Efficacy of sacubitril/valsartan on improving clinical symptoms in patients with acute myocardial infarction complicated with heart failure: a retrospective study by Guiping Wang, Ruolin Zhang, Xuyang Li, Shuping Zuo, Boheng Zhang, Yanan Zhao, Suya Sun, Juanjuan Zhang, Xiaokun Liu

“…Follow-up assessments were conducted 1 year post-discharge to evaluate NT-proBNP levels, and symptom progression. …”
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The Risk of Developing Tinnitus and Air Pollution Exposure by Po-Yu Lai, Chang-Yin Lee, Kuang-Hsi Chang, Yu-Kang Chang, Yi-Chao Hsu, Ing-Ming Chiu, Stella Chin-Shaw Tsai, Der-Yang Cho, Cheng-Li Lin, Tsung-Hsing Lin, Wu-Lung Chuang

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Evaluation of the efficiency and safety of combined therapy with a symptomatic sustained-release drug and hyaluronic acid versus monotherapy with hyaluronic acid in patients with... by K. A. Berdyugin, I. V. Kadyntsev, O. V. Berdyugina, E. A. Taskina, N. G. Kashevarova

“…Searching for new treatment methods and regimens for OA is relevant.Objective: to evaluate the efficiency and safety of therapy with a symptomatic sustained-release drug (Alflutop) in combination with intra-articular hyaluronic acid (HA) injection versus monotherapy with HA in patients with knee OA in routine clinical practice.Patients and methods. A post-registration open-labeled prospective comparative randomized study was conducted to assess the results of treatment in 76 patients (31 men and 45 women; mean age, 49.3±8.5 years; body mass index, 28.4±0.8 kg/m2 ) in two clinical centers in Yekaterinburg and Perm. …”
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Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome by Fang Yu, Yan Meng, Xiaoyue Wang, Jia Chen, Junling He, Xiangling Yi, Yani He, Kehong Chen

“…Notably, the rate-limiting enzyme citrate synthase (CS) exhibits significantly elevated lactylation levels post-AKI induction, and K370 was the most significant lysine residue. …”
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Trichinella spiralis adult excretory-secretory antigen promotes peripheral regulatory T cell differentiation and attenuates experimental colitis via TGF-β-like mechanisms by Xi-Meng Sun, Ze-Ni Luo, Wei Wang, Chun-Yue Hao, Zhi-Ang Li, Saeed El-Ashram, Xin-Ping Zhu

“…Foxp3eGFP mice subsequently received intraperitoneal injections of TsAES (20 µg/mouse) biweekly for a total of three doses. On day 8 post-model induction, mice were euthanized and colonic tissues collected for immunofluorescence and flow cytometric analysis to assess pTreg populations. …”
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Diagnosis and treatment of synthetic mid-urethral sling complications by Helen E. O’Connell, Christopher K. Harding, Gaurav Khatri, Phyllis Glanc, Eric Bautrant, Sarah Love-Jones, Karen Ward, Henry H. Yao, Ventia Hoe, Charlotte Korte, Nicolle Germano, Sanjeevan Kalavampara, Sherif Mourad, Hashim Hashim

“…Complications arise in a small proportion, occurring acutely in the perioperative stage, post-operatively and in a delayed fashion many years after implantation. …”
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Associations of neurodegenerative and cerebrovascular neuropathology with frailty in a diverse sample by Felipe Bozi-Soares, Márlon Juliano Romero Aliberti, Alberto Fernando Oliveira Justo, Renata E. P. Leite, Lea T. Grinberg, Vitor R. Paes, Roberta D. Rodriguez, Carlos A. Pasqualucci, Eduardo Ferrioli, Claudia Kimie Suemoto

“…Frailty was measured using a frailty index from 33 health deficits, and cognitive impairment was defined as a Clinical Dementia Rating ≥ 0.5, both based on post-mortem informant reports with the next of kin. …”
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Comparing the efficacy of hyaluronic acid products with various molecular weights as mono and combined with chondroitin sulfate regimens in treatment of patients with stage I–III k... by V. E. Bialik, M. A. Makarov, E. I. Bialik, S. A. Makarov, V. A. Nesterenko, M. R. Nurmukhametov

“…IA HA injections were performed 160 patients with primary and post-traumatic knee OA of the I–III stages at the department of traumatology-orthopedics, V.A. …”
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The Vertebral Bone Marrow clot as cell therapy and multifunctional bioscaffold for spinal fusion surgery: protocol for a randomized clinical trial by Maria Sartori, Giuseppe Tedesco, Paolo Spinnato, Antonio Mazzotti, Antonio Mazzotti, Alessandro Gasbarrini, Alessandro Gasbarrini, Cesare Faldini, Cesare Faldini, Marco Miceli, Gianluca Giavaresi, Francesca Salamanna

“…Complications are also recorded and classified as early (major and minor) or late, according to the time of occurrence and findings at 12 months post-surgery. Finally, the preclinical project outcome is to define the biological and anti-inflammatory properties of vBMA clot and demonstrate its antibacterial effect, assessing age and gender differences and including an examination of their interactions.Clinical trial registrationClinicalTrials.gov, identifier NCT05947175.…”
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Perceptions and satisfaction with the quality of clinical training placements among nursing and midwifery students in Northern Ghana by Abubakari Wuni, Mudasir Mohammed Ibrahim, Maximous Diebieri, Brenda Abena Nyarko, Mohammed Awal Salifu, Hussein Abubakar Abdul-Karim, Godfred Prince Kwaku Atiku, Tina Wepeamo Wepeba, Waliu Jawula Salisu, Sufyan Bakuri Suara, Iddrisu Sisala Mohammed

“…Hypothetical relationships between students’ perceptions of clinical training quality, satisfaction, and demographics were tested using One-way ANOVA, t-tests, and Pearson correlation. Tukey LSD post hoc analysis assessed pairwise differences, and statistical significance was pegged at P < 0.05. …”
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Proportion and factors associated with fertility desires among human immunodeficiency virus-positive adults receiving antiretroviral therapy in Northeast Ethiopia by Abel Endawkie, Biresaw Derese, Kidist Adamu, Getaw Walle

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Are treatment plans optimized on the basis of acuros XB dose calculation robust against anatomic changes during online adaptive radiotherapy for lung cancer regarding dose homogene... by Khouya Aymane, Santiago Alina, Ringbaek Toke, Guberina Nika, Guberina Maja, Gauler Thomas, Lübcke Wolfgang, Zylka Waldemar, Pöttgen Christoph, Stuschke Martin

“…The adaptive plans were verified on a subsequent post-adaptation CBCT (CBCT2) of the same dose fraction. …”
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Scoping review on assessing climate-sensitive health risks by Chalachew Yenew, Gashaw Melkie Bayeh, Asaye Alamneh Gebeyehu, Anley Shiferaw Enawgaw, Zufan Alamrie Asmare, Amare Genetu Ejigu, Tilahun Degu Tsega, Abathun Temesgen, Rahel Mulatie Anteneh, Zeamanuel Anteneh Yigzaw, Getasew Yirdaw, Sintayehu Simie Tsega, Ahmed Fentaw Ahmed, Almaw Genet Yeshiwas

“…Additionally, climate change exacerbates mental health issues, leading to conditions like post-traumatic stress disorder (PTSD), anxiety, and depression. …”
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Determination of the Stage of Periodontitis with 20 ng/mL Cut-Off aMMP-8 Mouth Rinse Test and Polynomial Functions in a Mobile Application by Miika Penttala, Timo Sorsa, Julie Toby Thomas, Andreas Grigoriadis, Dimitra Sakellari, Vaibhav Sahni, Shipra Gupta, Pirjo Pärnänen, Tommi Pätilä, Ismo T. Räisänen

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Unveiling Sodium Diffusion Kinetics and Locking Mechanisms for High‐Performance CZTSSe Photovoltaics by Shuyu Li, Chaoran Li, Chu Liu, Jiachen Wu, Letu Siqin, Yuan Li, Guonan Cui, Yanchun Yang, Ruijian Liu, Hongmei Luan, Chengjun Zhu

“…By establishing critical correlations between post‐processing thermal protocols and alkali metal migration dynamics, how synchronized extension of sintering duration and rapid cooling termination creates a non‐equilibrium state that traps Na at strategic interfacial positions is demonstrated. …”
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Zwitterion nanocomposite hydrogels with bioactivity and anti-adhesion properties for rapid prevention of postoperative and recurrent adhesion by Weihan Zhu, Jintao Fang, Wenjun Xu, Dian Yu, Jintao Shi, Qing Xia, Jinwei Wang, Xiaohui Chen, Haorui Zha, Shengyu Li, Wei Zhang

“…Therefore, the pSBLA hydrogel has considerable potential for preventing post-operative adhesions in clinical settings.…”
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Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep by Samantha J. Murray, Mustafa M. Almuqbel, Simon A. Felton, Nickolas J. Palmer, Ashley R. Deane, Daniel J. Myall, Reza Shoorangiz, Arsène Ella, Matthieu Keller, David N. Palmer, Tracy R. Melzer, Nadia L. Mitchell

“…A naturally occurring model of CLN5 NCL exists in New Zealand Borderdale sheep, which exhibit similar clinical disease and post‐mortem pathology to the human disease. Recent trials of concurrent intracerebroventricular and intravitreal gene therapy in sheep with CLN5 disease confirmed the therapeutic efficacy of this approach. …”
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A Novel One-Stop Multidisciplinary Clinic for Chronic Postoperative Inguinal Pain: Initial Experiences and Outcomes by Federica Cocciolo, Alice Birch, Maciej Pawlak, Lucy Miller, Alan Bennett, Matthew Lund, David Sanders, John M. Findlay, John M. Findlay, John M. Findlay

“…BackgroundChronic Postoperative Inguinal Pain (CPIP) affects 10%–20% of patients following inguinal hernia repair, persisting for over 3 months post-surgery. It involves a complex interplay of neuropathic and nociceptive pain, secondary sensitization, and functional and psychological impacts. …”
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Oxidative stress in the liver of chicken during fowl adenovirus serotype 4 infection by Jiayu Sun, Xu Cao, Yufeng Li, Kexiang Yu, Yanfang Cong, Qing Pan, Yanbo Yin, Jianlin Wang

“…Samples were collected from each group at 2, 4, and 6 days post-infection (dpi), and sera were collected to measure the levels of ALT and AST. …”
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Nematocidal Activity of a Variety of Plants Used in Mexico Against <i>Strongyloides venezuelensis</i> by Joel H. Elizondo-Luévano, Abelardo Chávez-Montes, Antonio Muro, Belén Vicente-Santiago, Miroslava Kačániová, David G. García-Hernández, Aldo F. Bazaldúa-Rodríguez, Horacio Larqué-García, Uziel Castillo-Velázquez, Julio López-Abán

“…The methanolic extracts of <i>A. mexicana</i>, <i>J. dioica</i>, <i>L. graveolens</i>, and <i>T. vulgaris</i> exhibited significant activity against L3 cultures at 72 and 96 h post-incubation. None of the extracts showed hemolytic effects on red cells or Vero cells. …”
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