. Powell, T. F. Bruce, T. F. Bruce, J. L. Klotz

“…Muscle samples were collected 24 days post-injection to assess miR-22-3p levels and mRNA expression of potential miRNA targets.Results and discussionCell-free circulating miR-22-3p expression was more downregulated (P < 0.05) in NR-ANT22 lambs compared to that in CON-SHAM on d 14 after injection. …”
Get full text

Water footprint management in textile industry through Acid Blue 113 remediation using halloysite nanoclay as a sustainable adsorbent by Mohammed A. H. Dhaif Allah, Syed Noeman Taqui, Usman Taqui Syed, Syida Aameera Yakuth, Razia Sulthana, Rayees Afzal Mir, Akheel Ahmed Syed, Shareefraza J. Ukkund, Majed Alsubih, Saiful Islam, Wahaj Ahmad Khan

Get full text

Clinical Characteristics and Mechanism Discussion of Peripheral Nerve Injury in 2 Cases of Severe Viral Meningoencephalitis by Guo X, Zheng M, Wei Z, Song J, Wang X, Shen Z, Guo X, Zhang N, Xing Y, Zhang Y, Zhang W, Du R, Qiu B, Tian S, Wang Z

“…After treatment, the nerve damage improved, and the patient had a good prognosis post-discharge. Upon admission, Patient 2 exhibited viral meningoencephalitis symptoms, with elevated serum IL-8 and normal IL-6 levels; limb muscle strength and tone were normal. …”
Get full text

La teoría queer/cuir y feminista interseccional en los procesos migratorios: Las identidades de género y sexualidades en la movilidad transnacional by Gloria Cuesta Noguerales

“…Manalansan va a hacer hincapié en cómo las migraciones están impulsadas por el deseo de explorar identidades sexuales disidentes, entre otras motivaciones. Las feministas post/decoloniales, interseccionales y postestructuralistas han desafiado las jerarquías basadas en sexo/género, raza y clase, y su enfoque crítico ha influido profundamente en el ámbito de los estudios migratorios. …”
Get full text

Impact of CYP3A4 and ABCB1 genetic variants on tacrolimus dosing in Greek kidney transplant recipients by Anna Tsironi, Konstantinos Lazaros, Effrosyni Mendrinou, Marios Papasotiriou, Stavroula Siamoglou, Kyriaki Kydonopoulou, Anne John, Alexandra Gerou, Spyridon Gerou, Bassam R. Ali, Bassam R. Ali, Aristidis G. Vrahatis, George P. Patrinos, George P. Patrinos, George P. Patrinos, George P. Patrinos, George P. Patrinos

“…As a result, investigating the role of genetic variation in Greek transplant recipients becomes crucial to optimizing therapeutic strategies and enhancing the efficacy of immunosuppressive treatment.HypothesisGenetic variants which are known to influence the activity of enzymes or drug-transporters critical to tacrolimus pharmacokinetics, may significantly affect the required kidney post-transplant tacrolimus daily dose.AimTo assess the correlation of ABCB1 genetic variants (rs1128503, rs2229109) and CYP3A4 (rs2242480, rs4986910) with tacrolimus dose-adjusted trough concentration (C0/D), in Greek kidney transplant recipients.MethodsNinety-four unrelated Greek kidney transplant recipients were included in this study from the Department of Nephrology and Kidney Transplantation of the University General Hospital of Patras. …”
Get full text

Gut microbial dysbiosis exacerbates long-term cognitive impairments by promoting intestinal dysfunction and neuroinflammation following neonatal hypoxia-ischemia by Andi Chen, Chengqian Teng, Jianjie Wei, Xuyang Wu, Honghong Zhang, Pinzhong Chen, Dingliang Cai, Haitao Qian, Hui Zhu, Xiaochun Zheng, Xiaohui Chen

“…Collectively, these findings underscore the contribution of gut microbial dysbiosis post HI insult in activating the LPS/TLR4 signaling pathway, triggering intestinal inflammation and dysfunction, exacerbating systemic inflammation, and consequently worsening synaptic and cognitive impairments in neonatal HIBD rats. …”
Get full text

An Empirically Validated Framework for Automated and Personalized Residential Energy-Management Integrating Large Language Models and the Internet of Energy by Vinícius Pereira Gonçalves, Andre Luiz Marques Serrano, Gabriel Arquelau Pimenta Rodrigues, Matheus Noschang de Oliveira, Rodolfo Ipolito Meneguette, Guilherme Dantas Bispo, Maria Gabriela Mendonça Peixoto, Geraldo Pereira Rocha Filho

“…Baseline energy consumption was measured and compared with post-intervention usage to assess system impact. …”
Get full text

Efficacy and acceptability of different blood flow restriction training interventions during the rehabilitation of military personnel with lower limb musculoskeletal injuries: prot... by Alexander N Bennett, Peter Ladlow, Luke Hughes, Nick Caplan, Robert Barker-Davies, Luke Gray, Russ J Coppack, Robyn P Cassidy, Gavin Atkinson, Lauren Bradshaw, Janisha Chauhan, Kieran M Lunt

“…Low-load RT with blood flow restriction (BFR) can promote favourable morphological and physiological adaption, as well as elicit hypoalgesia in healthy and clinical populations (eg, post-operative), and has proven a viable option in military rehabilitation settings. …”
Get full text

Investigating the adsorption of acid blue 90 onto porous MIL53(Fe) and Cu-BTC sorbents: An examination of process parameters, isotherm modelling, and kinetic studies by Georges Teikam Kenda, Donald Raoul Tchuifon Tchuifon, Aurelien Bopda, Merdouce Dongmo, Idris-Herman Kuete Tiotsop, Kora Lucresse Tiomo Nguena, Cyrille Ghislain Fotsop, Nche George Ndifor-Angwafor, S. Mathada Basavarajaiah, Ahmad Hosseini-Bandegharaei

Get full text

Leaf wound induced ultraweak photon emission is suppressed under anoxic stress: Observations of Spathiphyllum under aerobic and anaerobic conditions using novel in vivo methodology... by Carl L Oros, Fabio Alves

“…Further examination of leaf wounding profile photon counts revealed that the pre-wounding basal state (aerobic and anoxic), the anoxic wounding state, and the post-wounding aerobic state statistics all approximate a Poisson distribution. …”
Get full text

Impact of a multi-component implementation strategy to increase outdoor free play opportunities in early childhood education and care (ECEC) services: the get outside get active (G... by Sze Lin Yoong, Nicole Pearson, Luke Giles, Hannah Lamont, Luke Wolfenden, Jannah Jones, Christophe Lecathelinais, Patti-Jean Naylor, Anthony Okely, Nicole Nathan, Kathryn Reilly, Rebecca Lorch, John Wiggers, Jacklyn Jackson, Melanie Lum, Karen Gillham, Alice Grady

“…Conclusions The implementation strategy significantly increased outdoor free play opportunities in ECEC services post-intervention, though the between group effects were not sustained at 18 months. …”
Get full text

The salvage therapy utilizing human umbilical cord-derived mesenchymal stem cells for the treatment of critically ill patients with COVID-19 by Weiqi Yao, Weiqi Yao, Weiqi Yao, Boran Li, Yingan Jiang, Qiaoyu Yuan, Qiaoyu Yuan, Wenjie Wu, Wenjie Wu, Ruizhen Hou, Ruizhen Hou, Qi Qi, Qi Qi, Haibo Dong, Haibo Dong, Yun Zhang, Yun Zhang, Yu Zhang, Yu Zhang, Yu Zhang, Yu Zhang, Yu Zhang

“…The efficacy was assessed by coagulation function (serum D dimer), inflammatory index (CRP and IL-6) and immune index (lymphocyte count, neutrophil count, CD4, CD19, and CD16 + 56), as well as chest computed tomography (CT) images. Post-infusion visits focused on oxygen saturation and progression of lung lesions.ResultsInfusions of hUC-MSCs were not associated with any serious adverse events. …”
Get full text

One-year recurrence rate of new-onset atrial fibrillation after acute myocardial infarction by Alicia Prieto-Lobato, Víctor Hidalgo Olivares, Manuel Gerónimo Pardo, Marta Cubells Pastor, Francisco Manuel Salmerón Martínez, Miguel José Corbí-Pascual

“…The primary outcome was the recurrence of AF within the first year post-discharge. Secondary outcomes included all-cause mortality, cardiovascular mortality, and a composite of major adverse cardiovascular events. …”
Get full text

Persistence of Ebola virus in semen among Ebola virus disease survivors in Sierra Leone: A cohort study of frequency, duration, and risk factors. by A E Thorson, G F Deen, K T Bernstein, W J Liu, F Yamba, N Habib, F R Sesay, P Gaillard, T A Massaquoi, S L R McDonald, Y Zhang, K N Durski, S Singaravelu, E Ervin, H Liu, A Coursier, J E Marrinan, A Ariyarajah, M Carino, P Formenty, U Ströher, M Lamunu, G Wu, F Sahr, W Xu, B Knust, N Broutet, Sierra Leone Ebola Virus Persistence Study Group

“…<h4>Background</h4>Sexual transmission chains of Ebola virus (EBOV) have been verified and linked to EBOV RNA persistence in semen, post-recovery. The rate of semen persistence over time, including the average duration of persistence among Ebola virus disease (EVD) survivors, is not well known. …”
Get full text

Uso de la videocolonoscopia para el tamizaje del cáncer colorrectal: estudio descriptivo by F.E. Jabif, P.N. Cherne, C. Pintos, J.A. Pollán, A. Murujosa

“…A total of 118 cases of CRC were diagnosed, as a result of the first colonoscopy. The post-colonoscopy hospitalization rate was 1.14%. …”
Get full text

Facile modification using organic acid molecules to neutralize residual alkaline compounds for stabilizing LiNi0.95Co0.04Mn0.01O2 cathode material by Chao Zhao, Xiangshao Yin, Yuanyuan Huang, Xinyu Zhang, Weihong Jiang, Zhuo Zhou, Wenhui Tu, Xianshu Wang, Ding Wang, Jianguo Duan

“…Herein, we propose neutralizing residual alkaline compounds with 3-thiopheneboronic acid (3-TBA) to improve the performance of LiNi0.95Co0.04Mn0.01O2 (NCM) cathode material, a facile strategy that does not require any post-treatment. The suggested reaction yields a uniform and thin organic-modified layer on the surface of the NCM cathode, improving its chemical stability toward the electrolyte, as demonstrated by multiple characterization methods. …”
Get full text

Efficacy and safety of HSK21542 for pruritus management in hemodialysis patients: a multicenter, randomized, double-blind, placebo-controlled trial by Ming-Ming Pan, Min Gao, Li Zhou, Yan Xu, Li Yao, Chao-Qing Wu, Chang-Lin Mei, Chang-Lin Mei, Zhan-Zheng Zhao, Dong Sun, Tian-Jun Guan, Qin-Kai Chen, Ming Shi, Hui Xu, Ya-Ming Li, Wan-Yun Zhao, Rui Yan, Bi-Cheng Liu

“…This Phase II trial evaluated the efficacy and safety of HSK21542, a selective kappa-opioid receptor agonist, in managing CKD-aP.MethodsAdult patients on hemodialysis with moderate to severe pruritus, were randomized 1:1:1 to placebo, or HSK21542 (0.3 μg/kg or 0.6 μg/kg) administered thrice weekly post-dialysis for 12 weeks. The primary endpoint was the change from baseline in the weekly mean of the worst itching intensity Numerical Rating Scale (WI-NRS) score at week 12. …”
Get full text

GENDER-RELATED CHARACTERISTICS OF AFFECTIVE DISORDERS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION by S. Yu. Mukhtarenko, T. M. Murataliev, Yu. N. Nekludova, Z. T. Radzhapova, V. K. Zventsova

“…Mortality was higher in the female group compared to the male group: overall (19.4 % vs. 5.7 %, р &lt;0.05), hospital (8.3 % vs. 1.1 %, р &lt;0.05), and post-hospital (11.1 % vs. 4.5 %,  р &gt;0.05) mortality, respectively. …”
Get full text

EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures by María Victoria Villar, Katerina Cernochova, Jaime Cuevas, Antonio Gens, Natalia Gimeno, Caroline Graham, Jon Harrington, Vlastislav Kašpar, Stephan Kaufhold, Olivier Leupin, David Mašín, Jan Najser, Markus Olin, Heini Reijonen, Šárka Šachlová, Sergey Sayenko, Daniel Svensson, Jiri Svoboda, Gianni Vettese, Janne Yliharju, Borys Zlobenko

“…Bentonite was also subjected to hydration under a thermal gradient in field and laboratory tests. No post-mortem structural modifications of the smectite were observed; however, dissolution and precipitation of species occurred, conditioned by the type of bentonite and hydration water. …”
Get full text

Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells by Valeria Saar-Kovrov, Aleksandra Pawlowska, Adrien Guillot, Marion J. J. Gijbels, Marion J. J. Gijbels, Marion J. J. Gijbels, Judith C. Sluimer, Judith C. Sluimer, Lieve Temmerman, Pieter Goossens, Barend M. E. Mees, Frank Tacke, Vera Jankowski, Joachim Jankowski, Joachim Jankowski, Marjo M. P. C. Donners, Erik A. L. Biessen, Erik A. L. Biessen

“…IntroductionCarbamylation is a non-enzymatic post-translational protein modification common in patients with uremia that causes pro-atherogenic alterations in plasma proteins. …”
Get full text