MOLECULAR MECHANISMS DEFINING APPLICATION OF GLYCINE AND ZINC COMBINATIONIN CORRECTION OF STRESS AND ANXIETY MAIN MANIFESTATIONS by V. N. Shishkova, Y. R. Nartsissov, V. Y. Titova, E. V. Sheshegova

“…The replenishment of the glycine and zinc combined deficiency is an important element in the correction of a post-stress dysfunction of the central nervous system. …”
Get full text

THE INFLUENCE OF CORONARY BYPASS ON ENDOTHELIAL AND ERECTILE DYSFUNCTION IN ISCHEMIC HEART DISEASE by S. A. Pomeshkina, E. V. Pomeshkin, T. Yu. Sergeeva, I. N. Sizova, O. L. Barbarash

“…In all patients we used questionnaire “International Index of Erectile dysfunction” (IIED), registration of nocturnal penile tumescenses (NPT), post compression tests on brachial and cavernous arteries. …”
Get full text

CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage by Justin Van Riper, Arleth O. Martinez-Claros, Lie Wang, Hannah E. Schneiderman, Sweta Maheshwari, Monica C. Pillon

“…Abstract The SLFN14 endoribonuclease is a post-transcriptional regulator that targets the ribosome and its associated RNA substrates for codon-bias translational repression. …”
Get full text

Clinical and pathological analysis of primary well-differentiated neuroendocrine tumors in the kidney- a case series by Dan Yuan, Jing Wu, Dong-Yue Wang, Jin-Jing Wang

“…During follow-up (1–77 months), one patient developed liver metastasis at 50 months post-operation (stabilized with PRRT), while others showed no recurrence. …”
Get full text

Biaxial flexural strength of different types of monolithic zirconia by Shereen Ahmed Nossair, Tarek Salah, Kamal Khaled Ebeid

“…Results:  One-way ANOVA revealed significant differences among the 12 groups. Tukey post-hoc tests revealed no significant differences between the groups 3, 4, ,7 ,8 11, and 12. …”
Get full text

Behaviour of FRP -confined mine pillar under compressive loading: Laboratory tests by Honglin Liu, Jiajie Tian, Yang Xia, Qinlong Ran, Hongchao Zhao

“…UPF specimens show localized tensile fractures with rapid crack propagation from stress concentration, whereas FRP cylindrical specimens (UCF) display smoother FRP rupture surfaces and 29° tensile-shear failure in rock cores; (3) Both UPF and UPFW exhibit multi-peak behavior, transitioning from rock-core-dominated initial peaks to FRP-dependent subsequent peaks, where cross-section geometry and high-water material critically influence post-peak performance; (4) All UW, UPW, and UCF specimens develop characteristic V-shaped displacement zones during failure but exhibit distinct damage evolution patterns, revealing FRP confinement’s critical role in regulating V-zone formation by altering damage propagation paths and energy release behaviors.…”
Get full text

Generative Artificial Intelligence in Computer Programming: Does It Enhance Learning, Motivation, and the Learning Environment? by Claudio Cubillos, Rafael Mellado, Daniel Cabrera-Paniagua, Enrique Urra

“…An experiment was conducted with 40 computer engineering students divided into two groups: one using GenAI (Google Gemini 1.5) and another employing educational videos. Pre- and post-tests of knowledge and the Intrinsic Motivation Inventory (IMI) were applied to evaluate learning, intrinsic motivation, and the learning environment. …”
Get full text

Experimental study on the resistance of asphalt mixtures to permanent deformation and its relation to mechanical behavior of pavement structures by Thanh Chung Do, Tan Hau Nguyen, Van Long Nguyen

Get full text

Evaluation of Walkability Index for Embedded Community Services from an Age-Friendly Perspective: A Case Study of Mapple Community in Chengdu, China by Jing Yang, Yuqiu Wu, Xuemei Chen, Binjie Luo, Ran Wu, Rong Lin

“…The results highlight that elderly residents prioritize healthcare facilities (weight = 0.22), while adolescents rely heavily on cultural–recreational amenities (weight = 0.32). Post-renewal walkability scores in core areas increased by 52.3%, yet persistent peripheral disparities underscore intergenerational accessibility gaps. …”
Get full text

Prevalence and associated risk factors of human immunodeficiency virus-associated Kaposi’s sarcoma among patients receiving care at Cancer Diseases Hospital, Lusaka, Zambia by Stella Mankuce, Victoria Mwiinga-Kalusopa, Ruth Wahila

Get full text

The piRNA protein Asz1 is essential for germ cell and gonad development in zebrafish and exhibits differential necessities in distinct types of germ granules. by Adam Ahmad, Yoel Bogoch, Gal Shvaizer, Noga Guler, Karine Levy, Yaniv M Elkouby

“…Mechanistically, we provide evidence to conclude that zygotic Asz1 is not required for primordial germ cell specification or migration to the gonad, but is essential during post-embryonic gonad development, likely by suppressing the expression of germline transposons. …”
Get full text

Pulp tissue dissolution capacities of two hypochlorite-based irrigants at different temperatures: an in vitro study by Damla Erkal, Yunus Emre Çakmak, Ana Maria Pistol, Kürşat Er

“…Statistical analysis included the Shapiro-Wilk test for normality, the Scheirer-Ray-Hare test for overall group comparison, and the Mann-Whitney U test for post hoc analysis. Results Tissue dissolution significantly varied depending on both irrigant type and temperature (P < 0.001). …”
Get full text

Quality assessment of some specific drug products beyond expiration dates in Saudi Arabia by Haya Aljohar, Ghadah H. altoum, Shahad A. Alkarni, Modhi M. Alburaidi, Samiah Alhabardi

“…Using validated HPLC methods compliant with USP and BP guidelines, we analyzed the active pharmaceutical ingredient (API) content of these medications post-expiry. Our methodology involved collecting expired samples from public hospitals, which were stored under controlled conditions (protected from light and maintained at a consistent temperature between 15 °C and 30 °C), and conducting physical and chemical analyses to assess their stability. …”
Get full text

Effectiveness of Remote High-Intensity Aerobic Interval Training on Quality of Life and Physical Health in Breast Cancer Survivors: Two Years Follow-Up by Aija Klavina PhD, Sintija Liepina MS, Maija Viskinte, Edgars Bernans PhD

“…This study aimed to evaluate the long-term effects of a remotely supervised HIIT program implemented during six months NACT on quality of life (QoL) and physical health outcomes in women with breast cancer, assessed 18–24 months post-intervention. The HIIT intervention study was two arm randomized control trial implementing remotely supervised 4x4 min training at an intensity of 85-95% of peak heart rate for 6 months during NACT. …”
Get full text

PCR method application to assess the molecular markers of intestinal barrier integrity in farming broilers by S. A. Shatalov, M. Kirici

“…The maintenance of intestinal health in broiler chickens is one most critic task to take the farming profitability in post-antibiotic era. Feed additives contained the blend of fatty acids and glycerides are proposed as a promising alternative to growth promoters and antimicrobial tool. …”
Get full text

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and gut microbiota composition: what do we know? by Veronica Maria Tagi, Veronica Maria Tagi, Martina Tosi, Martina Tosi, Ilenia Pia Greco, Eliana Stucchi, Elvira Verduci, Elvira Verduci, Gianvincenzo Zuccotti, Gianvincenzo Zuccotti

“…Post-streptococcal autoimmune neuropsychiatric disorders (PANDAS) are a group of pathological condition characterized by sudden-onset obsessive-compulsive and tic disorders following beta-hemolytic Streptococcus group A (GAS) infection, hypothesized to be caused by autoimmune mechanisms targeting the basal ganglia. …”
Get full text

Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer by Shenglan He, Jianmei Ji, Kaisi Zhu, Youlan Chen, Xiaowen Xu

“…Mice were treated with SB, and tumor burden was assessed by colon length. CAFs were isolated post-treatment for transcriptomic analysis to identify differentially expressed genes, with molecular docking providing in silico evidence of SB’s binding to target proteins. …”
Get full text

Outcomes of remnant‐preserving anterior cruciate ligament reconstruction using Achilles tendon allografts: A retrospective analysis of tibial tunnel widening and complications by Siyeon Kim, Dae Keun Suh, Dong Won Suh

“…Magnetic resonance imaging (MRI) scans were taken post‐operatively and at follow‐up, with tunnel width measured at both time points. …”
Get full text

Harnessing Salmonella as a potent vaccine delivery platform: Targeted HA/NA epitope presentation via alphavirus RdRp-driven expression to boost immune efficacy by Jun Kwon, Amal Senevirathne, John Hwa Lee

“…Notably, antibody subclass profiling indicated a Th1-skewed response beyond 21 days post-infection. Assessment of long-term immunity confirmed that even 42 days after booster vaccination could successfully respond to vaccinated antigens, elucidating the effectiveness of the Salmonella system. …”
Get full text

A data-driven framework for enhancing coastal flood resilience in resource-crunched developing nations by Aishwarya Narendr, Bharath Haridas Aithal, Sutapa Das

“…Finally, a data-driven probabilistic damage model is applied to estimate the built-up area damage for a 100-year coastal flood event (SSP-2.6). The pre-and post-adaptation damage estimate demonstrates the efficacity of NBS (mangroves) in reducing coastal flood risk. …”
Get full text