The Dynamic Relationship Among Atrial Pacing, Premature Atrial Beats, Mode Switching, and Atrial High-Rate Episodes in Patients with Sick Sinus Syndrome by Barış Yaylak, Fuat Polat, Cuma Süleymanoğlu

“…Conclusion: This study highlights a time-dependent relationship between pacing parameters and AHREs in patients with SSS. The early post-implantation periods showed significant correlations, which diminished over time. …”
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The effect of dental caries and restorative biomaterials on IL-1 β and TNF-α levels in the gingival crevicular fluid by Stefanović Vladimir, Taso Ervin, Kanjevac Tatjana, Abazović Džihan, Rakić Mia, Petković-Ćurčin Aleksandra, Acović Aleksandar, Vojvodić Danilo

“…GCF samples were collected from 90 periodontally healthy patients demonstrating at least one tooth with proximal caries and one intact tooth, at the baseline, 7 and 30-days post-treatment. The biomarkers’ profile was investigated in relation to different levels of caries extension (superficial, pulpitis, gangrenous, root affection), defect size, and restorative biomaterial. …”
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Impact of diverse irrigation water sources on olive oil quality and its physicochemical, fatty acids, antioxidant, and antibacterial properties by Noureddine Benguennouna, Djilali Benabdelmoumene, Said Dahmouni, Zineb Bengharbi, Mohamed Bouzouina, Wasim S. M. Qadi, Esraa Adnan Dawoud Dawoud, Ebtesam Al-Olayan, Andres Moreno, Ahmed Mediani

“…Treated wastewater demonstrated distinct water quality characteristics, including elevated temperature (15.00 °C), chemical oxygen demand (COD: 58.38 mg/L), biochemical oxygen demand (BOD5: 29.00 mg/L), ammonium (15.60 mg/L), nitrite (2.55 mg/L), suspended solids (14.00 mg/L), pH (7.40), and conductivity (2.80 µS/cm), reflecting residual organic material and ionic content post-treatment. Heavy metal concentrations in all water sources were within permissible limits for irrigation and drinking purposes, affirming their safety for agricultural use. …”
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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT) by Beatriz Arce-López, Guadalupe X. Bazan, Susana Molina, Maria Carmen Crespo, María García-Beccaria, Silvia Cruz-Gil, Cristina M. Fernández-Díaz, Ana Ramírez de Molina, Ricardo Ramos-Ruiz, Maria Isabel Espinosa-Salinas

“…In particular, the study group exhibited a reduction in triglyceride levels very close to significance (baseline mean ± SEM: 69.59 ± 6.98 mg/dL; post-intervention: 62.80 ± 5.14 mg/dL; p = 0.053), while the control group did not experience a significant variation. …”
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Oxidative stress index of porcine follicular fluid influences meiotic maturation and embryo development during in vitro culture by Bin Liu, Takeshige Otoi, Zhao Namula, Oky Setyo Widodo, Maki Hirata, Aya Nakai, Qingyi Lin, Yuichiro Nakayama, Megumi Nagahara, Fuminori Tanihara

“…Materials and Methods: Oocytes were matured in IVM media supplemented with 30% pFF classified into low (OSI 19), medium (OSI 22), and high (OSI 25) oxidative stress groups, based on the ratio of diacron-reactive oxygen metabolites to biological antioxidant potential. Post-IVM, oocytes were assessed for meiotic stage, DNA fragmentation, reactive oxygen species (ROS), and glutathione (GSH) levels. …”
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Sistemas de siembra de Cratylia argentea cultivar Veranera en dos localidades del valle del río Cauca, Colombia Sowing systems of Cratylia argentea cultivar veranera in two localit... by Jaime Rosero Alpala, Sanín Ortiz Grisales, Luís Horacio Franco, Michael Peters, Gerardo Ramírez

“…The emergency fluctuated among 85-97% y 78-92% to those 25 y 35 days post field for Quilichao and Palmira respectively. …”
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Comparison of Oliceridine and Morphine in Postoperative Analgesia in Laparoscopic Total Hysterectomy, a Randomized Double-Blind Controlled Trial by Duan J, Wang X, Hou C, Yu T, Ju X, Wang S

“…Exploratory indicators including hemodynamic parameters and peripheral capillary oxygen saturation (SpO2) post intravenous analgesic loading dose. Safety indicators represented by the incidence of adverse events occurring within 72 hours postoperatively.Results: Group O demonstrated superior early analgesia with lower resting NRS (1.0 [1.0,1.0] vs 1.5 [1.0,2.0]; P = 0.019) and cough NRS (1.0 [1.0– 2.0] vs 2.5 [1.0– 3.0]; P = 0.003) at 0.5 h compared with group M, and analgesic efficacy was comparable thereafter (all P > 0.05). …”
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MRI monitoring of USPIO-labeled BMSCs combined with alginate scaffold for cartilage defect repair by Shanyu Lu, Shanyu Lu, Zhenyu Liu, Zhenyu Liu, Meiling Qi, Meiling Qi, Haocheng Zhen, Jing Luo, Yingchao Wang, Yingchao Wang, Le Chang, Le Chang, Xiaolong Bai, Xiaolong Bai, Yingguang Jiao, Yingguang Jiao, Xinyao Chen, Xinyao Chen, Junping Zhen, Junping Zhen

“…T2 mapping MRI was performed at weeks 1, 2, and 4 post-surgery to evaluate the repair process, followed by histological analysis to confirm the outcomes.ResultsBMSCs significantly promoted cartilage defect repair and accelerated the degradation of sodium alginate scaffolds. …”
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An injectable and dual-crosslinked hydrogel for controlled and permanent vascular embolization by Xin Wang, Hantao Yang, Yaoben Wang, Yang Wang, Xuanbo Hu, Jiaxin Huang, Zhiyong Chen, Yu Chen, Jiandong Ding, Lin Yu

“…Furthermore, an oily contrast agent with an ultrahigh iodine amount (>60 wt%) is developed and incorporated into DC-gel to endow it with long-lasting imaging capabilities for real-time and post-operative visualization. In vivo experiments conducted on rabbit artery, vein and tumor models confirm that our DC-gel system achieves persistent embolization without recanalization or non-target embolization, which stems from its superior mechanical stability and long-term persistence obtained by the dual crosslinking strategy plus a moderate fibroinflammatory response induced by the poly(D-amino acid) component. …”
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Application of the Kirkpatrick model in the pediatric surgical nurse specialist training program (柯氏模型在小儿外科专科护士培训中的应用) by CHEN Qiqi (陈琪琦), LI Gefang (李各芳), LIU Rong (刘荣)

“…Implementation outcomes revealed: Reaction-level evaluation demonstrated high satisfaction among trainees across all three sessions; Learning-level assessment indicated significantly higher theoretical test scores post-training compared with pre-training baselines (P＜0. 05); Behavior-level feedback from both clinical instructors and trainees confirmed improvements in professional attitudes and job competencies; Results-level analysis showed substantial enhancement of core competencies among specialist nurses during later training phases. …”
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The Relationship of Insulin Resistance and Systemic Inflammation with Cardiovascular Outcomes in Non-Diabetic Patients Undergoing Coronary Artery Bypass Grafting by Xie Y, Chen H, Gao Y, He H, Wang Z, Zhang Y, Zhou Q, Liu L, Zheng J

“…This study investigates the relationship between IR and systemic inflammation and evaluates how systemic inflammation affects the correlation between IR and prognosis in non-diabetic patients undergoing coronary artery bypass grafting (CABG).Methods: This study enrolled 1,658 patients post-CABG. IR was assessed via the estimated glucose disposal rate (eGDR), and systemic inflammation was measured by C-reactive protein (CRP) levels. …”
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Percutaneous Coronary Intervention Outcomes by 5 Major Race and Ethnic Subgroups by Arjun B. Kapoor, MD, Serdar Farhan, MD, Manish Vinayak, MD, Samantha Sartori, PhD, Yihan Feng, MS, Yash Prakash, MD, Roxana Mehran, MD, Annapoorna Kini, MD, Deepak L. Bhatt, MD, MPH, MBA, Samin K. Sharma, MD

“…Additionally, socioeconomic status (SES) further complicates outcomes, with low SES serving as an independent predictor of adverse outcomes post-PCI. Objectives: This study aimed to analyze PCI outcomes across 5 racial and ethnic groups—White, Black, Hispanic, South Asian, and East Asian populations—while accounting for comorbidities and SES to better understand how race and ethnicity influence cardiovascular outcomes. …”
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Ear reconstruction after traumatic injuries Reconstruções auriculares após lesões traumáticas by José Carlos da Silva, Waldivino Guimarães Filho, Bruno Granieri de Oliveira Araújo

“…METHODS: A retrospective cross-sectional study was performed, including cases of post-traumatic ear reconstruction in which costal cartilage graft was employed; the study took place at Hospital Geral de Goiânia Dr. …”
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COVID-19 Pandemic-to-Endemic Transition in Indonesia: What Does the Future Hold? by Robert Sinto

“…Prabowo, et al. enriched our understanding on usage of telemedicine to monitor post COVID-19 condition in Indonesian populations. …”
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SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults by Carolyn A. Cohen, Ludivine Grzelak, Susan S. Chiu, David SC Hui, Mike YW Kwan, Owen TY Tsang, Wai Hung Chan, Yat Sun Yau, Kelly WK Lee, Masashi Mori, Gaya K. Amarasinghe, Samuel MS Cheng, Leo LM Poon, Malik Peiris, Sophie A. Valkenburg

“…We used plasma samples from an infection and vaccination-naive cohort study with RT-PCR confirmed ancestral B.1* SARS-CoV-2 virus infection with asymptomatic or mild disease, collected in Hong Kong between March to December 2020, from acute (0–14 days post infection) to convalescent (15–206 days) timepoints. …”
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Change trajectory of dyadic coping and subjective well-being in patients with malignant bone tumors based on cross-lagged panel model and latent growth model: a longitudinal study by Rui Li, Chun-yan Zhang, Yue Wu, Yao Wang, Yi-fan Li, Xiao-juan Fan, Hong Song

“…Notably, the initial level of subjective well-being was able to positively predict the developmental rate of dyadic coping (β = 0.294, p < 0.001).ConclusionThe results demonstrated a notable increase in dyadic coping and subjective well-being in patients with malignant bone tumors from the time of diagnosis to 3 months post-diagnosis. Furthermore, there was a discernible correlation between dyadic coping and subjective well-being in patients with malignant bone tumors.…”
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Efficacy and Safety of Lenvatinib Plus Programmed Death-1 Inhibitors with or Without Transarterial Chemoembolization in the Treatment of Unresectable Hepatocellular Carcinoma by Jin M, Jiang ZQ, Qin JH, Qin HX, Jiang KW, Ya HX, Gu J, Gui MR, Li YH, Xu LK, Fu HX, Xiao XH, Li SQ

“…Factors influencing survival rates were analyzed using Cox regression, and adverse events (AEs) were documented and assessed.Results: Before PSM, the T+L+P group showed significantly higher ORR (64.1% vs 44.4%, p < 0.05), longer median PFS (14.3 vs 9.6 months, p < 0.05), and longer median OS (24.6 vs 19.5 months, p < 0.05) compared to the L+P group. Even post-PSM, the T+L+P group showed significantly better OS and PFS compared to the L+P group (mOS: 28.0 vs 17.6 months p=0.0011, mPFS: 15.8 vs 9.3 months, p < 0.05). …”
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m6A-lncRNA landscape highlights reduced levels of m6A modification in glioblastoma as compared to low-grade glioma by Giedrius Steponaitis, Rugile Dragunaite, Rytis Stakaitis, Amit Sharma, Arimantas Tamasauskas, Daina Skiriute

“…Cox regression analysis showed that the status of lncRNAs m6A modifications had no significant value in predicting post-surgical survival time in our GB or LGG cohorts. …”
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Experience in Assessing the Emotional Intelligence of University Graduates in the Specialty “Business Informatics” by K. K. Kuchmezov, S. I. Neizvestny

“…Business practice shows that in the conditions of post-pandemic and turbulence of the environment, the elements of emotional and professional “burnout” of employees significantly increase, which leads to a decrease in productivity and quality of work. …”
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DTL dose-dependent control of sex-dimorphic ferroptosis in liver ischemia reperfusion injury by Xiang Huang, Junfu Fan, Kunxuan Zhu, Xiangjun Wu, Chunhui Jiang, Junhao Chen, Jiebin Qiu, Lian Duan, Zhicheng Hu, Xixi Chen, Bin Zhou, Jingling Shen, Weitao Cong

“…Here, using multi-omics integrative analysis, we identified the denticleless E3 ubiquitin protein ligase (DTL)-homeobox protein prospero-related homeobox 1 (PROX1) signaling axis as a key determinant of the sexual dimorphism associated with hepatic I/R injury. High post-hepatectomy DTL levels were accompanied by deteriorated hepatectomy patient function and correlated with augmented hepatocellular death. …”
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