Fibrocartilage repair involves chronic cellular senescence in a rat model of bone marrow stimulation by Luke Childress, Landon B. Gatrell, Hong Wu, Elisabeth Ferreira, Intawat Nookaew, Ryan M. Porter

“…Objective: Cellular senescence has been implicated in the progression of post-traumatic osteoarthritis, but any role in pre-osteoarthritic cartilage repair is unknown. …”
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PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience

“…No major B-AEs or T-AEs were reported during a median post-assay follow-up of 5 months (range 1.1–20.4). …”
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Resting-State Activity Changes Induced by tDCS in MS Patients and Healthy Controls: A Simultaneous tDCS rs-fMRI Study by Marco Muccio, Giuseppina Pilloni, Lillian Walton Masters, Peidong He, Lauren Krupp, Abhishek Datta, Marom Bikson, Leigh Charvet, Yulin Ge

“…In HCs, fALFF increased in the right pre- and post-central gyrus whilst it decreased in subcortical regions. …”
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Machine learning-based prognostic prediction for acute ischemic stroke using whole-brain and infarct multi-PLD ASL radiomics by Zhenyu Wang, Chaojun Jiang, Xianxian Zhang, Tianchi Mu, Qingqing Li, Shu Wang, Congsong Dong, Yuan Shen, Zhenyu Dai, Fei Chen

“…This study aimed to assess the predictive value of radiomics features from whole-brain and infarct cerebral blood flow (CBF) images using multiple post-labeling delay arterial spin labeling (multi-PLD ASL), and to develop a prediction model incorporating clinical risk factors. …”
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Written Exposure Therapy for PTSD Integrated with Cognitive Behavioral Coping Skills for Cannabis Use Disorder After Recent Sexual Assault: A Case Series by Christine K. Hahn, Selime R. Salim, Emily L. Tilstra-Ferrell, Kathleen T. Brady, Brian P. Marx, Barbara O. Rothbaum, Michael E. Saladin, Constance Guille, Amanda K. Gilmore, Sudie E. Back

“…<b>Results</b>: This case series describes the novel intervention and examines clinical outcomes post-treatment and at the 1-month follow-up. Past-week PTSD symptoms (based on a clinical interview) and past-month cannabis use decreased among all participations after receiving STEPS. …”
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DRUG TREATMENT OF PATIENTS WITH THE HISTORY OF ACUTE STROKE: DATA OF THE PILOT PHASE OF THE OUTPATIENT REGISTRY «REGION» by S. A. Boytsov, M. M. Loukianov, S. S. Yakushin, S. Yu. Martsevich, L. V. Stakhovskaya, A. N. Vorobyev, A. V. Zagrebelnyy, A. N. Kozminsky, K. A. Moseichuk, K. G. Pereverzeva, E. A. Pravkina, E. N. Belova, V. G. Klyashtorny, E. V. Kudryashov, E. Yu. Okshina, A. D. Deev

“…Drugs with a proven beneficial effect on the prognosis in the post-stroke period were prescribed significantly (p and after 2 years – in the AS-FA registry, the frequency of the therapy was not significantly different from the frequency of prescribing at the stage of inclusion in the registers, with the exception of statins (they were taken 1.7 and 1.5 times less frequently). …”
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In vitro evaluation of hydro-ethanolic seed extract of Zanthoxyllum armatum DC to establish its mechanism of action for paralysis of Paramphistomum cervi in continuation with in vi... by Hazarika S., Barua C. C., Mohan P., Das A., Hazorika M., Tamuly S., Pathak P., Borah B., Phangchupi D., Chakraborty A., George S.

“…An in vivo experiment of HESEZA @ 150 and 250 mg/kg body weight in naturally infected goats were accomplished with complete reduction of EPG count on 28th day of post-treatment of the extract @ 250 mg/kg b. wt. …”
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Comparison of biodegradable and metal occluders in patients with PFO and migraine: study design and rationale of BioMetal Trial by Ziping Li, Jie Dong, Jing Dong, Yiming Yan, Manchen Gao, Fang Fang, Fengwen Zhang, Wenbin Ouyang, Shouzheng Wang, Chuangshi Wang, Xiangbin Pan, BioMetal investigators

“…A total of 400 participants will be enrolled, randomized 1:1 to receive either the biodegradable or metal devices, and followed up for 24 months post-randomization. The primary endpoint is the change in monthly migraine days at 12 months compared to baseline. …”
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AAV-mediated transduction of songbird retina by Pranav Kumar Seth, Pranav Kumar Seth, Dominik Heyers, Dominik Heyers, Baladev Satish, Ezequiel Mendoza, Katrin Haase, Lisa Borowsky, Isabelle Musielak, Karl-Wilhelm Koch, Karl-Wilhelm Koch, Regina Feederle, Constance Scharff, Karin Dedek, Karin Dedek, Henrik Mouritsen, Henrik Mouritsen

“…Subsequent immunohistochemical analyses revealed that the AAV2/9-EGFP serotype almost exclusively targeted photoreceptors: rods, various single cones (UV, blue, green, and red cones), and both (accessory and principal) members of double cones.DiscussionThe consistently high and photoreceptor-specific transduction efficiency makes the AAV2/9 serotype a powerful tool for carrying out genetic manipulations in avian retinal photoreceptors, thus opening a wealth of opportunities to investigate physiological aspects underlying retinal processing in birds, such as physiological recordings and/or post-transductional behavioural readouts for future vision-related research.…”
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Modifying lumbar flexion pain thresholds in patients with chronic low back pain through visual-proprioceptive manipulation with virtual reality: a cross-sectional study by Jaime Jordán-López, María D. Arguisuelas, Julio Doménech, M. Lourdes Peñalver-Barrios, Marta Miragall, Rocío Herrero, Rosa M. Baños, Juan J. Amer-Cuenca, Juan F. Lisón

“…One-way ANOVA with Bonferroni post-hoc tests examined differences among conditions, and three two-sample t-tests explored whether individuals with higher pain, kinesiophobia, and catastrophizing were more affected by visual-proprioceptive manipulation. …”
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Assessment of the medical radiation and non-radiation risks for the patients undergoing the surgical gender reassignment from female to male by V. V. Safronov, A. A. Davydov, A. V. Vodovatov, O. I. Startseva, A. M. Biblin, L. V. Repin

“…Radiation risks are equal to or even exceed (for the final stages of the gender reassignment surgery) the other risks of mortality from the non-radiation factors (anesthesia – 5,4×10-5, thrombosis – 2×10-5, post-surgical complications – 6×10-2). The reduction of suicide risks, as a result of the treatment, outweighs all other risk factors and justifies the gender reassignment surgery. …”
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Results of kidney transplantation in patients with end-stage renal failure caused by autosomal dominant polycystic kidney disease by V. S. Daineko, A. N. Ananiev, E. S. Nevirovich, A. E. Skvorcov, S. A. Budylev, А. N. Selivanov, M. M. Moskalenko, V. A. Manukovskiy, O. N. Reznik

“…Among patients whom polycystic-changed kidneys removed, there is a more favorable course of the post-transplant period due to the low frequency of infectious complications. …”
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Accuracy Investigation of PPP Method Versus Relative Positioning Using Different Satellite Ephemerides Products Near/Under Forest Environment by Taylan Ocalan, Bahattin Erdogan, Nursu Tunalioglu, Utkan Mustafa Durdag

“…In recent years, due to the increase in providers of orbit and clock corrections of satellites for data evaluation in real-time and post-processing the method of Precise Point Positioning (PPP) using measurements of Global Navigation Satellite System (GNSS) and Web-based online positioning services have become widespread. …”
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The Effectiveness of Emotion-Focused Therapy on Pain Anxiety and Resilience in Patients with Migraine by Hamid Reza Arab Bafrani, Hasan Rezayi, Ahmad Sobhani

“…Specifically, the mean pain anxiety and resilience in the intervention group decreased and increased, respectively, in the post-test and follow-up, whereas no significant changes were observed in the control group (Table 1).The Shapiro-Wilk test confirmed the normal distribution of data in both groups across all assessment stages. …”
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TÜKETİCİ ETNOSENTRİZMİ: BEYAZ EŞYA VE İÇECEK SEKTÖRLERİNDE KARŞILAŞTIRMALI BİR SAHA ARAŞTIRMASI by T. Şükrü Yapraklı, Ercan Keser

“…Verilerin analizinde aritmetik ortalama, frekans dağılımı, tek yönlü ve iki yönlü varyans analizleri ve post hoc testinden yararlanılmıştır. Tüketici etnosentrizm düzeyi, her bir maddeye verilen cevapların ortalamalarının toplamının, alınabilecek en yüksek değerle karşılaştırılması sonucunda elde edilmektedir. …”
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Analysis of influencing factors on recurrence and metastasis of pT1b ~ pT4aNOM0 esophageal squamous cell carcinoma after radical surgery in Northeast Sichuan region by Wenxia Ren, Lei Yu, Yu Cui, Daiyuan Ma

“…Univariate analysis revealed that T stage, TNM stage, histological grade, and gross tumor type were factors influencing post-operative disease-free survival (all P < 0.05). …”
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Integrating vosoritide therapy with limb surgery in paediatric patients with achondroplasia: real-life experiences by Anna Elsa Maria Allegri, Maria Francesca Bedeschi, Maria Beatrice Bocchi, Valentina Camurri, Michaela Veronika Gonfiantini, Chiara Leoni, Milena Mariani, Osvaldo Palmacci, Matteo Porro, Simone Riganti, Caterina Tedesco, Berardo Rinaldi, Emanuela Scarano, Concetta Schiavariello, Angelo Selicorni, Stefano Stagi, Fabio Verdoni, Giuseppe Zampino, Mohamad Maghnie, Roberta Onesimo

“…Recently, C-type natriuretic peptide (CNP) has been explored as a potential treatment, aiming to counteract the molecular activity driven by FGFR3. Although post-market and real-world data on the drug are still limited, many questions remain about the potential for combining pharmacological and surgical therapies and how this might influence patient outcomes. …”
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The choice of adjuvant radiotherapy in pancreatic cancer patients after up-front radical surgery. by Xia Xiao, Pei Huang, Xiao-Ting Xu

“…These findings may contribute to the development of personalized selection criteria for adjuvant radiotherapy in post-surgical pancreatic cancer patients.…”
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Skin Microcirculatory Parameters as Diagnostic Markers of Central and Cerebral Circulatory Disorders in Hemorrhagic Shock by I. A. Ryzhkov, N. V. Golubova, K. N. Lapin, S. N. Kalabushev, V. V. Dremin, E. V. Potapova, A. V. Dunaev, V. T. Dolgikh, V. V. Moroz

“…At stage 3, parameters of post-occlusive reactive hyperemia (PORH) in hindlimb skin were additionally assessed. …”
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Impact of circuit configuration on the mechanical performance of CPAP therapy devices: an experimental study by Margherita De Luca, Margherita De Luca, Andrea Formaggio, Andrea Formaggio, Mara Terzini, Mara Terzini, Simone Borrelli, Simone Borrelli, Giovanni Putame, Giovanni Putame, Francesca Moretto, Francesca Moretto, Teresa Esposito, Teresa Esposito, Rosanna Vaschetto, Rosanna Vaschetto, Umberto Morbiducci, Umberto Morbiducci, Carlo Olivieri, Alberto L. Audenino, Alberto L. Audenino

“…Mask and helmet interfaces were tested, and healthy, post-surgery and ARDS respiratory conditions were simulated. …”
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