Investigation de l’effet de la Semantic Feature Analysis sur le manque du mot au stade débutant de la maladie d’Alzheimer : études de cas by Melike Semiz, Aurélie Miceli, Sandrine Basaglia-Pappas, Isabelle Simoes Loureiro

“…Les performances en dénomination ont été évaluées lors des phases pré-intervention, post-intervention et maintien à l’aide d’une tâche de dénomination conçue pour cette étude. …”
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Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapy by Yuwei Li, Maoxin Fang, Haotian Yu, Xianglei Wang, Shiyao Xue, Zeze Jiang, Zixuan Huang, Shaoqin Rong, Xiaoli Wei, Zhigang Lu, Min Luo

“…AECM@PC7A exhibits remarkable anti-tumor efficacy when compared to vaccines with diverse formulations, and demonstrates therapeutic potential in post-surgical and humanized xenograft tumor models. …”
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Targeting USP1 Potentiates Radiation‐Induced Type I IFN‐Dependent Antitumor Immunity by Enhancing Oligo‐Ubiquitinated SAR1A‐Mediated STING Trafficking and Activation by Weilin Zhou, Yuxuan Zhao, Wenjing Qin, Weijian Wu, Chenyang Liao, Yiqiu Zhang, Xingli Yang, Xue Chen, Youqiao Wang, Yushan Kang, Jiaxin Wu, Jiaojiao Zhao, Junmin Quan, Xuecen Wang, Xianzhang Bu, Xin Yue

“…Through chemical screening targeting deubiquitinating enzymes, we identified USP1 (Ubiquitin Specific Peptidase 1) inhibitor as an enhancer of post‐radiotherapy dsDNA responses. Mechanistically, within the context of immune‐stimulatory cells in TME, USP1 serves as a suppressor in the stress‐mediated stages of the cGAS (Cyclic GMP‐AMP synthase) ‐STING (Stimulator of interferon genes protein) signaling pathway, specifically affecting the trafficking of STING from endoplasmic reticulum to Golgi apparatus. …”
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Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice by Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon

“…Testes were removed from all mice, and histomorphometry and flow cytometry analyses were performed 60 days post-treatment. Additionally, protein structure extraction, protein-protein docking analysis, and data visualization were conducted.Results: Histomorphometry and flow cytometry showed that most seminiferous tubules in the therapy groups exhibit­ed normal morphology and restored spermatogenesis, unlike the azoospermia group. …”
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A multi-centred pilot randomised controlled trial of learning through play plus culturally adapted cognitive behaviour therapy for treating postnatal depression in Nigerian women by Dung Ezekiel Jidong, Dung Ezekiel Jidong, Tarela Juliet Ike, Maigari Yusuf Taru, Juliet Yop Pwajok, Charles Nnaemeka Nwoga, John Ezekiel Jidong, Christopher Francis, Shadrack Bitrus Mwankon, Karick Haruna, Zubairu Dagona, Nusrat Husain, Nusrat Husain

“…Data were collected at various time points (baseline, end of intervention and 3 months post-enrolment) and analysed using appropriate descriptive and inferential statistics. …”
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Derivation and internal–external validation of clinical prediction model for postoperative clinically important hypotension in patients undergoing noncardiac surgery: an internatio... by Stephen Su Yang, German Malaga, Maria Lazo-Porras, Patricia Busta-Flores, Aida del Carmen Rotta-Rotta, Pavel S. Roshanov, Daniel I. Sessler, Amal Bessissow, Thomas Schricker, Vicky Tagalakis, Diane Heels-Ansdell, Shirley Pettit, P.J. Devereaux

“…The postoperative period was defined from the Post-Anesthesia Care Unit to hospital discharge. …”
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Treadmill Training Increases SIRT-1 and PGC-1α Protein Levels and AMPK Phosphorylation in Quadriceps of Middle-Aged Rats in an Intensity-Dependent Manner by Nara R. C. Oliveira, Scherolin O. Marques, Thais F. Luciano, José R. Pauli, Leandro P. Moura, Erico Caperuto, Bruno L. S. Pieri, Julia Engelmann, Gisele Scaini, Emilio L. Streck, Fabio S. Lira, Ricardo A. Pinho, Eduardo R. Ropelle, Adelino S. R. Silva, Cláudio T. De Souza

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Clinical and Ultrasound Evaluation of Hemiplegic Shoulder Pain in Stroke Patients: A Longitudinal Observational Study Starting in the First Hours After Stroke by Filippo Cotellessa, William Campanella, Luca Puce, Maria Cesarina May, Marta Ponzano, Riccardo Picasso, Matteo Mordeglia, Davide Subbrero, Ester Cecchella, Laura Mori, Davide Sassos, Massimo Del Sette, Matteo Formica, Carlo Trompetto

“…This longitudinal study aimed to investigate the clinical and ultrasound characteristics of HSP emerging within the first 72 h (T0) post-stroke, with follow-ups at one month (T1) and three months (T2). …”
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Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation by Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu

“…The average percentage of elicited electrodes (eABR%) during the operation is 72.73±17.99%. Post‐activation, hearing and speech outcomes improved steadily. …”
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Analysis of failure mechanisms and behavior of LiCoO2-graphite batteries at 0 ℃ by Ke Li, Jia Niu, Yifan Hao, Jiaxin Yao, Pushpendra Kumar, Zhenhao Luo, Songtong Zhang, Jing Wang, Xiayu Zhu, Wenjie Meng, Jingyi Qiu, Guiling Wang, Hai Ming

“…Through the analysis of differential voltage and incremental capacity curves, along with post-mortem analysis after cycling, it is revealed that the desolvation energy of lithium largely determines whether lithium integrates into the active materials or plates on the electrode surface. …”
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Exploring Aneurysmal Bone Cysts of the Skull: Insights from a Review of the Literature and a Case Report by Flavio Panico, Leonardo Bradaschia, Pasquale Cardellicchio, Fabio Cofano, Enrico Lo Bue, Stefano Colonna, Alberto Morello, Andrea Bianconi, Diego Garbossa, Gianluca Piatelli, Marco Pavanello

“…Secondary lesions showed a higher frequency of complications within the first months post-surgery (<i>p</i> = 0.041). <b>Conclusions</b>: No significant correlation was found between ABCs and fibrous dysplasia (FD) or head trauma. …”
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Study protocol for assessing the effectiveness, implementation fidelity and uptake of attachment & child health (ATTACH™) Online: helping children vulnerable to early adversity by Nicole Letourneau, Lubna Anis, Cui Cui, Ian D. Graham, Kharah Ross, Kendra Nixon, Jan Reimer, Miranda Pilipchuk, Emily Wang, Simone Lalonde, Suzanna Varro, Maria Jose Santana, Ashley Stewart-Tufescu, Angela Soulsby, Barbara Tiedemann, Leslie Hill, Tiffany Beks, Martha Hart

“…Effectiveness outcomes examine children’s development and mental health, parent–child relationships, and RF, measured before, after, and 3 months post-intervention. Implementation outcomes include fidelity and uptake of ATTACH™ Online, assessed via tailored tools and qualitative interviews using NPT, with parents, health care professionals, and administrators from agencies. …”
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Surgical Antibiotic Prophylaxis Used in A University Clinics Hospital and Antibiotic Costs: A 3-year Survey by Vianney N. Ntabaza, PhD, Antonelle Pardo, PhD, Amandine Nachtergael, PhD, Julien Bamps, MSc, Salvius A. Bakari, PhD, Pierre Duez, PhD, Stephanie Patris, PhD, Byanga Kahumba, PhD

“…Background: Surgical Site Infections (SSIs) represent one of the most common post-operative complications and are the third most prevalent nosocomial infections. …”
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Diagnostic Effectiveness of Transforming Growth Factor Beta 1 in Assessing the Risk of Developing Graft Dysfunction in Liver Recipient Children by R. M. Kurabekova, O. M. Tsiroulnikova, I. E. Pashkova, A. G. Olefirenko, O. E. Gichkun, L. V. Makarova, R. A. Monakhov, P. O. Shevchenko

“…The TGF-β1 concentration in plasma was determined using ELISA on average 3 ± 2 days prior to liver transplantation and in the early post-transplant period.Results. The level of TGF-β1 in the blood of children with liver cirrhosis was lower than in healthy children (p = 0.001). …”
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The donor management algorithm in transplantation of a composite facial tissue allograft.. First experience in Russia by V. V. Uyba, K. K. Gubarev, S. E. Voskanyan, M. A. Volokh, V. L. Vinogradov, N. V. Kalakutskiy, G. G. Khubulava, A. I. Zakhlevnyy, I. Yu. Murashov, A. F. Lesnyakov, E. S. Romanova, V. A. Shcherbakov, V. V. Aleksandrov, A. S. Samoylov, M. V. Zabelin

“…Establishing of facial VCA transplantation Program is a complicated process for transplant centers and can hardly be implemented without a properly organized post-mortem organ donation system at a national level. …”
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Outcomes of Different Lifestyle Approaches in a Multicentre, Open-Label, Parallel-Group, Randomised Controlled Trial of the Effectiveness of Integrating a Pragmatic Pathway for Pre... by Werd Al-Najim, Babak Dehestani, Ahmed W. Al-Humadi, Danielle H. Bodicoat, Dimitris Papamargaritis, Michael Lean, Barbara McGowan, David R. Webb, John PH Wilding, Melanie J. Davies, Carel W. le Roux

“…<b>Background/Objectives:</b> The STRIVE study was a multicentre, open-label, real-world clinical trial evaluating the effectiveness of a targeted prescribing pathway for liraglutide 3.0 mg as an adjunct to standard care versus standard care alone in people with obesity attending Specialist Weight Management Services (SWMS) in the UK and Ireland. This post hoc analysis focuses on the standard care arm to explore differences in outcomes between sites, particularly the potential impact of offering meal replacements as part of usual care. …”
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Unraveling Genomic and Pathogenic Features of <i>Aeromonas ichthyocola</i> sp. nov., <i>Aeromonas mytilicola</i> sp. nov., and <i>Aeromonas mytilicola</i> subsp. <i>aquatica</i> su... by Nihed Ajmi, Muhammed Duman, Batuhan Coskun, Ceren Esen, Oner Sonmez, Gorkem Tasci, Orkide Coskuner-Weber, Hilal Ay, Digdem Yoyen-Ermis, Artun Yibar, Andrew P. Desbois, Izzet Burcin Saticioglu

“…Further genomic analyses identified biosynthetic gene clusters for nonribosomal peptides (NRPs) and ribosomally synthesized and post-translationally modified peptides (RiPPs), which often have roles in secondary metabolite production. …”
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Phase I first-in-human dose escalation study of the oral casein kinase 1α and cyclin dependent kinase 7/9 inhibitor BTX A51 in advanced MDS and AML by Brian J. Ball, Wenbin Xiao, Gautam Borthakur, Le Xuan Truong Nguyen, Melissa Valerio, Avanthika Venkatachalam, Guido Marcucci, Anthony S. Stein, Dung Luong Thai, David N. Cook, Kyle Chan, Sonali Persaud, Ross L. Levine, Omar Abdel-Wahab, Yinon Ben-Neriah, Eytan M. Stein

“…BTX A51 increased the expression of p53 and reduced the expression of MCL1 and RNA polymerase II phosphorylation in pre- and post-treatment immunocytochemistry studies. Overall, 3 patients (10%) experienced complete remission with incomplete count recovery (CRi). …”
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Longitudinal study on quality of life following cervical cancer treatment in Botswana by Natalie Taylor, Doreen Ramogola-Masire, Karen Canfell, Katharine A Rendle, Lesego Gabaitiri, Surbhi Grover, Nicola Zetola, Memory Bvochora-Nsingo, Sebathu Chiyapo, Dawn Balang, Lilie L Lin, Mark N Polizzotto, Erle Robertson, Salman Khan, Rohini K Bhatia, Shalini Vinod, Paseka Tladi

“…The European Organisation for Research and Treatment of Cancer Core Quality-of-Life (QLQ-C30) and cervical cancer-specific (QLQ-Cx24) questionnaires, translated into Setswana, were used to assess the QoL of patients prior to treatment (baseline), at the end of treatment (EOT) and in 3 month intervals post-treatment for 2 years, and statistical analyses were performed.Results A total of 294 women (median age: 46 years) were enrolled and followed up for an average of 16.4 months. …”
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Prediction of long-term major adverse cardiac events after myocardial infarction: value of combination of inflammatory biomarkers and GRACE score by Dan Tian, Nianxi Yu, Tianxiao Mao, Yanli Li, Ruiyan Liu, Ye Xu, Dong Huang, Qianzhou Lv, Kunming Pan, Kunming Pan

“…The primary endpoint was the post-MI occurrence of a composite of major adverse cardiovascular events (MACE), including cardiovascular death, non-fatal MI, and non-fatal ischemic stroke. …”
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