Effects on choroid after repeated low-level red-light therapy in preclinical and clinical myopic children: a randomized controlled trial by Hongyu Wei, Sahil Thakur, Qin Zhu, Yanrong Zhou, Xuejun Cao, Shuyuan Xiao, Qin Chen, Min Hu, Hua Zhong

“…Improvements on choriocapillaris blood flow were evident at 3 months post-RLRL, yet these changes were not sustained and did not correlate with longer-term choroidal thickening. …”
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Optimising aesthetic outcome after nipple-areola complex-sparing mastectomy and immediate one-stage prosthetic reconstruction: A simple surgical trick to fix nipple-areola complex... by Luca Maione, Andrea Lisa, Federico Barbera, Mattia Siliprandi, Valeriano Vinci, Francesco Klinger, Marco Klinger

“…An optimum result obtained at the end of surgical procedure may be altered and compromised by skin redistribution and consequently NAC depositioning during the post-operative period in patients with medium-sized breasts and a moderate degree of ptosis. …”
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Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study by Jiajing Chen, Lixin Chen, Kexin Jiang, Dandan Wang, Chunyu Wu, Yuenong Qin, Sheng Liu

“…BackgroundChemotherapy-related cognitive impairment (CRCI) affects up to 75% of breast cancer patients during treatment, with 35% experiencing persistent post-treatment deficits. Current interventions show limited efficacy, creating urgent need for targeted therapies. …”
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Retrospective Analysis of Prognostic Factors and Pregnancy Outcomes in Patients with Moderate-to-Severe Intrauterine Adhesions Following Hysteroscopic Adhesiolysis and Modified Int... by Peng Q, Cao CX, Chen YN, Liu WC, Zhao RK, Jiang QJ, Zhou Q

“…A comprehensive follow-up period of 2 years post-stent removal was instituted.Results: The occurrence of adhesion recurrence increased progressively, demonstrating a recurrence rate of 11.54% at hysteroscopic reevaluation administrated in 3 months after surgery and surging to 32.69% during the 2-year follow-up period. …”
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Predicting IDH and 1p/19q molecular status of gliomas with multi-b values DWI by Shanshan Zhao, Peipei Wang, Eryuan Gao, Mengzhu Wang, Guang Yang, Shouhui Niu, Mengjiao Pan, Kai Zhao, Jingliang Cheng, Xiaoyue Ma

“…Multi-b-value DWI images were post-processed to generate parametric maps based on the mono-exponential (Mono), the intravoxel incoherent motion (IVIM), the stretched exponential model (SEM) and the continuous-time random walk (CTRW) models. …”
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Spatial Distribution of Cadmium in Avocado-Cultivated Soils of Peru: Influence of Parent Material, Exchangeable Cations, and Trace Elements by Richard Solórzano, Rigel Llerena, Sharon Mejía, Juancarlos Cruz, Kenyi Quispe

“…For data analysis, we applied (1) univariate statistics (skewness, kurtosis); (2) multivariate methods such as Spearman correlations and principal component analysis (PCA); (3) spatial modeling using the Geodetector tool; and (4) non-parametric testing (Kruskal–Wallis test with Dunn’s post hoc test). Our results indicated (1) the presence of hotspots with Cd concentrations exceeding 3 mg·kg⁻¹, displaying a leptokurtic distribution (skewness = 7.3); (2) dominant accumulation mechanisms involving co-adsorption and cation competition (Na⁺, Ca²⁺), as well as geogenic co-accumulation with Zn and Pb; and (3) significantly higher Cd concentrations in Leptosols derived from Cretaceous intermediate igneous rocks (diorites/tonalites), averaging 1.33 mg kg⁻¹ compared to 0.20 mg·kg⁻¹ in alluvial soils (<i>p</i> < 0.0001). …”
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Gene expression profiling in pure neural leprosy: insights into pathogenesis and diagnostic biomarkers by Mariana Martins de Athaide, Thyago Leal-Calvo, Tatiana Pereira Da Silva, Thabatta Leal Silveira Andrezo Rosa, Helen Ferreira, Bernardo Miguel de Oliveira Pascarelli, Ana Caroline Siquara de Sousa, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Marcia Rodrigues Jardim, Roberta Olmo Pinheiro, Roberta Olmo Pinheiro, Roberta Olmo Pinheiro

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Association between vitamin D receptor gene polymorphisms and athletic performance in Chinese male youth soccer players by Shidong Yang, Wei Zhang, Meng Jia, Haichun Chen

“…One-way analysis of variance and Bonferroni’s post hoc test were implemented to analyze the differences in parameters among groups, and statistical significance was set at p ≤ 0.05. …”
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Computer vision applications for the detection or analysis of tuberculosis using digitised human lung tissue images - a systematic review by Kapongo D. Lumamba, Gordon Wells, Delon Naicker, Threnesan Naidoo, Adrie J. C. Steyn, Mandlenkosi Gwetu

“…Conclusion The literature indicates that post 1950s, TB was predominantly studied using animal models even though no animal model reflects the full spectrum of human pulmonary TB disease and does not reproducibly transmit Mtb infection to other animals (Hunter, 2011). …”
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Evaluating the multitargeted potency of Pixuvri against cell cycle regulation proteins in cervical cancer by Mohammed Ali Alshehri, Hadil Alahdal, Akram Ahmed Aloqbi, Afnan Mohammed Shakoori, Ghadir Sindi, Rehab M. Bagadood, Nida Alsaffar, Mohammad Ahmad Alobaidy, Noof Abdulrahman Alrabiah, Md Khursheed, Abeer Al Tuwaijri, Abeer Al Tuwaijri

“…In this study, we screened Selleckchem approved library against cervical cancer proteins that regulate the cell cycle, particularly during mitosis and cell division (PDBIDs: 2VFX, 2WVI, 3KND, 4N14) using HTVS, SP, and XP docking followed by MMGBSA post-processing. Pixuvri (Pixantrone Maleate) emerged as the top candidate with docking scores of -5.234 to -9.218 kcal/mol and MMGBSA scores of -39.22 to -53.87 kcal/mol. …”
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A phase 4, open-label, multicenter study of the safety and efficacy of agalsidase beta in Chinese patients with Fabry disease by Hong Ren, Wei Zhang, Yan Ouyang, Junhong Guo, Hong Xu, Jie Ma, Xiaoping Luo, Xiaoxia Pan, Yun Yuan, Wei Zhang, Qian Shen, Bin Li, Qiqi Feng, Shi Liu, Nan Chen

“…The endpoints of efficacy included changes in plasma globotriaosylceramide (GL-3), globotriaosylsphingosine (Lyso-GL-3), symptoms and estimated glomerular filtration rate (eGFR) from baseline to week 48. A post-hoc subgroup analysis was conducted by age group (< 30 years and ≥ 30 years) and in patients with or without COVID-19 infection. …”
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Recurrent hyponatremia due to syndrome of inappropriate antidiuresis after traumatic brain injury: two case reports by Iulia Petria, Iulia Petria, Rita Indirli, Rita Indirli, Beatrice Mantovani, Valeria Lanzi, Valeria Lanzi, Giovanna Mantovani, Giovanna Mantovani, Emanuele Ferrante

“…Consistently, olanzapine-related hyponatremia could be ruled out and post-traumatic SIAD confirmed.Case 2A 37-year-old man experienced TBI with diffuse axonal injury falling during a mountain trip. …”
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Heart transplantation in patients undergoing extracorporeal cardiopulmonary resuscitation in in‑hospital cardiac arrest by V. N. Poptsov, E. A. Spirina, A. K. Solodovnikova, A. S. Epremyan, A. A. Kuznetsova, A. S. Ignatkina, G. B. Glinkin, S. A. Budagaev

“…The cause of death (n = 4; 15.3%) in the early post-HT period was irreversible multiple organ dysfunction.Conclusion. …”
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Plasma longitudinal metabolic changes with acute maximal aerobic exercise and one-hour recovery by William A. Fountain, Stefano Donega, Nirad Banskota, Ruin Moaddel, Mona Patel, Linda Zukley, Sarah Church, Katie Bustin, Josephine M. Egan, Josephine M. Egan, Jeremy Walston, Luigi Ferrucci

“…This study examined metabolic changes during each person’s peak aerobic exercise and one-hour post-exercise recovery in 29 Baltimore Longitudinal Study of Aging (BLSA) participants.MethodsBlood samples were collected at baseline, and at 3-min intervals during both incremental exercise on a treadmill until exhaustion and during recovery. …”
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From Breathlessness to Better Living: Transforming COPD Care with Home-Based Pulmonary Rehabilitation by Abins Thozhuthinkal Kasim, Ravi Gaur, Nitesh Manohar Gonnade, Nagma Sheenam, Chinchu Kolakkanni, Sarankumar Ganesan, Adharshna Thangamalai Kannan

“…Methods A prospective, single-arm pre–post interventional study was conducted among 62 COPD patients at All India Institute of Medical Sciences, Jodhpur. …”
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Therapeutic effects of Jing Si herbal tea for chronic obstructive pulmonary disease: a comprehensive investigation from clinical to basic research by Chou-Chin Lan, Chou-Chin Lan, Po-Chun Hsieh, Kuo-Liang Huang, Kuo-Liang Huang, Mei-Chen Yang, Mei-Chen Yang, Guan-Ting Liu, Chan-Yen Kuo, I.-Shiang Tzeng, Yao-Kuang Wu, Yao-Kuang Wu

“…Cellular studies on lipopolysaccharide (LPS)-stimulated A549 cells demonstrated that JSHT effectively reduced the release of DAMPs such as HMGB1, FPR1, and extracellular ATP, and decreased the expression of inflammatory markers including pMAPK, pJNK, NF-kB, and cCaspase 3, and pro-inflammatory cytokines like IL-1, IL-6, IL-8, and TNF-α post-LPS induction.ConclusionJSHT improved the HRQL in patients with COPD, both in stable and exacerbated states. …”
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Individual Variation in Migration and Wintering Patterns of Long‐Tailed Ducks Clangula hyemalis From a Population in Decline by Thiemo Karwinkel, Ingrid L. Pollet, Sandra Vardeh, Julia Loshchagina, Petr Glazov, Alexander Kondratyev, Aleksandr Sokolov, Vasiliy Sokolov, Julius Morkūnas, Daniela J. Tritscher, Juan F. Masello, Götz Eichhorn, Helmut Kruckenberg, Petra Quillfeldt, Jochen Bellebaum

“…Females moved from freshwater breeding sites to mostly marine post‐breeding sites after wing moult. For wintering, the majority of the birds (94%) migrated to the Baltic Sea, while the rest overwintered in the White and Barents Seas. …”
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Stable water isotope analysis of plant-soil interspecific interactions in wheat-maize intercropping by Duo-Peng Shi, Ying-Bo Liu, Yun-Ling Cui, An-Yu Zhao, He-Zhe Sun, Liang Xue, Wen-Feng Cong, Muhammad Ali Raza, Li-Qin Zhang

“…Middle-row maize showed 75 % higher flowering-stage biomass than border rows, attributed to preferential water use from middle soil layer (28 %), which reduced interspecific competition. Post wheat harvest, deep soil water storage in the maize strip increased by 8 %. …”
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A randomized controlled trial of anodal transcranial direct current stimulation (A-tDCS) and olfactory training in persistent COVID-19 anosmia by Lucilla Vestito, Marta Ponzano, Laura Mori, Carlo Trompetto, Fabio Bandini, Riccardo Canta, Anna De Giovanni, Simone Strano, Andrea Pagani

“…We also evaluated the long-term effectiveness of this intervention at both one- and six-months post-treatment assessments. Methods: This RCT involved 52 patients with persistent hypo/anosmia due to COVID-19. …”
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Research progress on the interaction between glucose metabolic reprogramming and lactylation in tumors by Yi Yang, Yi Yang, Yi Wu, Yi Wu, Hui Chen, Hui Chen, Zehai Xu, Zehai Xu, Ruisi Lu, Ruisi Lu, Sijie Zhang, Sijie Zhang, Rui Zhan, Rui Zhan, Qinghua Xi, Qinghua Xi, Yunfeng Jin, Yunfeng Jin

“…Lactylation represents a newly identified post-translational modification (PTM) that occurs due to lactate accumulation and is observed in various proteins, encompassing both histone and non-histone types. …”
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