Overexpression of the ABA Synthesis Gene OsABA2 Enhances Seed Storability in Rice by Yongxiang Liao, Pengfei Jiang, Mingming Zhang, Fangli Jin, Mengyuan Li, Jiazhi Dong, Daiming Guo, Yingxiu Liao, Asif Ali, Saira Saleem, Xiangyang Zhang, Qinggui Jiang, Su Liu, Hongyu Zhang, Xiaoqiong Chen, Kangxi Du, Hao Zhou, Duo Xia, Peizhou Xu, Xianjun Wu

“…For practical application, Gang46B—a hybrid rice parental line with poor storability—significantly improved its post-aging germination rates. These findings demonstrate that the overexpression of OsABA2 enhances seed storability by regulating ABA biosynthesis pathway and associated oxidative response. …”
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Landscape analysis of m5C modification regulators unveils DNMT1-mediated dysregulated pyrimidine metabolism in hepatocellular carcinoma by Xuhui Zhao, Shengwei Mao, Yuan Fang, Jiafeng Chen, Lifu Bi, Jie Li, Jinglei Wu, Jun Gao, Shiguang Yang, Jialu Fu, Xiaoling Wu, Guiqi Zhu, Zheng Tang, Yinghong Shi, Jian Zhou, Jia Fan, Xingxing Zhang, Jinling Jiang, Weiren Liu

“…Abstract The 5-methylcytosine (m5C) post-transcriptional modification has been linked with the development and progression of a variety of cancers. …”
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Mechanistic Advances in the Therapeutic Application of Bixin for Lung Inflammation In Vitro and In Vivo by Alexsandro Tavares Figueiredo-Junior, Bruno Clemente Brandão Marques, Douglas Galdino dos Santos, Wesley Leandro Gouveia, Raysa Magali Pillpe Meza, Luzineide Wanderley Tinoco, Lídia Moreira Lima, Samuel Santos Valenca, Manuella Lanzetti

“…In the in vitro study, RAW 264.7 macrophages were exposed to CSE and post-treated with KBx to evaluate their ability to revert the redox imbalance caused by the stressor. …”
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A multivalent mRNA vaccine elicits robust immune responses and confers protection in a murine model of monkeypox virus infection by Yansheng Li, Lin Cheng, Lixu Jiang, Zhuohuan Li, Jing Rao, Tong Wu, Fangyan Zhang, Baocai Xie, Yu He, Lianrong Wang, Zheng Zhang, Shi Chen

“…Immune profiling reveals enhanced B- and T-cell receptor diversity and distinct CDR3 motifs post-vaccination. These findings demonstrate the potential of using mRNA-based multivalent vaccines as an effective strategy for preventing mpox and related Orthopoxvirus infections.…”
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Comparison of pathogen detection performance between metagenomic next-generation sequencing and conventional culture in organ preservation fluids and recipient wound drainage fluid... by Jiyuan Li, Wenjia Yuan, Chen Gao, Lei Liu, Lei Song, Wei Cao, Xuejing Zhu, Yachun Han, Ruobing Liang, Gongbin Lan, Shaojie Yu, Yu Wang, Liang Tan, Helong Dai, Xubiao Xie, Longkai Peng, Fenghua Peng

“…BackgroundPrompt identification and management of donor-derived infections post-kidney transplantation are critical. This study aims to assess the effectiveness of metagenomic next-generation sequencing (mNGS) in detecting pathogens within donor organ preservation fluids and recipient wound drainage fluids, with a comparison made against conventional culture methods.MethodsThis study involved 141 kidney transplant patients (May 1st, 2020 to Jan 31st, 2024). …”
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Echocardiographic evaluation of myocardial structural and functional changes in patients with stage 5 chronic kidney disease before and after kidney transplantation by M. Sh. Khubutiya, E. V. Shuvalova, O. N. Rzhevskaya, L. T. Khamidova, A. A. Ivannikov, Kh. G. Alidzhanova, A. G. Balkarov, I. V. Dmitriev

“…It was found that after 3 months post kidney transplantation, there was a decrease in the left atrium diameter, volume, and volume index. …”
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Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae by Ai Guo, Dianbao Zuo, Li Shi, Ming Guo, Jinquan Li, Caili Li, Puqing Wang, Xiaodong Sun, Ming Sang

“…The bacterial concentration markedly decreased at 2 h post-treatment, reaching its biological nadir by 6 h. …”
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Facing your fears in schools: using the ADIS/ASA to characterize anxiety and intervention outcomes in students with autism or suspected autism by Judy Reaven, Judy Reaven, Kelly T. Cosgrove, Kelly T. Cosgrove, Ainsley Losh, Ainsley Losh, Sarah Nickles, Sarah Nickles, Connor M. Kerns, Katherine Pickard, Audrey Blakeley-Smith, Audrey Blakeley-Smith, Lisa Hayutin, Lisa Hayutin, Allison T. Meyer, Allison T. Meyer, Caitlin Middleton, Caitlin Middleton, Nuri M. Reyes, Nuri M. Reyes, Richard E. Boles, Richard E. Boles

“…Caregivers completed the ADIS/ASA at baseline and post-intervention. The ADIS/ASA was administered by clinicians rigorously trained to reliability and masked to condition.ResultsStudents had both DSM-5 and distinct anxiety diagnoses at Time 1. …”
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Transcriptomic insights into the interplay between polyketide biosynthesis and other secondary metabolite biosynthetic clusters and biological pathways in entomopathogen Beauveria... by Wachiraporn Toopaang, Wachiraporn Toopaang, Wachiraporn Toopaang, Wachiraporn Toopaang, Thippawan Yoocha, Thippawan Yoocha, Chaiwat Naktang, Chaiwat Naktang, Nuchnudda Wichienchote, Phornsiri Pechsrichuang, Sithichoke Tangphatsornruang, Sithichoke Tangphatsornruang, Morakot Tanticharoen, Yu-Liang Yang, Yu-Liang Yang, Alongkorn Amnuaykanjanasin

“…Within the pks15 cluster, the UDP-glucosyl transferase gene Bbugt1 was consistently upregulated 3-fold in the WT in vivo compared to the WT in vitro armyworm group 48–96 h post-inoculation. In contrast, Bbugt1 was downregulated in Δpks15 in vivo compared to the WT in vivo during the same period. …”
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Molecular insights into the relationship between sustained CRP elevation and endothelial dysfunction in axial spondyloarthritis by Clementina López-Medina, Nuria Barbarroja, Alejandro Escudero-Contreras, Chary López-Pedrera, Carlos Perez-Sanchez, Pedro Segui, Eduardo Collantes, Jerusalem Calvo, Lourdes Ladehesa-Pineda, Desiree Ruíz-Vilchez, Laura Cuesta-López, Iván Arias-de la Rosa, Jesús Eduardo Martín-Salazar, Antonio Manuel Barranco, Miriam Ruiz-Ponce, María Ángeles Puche Larrubia, Rafaela Ortega, María Carmen Ábalos-Aguilera, Elena Moreno-Caño, Pedro Ortiz-Buitrago

“…Carotid intima-media thickness (CIMT) and microvascular endothelial function (post-ischaemic reactive hyperaemia) were measured. …”
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Effects of intermittent theta burst to the left dorsolateral prefrontal cortex on brain volumes and neurometabolites in people with alcohol use disorder: a preliminary investigatio... by Timothy C. Durazzo, Timothy C. Durazzo, Lauren H. Beauregard, Meng Gu, Eric P. Kraybill, Brian D. P. Joseff, Amy A. Herrold, Amy A. Herrold, Keith Humphreys, Keith Humphreys, M. Windy McNerney, M. Windy McNerney, Brian Knutson, Claudia B. Padula, Claudia B. Padula

“…Bilateral volumes of the rostral and caudal middle frontal and superior frontal gyri left DLPFC neurometabolites were quantitated pre- and post-iTBS sessions.ResultsOver the 2-week assessment interval, significant volume increases were observed, collapsed across groups, in the bilateral rostral and caudal middle frontal and superior frontal gyri, as well as in the left DLPFC choline-containing compounds. …”
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Abstract 032: Ovine Models for Cerebral Venous Catheter Access: A Single Center Experience by José M Morales, Naoki Kaneko, Gary R Duckwiler

“…A coil (Stryker Target) was deployed extravascularly from the 0.017" microcatheter for post‐mortem characterization (figure 3). Conclusion One of three experiments met criteria for success. …”
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Regreening Practices and Effectiveness Evaluation for Rocky Slope Drawdown Zones in Pumped Storage Power Station Reservoirs by YANG Zhi-chao, MA Xiao-xiao, CHANG Shi-ju, TANG Yu-shuang, ZHAO Rui-yi, WAN Dan, ZHANG Qian-zhu

“…Plants exhibited strong resilience in terms of post-submersion recovery, expansion, and colonization, achieving an overall survival rate of 83.2%. …”
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Transhumanism and New Challenges in Political Theories by Matin Anjomrooz, Mohammad Khezri

“…Furthermore, transhuman technologies challenge national and cultural identities by fostering hybrid or post-human identities, necessitating policies that can maintain social cohesion while respecting diversity. …”
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Voluntary Activity Wheel Running Improves Hyperammonaemia‐Induced Skeletal Muscle Molecular and Metabolic Perturbations in Mice by Annette Bellar, Avinash Kumar, Khaviyaa Chandramohan, Saurabh Mishra, Muaz Alsabbagh‐Alchirazi, Artem Astafev, Pugazhendhi Kannan, Amy Attaway, Roman Kondratov, Thomas Jaramillo, Lopa Mishra, Takhar Kasumov, Nicole Welch, Srinivasan Dasarathy

“…Indirect calorimetry was performed pre‐ and post‐intervention. Mice were euthanized 4 weeks after the start of VWR/UA, and organs (including muscles) were harvested, weighed, and muscle histomorphometry performed for fibre diameter/type. …”
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Hs-CRP, Diabetic Status, and Adverse Events Among Patients Receiving Statin Therapy Following PCI—A Prospective Registry-Based Study by Chen X, Wang HY, Sun W, Lin Z, Qiao Z, Bian X, Yin D, Feng L, Zhu C, Song W, Wang H, Jia L, Dong Q, Dou K

“…Residual inflammatory risk, defined as persistent inflammation despite lipid-lowering therapy, differs from residual cholesterol risk, which refers to suboptimal lipid levels post-treatment. This study aims to evaluate the impact of T2DM on the relationship between residual inflammatory risk, as assessed by a simple, economical, and easily measurable biomarker—high-sensitivity C-reactive protein (hs-CRP)—and clinical outcomes in statin-treated coronary heart disease (CHD) patients with drug-eluting stent (DES) implantation.Patients and Methods: 8,628 individuals with CHD treated with statins and DES implantation at Fuwai Hospital were included. …”
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Artesunate improves cryopreserved yak sperm quality by activating SOD1 antioxidant pathway by Yilin Fan, Yilin Fan, Weibing Lv, Weibing Lv, Xiaowei Li, Geri Wanma, Geri Wanma, Jian Li, Jian Li, Xianrong Xiong, Xianrong Xiong, Xiaoqiang He, Yanwen Wang, Shi Yin, Shi Yin, Wei Fu, Wei Fu, Honghong He, Honghong He, Yaqiu Lin, Yaqiu Lin, Daoliang Lan, Daoliang Lan, Yan Xiong, Yan Xiong

“…Artesunate (ART), derived from Artemisia annua and used for malaria treatment, shows potential as a frozen semen antioxidant.MethodsWe investigated the effects of various ART concentrations (0.2, 0.5, and 1.0 mM) on yak semen cryopreservation and examined the molecular mechanisms involved.ResultsPost-freezing, sperm quality markedly declined. However, 0.2 mM ART significantly improved sperm motility (both total and progressive) and reduced membrane damage. …”
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The role of ultra-high field MRI and image processing in the presurgical workup in MRI-negative focal epilepsy: A validated 7T MRI case study by Daniel Uher, Gerhard S. Drenthen, Christianne M. Hoeberigs, Rick H.G.J. van Lanen, Albert J. Colon, Roy A.M. Haast, Vivianne H.J.M. van Kranen-Mastenbroek, Guido Widman, Paul A.M. Hofman, Louis G. Wagner, Jan C. Beckervordersandforth, Jacobus F.A. Jansen, Olaf E.M.G. Schijns, Walter H. Backes

“…This case study illustrates that advanced image processing of ultra-high field structural and resting-state functional MRI scans may enhance the detection of subtle epileptogenic lesions in presurgical evaluation, potentially improving post-operative seizure outcome and associated quality of life.…”
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Case Report: “DEK::AFF2 fusion associated sinonasal carcinomas: a novel oncogenic driver and emerging therapeutic strategies” by Moritz Knebel, Moritz Knebel, Abbas Agaimy, Jan Philipp Kühn, Jan Philipp Kühn, Sandrina Körner, Sandrina Körner, Felix Braun, Felix Braun, Lukas Brust, Lukas Brust, Veronika Flockerzi, Veronika Flockerzi, Silke Wemmert, Silke Wemmert, Benedikt Balensiefer, Benedikt Balensiefer, Bernhard Schick, Umut Yilmaz, Umut Yilmaz, Malek Zaito, Malek Zaito, Alessandro Bozzato, Alessandro Bozzato, Maximilian Linxweiler, Maximilian Linxweiler

“…This allowed a shift to definitive chemoradiotherapy, with sustained disease-free status confirmed by a PET-CT three months post-treatment in July 2024. The second case involved a 66-year-old woman presenting with recurrent inverted papilloma affecting the sinonasal and tympanic regions. …”
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Protein oxidation and its effect on functional properties of livestock products during the processing and storage: A review by Jiamei Wang, Na Wu, Yao Yao, Shuping Chen, Lilan Xu, Yan Zhao, Yonggang Tu

“…The oxidation of proteins in livestock products readily occurs post-processing and storage through techniques such as freezing, cooking, ultrasonication, among others, leading to protein carbonylation and subsequent alterations in structure. …”
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