A New Strategy for the Treatment of Patients With Prolonged Impairment of Consciousness Using Xenon. Prospective Pilot Study by A. I. Shpichko, A. N. Kuzovlev, R. A. Cherpakov, N. P. Shpichko, O. A. Grebenchikov, A. K. Yevseyev, A. K. Shabanov, S. S. Petrikov

“…The anti-inflammatory effects of xenon inhalation anesthetic, which have been repeatedly shown in previous studies, have the potential to beneficially affect the level of consciousness in these patients by targeting key links of neuroinflammation.AIM OF STUDY To evaluate the effect of oxygen-xenon mixture inhalation on the level of consciousness recovery and the severity of spastic activity in patients after traumatic brain injury.MATERIAL AND METHODS A prospective randomized clinical trial of the effect of inhaled xenon sedation on the level of consciousness and spastic activity in patients with post-coma long-term impairment of consciousness was conducted. …”
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Impact of a Novel Pretreatment on Bond Strength of Universal Adhesive to Conventional and CAD/CAM Resin Composites: In Vitro Study by Ali A. Elkaffas, Abdullah Alshehri, Feras Alhalabi, Rania Bayoumi, Abdullah Ali Alqahtani, Abdulellah Almudahi, Abdulaziz Fahd Alsubaie, Abdulaziz Fahd Alharbi

“…A three-way analysis of variance (ANOVA) was used to analyze the μTBS data, followed by Tukey’s post hoc test. The μTBS values were not significantly affected by either the resin composite type (<i>p</i> > 0.05) or the adhesive strategy (<i>p</i> > 0.05) according to the three-way ANOVA results. …”
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Efficacy and safety analysis of combined resection and reconstruction of multi-organ and vital vascular in colorectal cancer surgery by Wang Shenfan, Wu Zhenjie, Shi Ting, Wu Yuxuan, Feng Xiang

“…[Conclusion] Combined resection and reconstruction of multi-organ and vital vascular in colorectal cancer surgery, demonstrate a high rate of R0 resections and manageable post-operative complications. Overall, this approach is deemed safe and viable.…”
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Peripheral Circulation and Astrocytes Contribute to the MSC-Mediated Increase in IGF-1 Levels in the Infarct Cortex in a dMCAO Rat Model by Xiaobo Li, Wenxiu Yu, Yunqian Guan, Haiqiang Zou, Zhaohui Liang, Min Huang, Renchao Zhao, Chunsong Zhao, Zhenhua Ren, Zhiguo Chen

“…In total, only 5-6% of Iba-1+ microglia were colabeled with IGF-1 in the infarct cortex, corpus callosum, and striatum at day 2 post-dMCAO. MSC transplantation did not lead to a higher proportion of Iba-1+ cells that coexpressed IGF-1. …”
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Cellulosomal hemicellulases: Indispensable players for ensuring effective lignocellulose bioconversion by Min Xiao, Ya-Jun Liu, Edward A. Bayer, Akihiko Kosugi, Qiu Cui, Yingang Feng

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Precision laser acupuncture at back-shu points enhances growth performance, feed efficiency, and hormonal regulation in rabbits by Mudhita Zikkrullah Ritonga, Ertika Fitri Lisnanti, Widya Pramita Lokapirnasari, Sri Hidanah, Saifur Rehman, Muhammad Fajar Amrullah, Rico Anggriawan, Mutasem Abuzahra, Denny Irmawati Hasan, Aamir Shehzad, Siti Rani Ayuti

“…Data were statistically evaluated using a one-way analysis of variance followed by Duncan’s post hoc test. Results: Group B showed significantly higher final body weight (1.97 ± 0.07 kg), weight gain (919 ± 128 g), GH levels (1.75 ± 0.12 ng/mL), improved FCR (2.67 ± 0.07), and greater FE (37.45% ± 1.09%) compared to Groups A and C (p < 0.05). …”
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Exploiting phKL-mediated homoeologous recombinants to map stripe rust resistance gene YrAev from Aegilops variabilis by Ming Hao, Yazhou Li, Chaolan Fan, Hong Chen, Yongxin Nie, Fang Wang, Jiangtao Luo, Bo Jiang, Xue Chen, Xuejiao Chen, Zhongwei Yuan, Shunzong Ning, Lianquan Zhang, Zongjun Pu, Dong Cao, Shisheng Chen, Lin Huang, Baolong Liu, Dengcai Liu

“…Differential gene expression analysis of post-inoculation with the Pst race has indicated two disease-resistance-related genes (annotated as mixed lineage kinase domain-like protein and nucleotide-binding leucine-rich repeat like protein, respectively) as promising candidates for YrAev. …”
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Combination of Ketorolac Tromethamine and Prednisolone-Loaded PLGA Nanocomposite for Effective Chronic Pain Relief in Mice by Do TN, Liu YC, Chuang YC, Tsai TL, Wu PC

“…Tuyet-Nhi Do,1 Yen-Chin Liu,2– 4 Yu-Che Chuang,5 Tsung-Lin Tsai,1,6,7 Ping-Ching Wu1,6,8– 10 1Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, 701, Taiwan; 2School of Post-Baccalaureate, College of Medicine, Kaohsiung Medical University, Kaohsiung, 812, Taiwan; 3Department of Anesthesiology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 812, Taiwan; 4Department of Anesthesiology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan; 5Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, 112, Taiwan; 6Center of Applied Nanomedicine, National Cheng Kung University, Tainan, 701, Taiwan; 7Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan; 8Institute of Oral Medicine and Department of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan; 9Medical Device Innovation Center, Taiwan Innovation Center of Medical Devices and Technology, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, 701, Taiwan; 10University Center of Bioscience and Biotechnology, National Cheng Kung University, Tainan, 701, TaiwanCorrespondence: Ping-Ching Wu, Department of Biomedical Engineering, National Cheng Kung University, Tainan, 701, Taiwan, Email wbcxyz@gmail.com Tsung-Lin Tsai, Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan, Email sloantsai@mail.ncku.edu.twIntroduction: Chronic pain is a complex condition that requires timely and effective management to prevent long-term emotional, social, and economic consequences. …”
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[Translated article] Complications of intraosseous administration of vancomycin in total hip arthroplasty by W.F. Martínez, L. Camacho Terceros, F. Garbini, E.J. Bochatey, F.A. Lopreite

“…Detailed records and documentation of complications during hospitalisation and the first three months post-surgery were maintained. As a secondary outcome measure, the incidence of PJI was explored. …”
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Impact of Storage Conditions on Bronchoalveolar Lavage Fluid Analysis: A Human Study by Yu Shionoya, Kanae Maruyama, Takeshi Kawasaki, Mayumi Ono, Yushi Murai, Ryutaro Hirama, Dai Horiuchi, Noriko Sakuma, Shinsuke Kitahara, Shun Sato, Kohei Takahashi, Yoshihito Ozawa, Takuji Suzuki

“…Notably, neutrophil percentages showed a significant decline over time under both storage conditions—at 4 °C (<i>p</i> = 0.02) and at room temperature (<i>p</i> < 0.01). Post hoc tests revealed a notable decreasing trend at 6 h and significant reductions by 24 h at 4 °C (<i>p</i> = 0.09 and <i>p</i> = 0.02, respectively), and significant decreases at both 6 and 24 h at RT (<i>p</i> = 0.01, <0.01). …”
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The role of prefrontal cortex in chronic low back pain with comorbid depression: A resting-state fMRI study by Yanqiao Zhao, Chen Gong, Pan Zhu, Suimin Guo, Yangyang Lin, Yafei Wang, Beibei Feng, Xiaochun Meng, Yuling Wang

“…Analysis of variance and post hoc analyses among groups were conducted. Correlational analyses were performed between neuroplasticity and clinical variables. …”
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Freehand ventricular catheter placement in ventriculoperitoneal shunt surgery is associated with higher rates of proximal catheter failure compared to image guidance by Nikhil Sharma, Jeffery R. Head, Regan M. Shanahan, Shovan Bhatia, Michael R. Kann, Sydney Scanlon, Amogh Vellore, Michael Raver, Hussam Abou-Al-Shaar, Nicolas M. Kass, Fritz Steuer, Lucille Cheng, Stephen P. Canton, Arka N. Mallela, Peter C. Gerszten, Edward G. Andrews

“…VC revision is associated with inaccurate placement and highly inaccurate VCs (>2 cm TTF) are more likely to require revision in the immediate post-operative period.…”
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Influence of body mass index on cardiovascular risk in rheumatoid arthritis varies across anti-citrullinated protein antibody status and biologic use by George Athanasios Karpouzas, Anne Grete Semb, Ellen-Margrethe Hauge, Dionicio Angel Galarza-Delgado, Miguel A González-Gay, Solbritt Rantapää-Dahlqvist, Petros P Sfikakis, Virginia Pascual-Ramos, Irazú Contreras-Yáñez, Carol Hitchon, Elena Myasoedova, Durga Prasanna Misra, Iris J Colunga-Pedraza, Alfonso Corrales, George Kitas, José Ramón Azpiri-lópez, Sarah R Ormseth, Patrick Dessein, Piet Leonardus Cornelis Maria van Riel, Durez Patrick, Brian Bridal Logstrup

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Transcatheter Aortic Valve Replacement in Patients With Small Aortic Annulus: An Observational Study by Hanad Bashir, MD, Christian W. Schmidt, MS, Kofi Ansah, MD, Gustavo Mendez-Hirata, MD, Geoffrey A. Answini, MD, J. Michael Smith, MD, Saad Hasan, MD, Jeffrey Griffin, MD, Robert Dowling, MD, Dean J. Kereiakes, MD, Puvi Seshiah, MD, Joseph Choo, MD, Zaid Alirhayim, MD, Santiago Garcia, MD

“…Comorbidities and risk profiles were well balanced between groups. At 30 days post-transcatheter aortic valve replacement, SEV had lower aortic valve mean gradients (8 mmHg [6, 11] vs. …”
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Hepatic resection for recurrent hepatocellular carcinoma during pregnancy: a case report by Takashi Maeda, Daisuke Imai, Huanlin Wang, Kyohei Yugawa, Nao Kinjo, Koto Kawata, Shinichiro Ikeda, Keitaro Edahiro, Kazuki Takeishi, Tomohiro Iguchi, Hiroto Kayashima, Noboru Harada, Mizuki Ninomiya, Shohei Yamaguchi, Kozo Konishi, Shinichi Tsutsui, Hiroyuki Matsuda

“…Case presentation A 36-year-old woman underwent laparoscopic partial hepatectomy for HCC (20 mm in diameter) in segment 5 of the liver during follow-up after being determined as a hepatitis B virus carrier two and a half years ago. Post-surgery follow-up abdominal ultrasonography revealed a 36-mm tumor in segment 7 of the liver. …”
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Efficacy and mechanism of action of cipargamin as an antibabesial drug candidate by Hang Li, Shengwei Ji, Nanang R Ariefta, Eloiza May S Galon, Shimaa AES El-Sayed, Thom Do, Lijun Jia, Miako Sakaguchi, Masahito Asada, Yoshifumi Nishikawa, Xin Qin, Mingming Liu, Xuenan Xuan

“…Combining CIP with TQ effectively eliminated B. microti infection in SCID mice with no relapse, and parasite DNA was not detected by qPCR within 90 days post-infection. Our findings reveal the efficacy of CIP as an antibabesial agent, its limitations as a monotherapy due to resistance development, and the potential of combination therapy with TQ to overcome said resistance and achieve complete parasite clearance.…”
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Induction of reproduction of fish Anasa Nomorhampus sp. endemic Palu, Central Sulawesi orally through hormon bioencapsulation use Chironomus sp. by Dinda Wahyu Rezki, Agus Oman Sudrajat, Dinar Tri Soelistyowati, Odang Carman

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Staphylococcus epidermidis uses the SrrAB regulatory system to modulate oxidative stress and intracellular survival in mouse macrophage cell line Ana-1 by Chunjing Zhao, Zongkai Bai, Xiaoting Chen, Shuangjie Shang, Baitong Shen, Li Bai, Di Qu, Yang Wu, Youcong Wu

“…Compared to SE1457, the viable cell counts of the ∆srrAB mutant significantly decreased in the post-stationary phase culture, coinciding with a sharp increase in reactive oxidative species (ROS) accumulation. …”
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Effects of Dietary Supplementation with Extruded Linseed on Growth Performance and Meat Quality of Young Holstein Bulls by Stella Dokou, Maria Eleni Filippitzi, Anestis Tsitsos, Vasiliki Papanikolopoulou, Stergios Priskas, Vangelis Economou, Eleftherios Bonos, Ilias Giannenas, Georgios Arsenos

“…Adding extruded linseed did not result in differences in meat quality traits (<i>p</i> > 0.05), except for meat pH, which was significantly decreased in the LS group (<i>p</i> < 0.05), indicating more efficient post-mortem glycolysis. Finally, the inclusion of extruded linseed resulted in higher levels of α-linolenic acid in the meat (<i>p</i> < 0.05). …”
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Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment by Máté Kiss, Laszlo Halasz, Eva Hadadi, Wilhelm K. Berger, Petros Tzerpos, Szilard Poliska, Daliya Kancheva, Aurélie Gabriel, Romina Mora Barthelmess, Ayla Debraekeleer, Jan Brughmans, Yvon Elkrim, Liesbet Martens, Yvan Saeys, Bence Daniel, Zsolt Czimmerer, Damya Laoui, Laszlo Nagy, Jo A. Van Ginderachter

“…Epigenomic features, such as post-translational modification of histones and chromatin accessibility, are key determinants of transcription factor binding and thereby play an important role in controlling transcriptional responses to the tissue environment. …”
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