Ultrasound combined with microbubble enhanced renoprotective effects of NLRP3 inflammasome inhibitor MCC950 in CKD model by Wen Wen, Bin Tu, Xiaomei Ren, Yangli Liu, Rufang Jiang, Xiaofeng Wu, Jian Liu

“…Ultrasound (mechanical index 0.99) was applied over the kidneys for 10 min every 2 days for six sessions post-injection. Renal function was assessed from urine and blood samples. …”
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Who learns more: the impact of dual-player and single-player modes in a serious game on dental students’ factual knowledge by Felix Krause, Ben Horn, Andreas Braun, Sebastian Fedrowitz, Laura Bell, Martin Lemos

“…After the intervention phase, both groups completed a post-knowledge test. The usability of the serious game was evaluated with a self-assessment questionnaire. …”
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Construction and validation of a predictive model for poor long-term prognosis in severe acute ischemic stroke after endovascular treatment based on LASSO regression by Yingli Zhang, Yingli Zhang, Yan Guo, Zhenpeng Zhang, Jie Han

“…ObjectiveWe aimed at establishing a predictive model for poor long-term prognosis (3 months post-treatment) following endovascular treatment (EVT) for severe acute ischemic stroke (AIS) and evaluating its predictive performance.MethodsThe patients with severe AIS (NIHSS score ≥ 16) who received EVT were divided into a modeling group (178 patients), an internal validation group (76 patients), and an external validation group (193 patients). …”
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Resting-State Network Dynamics in Asthma: Interplay Between Depressive Symptoms and Airway Inflammation by Maxie Liebscher, Claire Laubacher, Theodore P. Imhoff-Smith, Rasmus M. Birn, Danika R. Klaus, Corrina J. Frye, William W. Busse, Melissa A. Rosenkranz

“…This longitudinal study investigated pre-post changes in graph-theory metrics within and between the 3 networks in individuals with asthma and how these relate to depressive symptoms. …”
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CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life

“…Quality of life was assessed pre- and post-operatively using the SF-36 questionnaire and the Haemophilia Activities List (HAL), focusing on lower limb functions. …”
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Comparison of different auxiliary techniques used during root canal filling removal in terms of the amount of apically extruded debris: In vitro study. by Ismail Uzun, Kevser Şenel, Rawan Alqawasmi

“…During preparation, 15 ml of distilled water was used, followed by 1 ml of distilled water for debris collection post-procedure. The debris was incubated at 68°C for five days to evaporate the water, and tube weights were recorded and compared statistically across groups.…”
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Relation of oncogenic microRNA-10b and microRNA-21 to glioblastoma size and localization by Nikitović Marina, Stepanović Aleksandar, Arsenijević Tatjana, Petrović Nina

“…We analyzed the expression levels of miR-10b and miR-21 post-surgery. The data on tumor size and tumor localization were obtained from magnetic resonance imaging. …”
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First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. by Denise Anderson, Heather J Cordell, Michaela Fakiola, Richard W Francis, Genevieve Syn, Elizabeth S H Scaman, Elizabeth Davis, Simon J Miles, Toby McLeay, Sarra E Jamieson, Jenefer M Blackwell

“…Imputation using the thousand genomes (1000G) reference panel extended the analysis to 6,724,284 post quality-control autosomal SNPs. No associations achieved genome-wide significance, commonly accepted as P<5x10-8. …”
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A 24‐week double‐blind placebo‐controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptom... by Katy Bernard, Sylvie Gouttefangeas, Sylvie Bretin, Stéphanie Galtier, Philippe Robert, Vjera Holthoff‐Detto, Jeffrey Cummings, Maria Pueyo

“…An improvement on neuropsychiatric symptoms assessed by NPI was evidenced at the lower dose 5 mg/d (Δ ‐2.55, P = .023, post hoc analysis) compared to placebo. CSDD and total NPI scores improved in all groups including placebo. …”
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Impact of left ventricular end-diastolic pressure on clinical outcomes in patients with ST-elevation myocardial infarction (Hunter LVEDP Study): a prospective, single-centre study by John Attia, Nicholas Collins, Mohammed S Al-Omary, Andrew J Boyle, Max Ray, Arshad A Khan, Trent Williams, Jonah Taylor

“…Objectives Elevated left ventricular end-diastolic pressure (LVEDP) in ST-segment elevation myocardial infarction (STEMI) has been studied in patients who received thrombolysis or who were treated early in the primary percutaneous coronary intervention (PCI) era; LVEDP was found to be a predictor of adverse outcomes in these retrospective post hoc analyses. The aim of the current analysis is to assess the prognostic value of the elevated LVEDP in STEMI patients undergoing primary PCI in current contemporary practice.Design Prospective, single-centre study.Participants Our study enrolled STEMI patients with elevated LVEDP undergoing primary PCI at John Hunter Hospital, Newcastle, Australia.Primary outcome measure The primary endpoint was the combination of 12-month all-cause mortality and heart failure admissions, comparing different quartiles of LVEDP.Results A total of 997 patients underwent primary PCI at our hospital during the 5-year study period (age: 64±13 years, males: 73%; n=728) from 1 January 2015 to 31 December 2019. …”
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Hurricanes and turbulent floods threaten arsenic-contaminated coastal soils and vulnerable communities by Layla N. Izadi, Amin Tamadoni, Matthew G. Siebecker, Piyapas Sricharoenvech, Matheus S.C. Barreto, Matthew H.H. Fischel, Ryan Tappero, Donald L. Sparks

“…We found that arsenic speciation on resuspended particles is closely tied to shear stress, with As(V) prevailing at low stress and the more toxic As(III) dominating at higher stress levels. In the post-erosion phase, solid-phase As(III) decreased while dissolved As(III) increased, indicating ongoing desorption. …”
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Dynamiques socio-politiques et territorialités de l’immigration ivoirienne en Tunisie by Camille Cassarini

“…Indeed, many Ivorians justify their departure for Tunisia by the change in regime that followed the post-election crisis of 2011. By mobilising the register of ethnicity and their exclusion from the political game, these people expressed, in their mobilities, the structural changes to Ivorian society over the last twenty years. …”
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Predicting Early Treatment Effectiveness in Bell&rsquo;s Palsy Using Machine Learning: A Focus on Corticosteroids and Antivirals by Luo JT, Hung YC, Chen GJ, Lin YS

“…Outcomes, defined as full resolution of symptoms, were assessed using the House-Brackmann scale at 3 and 9 months post-treatment. We employed six different machine learning models to predict recovery outcomes and evaluated model performance using AUC, precision, recall, and F1-score.Results: Among 493 patients, 72.6% recovered after three months and 89.5% after nine months. …”
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Gastrointestinal Cancers with Consideration of DPD and UGT1A1 Plasma Levels: Chemotherapy-Related Toxicity by Velko Minchev, Hristo Tsankov, Bozil Robev, Martin Takov, Stefan Federchev, Kalina Kamenova, Lozan Todorov, Liliya Atanasova, Nadya Hristova-Avakumova, Rumen Nikolov, Pavlina Gateva, Vanyo Mitev

“…Univariable and bivariable analyses and a general linear model (GLM) framework were used. Post-infusional reductions in white blood cell and granulocyte counts were observed. …”
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The effect of the displacement pressure on migration of fluid during the imbibition for tight oil reservoir by Yubin Yang, Xian Peng, Wenlian Xiao, Qihong Lei, Tao Li, Youan He, Chun Zhang, Jiahao Jiang, Tao Qi, Lingli Zheng, Haoyu Chen

“…During this process, initial pressure—specifically the shut-in pressure post-fracturing—plays a crucial role in ensuring imbibition recovery and determining shut-in duration. …”
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The Effect of Google Sites-assisted Flipped Classroom Discovery Learning Model and Cognitive Style on Mathematics Problem-Solving Skills and Student Learning Independence by Muhammad Albar, Siti Masitoh, Andi Kristanto, Widyawanti Rajiman

“…The data were gained through pretests and post-tests conducted on students to measure their problem-solving skills and learning independence. …”
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RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors by Shenghua Dong, Junjie Pang, Yushuai Wang, Le Han, Xiaoxiao Zhou, Feng Huang, Subo Zhang, Ning Ma, Huilin Huang, Hengyou Weng

“…The switch of m6A readers coordinates chromatin remodeling and post-transcriptional regulation to drive lung endoderm specification. …”
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Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program. by Allison E Ashley-Koch, Nathan A Kimbrel, Xue J Qin, Jennifer H Lindquist, Melanie E Garrett, Michelle F Dennis, Lauren P Hair, Jennifer E Huffman, Daniel A Jacobson, Ravi K Madduri, Hilary Coon, Anna R Docherty, Jooeun Kang, Niamh Mullins, Douglas M Ruderfer, VA Million Veteran Program (MVP), MVP Suicide Exemplar Workgroup, International Suicide Genetics Consortium, Philip D Harvey, Benjamin H McMahon, David W Oslin, Elizabeth R Hauser, Michael A Hauser, Jean C Beckham

“…The genetic correlation of SI and SA within MVP was high (rG = 0.87; p = 1.09e-50), as well as with post-traumatic stress disorder (PTSD; rG = 0.78; p = 1.98e-95) and major depressive disorder (MDD; rG = 0.78; p = 8.33e-83). …”
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Peri-implant bone behavior after single drilling technique versus undersized drilling technique of immediately loaded implant in posterior maxilla: a one-year prospective study by Mohamed Ahmed Galal Sadek, Mohamed Zaghlool Amer, Nesma El-Gohary, Heba Abo-Elfetouh Elsheikh

“…Conclusion Both techniques revealed comparable, promising clinical and radiographic outcomes over a 12-month post-loading follow-up period when the immediate loading protocol was used in the posterior maxilla, where bone density is poor, but preparing the implant bed using the single drilling technique offers several merits for both the patient and clinician. …”
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Long-term treatment outcomes of spinal intradural tumors: A 10-year cohort study in Zenica-Doboj Canton by Haso Sefo, Hakija Bečulić, Rasim Skomorac, Fahrudin Alić, Emir Begagić, Ermin Hadžić, Mirza Pojskić

“…Patients underwent neurological examinations and spinal magnetic resonance imaging scans, followed by post-surgery assessments at 3 and 6 months using the McCormick scale. …”
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