Genome-wide identification of sugarcane HAT gene family and functional analysis of ScHAT1 in stress response by Shijiang Cui, Shiwei Yang, Ping Zhao, Shoujian Zang, Zhenxiang Li, Peixia Lin, Wanying Zhao, Yuanyuan Zhang, Dongjiao Wang, Youxiong Que, Qibin Wu

“…Its expression was significantly upregulated in the smut-susceptible ROC22 variety post smut pathogen infection. Additionally, ScHAT1 gene conferred enhanced tolerance to salt and drought stress. …”
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The role of glycerophospholipid metabolism in feline parvovirus infected CRFK cells by Zhen Sun, Zhen Sun, Zhen Sun, Zhen Sun, Hongwei Zhu, Hongwei Zhu, Hongwei Zhu, Hongwei Zhu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Jianlong Zhang, Jianlong Zhang, Jianlong Zhang, Jianlong Zhang, Linlin Jiang, Linlin Jiang, Linlin Jiang, Linlin Jiang, Xin Yu, Xin Yu, Xin Yu, Xin Yu, Jiayu Yu, Jiayu Yu, Jiayu Yu, Jiayu Yu, Xingxiao Zhang, Xingxiao Zhang, Xingxiao Zhang, Xingxiao Zhang

“…Untargeted metabolomics analyzed metabolic changes at 12 h, 24 h, and 48 h post-infection (hpi). Key pathways were validated through enzyme activity inhibition (Meclizine targeting PCYT2) and gene silencing (siRNA targeting PLPP1 and LPIN3).ResultsMetabolomics revealed the most significant differences at 48 hpi, identifying six significantly altered glycerophospholipid metabolites. …”
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Efficacy of LaAg Vaccine Associated with Saponin Against <i>Leishmania amazonensis</i> Infection by Mirian França de Mello, Patrícia de Almeida Machado, Pollyanna Stephanie Gomes, Gabriel Oliveira-Silva, Monique Pacheco Duarte Carneiro, Tadeu Diniz Ramos, Juliana Elena Silveira Pratti, Raquel Peralva, Luan Firmino-Cruz, Alda Maria Da-Cruz, Luciana Covre, Daniel Claúdio Oliveira Gomes, Bartira Rossi-Bergmann, Eduardo Fonseca Pinto, Alessandra Marcia da Fonseca-Martins, Herbert Leonel de Matos Guedes

“…SAP enhanced the immunogenicity of LaAg, as evidenced by increased IFN-γ-producing CD4⁺ and CD8⁺ T cells in the draining lymph nodes at 18 h post-challenge. Additionally, SAP facilitated the recruitment of lymphocytes, macrophages, neutrophils and eosinophils to the infection site. …”
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First result of boronization assisted by the ICWC on EAST with full metal wall by Y.H. Guan, G.Z. Zuo, W. Xu, Y.W. Yu, Z. Sun, Z. Wang, R. Ding, L. Zhang, T. Zhang, Z.W. Wu, S.T. Mao, H.L. Zhao, T.Q. Jia, S.A. Puyang, L. Wang, T. Wauters, X.Z. Gong, J.S. Hu

“…After one time 12 g boronization, it was found the thickness of B film was approximately 120 nm. Post-boronization observations indicated that substantial hydrogen (H) release during initial plasma discharges compared with the consumed W/B wall, attributed to H co-deposition during the ICWC-boronization processing, which led to uncontrollable divertor neutral pressure and plasma density. …”
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A standards-based application for improving platelet transfusion workflow by William Gordon, Maria Aguad, Layne Ainsworth, Samuel Aronson, Jane Baronas, Edward Comeau, Rory De La Paz, Justin B.L. Halls, Vincent T. Ho, Michael Oates, Adam Landman, Wen Lu, Shawn N. Murphy, Fei Wang, Indira Guleria, Sean R. Stowell, Melissa Y. Yeung, Edgar L. Milford, Richard M. Kaufman, William J. Lane

“…We looked at application usage over time and developed a multivariable logistic regression model to compute odds ratios that a patient undergoing HSCT would have a complicated thrombocytopenia course, with several model covariates including pre-/post-application deployment. Results: Usage of the application has been consistent since launch, with a slight dip during the first COVID wave. …”
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Anesthesia of Baryancistrus xanthellus (Siluriformes: Loricariidae): Bioassays with exposure and re-exposure cause reverse tolerance to eugenol by T.P. Nascimento, F.J.T. Barros, O.L.P. Couto, M.D.R. Paz, S.V.N. Junior, L.M. Sousa, T.S. Pereira

“…No mortality occurred within 72 hours post-anesthesia in any group, indicating low short-term toxicity. …”
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Preparation and Adsorption Performance of Polyacrylamide/<italic>Nicandra Physalodes </italic>(L.) <italic>Gaertn</italic> Composite Material for Congo Red Removal by GUO Wanjin, SUN Hao, CAO Chuqing, ZHAO Lijun

“…Therefore, it is imperative to explore the development of an efficient, non-polluting, and convenient post-treatment adsorbent for Congo red in wastewater.MethodsA composite adsorbent was created using <italic>Nicandra physalodes </italic>(L.) …”
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Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets by Marina Papaiakovou, Andrea Waeschenbach, Olumide Ajibola, Sitara SR Ajjampur, Roy M. Anderson, Robin Bailey, Jade Benjamin-Chung, Maria Cambra-Pellejà, Nicolas R. Caro, David Chaima, Rubén O. Cimino, Piet Cools, Anélsio Cossa, Julia Dunn, Sean Galagan, Javier Gandasegui, Berta Grau-Pujol, Emma L. Houlder, Moudachirou Ibikounlé, Timothy P. Jenkins, Khumbo Kalua, Eyrun F. Kjetland, Alejandro J. Krolewiecki, Bruno Levecke, Adrian JF Luty, Andrew S. MacDonald, Inácio Mandomando, Malathi Manuel, Maria Martínez-Valladares, Rojelio Mejia, Zeleke Mekonnen, Augusto Messa, Harriet Mpairwe, Osvaldo Muchisse, Jose Muñoz, Pauline Mwinzi, Valdemiro Novela, Maurice R. Odiere, Charfudin Sacoor, Judd L. Walson, Steven A. Williams, Stefan Witek-McManus, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle

“…STH control relies on microscopy-based diagnostics to monitor parasite prevalence and enable post-treatment surveillance; however, molecular diagnostics are rapidly being developed due to increased sensitivity, particularly in low-STH-prevalence settings. …”
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Surgical field contamination analysis in various artificial joint arthroplasties by Akihito Oya, Noboru Matsumura, Atsuhiro Fujie, Shu Kobayashi, Kengo Harato, Kazuya Kaneda, Tatsuaki Matsumoto, Mitsuru Yagi, Taku Suzuki, Robert Nakayama, Morio Matsumoto, Masaya Nakamura

“…Results: No early PJIs or bacterial growth was observed post-surgery. However, bacterial contamination was detected in 7 cases (4.7%), primarily in surgical trays. …”
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MiR‐146a engineered extracellular vesicles derived from mesenchymal stromal cells more potently attenuate ischaemia–reperfusion injury in lung transplantation by Xiucheng Yang, Shanchao Hong, Tao Yan, Mingzhao Liu, Mingyao Liu, Jin Zhao, Bingqing Yue, Di Wu, Jingbo Shao, Man Huang, Jingyu Chen

“…This innovative approach presents a promising strategy for enhancing donor lung preservation and improving post‐transplant outcomes in LTx. Highlights Nebulized Delivery of miR‐146a Engineered hucMSC‐EVs Mitigates Ischemia‐Reperfusion Injury (IRI) in Lung Transplantation. …”
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Guideline‐directed medical therapy implementation during hospitalization for cardiogenic shock by Matthew G. Dimond, Carolyn M. Rosner, Seiyon Ben Lee, Unique Shakoor, Taraneh Samadani, Wayne B. Batchelor, Abdulla A. Damluji, Shashank S. Desai, Kelly C. Epps, M. Casey Flanagan, Hala Moukhachen, Anika Raja, Matthew W. Sherwood, Ramesh Singh, Palak Shah, Daniel Tang, Behnam N. Tehrani, Alexander G. Truesdell, Karl D. Young, Mona Fiuzat, Christopher M. O'Connor, Shashank S. Sinha, Mitchell A. Psotka

“…These findings highlight an urgent need to augment multidisciplinary efforts to enhance the post‐discharge medical management and outcomes of patients who survive CS with HFrEF.…”
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Longitudinal Tracking of ALK-Rearranged NSCLC From Plasma Using Circulating Tumor RNA and Circulating Tumor DNA by Simon Heeke, PhD, Saumil Gandhi, MD, PhD, Hai T. Tran, PharmD, Vincent K. Lam, MD, Lauren A. Byers, MD, Don L. Gibbons, MD, PhD, Carl M. Gay, MD, PhD, Mehmet Altan, MD, Mara B. Antonoff, MD, FACS, Xiuning Le, MD, PhD, Janet Tu, MD, Maliazurina B. Saad, PhD, Michelle Pek, PhD, Jonathan Poh, PhD, Kao Chin Ngeow, DPhil, Anne Tsao, MD, MBA, FACHE, Tina Cascone, MD, PhD, Marcelo V. Negrao, MD, Jia Wu, PhD, George R. Blumenschein, Jr., MD, John V. Heymach, MD, PhD, Yasir Y. Elamin, MD

“…ALK rearrangements were detected in two patients pre-LCT, exclusively in ctRNA, but cleared completely post-LCT. The detection of ALK fusion at baseline was associated with significantly worse progression-free survival (p = 0.033). …”
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THE SOUTHERN FRAGMENT OF THE SIBERIAN CRATON: “LANDSCAPE” HISTORY OVER TWO BILLION YEARS by Arkady M. Stanevich, Irina M. Mashchuk, Anatoly M. Mazukabzov, Anatoly A. Postnikov, Tatiana A. Kornilova

“…Research results on sediments, bio-stratigraphy and geodynamics of the southern fragment of the Siberian craton (SSC, Fig. 2) provide for more or less reliable assessments of the status and evolution of ancient landscapes and biotas from the Lower Proterozoic to the Cenozoic.In the Lower Proterozoic, the geodynamic regime of the Urik-Iyskiy graben was similar to those of the westernpacific island-arc systems, which resulted in the orogen formation and established post-orogen granitoids of 1.86 bln years of age. …”
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Níveis de ruído em Unidade Terapia Intensiva Neonatal antes e após intervenção educativa [Noise levels in a Neonatal Intensive Care Unit before and after an educational interventio... by Vitória Eugenia Martins, Maria Paula Custódio Silva, Camila dos Santos Machado, Cinthia Lorena Silva Barbosa Teixeira, Divanice Contim, Jesislei Bonolo do Amaral Rocha

“…Data were collected in three stages – pre-intervention noise measurement, educational intervention, and post-intervention noise measurement – and were examined by descriptive analysis. …”
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In-depth assessment of BRAF, NRAS, KRAS, EGFR, and PIK3CA mutations on cell-free DNA in the blood of melanoma patients receiving immune checkpoint inhibition by Isabel Heidrich, Charlotte Rautmann, Cedric Ly, Robin Khatri, Julian Kött, Glenn Geidel, Alessandra Rünger, Antje Andreas, Inga Hansen-Abeck, Finn Abeck, Anne Menz, Stefan Bonn, Stefan W. Schneider, Daniel J. Smit, Christoffer Gebhardt, Klaus Pantel

“…Persistent or re-emerging ctDNA positivity post-therapy correlated with shorter progression-free survival (PFS, p = 0.003), while ctDNA-negative patients showed significantly improved outcomes. …”
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Prevalence and correlates of anxiety disorders and depressive disorders among older adults with non-communicable diseases: results from China Mental Health Survey by Hongmin Ge, Zhaorui Liu, Yue Tong, Yueqin Huang, Xiaofei Hou, Minghui Li, Yongping Yan, Shuiyuan Xiao, Lingjiang Li, Tingting Zhang, Jie Yan, Yaqin Yu, Xiufeng Xu, Zhizhong Wang, Yifeng Xu, Tao Li, Xiangdong Xu, Limin Wang, Huifang Yin, Guangming Xu

“…Data were weighted by age, sex, and residential distribution from the 2010 Chinese census to correct for selection probabilities and response rates, and were post-stratified for national representativeness. …”
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The behavioral ecology and breeding biology of the andean sparrow, Zonotrichia Capensis The behavioral ecology and breeding biology of the andean sparrow, Zonotrichia Capensis by Miller Alden H., Miller Virginia D.

“…</span><span style="font-size: 12.0pt; font-family: ";Arial";,";sans-serif";;">Dos y probablemente hasta tres jóvenes pueden ser alimentados fácilmente en el nido mientras permanecen en él, pero depredaciones o alguna otra limitación en el cuidado paternal (y no deficiencia en la alimentación proporcionada en la etapa post-nidal) parecen ser los principales factores negativos respecto a una mayor producción de individuos. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…For instance, the increase in computer use, shift to non-traditional workspaces (eg, home offices), and reduced physical activity among office workers often result in prolonged static postures and repetitive movements, factors that elevate the risk of negative health outcomes (10). These post-pandemic trends are also linked to a rise in mental health issues such as stress, burnout, and social isolation (11). …”
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A nationwide analysis of resource utilization and safety in patients undergoing mitral transcatheter edge-to-edge repair by Tharusan Thevathasan, Sophie Berlinghof, Daniel Elschenbroich, Julia M. Wiedenhofer, Sêhnou Degbeon, Luise Holzhauser, Fabian Barbieri, Mario Kasner, Anna Brand, Henryk Dreger, Steffen Desch, Ulf Landmesser, Markus Reinthaler, Carsten Skurk

“…Secondary outcomes (safety) were in-hospital mortality and post-procedural complications. Results: A total of 5,212 adults underwent mitral TEER. …”
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Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): a 12-month longitu... by Camila Amormino Corsini, Guilherme Rodrigues Fernandes Campos, Priscila Fernanda da Silva Martins, Priscilla Soares Filgueiras, Ana Esther de Souza Lima, Sarah Vieira Contin Gomes, Caroline De Almeida Leitao Curimbaba, Daniela Aparecida Lorencini, Eolo Morandi Junior, Victor Mattos da Silva, Maria Célia Cervi, Marcos de Carvalho Borges, Marcos de Carvalho Borges, Poliana Remundini de Lima, João Paulo Resende do Nascimento, Paulo Roberto Lopes Correa, Leda dos Reis Castilho, Jaquelline Germano de Oliveira, Olindo Assis Martins Filho, Maurício Lacerda Nogueira, Maurício Lacerda Nogueira, Maurício Lacerda Nogueira, Immunita team, Rafaella Fortini Queiroz e Grenfell, Rafaella Fortini Queiroz e Grenfell, Rafaella Fortini Queiroz e Grenfell, Ana Clara Almeida, Daniel Alvim Pena de Miranda, Isabela Camargos, Raquel Amorim, Érica Louback de Oliveira, Clara Raíssa do Prado Pêgo, Viviane Cristina Fernandes dos Santos

“…No significant differences in neutralization between BA.1 and BA.5 were observed post-vaccination, contrary to prior literature, suggesting uniform effectiveness against these subvariants.DiscussionThis study demonstrates that CoronaVac significantly enhances and sustains neutralizing antibody titers in children and adolescents for up to one year, including against immune-evading subvariants like BA.5. …”
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