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31401
Visibility, democratic public space and socially inclusive cities
Published 2020-02-01“…Visibility can be a valuable tool for ex-ante and ex-post evaluations of the democratic character of streets to inform designers, researchers and policy makers about the impact of the proposed or finished interventions. …”
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31402
A brief international screening tool for traumatic birth and childbirth-related PTSD: the city BiTS-short form
Published 2025-08-01“…Introduction Screening to identify traumatic births and childbirth-related post-traumatic stress disorder (CB-PTSD) is critical for reducing the global burden of maternal mental health challenges. …”
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31403
Implementing routine assessment of perinatal anxiety: case studies
Published 2025-05-01“…Interviews and focus groups were conducted with the same participants post implementation. Data were analysed using framework analysis and a combined inductive-deductive approach. …”
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31404
Advancing the application of remote sensing for forest information needs in Canada: Lessons learned from a national collaboration of university, industrial and government stakehold...
Published 2021-06-01“…The project supported 24 post-doctoral fellows, PhD and MSc students that examined the roles that advanced three-dimensional remote sensing technologies can play in the development of accurate forest inventory systems across Canada. …”
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31405
Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes
Published 2025-07-01“…Methods We performed reduced representation bisulfite sequencing of matched pairs of post-mortem tissue from frontal cortex (FCX) and cerebellum (CER) from pathologically confirmed FTLD patients with TDP-43 pathology (FTLD-TDP) further divided into five subtypes and including both sporadic and genetic forms (N = 25 pairs per group), and neuropathologically normal controls (N = 42 pairs). …”
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31406
The Journey to Advanced Clinical Pharmacy Practice: Global Collaboration Will Accelerate the Pace
Published 2021-12-01“…To support the movement, schools of pharmacy adopted the Doctor of Pharmacy curriculum, and the hospitals dramatically increased the number of post-graduate residency programs.</p><p>Significant practice changed was underway, but it became clear the “practice model” utilized in health system pharmacy would need to change for pharmacists to realize their full potential in providing direct patient care. …”
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31407
Interactions between gut microbiota, plasma metabolome and brain function in the setting of a HIV cure trial
Published 2025-08-01“…Here, we analyzed longitudinal gut microbiome, plasma metabolome and brain functioning data to identify potential associations and novel putative biomarkers of HIV-associated neurocognitive disorders (HAND).MethodsData from fecal shotgun metagenomics, plasma metabolome, cognitive (standardized neuropsychological test score covering 6 cognitive domains, NPZ-6), functional (neuropsychiatric symptoms) and neuroimaging assessments were obtained and evaluated in 18 participants before and after RMD administration, and at the study end (post-MAP follow-up) in the BCN02 trial.ResultsParticipants with neurocognitive impairment (Lower vs. …”
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31408
WTAP/YTHDF1-mediated m6A modification amplifies IFN-γ-induced immunosuppressive properties of human MSCs
Published 2025-05-01“…Additionally, the stabilization of WTAP post-transcriptionally increased the mRNA expression of immunosuppressive molecules (IDO1, PD-L1, ICAM1, and VCAM1) in an m6A-YTHDF1-dependent manner; this effect further impacted the immunosuppressive capacity of IFN-γ licensing MSCs on activated T cells. …”
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31409
Evolution of the activities of states as reflected in legal and political Teachings
Published 2020-12-01“…The activities of such institutions established numerously in the post-war period are of increasingly administrative nature in cases when such organizations are vested with authoritative, supervisory or other similar powers whilst the specific features of national legal order are ignored. …”
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31410
Downregulation of forkhead box O1 (FOXO1) acetylation ameliorates cognitive dysfunction by inhibiting endoplasmic reticulum stress‐regulated neuronal apoptosis in APP/PS1 transgeni...
Published 2025-06-01“…In addition, one‐way analysis of variance was conducted for behavioral assessments and other tests involving four distinct groups, followed by a Tukey's honestly significant difference test for post hoc pairwise comparisons. Results The expression of SIRT1 was downregulated (in animal experiments, WT mice vs. …”
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31411
Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway
Published 2025-07-01“…Through biological techniques such as transcriptomics, CUT&Tag, and analysis of post-translational protein modifications, the molecular mechanisms underlying NA mediated ovarian inflammation were further elucidated based on models utilizing ovarian granulosa cells from pigs, humans, and mice. …”
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31412
Evaluating COVID-19 vaccine effectiveness during pre-Delta, Delta and Omicron dominant periods among pregnant people in the USA: Retrospective cohort analysis from a nationally sam...
Published 2024-06-01“…Objectives To evaluate the effectiveness of COVID-19 vaccinations (initial and booster) during pre-Delta, Delta and Omicron dominant periods among pregnant people via (1) COVID-19 incident and severe infections among pregnant people who were vaccinated versus unvaccinated and (2) post-COVID-19 vaccination breakthrough infections and severe infections among vaccinated females who were pregnant versus non-pregnant.Design Retrospective cohort study using nationally sampled electronic health records data from the National COVID Cohort Collaborative, 10 December 2020 –7 June 2022.Participants Cohort 1 included pregnant people (15–55 years) and cohort 2 included vaccinated females of reproductive age (15–55 years).Exposures (1) COVID-19 vaccination and (2) pregnancy.Main outcome measures Adjusted HRs (aHRs) for COVID-19 incident or breakthrough infections and severe infections (ie, COVID-19 infections with related hospitalisations).Results In cohort 1, 301 107 pregnant people were included. …”
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31413
UNCOVER: 404 Error—Models Not Found for the Triply Imaged Little Red Dot A2744-QSO1
Published 2025-01-01“…Our fiducial model decomposes the spectrum into a post-starburst galaxy dominating the UV-optical continuum and a reddened AGN being subdominant at all wavelengths and contributing at a level of ∼20%. …”
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31414
CLASSY. XI. Tracing Neutral Gas Properties Using UV Absorption Lines and 21 cm Observations
Published 2024-01-01“…We also present 21 cm H i observations for 35 galaxies, multiple of which are gas-poor or nondetected, possibly indicating the onset of a post-starburst phase. We find that our simultaneous one-component Voigt profile fits are capable of accurately modeling the LIS absorption for ∼75% of galaxies, mitigating challenges associated with saturation, infilling, and degeneracies. …”
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31415
Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19
Published 2025-05-01“…Here, we established protein signatures to define severe outcomes of acute COVID-19 and determined whether unique protein signatures during the first week of acute illness predict the risk of post-acute sequelae of COVID-19 (Long COVID) in a low-income country (LIC) setting.MethodUsing the Olink inflammatory panel, we measured the abundance of 92 proteins in the plasma of COVID-19 patients (n=55) and non-COVID-19 individuals (n=23). …”
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31416
Immune Durability and Breakthrough Infections 15 Months After SARS-CoV-2 Boosters in People over 65: The IMMERSION Study
Published 2025-07-01“…<b>Methods</b>: Immune responses were evaluated at 3, 9, and 15 months post-booster, measuring SARS-CoV-2-specific IgG antibodies against spike [IgG(S)] and nucleocapsid [IgG(N)] proteins, neutralizing activity against the Omicron BA.2 variant, and cellular immunity. …”
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31417
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31418
Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery
Published 2025-08-01“…Specifically, CLTC, CCT2, ANXA6, and HSPA8 are uniquely upregulated proteins in Cis‐sEV, and CLTC and ANXA6 are exclusively co‐localized in hair cells (HCs) post‐cisplatin exposure, suggesting that Cis‐sEV originate primarily from damaged HCs. …”
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31419
Global ground-based tropospheric ozone measurements: reference data and individual site trends (2000–2022) from the TOAR-II/HEGIFTOM project
Published 2025-07-01“…The findings are that (1) median TrOC trends computed with QR and MLR trends are essentially the same; (2) pole-to-pole, across all longitudes, TrOC trends fall within <span class="inline-formula">+</span>3 to <span class="inline-formula">−</span>3 ppbv per decade, equivalent to (<span class="inline-formula">−</span>4 % to <span class="inline-formula">+</span>8 %) per decade depending on site; (3) the greatest fractional increases occur over most tropical and subtropical sites, with decreases at northern high latitudes, but these patterns are not uniform; (4) post-COVID trends are smaller than pre-COVID trends for Northern Hemisphere mid-latitude sites. …”
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31420
The Impact of Mechanical Power Normalized to Predicted Body Weight on Outcomes in Pediatric ARDSTake-Home Points
Published 2025-09-01“…Study Design and Methods: This post hoc causal mediation analysis of data from a before-and-after study recruited children with PARDS from 21 PICUs. …”
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