Comparative Effectiveness of Different Frequencies of Spinal Cord Stimulation for the Treatment of Patients with Failed Back Surgery Syndrome: Systematic Review and Network Meta-An... by Qin YY, Zhang CP, Tang SS, Wu JP, Zhu LX, Li YH, Xu F

“…Yuan Yuan Qin,1,2,* Chun Pan Zhang,1,2,* Shun Song Tang,1,2 Jiang Ping Wu,1,2 Li Xuan Zhu,1,2 Yan Hua Li,1,2 Fei Xu1,2 1Department of Pain Management, The First People’s Hospital of Yunnan Province, Kunming, Yunnan, People’s Republic of China; 2The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fei Xu, Department of Pain Management, The First People’s Hospital of Yunnan Province, 157 Jinbi Road, Kunming, 650032, People’s Republic of China, Email 494428530@qq.comPurpose: Failed back surgery syndrome (FBSS) is a common and challenging complication after lumbar spine surgery, with around 30% of patients experiencing this condition post-surgery. Spinal cord stimulation (SCS) is a prevalent treatment for FBSS, yet there is a lack of systematic comparisons among different SCS frequencies. …”
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SURGICAL TACTICS REGARDING CEREBRAL METASTASES WITH HEMORRHAGES by E. V. Prozorenko, V. B. Karakhan, A. Kh. Bekyashev, V. A. Alyoshin, D. M. Belov, D. R. Naskhletashvili, N. V. Sevyan, A. A. Mitrofanov

“…The patients were distributed in accordance with the RPA (recursive partitioning analysis) classes: I class (n = 7), II class (n = 39), III class (n = 23); in accordance with the hemorrhage type: intratumoral type (26 metastases), perifocal type (20), mixed type (32); in accordance with the histological principle: melanoma (n = 25), lung cancer (n = 13), kidney cancer (n = 17), breast cancer (n = 4), colorectal cancer (n = 1), soft tissue sarcoma (n = 4), non-seminomatous germ cell tumor (n = 5).Results. Early post-surgical lethality comprised 6 % (n = 4). Development of local relapses comprised 16 % (n = 11). …”
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Changes in Blood Eosinophil Counts Predict the Death of Patients With Myocardial Infarction After Hospital Discharge by Kaiyang Lin, Manqing Luo, Xia Gu, Jun‐Yan Xu, Jinwei Tian, Peter Libby, Guo‐Ping Shi, Junli Guo

“…Dynamic changes of blood eosinophil counts offer a more accurate prediction of post‐myocardial infarction deaths than a single time point data analysis.…”
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Non-inferiority comparison of medical glue and hook-wire for preoperative localization of multiple pulmonary nodules by Zexin Xie, Zexin Xie, Ran Ma, Ran Ma, Tao Gao, Tao Gao, Jingsong Liu, Jingsong Liu, Kewei Zhang, Kewei Zhang, Jun Li, Jun Li, Xiaotong Zhou, Xiaotong Zhou, Hao Zhang, Hao Zhang

“…Furthermore, compared to hook-wire, medical glue was associated with a lower incidence of pneumothorax and pulmonary hemorrhage, as well as reduced pain scores at 2 h post-localization.Clinical Trial Registrationhttps://www.chictr.org.cn, identifier (ChiCTR2400080040).…”
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Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma by Bartimée Galvan, Loïc Ongena, Jonathan Bruyr, Gregory Fettweis, Eva Lucarelli, Arnaud Lavergne, Emeline Mariavelle, Tina M. O’Grady, Zahrat El Oula Hassoun, Margaux Claes, Laurence Dubois, Kevin A. W. Lee, Véronique Kruys, Cyril Gueydan, Jules Durand, Eric Hervouet, Florian H. Geyer, Ana Banito, Roland Imle, Lianghao Mao, Ashok K. Jayavelu, Thomas G. P. Grünewald, Florencia Cidre-Aranaz, Jean-Claude Twizere, Franck Dequiedt

“…Our findings uncover a post-transcriptional function of EWSR1::FLI1 and suggest that targeting mRNA stability mechanisms may offer therapeutic opportunities for EwS.…”
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Pattern and determinants of self-medication among pregnant women attending antenatal clinics in primary health care facilities in Ogbomoso, Oyo State, Nigeria by Olaniyan Akintunde Babatunde, Ikeola Adejoke Adeoye, Aishat Bukola Usman, Chukwuma David Umeokonkwo, Olufunmilayo Ibitola Fawole

“…Conclusion: The prevalence of self-medication was high and was more pronounced among married, urban dwellers and those with post-basic education including the respondents aged 25 years and above. …”
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Improved functional outcomes and cost benefits of door-to-needle time under 30 min in acute ischemic stroke: an observational study by Jia Dong James Wang, Ying-Qiu Dong, Joshua Y. P. Yeo, Kevin Soon Hwee Teo, Shiyang Ng, Mingxue Jing, Bernard P. L. Chan, Leonard L. L. Yeo, Magdalene L. J. Chia, Louis Widjaja, Lily Y. H. Wong, Pamela Lim, Shikha Kumari, Diarmuid Murphy, Hock-Luen Teoh, Benjamin Y. Q. Tan

“…Multivariate linear and logistic regressions were performed to evaluate impact of DTN time on functional and financial outcomes, including modified Rankin's Score (mRS) at 3-months post-AIS, length-of-stay (LoS), total hospitalization cost, symptomatic intracerebral hemorrhage (SICH) and inpatient mortality.Results1,146 patients (62.0% male) with mean age of 68.6 years were included. …”
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Results of a study of the effectiveness of direct coronary oxygen persufflation as a donor heart conditioning method by M. O. Zhulkov, D. A. Sirota, I. S. Zykov, A. K. Sabetov, K. A. Agaeva, А. G. Makaev, D. M. Osintsev, A. P. Nadeev, V. Е. Kliver, E. E. Kliver, A. M. Volkov, A. R. Tarkova, А. V. Fomichev, A. M. Chernyavsky

“…After 3 hours of donor heart preservation, orthotopic heart transplantation (OHTx) was performed. In the post-transplant period, we studied central hemodynamic parameters, myocardial oxygen consumption, level of myocardial ischemia markers (troponin I, TnI; creatine phosphokinase-MB, CPKMB; lactate dehydrogenase, LDH), and histological signs of structural cellular injury. …”
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NIPT of Maternal Plasma-Originated cfDNA: Applications and Guide for the Implementation by Fernández Martínez FJ, Gil Mira MM, González González C, Madrigal Bajo I, Oancea Ionescu R, Orellana Alonso C

“…It addresses key aspects such as technical and analytical requirements, integration with invasive diagnostic methods, pre- and post-test genetic counseling, and legal considerations. …”
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Finite element model-based evaluation of the effectiveness of the incisional skinbridge procedure for posterior horseshoe perianal abscess by Shi Rong, Wang Jing, Ke Minhui, Chen Zuqing, Huang Juan, Chen Riqi, Wang Zhaochu

“…Six pivotal nodes were selected for model validation, followed by comparisons of displacement disparities between the two models and an evaluation of anal pressure three months post-surgery. [Results] Displacements measured surgically at 174 nodes in the standard skin-bridge group and 173 nodes in the wide skin-bridge group significantly deviated from the model prediction (P<0.05), whereas other nodes displacements measured surgically aligned with the model (P>0.05). …”
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Long Term Outcomes of Anti-COVID-19 Vaccines in Patients with Systemic Lupus Erythematosus: A Multicentre Study by Giovanni Benanti, Giuseppe A. Ramirez, Tommaso Schioppo, Lorenza Maria Argolini, Gabriella Moroni, Grazia Bonelli, Renato Alberto Sinico, Federico Alberici, Federica Mescia, Luca Moroni, Gabriele D. Gallina, Biancamaria Venerandi, Francesco Tamborini, Chiara Bellocchi, Lorenzo Beretta, Roberto Caporali, Enrica Bozzolo, Lorenzo Dagna, Maria Gerosa

“…Limited data exist on the long-term impact of vaccination in patients with SLE. <b>Methods</b>: A post-vaccine group (PVG, <i>n</i> = 284) from a multicentric cohort of vaccinated patients with SLE from six tertiary referral centres in Northen Italy was compared with a control group (CG, <i>n</i> = 223) of similar demographics observed in the 2015–2019 period to investigate survival, hospitalisation, pregnancy, disease flare, disease progression, infection, and chronic complication accrual rates. …”
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Composted PBST Biodegradable Mulch Film Residues Enhance Crop Development: Insights into Microbial Community Assembly, Network Interactions, and Soil Metabolism by Liuliu Li, Liyuan Liu, Guoyuan Zou, Xuexia Wang, Li Xu, Yong Yang, Jinfeng Liu, Huabo Liu, Dongsheng Liu

“…These findings suggest that, although composting post-use BDM may reduce their negative ecological effects, possibly via accelerating the early breakdown of residues, the feasibility and scalability of this approach require further validation under real-world field conditions.…”
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Establishment of an Intestinal Fibrosis Model Associated with Inflammatory Bowel Disease in VDR-/- Mice Induced by Helicobacter hepaticus Infection and Mechanism Exploration by WU Zhihao, CAO Shuyang, ZHOU Zhengyu

“…Seven days after the final administration, the infection status of the mice was assessed, and their body weight was recorded weekly. At the 16th week post-infection, the mice were dissected, and the length of the colon tissue was measured, with fecal moisture content analyzed. …”
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Ecological drivers of malaria vector habitat and transmission over 1 year of long-lasting insecticidal net intervention in Côte d’Ivoire by Benoit Talbot, Ludovic P. Ahoua Alou, Alphonsine A. Koffi, Colette Sih, Edouard Dangbenon, Marius G. Zoh, Soromane Camara, Serge B. Assi, Raphael N’Guessan, Louisa A. Messenger, Natacha Protopopoff, Jackie Cook, Manisha A. Kulkarni

“…., and for P. falciparum-infected vectors, at baseline and 1-year post-LLIN intervention. We compared the projected habitat and habitat determinants for each species, and assessed the respective contributions of each intervention arm and environmental factors on the probability of species occurrence. …”
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Family protection motivation and economic vulnerability: a network analysis of public influenza risk perception, education and mitigation strategies in China by Cheng Yang, Cheng Yang, Jiawei Li, Jiawei Li, Xianqiong Feng, Xianqiong Feng, Shaoyu Su, Shaoyu Su, Qin Zeng, Qin Zeng

“…BackgroundIn the post-pandemic era, influenza and COVID-19 jointly exacerbate global public health burdens, yet persistent biases in risk perception drive declining vaccination rates and health disparities. …”
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Maternal β-carotene addition has long-term effects on intestinal health of offspring chicks by Taiping Wang, Taiping Wang, Da Wan, Da Wan, Tianyu Ren, Ye Tao, Ye Tao, Min Wu, Xin Zheng, Xin Zheng

“…Nevertheless, the extended impact of maternal β-carotene inclusion on the intestinal health of post-hatching chicks is still not fully elucidated.ObjectiveThis research aimed to evaluate the impacts of maternal β-carotene supplementation on the intestinal development and microbial communities in chicks after hatching.MethodsA total of 1,215 Hy-Line Brown laying hens were divided into three groups, with each group containing five subgroups of 81 hens each. …”
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Lifetime co-exposure of parental zebrafish to benzophenone-3 and titanium dioxide nanoparticles leads to developmental neurotoxicity and thyroid endocrine disruption in their offsp... by Linxuan Tian, Chunlan Dai, Enfu Feng, Qinyuan Yang, Yao Jiang, Yubo Liu, Yanni Wang, Junyan Tao

“…Zebrafish embryos were exposed to environmentally relevant concentrations of BP3 (10 μg/L), nano-TiO2 (100 μg/L), and their combination from 6 hours post-fertilization (hpf) to 150 days. Results showed the presence of BP3 in the gonads of F0 and F1 embryos, with combined exposure alleviating BP3 accumulation. …”
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MAintAin Activity in Arthritis: A study protocol of the co-development and feasibility testing of a physical activity maintenance intervention [version 2; peer review: 2 approved] by David French, Deirdre Hurley Osing, Aisling Walsh, Suzanne McDonough, Aoife Stephenson, Kathleen Bennett, Noreena Coyle, Chloe Grimmett, Claire Kinneavy, Stacey Grealis, Helen French, Oliver Fitzgerald, Mick Thacker, Maria Stokes

“…Phase 4, Feasibility Study: The final phase is a pre-post, mixed methods feasibility evaluation of the newly developed multicomponent PA maintenance intervention for people living with arthritis, after completion of a physiotherapy led structured exercise programme. …”
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A Predictive Model of Cardiovascular Aging by Clinical and Immunological Markers Using Machine Learning by Madina Suleimenova, Kuat Abzaliyev, Madina Mansurova, Symbat Abzaliyeva, Almagul Kurmanova, Guzel Tokhtakulinova, Akbota Bugibayeva, Diana Sundetova, Merei Abdykassymova, Ulzhas Sagalbayeva, Raushan Bitemirova, Zhadyra Yerkin

“…CD14+ shows a moderate positive correlation with post-infarction cardiosclerosis, accounting for 37%. …”
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Malignant Bowel Obstruction in Ovarian Cancer Recurrence: The Role of Palliative Surgery in a Decision-Making Process by Eugenia De Crescenzo, Marianna Fontana, Giulia Dondi, Stefano Friso, Alessandro Bovicelli, Marco Di Stanislao, Marco Tesei, Alessandra De Palma, Pasquale Chieco, Matteo Rottoli, Paolo Bernante, Gloria Ravegnini, Anna Myriam Perrone, Pierandrea De Iaco

“…Furthermore, after surgical treatment, five patients (55%) experienced postoperative complications; in four cases, severe anemia requiring blood transfusion, while one patient developed post-surgical sepsis, which evolved into multiple organ failure and death. …”
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