The Accuracy of Dynamic Parameters for Prediction of Fluid Responsiveness in Elderly Patients with Septic Shock by Paphawin S, Theerawit P, Junhasavasdikul D, Sutherasan Y

“…MAP responsiveness was defined as a ≥ 10% increase in MAP post-fluid loading. Receiver operating characteristic curves were constructed to assess predictive parameters such as PPV, SVV for fluid responsiveness, and Eadyn for MAP response after loading. …”
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Early prediction of histopathological response of locally advanced rectal cancer after 1 week of preoperative radiochemotherapy using 18FDG PET-CT imaging: a prospective clinical v... by Yulia Kundel, Zoya Cohen, Noa Gordon, Aaron Sulkes, Sara Morgenstern, Gali Perl, Nir Wasserberg, David Groshar, Hanna Bernstine, Baruch Brenner

“…Conclusions A decrease in SUVmax after 1 week of nRCT for LARC failed to predict the achievement of pCR or TRG in the post-nRCT surgical specimen, underlining the importance of validation clinical trials. …”
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Does local vaginal estrogen after tension-free transobturator vaginal tape reduce overactive bladder symptoms in postmenopausal women? A prospective randomized, controlled study by Samer Mahmoud Morsy, Dalia Farouk, Sara Hassan, Ahmed Yehia Abdelaziz, Hussein Aly Hussein

“…All patients had to fulfill a 3-day bladder diary, overactive bladder symptoms score, urine analysis, urodynamic study, and post-voiding residual urine measurement by abdominal ultrasound preoperatively and at 3-month and 6-month follow-ups. …”
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Assembly of MSCs into a spheroid configuration increases poly(I:C)-mediated TLR3 activation and the immunomodulatory potential of MSCs for alleviating murine colitis by Chao-Ting Ho, Ying-Chi Kao, Yueh-Ming Shyu, I-Ching Wang, Qiao-Xuan Liu, Shao-Wen Liu, Shih-Chen Huang, Han Chiu, Li-Wen Hsu, Tzu-Sheng Hsu, Wan-Chen Hsieh, Chieh-Cheng Huang

“…Conclusion Collectively, these findings highlight the synergistic benefits of combining 3D spheroid assembly with TLR3 activation as an innovative strategy to improve the therapeutic efficacy of MSC-based treatments for IBD and other inflammatory diseases by increasing post-engraftment cell survival and immunomodulatory capacity.…”
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Impact of the conflict interactions and social learning on the hierarchy structure in captive males of Moschus chrysogaster (Moschidae) by Xiaolong Wang, Jiayi Wu, Xiaoping Lu, Vasili Shakun, Irena Solovej, Xiuxiang Meng

“…In addition, we found a significant surge in socially learning behaviours among musk deer post-conflict, indicative of the essential spread of information on individual rank and fighting capabilities within the captive population. …”
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Liver metastases in thyroid cancer: epidemiology, risk stratification and survival outcomes in the immunotherapy era by Ming-Lu Xu, Yang-Yang Wang, Li-Ping Xie, Ning Ding, Jia-Jun Hui

“…No statistically significant difference in mOS and median cancer-specific survival (mCSS) of these patients between the pre- and post-immunotherapy eras were observed (P>0.05 for both).ConclusionThis study establishes the first population-based predictive framework for liver metastases in thyroid cancer, underscoring risk stratification and survival. …”
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Vaccination with a low dose of BCG or BCG∆BCG1419c protects against short-term Mycobacterium tuberculosis HN878 infection in male CB6F1 mice by Jorge Barrios-Payán, Cristian A. Segura-Cerda, Dulce Mata-Espinosa, Helle Bielefeldt‑Ohmann, Rogelio Hernández-Pando, Mario A. Flores-Valdez

“…Material and methods: In this study, we explored the efficacy of vaccination with a low dose (102 CFUs) of BCG or BCGΔBCG1419c against Mtb HN878 infection in male CB6F1 mice, both at the short-term (1 month) and chronic (3 months post-infection) stages of active TB. Results: Vaccination with a low dose of BCG or BCGΔBCG1419c provided protection against Mtb HN878 challenge only 1 month after infection. …”
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Clinical characteristics and factors associated with severe COVID-19 among hospitalized pediatric patients: a retrospective cohort study in the Chaoshan region of China by Xianyao Wang, Ruiling Ma, Ruiling Ma, Wenshan Zhong, Haipeng Lin, Hachao Zhou, Zhiwei Xiao, Shaofen Lin, Yutao Guo, Xufeng Zheng, Mingxiang Lin

“…Despite the decreased viral transmissibility and pathogenicity observed in the post-pandemic era, identifying early clinical indicators for severe pediatric COVID-19 remains crucial.MethodA retrospective cohort study analyzed 287 hospitalized pediatric COVID-19 patients admitted from December 2022 to August 2023. …”
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Age at puberty and risk of asthma: A Mendelian randomisation study. by Cosetta Minelli, Diana A van der Plaat, Bénédicte Leynaert, Raquel Granell, Andre F S Amaral, Miguel Pereira, Osama Mahmoud, James Potts, Nuala A Sheehan, Jack Bowden, John Thompson, Debbie Jarvis, George Davey Smith, John Henderson

“…., genetic variants were used as instrumental variables to estimate causal effects of early puberty on post-pubertal asthma in both females and males.<h4>Methods and findings</h4>MR analyses were performed in UK Biobank on 243,316 women using 254 genetic variants for age at menarche, and on 192,067 men using 46 variants for age at voice breaking. …”
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Balloon-occluded versus conventional transarterial chemoembolization for the treatment of early to intermediate stage hepatocellular carcinoma: a meta-analysis and trial sequential... by Jiaxi Liu, Weiwei Wang, Huan Zhai, Yanan Ma, Qiwen You, Haibo Shao

“…In terms of AEs, only post-embolization syndrome was found to occur more frequently in patients treated with B-TACE than in those treated with cTACE (RR = 1.30, 95% CI 1.01–1.68, p = 0.04). …”
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El entrenamiento a intervalos de alta intensidad no mejora el balance autonómico en cuarentenas por COVID-19 by Héctor Fuentes Barría, Sebastián Urbano Cerda, Raúl Aguilera Eguía, Valentina Vera Aguirre, Catalina González Wong

“…<br /><strong>Resultados:</strong> se reportaron cambios medios significativos pre y post evaluación en baja frecuencia (p = 0,009; d = 0,18), alta frecuencia (p = 0,009; d = 0,18) y SD1 (p = 0,007; d = 0,18), mientras que en su relación no se reportaron cambios significativos (p = 0,113; d = 0,16). …”
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Risk Factors of Ankle Sprain in Soccer Players: A Systematic Review and Meta-Analysis by Amir Human Hoveidaei, Amir Reza Moradi, Amin Nakhostin-Ansari, Mohammad Mehdi Mousavi Nasab, Seyed Pouya Taghavi, Shayan Eghdami, Bijan Forogh, Masumeh Bagherzadeh Cham, Christopher J. Murdock

“…ASI can lead to chronic ankle instability, obesity, and post-traumatic osteoarthritis. This study focuses on identifying factors such as gender, age, body mass index (BMI), and a history of ASIs, which contribute to the development of ASI in soccer players. …”
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Global context-aware attention model for weakly-supervised temporal action localization by Weina Fu, Wenxiang Zhang, Jing Long, Gautam Srivastava, Shuai Liu

“…The existing WTAL methods lack the ability to distinguish the action context information effectively, including the pre-action and post-action scenes, which blur the action boundary and lead to the inaccurate action location. …”
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Targeted delivery and controlled release of polymeric nanomedicines for tumor therapy by Na Shen, Weidong Zhao, Hongyu Chu, Haiyang Yu, Hai Sun, Zhaohui Tang, Xuesi Chen

“…Despite these advances, clinical outcomes indicate that the overall survival rates of cancer patients post-treatment are often not significantly higher than those achieved with standard small-molecule drugs. …”
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Fast-RF-Shimming: Accelerate RF shimming in 7T MRI using deep learning by Zhengyi Lu, Hao Liang, Ming Lu, Xiao Wang, Xinqiang Yan, Yuankai Huo

“…Finally, we design Non-uniformity Field Detector (NFD), an optional post-processing step, to ensure the extreme non-uniform outcomes are identified. …”
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Identifying commonalities and differences between EHR representations of PASC and ME/CFS in the RECOVER EHR cohort by John P. Powers, Tomas J. McIntee, Abhishek Bhatia, Charisse R. Madlock-Brown, Jaime Seltzer, Anisha Sekar, Nita Jain, Mady Hornig, Elle Seibert, Peter J. Leese, Melissa Haendel, Richard Moffitt, Emily R. Pfaff, On behalf of the N3C Consortium and RECOVER-EHR

“…Abstract Background Shared symptoms and biological abnormalities between post-acute sequelae of SARS-CoV-2 infection (PASC) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) could suggest common pathophysiological bases and would support coordinated treatment efforts. …”
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Developing an objective framework for scrub nurse training: A Japanese pilot study by Keita Ishido, Minami Tsukada, Rina Tazawa, Saseem Poudel, Akitaka Motoyoshi, Zen Naito, Satoshi Hirano

“…Two novice scrub nurses participated in a pilot study involving 26 surgical procedures, during which real-time intra-operative instruction and post-procedure feedback were delivered using SCOPE. …”
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Effect of a Bacillus-based probiotic on fecal shedding and cecal colonization of Salmonella Enteritidis in laying hens by I. Poudel, A. Calvert, A.S. Kiess, L. Zhang, P.A. Adhikari

“…Fecal samples were collected on 3-, 7- and 14-days post inoculation (dpi). Cecal contents were collected aseptically on 7 and 14 dpi. …”
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Analisis Perbedaan Hasil Produksi ASI dan Status Gizi Ibu Menyusui sebelum dan setelah Konsumsi Food Bar Tepung Daun Katuk (Sauropus Androgynus) dan Daun Torbangun (Coleus Amboinic... by Dinda Karlina, Nanang Nasrullah, Dian Luthfiana Sufyan

“…Metode: Quasi Experimental pre dan post test without control. Penelitian dilakukan selama 4 hari. …”
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Surgical removal of subretinal cysticercosis in conjunction with administration of intravenous methylprednisolone: A case report by Amrit Banstola, Sachin Iyer, Amir Akhavanrezayat, Tanya Jain, Muna Kharel, Ankur Sudhir Gupta, Jia-Horung Hung, Woong-Sun Yoo, Quan Dong Nguyen, Anadi Khatri

“…She was diagnosed with subretinal cysticercosis and underwent pars plana vitrectomy with in toto removal of the cyst along with pre/post-surgical intravenous methylprednisolone and anti-parasitic medications. …”
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