Dentinal tubule penetration of sodium hypochlorite in root canals with and without mechanical preparation and different irrigant activation methods by Renata Aqel de Oliveira, Theodoro Weissheimer, Gabriel Barcelos Só, Ricardo Abreu da Rosa, Matheus Albino Souza, Rodrigo Gonçalves Ribeiro, Marcus Vinicius Reis Só

“…One-way analysis of variance, followed by the Tukey post hoc test, and the Student’s t-test were used for data analysis, with a significance level of 5%.ResultsThe NaOCl penetration depth was similar when preparation was performed, regardless of the method of irrigation activation (p > 0.05). …”
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Dam‐Induced Alternations of Flow and Sediment Regimes in the Tibetan Plateau: An Example of the Yarlung Tsangpo River by Dongmei Zhao, Kunlong He, Donghong Xiong, Xixi Lu, Xiaomin Qin, Xiaodan Wang, Wenduo Zhang

“…Specifically, sediment reduction was notable under dam regulation on both the mainstem and tributary, with a moderate alteration degree of 45.34%, particularly during the main flood and post‐flood seasons. Dominant sediment periodicities at annual and semi‐annual scales were nearly eliminated, while flow periodicities were preserved. …”
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Passage of Angiostrongylus cantonensis through the trophic web: an experimental study on reptiles by Lucia Anettová, Anna Šipková, Vivienne Velič, Jana Kačmaříková, Kristýna Javorská, Ladislav Novotný, Petr Cibulka, Martin Květoň, David Modrý

“…Snakes were euthanized 1 month post-infection and live L3 were detected predominantly in the intestinal wall. …”
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MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosis by Debmalya Mitra, Gabriel K. Armijo, Elizabeth H. Ober, Shenda M. Baker, Helen C. Turner, Constantinos G. Broustas

“…Male C57BL/6J adult mice were exposed to 13 Gy partial body X–irradiation with 5% bone marrow shielding and MIIST305 was administered on days 1, 3, and 5 post-irradiation. Approximately 85% of the animals survived the irradiation exposure and were apparently healthy until the end of the 30-day study period. …”
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First record of methicillin-resistant Staphylococcus aureus (MRSA) isolated from the Meia Ponte River and effluent in Brazil: an analysis of 1198 isolates by Igor Romeiro dos Santos, Leandro Fonseca de Lima, Marcelino Benvindo de Souza, Isabela Náthaly Machado da Silva, Adriano Roberto Vieira de Sousa, Alexandre Melo Bailão, Cátia Lira do Amaral, Elisa Flávia Luiz Cardoso Bailão

“…Effluent samples were collected at two points in the STP (pre- and post-treatment). Surface water was collected at six points along the Meia Ponte River, from its source to the mouth. …”
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Longitudinal Overlap and Metabolite Analysis in Spectroscopic MRI-Guided Proton Beam Therapy in Pediatric High-Grade Glioma by Abinand C. Rejimon, Anuradha G. Trivedi, Vicki Huang, Karthik K. Ramesh, Natia Esiashvilli, Eduard Schreibmann, Hyunsuk Shim, Kartik Reddy, Bree R. Eaton

“…Longitudinal analyses included voxel-level metabolic change maps and spatial overlap metrics comparing pre-proton therapy and post-. Results: Six patients had sufficient longitudinal data; five received sMRI-guided PBT. …”
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A Hidden Threat: A Case Report on Pheochromocytoma in a Horse (Equus ferus caballus) by Romelia Pop, Valeria Ciulu-Angelescu, Maria Popescu, Otilia Bulmez, Denisa Bungărdean, Mirela Alexandra Tripon, Zsofia Daradics, Alexandru Florin Lupsan, Iancu Morar, Cristian Crecan, Dragoș Hodor, Claudiu-Nicușor Ionică, Ecaterina Semzenisi, Alexandru-Flaviu Tăbăran

“…Pheochromocytomas, though often diagnosed post-mortem, can cause life-threatening cardiovascular and systemic effects, underscoring the importance of histopathological evaluation and the need for improved antemortem diagnostic techniques in equine practice. …”
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Rebuilding lives in Nagaya, a public housing for older victims of the great East Japan earthquake: An interview survey by Naomi Ito, Yurie Kobashi, Yuri Kinoshita, Nobuaki Moriyama, Toshiki Abe, Hiroaki Saito, Isamu Amir, Chika Yamamoto, Mika Sato, Masaharu Tsubokura

“…In summary, this study emphasizes the critical role of communities in post-disaster recovery and proposes new perspectives for supporting older adults in such contexts.…”
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Improving trans-regional hydrological modelling by combining LSTM with big hydrological data by Senlin Tang, Fubao Sun, Qiang Zhang, Vijay P. Singh, Yao Feng

“…New hydrological insights for the region: The results demonstrate that a post-processing scheme combining deep learning, meteorological data, and GHMs significantly improves model accuracy, achieving a median Nash-Sutcliffe Efficiency (NSE) of 0.64, compared to 0.50 for the baseline Long Short-Term Memory (LSTM) model without GHMs. …”
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Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups by Qi Wang, Jie Liu, Zi-Dan Zhou, Ke-Xin Zhou, Fei Li, Qi-Wen Zhang, Shou-Kai Wang, Wei Wang, Zhen Jin, You-Zhi Tang

“…Furthermore, compound 13 was further studied by the time-killing kinetics and the post-antibiotic effect approach. In the mouse thigh infection model, compound 13 exhibited superior antibacterial efficacy than that of tiamulin. …”
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Suppress or Not to Suppress … CRAFT It: A Targeted Metabolomics Case Study Extracting Essential Biomarker Signals Directly from the Full ¹H NMR Spectra of Horse Serum Sa... by James Chen, Ayelet Yablon, Christina Metaxas, Matheus Guedin, Joseph Hu, Kenith Conover, Merrill Simpson, Sarah L. Ralston, Krish Krishnamurthy, István Pelczer

“…In addition, there are no pre/post processing steps (such as baseline and/or phase), further minimizing potential dependency on subjective decisions by the user and providing an opportunity to automate the entire process. …”
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Discerning Genes to Deliver Varieties: Enhancing Vegetative- and Reproductive-Stage Flooding Tolerance in Rice by Sanchika Snehi, Kt Ravi Kiran, Sanket Rathi, Sameer Upadhyay, Suneetha Kota, Satish Kumar Sanwal, Bm Lokeshkumar, Arun Balasubramaniam, Nitish Ranjan Prakash, Pawan Kumar Singh

“…The ability to tolerate stagnant flooding can be ascribed to several adaptive traits: accelerated aerenchyma formation, efficient underwater photosynthesis, reduced radial oxygen loss in submerged tissues, reinforced culms, enhanced reactive oxygen species scavenging within cells, dehydration tolerance post-flooding, and resistance to pests and diseases. …”
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Identification of an immune-suppressed subtype of feline triple-negative basal-like invasive mammary carcinomas, spontaneous models of breast cancer by Elie Dagher, Laura Simbault, Jérôme Abadie, Delphine Loussouarn, Mario Campone, Frédérique Nguyen

“…One hundred and eighty female cats with feline invasive mammary carcinomas, treated by surgery only, with 2-year follow-up post-mastectomy, were included in this study. Forkhead box protein P3, estrogen receptor, progesterone receptor, Ki-67, epidermal growth factor receptor type 2, and cytokeratin 14 expression were assessed by automated immunohistochemistry. …”
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Longitudinal Study of Hepatitis A Infection by Saliva Sampling: The Kinetics of HAV Markers in Saliva Revealed the Application of Saliva Tests for Hepatitis A Study. by Luciane Almeida Amado Leon, Adilson José de Almeida, Vanessa Salete de Paula, Renata Santos Tourinho, Daniel Antunes Maciel Villela, Ana Maria Coimbra Gaspar, Lia Laura Lewis-Ximenez, Marcelo Alves Pinto

“…The present study followed-up ten patients with acute hepatitis A infection during 180 days post diagnosis (dpd). Total anti-HAV was detected in paired serum and saliva samples until the end of the follow-up, showing a peak titer at 90th. …”
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Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications by Zhang Cheng, Li-Jie Wang, Yuchi Honaker, Steven A. Cincotta, Claire E. Page, Sydney Vollhardt, Victor Yuan, S. Alice Long, Yuanyuan Xiao, Joshua N. Beilke, Joseph R. Arron, Jeffrey A. Bluestone

“…By systematically profiling Treg and effector T cells (Teff) pre- and post-expansion, we defined the molecular fingerprints for expanded Treg products. …”
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Peritoneal dialysis catheter insertion in patients with obesity: a cohort study and single centre approach to increasing uptake by Walker Andrew, Corr Michael, Conroy Daniel, McDaid James, McGrogan Damian, Fogarty Damian, O’Neil Stephen

“…Laparoscopic and percutaneous catheter insertion techniques were used, and primary outcomes included catheter patency (primary, primary assisted, secondary) and infection rates (exit site infection, tunnel infection, peritonitis) 1-year post-insertion. Kaplan-Meier survival analysis and descriptive statistics were applied to compare outcomes between groups. …”
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SGLT2 inhibitor use and renal outcomes in low-risk population with diabetes mellitus and normal or low body mass index by Hye Ryoun Jang, Jung Eun Lee, Wooseong Huh, Yun Soo Lee, Goeun Park, Kyungho Lee, Junseok Jeon

“…Introduction Recent post hoc analyses indicate that patients with normal or low body mass index (BMI) benefit from sodium-glucose cotransporter-2 (SGLT2) inhibitor use. …”
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Inactivated vaccines derived from bovine viral diarrhea virus B3 strain elicit robust and specific humoral and cellular immune responses by Ming-Guo Xu, Ao-Di Wu, Jing-Nan Liu, Zhong-Lian Yang, Hong-Huan Li, Hai-Long Ma, Ning-Ning Yang, Ning-Ning Yang, Jin-Liang Sheng, Chuang-Fu Chen

“…BALB/c mice were immunized, and immune responses were assessed via ELISpot, ELISA, and virus neutralization assays. On day 42 post-immunization, the mice were challenged with BVDV, and the viral loads were quantified.ResultsThe vaccines showed stable characteristics and sterility and are suitable for immunization studies. …”
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Palmitoylation regulators drive the progression of clear cell renal cell carcinoma through Inhibition of cuproptosis: insights into the role of ZDHHC18 by Wei Xu, Xiao-chao Chen, Yang Wang, Jian-chun Chen, Zhi-jun Cao, Ru Huang, Chao Chen, Dao-rong Hou, Min-jun Jiang, Chen Xu

“…Abstract Background Protein palmitoylation is a reversible post-translational modification that increases protein hydrophobicity, which can affect protein localization, stability, and function. …”
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Evaluation of the Effect of Saudi Coffee Consumption in Comparison to Various Types of Coffees on the Color of Novel Aesthetic Dental Ceramics by Ghada O. Alrabeah, Abdullatif A. AlGhazzi, Naif H. AlOtaibi, Ali N. AlAnzan, Khalid F. AlOtaibi

“…Data were analyzed using paired sample t-test and one-way ANOVA and post hoc testing. Color coordinates L*, a* and b* significantly changed after immersion in all coffee solutions relative to pre-immersion values, with a noticeable decrease in lightness (L*) (P < .05). …”
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