Highly Active Antiretroviral Therapy (HAART) - “Sulfonyl”, and anal cancer outcomes from patients living with HIV: a retrospective cohort by Raelson Rodrigues Miranda, Erika Andrade Rocha, Amanda Acioli de Almeida Robatto, Denis Artico Galhera, Carolina Ribeiro Victor, Karim Yaqub Imbrahim, Camila Motta Venchiarutti Moniz

“…The overall response rate at 6 months post-treatment was significantly higher in the sulfonyl-HAART group (100%) compared to the non-sulfonyl group (20/36; 55.6%), Odds Ratio (OR) 0.00, 95% CI: 0–0.72, p = 0.004). …”
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Lactylation and its roles in diseases: a systematic bibliometric exploration of the research landscape by Mengjia Li, Mengjia Li, Yuhang Liu, Chuhan Jiang, Shiyu Zhang, Mengyu Nan, Jiaxi Liu, Yangyang Han, Yangyang Han

“…BackgroundLactylation, a post-translational modification (PTM), has gained attention for its role in disease pathogenesis, particularly in cancer and immune regulation. …”
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Enhanced effect of radiofrequency ablation on HCC by siRNA-PD-L1-endostatin Co-expression plasmid delivered by Pengfei Chen, Kun Li, Jinwei Chen, He Hei, Jiaxin Geng, Nannan Huang, Mengyu Lei, Huijie Jia, Jianzhuang Ren, Chenwang Jin

“…The combination therapy significantly reduced tumor growth, angiogenesis, and PD-L1/VEGF expression in tumor tissues post-RFA. Additionally, it induced tumor cell apoptosis, inhibited proliferation and migration, and increased the infiltration of T lymphocytes, granzyme B+ T cells, and CD86+macrophages within tumors. …”
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The feasibility of conducting a randomized controlled trial that compares immediate versus optional delayed surgical repair for treatment of acute Anterior cruciate ligament injury... by Feryal Ghafelzadeh Ahwaz, Annemie Smeets, Stijn Bogaerts, Pieter Berger, Koen Peers

“…., rehabilitation with optional delayed surgery in case of persistent instability) or immediate surgery (< 12 weeks post-injury). The primary aim of this pilot study was to assess the feasibility of participant recruitment. …”
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Pattern and correlates of obesity among public service workers in Ondo State, Nigeria: a cross-sectional study by Isaac Aladeniyi, Oladele Vincent Adeniyi, Olufunmilayo Fawole, Mary Adeolu, Daniel Ter Goon, Anthony Idowu Ajayi, Eyitayo O Owolabi

“…In the bivariate analysis, female sex (p < 0.000), age above 41 years (p < 0.000), post-primary education level (p < 0.001), marriage (p < 0.000), no alcohol consumption (p < 0.001), diabetes (p < 0.000) as well as hypertension (p < 0.000) were significantly associated with obesity. …”
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ICT communication with family/friends and its associations with mental health and insomnia in COVID-19 patients during hospital quarantine: a cross-sectional study in Shenzhen, Chi... by Tie Cheng Liu, Zi Yuan Yu, Shi Wen Lin, Rui Heng Nong, Yi Na Lu, Chen Rui Wang, Jia Jing Zeng, Peng Fei Li, Li Jun Zhong, Shi Tong Xu, Wei Jie Gong

“…Using any or more types of ICT was associated with less depression, anxiety, post-traumatic, somatization symptoms, and insomnia (0.31–0.55 and 0.67–0.85, respectively, all P ≤ 0.001), especially using video calls (0.36–0.76, P ≤ 0.05). …”
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Acute kidney injury after myocardial infarction: prognostic implications via dual robust methods by Pan Guo, Fang Tao, Lili Du, Hongmei Yang, Wenguang Wang, Chunpeng Ma, Xile Bi, Lin Ren, Hongtao Yin, Lixiang Ma

“…The impact of KDIGO AKI staging on post-discharge short- and long-term outcomes, particularly early-stage AKI, is not well understood. …”
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NCT-CXR: Enhancing Pulmonary Abnormality Segmentation on Chest X-Rays Using Improved Coordinate Geometric Transformations by Abu Salam, Pulung Nurtantio Andono, Purwanto, Moch Arief Soeleman, Mohamad Sidiq, Farrikh Alzami, Ika Novita Dewi, Suryanti, Eko Adhi Pangarsa, Daniel Rizky, Budi Setiawan, Damai Santosa, Antonius Gunawan Santoso, Farid Che Ghazali, Eko Supriyanto

“…Non-parametric statistical testing (Kruskal–Wallis, H = 14.874, <i>p</i> = 0.0019) and post hoc Nemenyi analysis (<i>p</i> = 0.0138 and <i>p</i> = 0.0056) confirm the superiority of discrete-angle augmentation over mixed strategies. …”
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Impact of COVID-19 on healthcare programs in Zimbabwe: a mixed methods study by Nicholas Midzi, C. Haruzivishe, E. Gonese, S. Sembuche, M. J. Mutsaka-Makuvaza, R. Ayebare, T. Muwonge, S. Nakasendwa, C. Mateta, T. Madanhire, C. N. Chaibva, C. Gwatiringa, K. Mutsaka, I. Phiri, M. Abdulaziz, P. C. Kabwe, V. Dube-Mawerewere, R. Tajudeen, M. P. Fallah, M. Dobbie

“…Methods A mixed-methods study compared healthcare service delivery trends from the Ministry of Health and Child Care before, during and post the pandemic. It employed two methods of data collection: Key informant interviews (KII) and secondary data analysis from the Zimbabwe District Health Information Systems 2 (DHIS2). …”
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When Antlers Grow Abnormally: A Hidden Disease Behind Common Cervid Trophy Deformities, Introducing Pedunculitis Chronica Deformans by Farkas Sükösd, István Lakatos, Ádám Ürmös, Réka Karkas, Ákos Sükösd, Gábor Palánki, Attila Arany Tóth, Károly Erdélyi, Mihály Misó, Péter Gőbölös, Katalin Posta, Ferenc Kovács, Szilamér Ferenczi, Győző Horváth, László Szemethy, Zsuzsanna Szőke

“…We propose that inflammation during post-casting wound healing and consequent scar formation can trigger the development of PCD. …”
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New opportunities for preclinical diagnostics of antitumor therapy cardiotoxicity: results of an observational study by Yu. A. Vasyuk, D. A. Vyzhigin, E. Y. Shupenina, E. O. Novosel, E. A. Ulyanova

“…Patients with a very high risk of cardiotoxicity who were diagnosed with ischemic chronic heart failure or stable coronary artery disease, or post-myocardial infarction, were additionally recommended to take long-acting trimetazidine OD at a dose of 80 mg once daily. …”
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Cross-sectional survey on cancer patients’ concerns and consultation needs with pharmacists at the time of initial diagnosis by Tomofumi Watanabe, Atsunobu Sagara, Tomoya Abe, Masato Komuro, Koharu Yubune, Satoshi Yoshikawa, Hiroyuki Terakado

“…Abstract Background The immediate post-diagnosis period is a critical phase for cancer patients, marked by significant informational and emotional distress. …”
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The Battleship technique: A reliable method to quantify intraarticular distance maps patterns and correlate hindfoot alignment by Ben Efrima, Agustin Barbero, Amit Benady, Yair Green Halimi, Jari Dahmen, Gino M. M. J. Kerkhoffs, Jon Karlsson, Cristian Indino, Camila Maccario, Federico G. Usuelli

“…BST provides a standardized, non‐invasive method to evaluate intraarticular contact patterns, offering valuable insights for preoperative planning and post‐operative assessment. Its integration into practice may enhance surgical precision in complex realignment procedures. …”
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Transcriptomic, phenotypic and physiological analyses identify candidate regulators of Dendrobium stigma maturation and pollen-stigma interaction by Qian Wu, Shuxian Ren, Yuehong Ruan, Jiaxue Hu, Yin Li, Zongyan Li

“…Results Morphological observations of the four developmental stages of stigma maturation (day 1 post-anthesis [CK], early anthesis [T1], mid-anthesis [T2], and late anthesis [T3]) and investigations into the optimal receptivity window revealed that stigmatic mucilage secretion and viscosity peaked during the mid-anthesis phase (T2). …”
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Ultrastructural insights into early myoblast differentiation induced by shockwave stimulation by Larisa Ryskalin, Federica Fulceri, Paola Soldani, Maria Cristina D’Agostino, Gabriele Morucci, Stefania Moscato, Marco Gesi

“…Evaluations were conducted at 24 h, 72 h, and up to 7 days post-treatment, including cell viability, Western blot, histomorphometry, and ultrastructural analysis. …”
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Nafamostat Mesylate Regulates Glycosylation to Alleviate Aristolochic Acid Induced Kidney Injury by Pei Xie, Huijun Liu, Xingli Huo, Junlong Chen, Yu Li, Yu Huang, Zongning Yin

“…Acute kidney injury (AKI) is a condition with a poor prognosis, exacerbated by the lack of effective therapeutic options and inadequately understood underlying mechanisms. Glycosylation, a post-translational modification of proteins, is essential for maintaining protein stability and function, and its dysregulation leads to protein misfolding and amyloid aggregation. …”
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Molecular activity of bioactive phytocompounds for inhibiting host cell attachment and membrane fusion interacting with West Nile Virus envelope glycoprotein. by Noimul Hasan Siddiquee, Shanjida Akter Joyoti, Bushra Binte Zaker, Mansura Akter Eva, Alif Islam Nava, Nusrat Jahan Mridu, Al Amin Shawon, Sanjida Rahman, Tasnuva Jamil Chowdhury, Susmita Sarkar Katha, Md Rafiul Islam, Mohammad Sharif Uddin

“…The lead compounds and the control ligand both bind at the common active site of the macro-molecule, as evidenced by their interactions with the same amino acid residues at LEU281, ASN47, THR282, SER29, MET48, MET46, and MET45, correspondingly. In post-docking MM-GBSA the negative binding energy of the P-L complex for the compounds CIDs: 359, 9064, 25310, and 492405 (control) were -29.16, -33.45, -32.02, and -3.16 kcal/mol, correspondingly. …”
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Kyrgyz SSR During the Great Patriotic War: Demographic Processes and Challenges by Shaiyrkul Batyrbaeva, Anara Karyeva

“…In the context of modern trends of decolonization and de-Sovietization in postSoviet countries, especially in Central Asia, it is especially important to preserve the historical memory of the war and counteract distortions. …”
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Assessment of Knowledge, Attitude and Practices of Health Workers Towards Hepatitis B Virus Infection Prevention in Health Centers of Bushenyi District. by Byamukama, Julius

“…Nevertheless, I found that a relatively lower proportion of health workers knew that HBV has treatments (52.4 %) and post-exposure prophylaxis (67.1 %). This indicates that there is a need to alleviate the gaps as these might affect behaviors in seeking medical attention. …”
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Global Impacts Dataset of Invasive Alien Species (GIDIAS) by Sven Bacher, Ellen Ryan-Colton, Mario Coiro, Phillip Cassey, Bella S. Galil, Martin A. Nuñez, Michael Ansong, Katharina Dehnen-Schmutz, Georgi Fayvush, Romina D. Fernandez, Ankila J. Hiremath, Makihiko Ikegami, Angeliki F. Martinou, Shana M. McDermott, Cristina Preda, Montserrat Vilà, Olaf L. F. Weyl, Neelavar Ananthram Aravind, Ioanna Angelidou, Katerina Athanasiou, Vidyadhar Atkore, Jacob N. Barney, Tim M. Blackburn, Eckehard G. Brockerhoff, Clinton Carbutt, Luca Carisio, Pilar Castro-Díez, Vanessa Céspedes, Aikaterini Christopoulou, Diego F. Cisneros-Heredia, Meghan Cooling, Maarten de Groot, Jakovos Demetriou, James W. E. Dickey, Virginia G. Duboscq-Carra, Regan Early, Thomas G. Evans, Paola T. Flores-Males, Belinda Gallardo, Monica Gruber, Cang Hui, Jonathan M. Jeschke, Natalia Z. Joelson, Mohd Asgar Khan, Sabrina Kumschick, Lori Lach, Katharina Lapin, Simone Lioy, Chunlong Liu, Zoe J. MacMullen, Manuela A. Mazzitelli, John Measey, Agata A. Mrugała-Koese, Camille L. Musseau, Helen F. Nahrung, Alessia Pepori, Luis R. Pertierra, Elizabeth F. Pienaar, Petr Pyšek, Gonzalo Rivas Torres, Henry A. Rojas Martinez, Julissa Rojas-Sandoval, Ned L. Ryan-Schofield, Rocío M. Sánchez, Alberto Santini, Davide Santoro, Riccardo Scalera, Lisanna Schmidt, Tinyiko Cavin Shivambu, Sima Sohrabi, Elena Tricarico, Alejandro Trillo, Pieter van’t Hof, Lara Volery, Tsungai A. Zengeya

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