Effect of monochromatic light on self-renewal and differentiation of intestinal stem cells in broilers by Xinlei Tao, Ge Hu, Zixu Wang, Yaoxing Chen, Jing Cao

“…This study examines the effects of monochromatic light on the self-renewal and differentiation of ISC, thereby elucidating the mechanisms by which monochromatic light influences the growth and development of broilers. The post-hatching day 0 (P0) Cobb 500 broilers were randomly assigned to white light (WL), red light (RL), green light (GL) and blue light (BL) until P35. …”
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Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages by S. Rossi, C. Di Filippo, C. Gesualdo, N. Potenza, A. Russo, M. C. Trotta, M. V. Zippo, R. Maisto, F. Ferraraccio, F. Simonelli, M. D’Amico

“…RvD1 was administered into the right eye at a single injection of 5 μL volume containing 10–100–1000 ng/kg RvD1 1 h post-LPS injection (200 μg, Salmonella minnesota) into thefootpad of Sprague-Dawley rats. 24 h later, the eye was enucleated and examined for clinical, biochemical, and immunohistochemical evaluations. …”
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Prognostic impact of neutrophil-to-lymphocyte ratio (NLR) in patients with unresectable biliary tract cancer treated with gemcitabine, cisplatin, and durvalumab by Satoshi Mii, Hiroyuki Kato, Takeshi Takahara, Masayuki Kojima, Yutaro Kato, Zenichi Morise, Akihiko Horiguchi, Koichi Suda

“…Half of the patients had recurrence post-surgery, and many of them had previously received chemotherapy. …”
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System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance by Jan Sebek, Tej B. Shrestha, Matthew T. Basel, Faraz Chamani, Nooshin Zeinali, Ivina Mali, Macy Payne, Sarah A. Timmerman, Pegah Faridi, Marla Pyle, Martin O’Halloran, M. Conall Dennedy, Stefan H. Bossmann, Punit Prakash

“…HAC15 tumors implanted in nude mice (n = 6) were ablated in vivo and monitored with MRIT in multiple planes. One day post ablation, animals were euthanized, and excised tumors were processed for viability assessment.Results Average absolute error between temperatures from fiberoptic sensors and MRIT was 0.6 °C across all ex-vivo ablations. …”
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Comparative Clinico‐Haematological Alterations of Lumpy Skin Disease Affected Cattle at Different Ages and Periods of Disease in Bangladesh by Md. Saiful Islam Siddiqui, Md. Ashiqur Rahman, Saiful Islam, Papri Rani Dey, Md. Khademul Islam, Sultana Begum, Md. Masudur Rahman

“…The control and affected cattle were categorized into four age groups consisting of nine cattle (Group A = under 1 year; Group B = 1 to 2 years; Group C = 2 to 3 years; and Group D = from 4 years up to 10 years) in each group and three disease periods of post infection (prodromal period, period of illness and period of decline) consist of each of 12 LSD affected cattle. …”
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Characterization of Aspergillus oryzae mutant and its application in heterologous lipase expression by Qinghua Li, Chen Zhang, Jianghua Li, Guocheng Du, Zhaofeng Li, Jingwen Zhou, Guoqiang Zhang

“…The Aspergillus oryzae expression system has been developed into a chassis for the production of heterologous lipases, attributed to its strong capabilities in protein production and secretion, robust post-translational modifications, and favourable safety profile. …”
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Exploring METRNL as a novel biomarker in sepsis: diagnostic potential and secretion mechanism by Tian-Ying Xu, Jing-Xin Zhao, Ming-Yao Chen, Zhu-Wei Miao, Zhi-Yong Li, Yong-Qing Chang, Yu-Sheng Wang, Chao-Yu Miao

“…In animals, serum METRNL increased within 1 h post-modeling, preceding PCT and CRP. Clinically, sepsis patients had significantly higher serum METRNL levels. …”
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Preventing suicide with Safe Alternatives for Teens and Youths (SAFETY): a randomised feasibility trial by David Mataix-Cols, Oskar Flygare, Joan Rosenbaum Asarnow, Johan Bjureberg, Clara Hellner, Jennifer L Hughes, Gergö Hadlaczky, Ralf Kuja-Halkola, Moa Ponten, Moa Karemyr, Martin Bellander, Anna Ohlis, Ylva Walldén

“…Primary endpoint was 3-month post-treatment. Feasibility outcomes included treatment and assessment compliance, adverse events, treatment credibility and treatment satisfaction. …”
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The effect of neuromuscular blocking reversal agents on perioperative neurocognitive function after general anaesthesia: a systematic review and meta-analysis by Hao Wang, Xinghua Lv, Lin Wu, Fangli Ma, Ling Wang, Yongqi Wang, Xiaoxia Wang, Yulan Li

“…The primary outcome was the incidence of PND within 7 days following surgery, while the secondary outcomes included the time required to achieve a Train-of-Four ratio (TOF) ≥ 0.9 after administration of NMBRs, length of stay (LOS) in both the post-anaesthesia care unit (PACU) and the hospital, as well as the risk of adverse events (i.e. postoperative nausea and vomiting (PONV) and mortality). …”
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Optimizing ERAS protocols in robotic nephron-sparing surgery: a randomized trial by Yiqiang Wang, Mangmang He, Lulu Lou

“…GCQ scores improved significantly in the ERAS group post-intervention (p < 0.001). Conclusion ERAS nursing grounded in evidence-based medicine significantly enhances postoperative recovery, reduces complications, and improves patient comfort in robotic-assisted partial nephrectomy. …”
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Pre-formation loading of extracellular vesicles with exogenous molecules using photoporation by Jana Ramon, Cláudio Pinheiro, Charysse Vandendriessche, Estefanía Lozano-Andrés, Herlinde De Keersmaecker, Deep Punj, Juan C. Fraire, Edward Geeurickx, Marca H. M. Wauben, Pieter Vader, Roosmarijn E. Vandenbroucke, An Hendrix, Stephan Stremersch, Stefaan C. De Smedt, Koen Raemdonck, Kevin Braeckmans

“…., during EV biogenesis), offers advantages compared to post-formation loading (i.e., after EV isolation), as EV integrity and composition are minimally perturbed. …”
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A longitudinal mixed methods social network analysis to evaluate a peer-led housing program for older men returning from incarceration: Study protocol & pre-implementation results by Brandy F. Henry, Derek A. Kreager, Joy Gray, Kristina Brant, Gary Zajac, Divine Lipscomb, Sarah Brothers, David R. Schaefer, Nicolette Bardele, Andrea Hazelwood

“…To evaluate program impacts for long-term health and social outcomes, we use an untreated matched sample to compare 6- and 12-months post-prison release outcomes using administrative data related to rearrest/reincarceration and behavioral health. …”
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Immunomarker profiling in human chronic wound swabs reveals IL-1 beta/IL-1RA and CXCL8/CXCL10 ratios as potential biomarkers for wound healing, infection status and regenerative st... by Julian-Dario Rembe, Waseem Garabet, Matthias Augustin, Joachim Dissemond, Wiebke Ibing, Hubert Schelzig, Ewa K. Stuermer

“…Abstract Background Chronic wounds, such as diabetic foot ulcers, venous leg ulcers, and post-surgical wound healing disorders pose a significant challenge due to prolonged healing, risk of infection, and impaired quality of life. …”
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Assessment of war-induced agricultural land use changes in Ukraine using machine learning applied to Sentinel satellite data by Nataliia Kussul, Andrii Shelestov, Bohdan Yailymov, Hanna Yailymova, Guido Lemoine, Klaus Deininger

“…The consistently high accuracy of our classification methodology across the nine-year study period demonstrates its robustness and suitability for long-term monitoring of agricultural dynamics in conflict-affected regions and provides a valuable tool for guiding post-war recovery efforts. Our findings underscore the importance of leveraging satellite data for timely and accurate land use monitoring, supporting policymakers in addressing food security challenges and promoting sustainable agricultural practices. …”
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Association between lifestyle, multiple chronic conditions, mental health status and the severity of lower urinary tract symptoms/benign prostatic hyperplasia in Chinese elderly by Yifan Wu, Yifan Wu, Yuwei Zhang, Yuwei Zhang, Xinwei Liu, Xinwei Liu, Yongneng Huang, Yongneng Huang, Ye Hua, Ninghan Feng, Ninghan Feng

“…After adjusting for confounders (such as age, disease duration, prostate volume, total prostate-specific antigen, C-reactive protein, post-voided residual urine, urea nitrogen, etc.), current smoking (OR = 1.995, 95%CI:1.270–3.134), unhealthy dietary habits (OR = 1.590, 95%CI: 1.059–2.386), and lack of active exercise (OR = 1.996, 95%CI:1.274–3.127) were positively correlated with the severity of BPH/LUTS. …”
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Two-dimensional modeling of nitrate transport in canola field under Moistube irrigation using HYDRUS 2D/3D by Tinashe Lindel Dirwai, Tinashe Lindel Dirwai, Aidan Senzanje, Aidan Senzanje, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi, Tafadzwanashe Mabhaudhi

“…Soil samples were collected both adjacent to and 15 cm away from MTI laterals at multiple depths before and at 2 h, 4 h, 24 h, 48 h, and 72 h post-fertigation. HYDRUS 2D/3D was used to simulate solute transport, while nitrogen use efficiency was evaluated using the partial factor productivity of applied nitrogen (PFPN).ResultsThe 55% ETc regime showed the highest nitrate leaching, followed by the 75% ETc regime. …”
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An accelerated hypofractionated radiotherapy regimen in patients after organ-sparing surgery for stages I–IIA breast cancer by I. A. Gladilina, L. Ya. Klepper, Yu. V. Efimkina, I. V. Vysotskaya, A. V. Petrovskiy, O. V. Kozlov, M. V. Chernykh, E. Yu. Voronchikhina, E. S. Makarov, A. V. Ivanova

“…The 6-year relapse-free survival rates in patients who had received the accelerated hypo-fractionated radiotherapy regimen were also significantly higher than in those who had the standard radiotherapy regimen: 97.9 and 71.3 %, respectively (p ≤ 0.043). The rate of post-radiation normal tissue damages after the hypofractionated radiotherapy regimen was significantly lower (15.2 %) than that after the standard regimen (27.5 %). …”
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Advances in stem cell therapy for erectile dysfunction: preclinical evidence and emerging therapeutic approaches by Xiaoliang Fu, Azar Sheikholeslami, Ulanbek Zhanbyrbekuly, Faezeh Davoodi Asl, Nadiar M. Mussin, Hoda Fazaeli, Karim Daniyalov, Nader Tanideh, Nader Tanideh, Nader Tanideh, Mahdi Mahdipour, Mahdi Mahdipour, Madina A. Kurmanalina, Amin Tamadon, Amin Tamadon, Amin Tamadon

“…Even though phosphodiesterase type 5 inhibitors (PDEi) and other conventional therapies have demonstrated efficacy, they frequently prove insufficient for patients with underlying medical disorders such as diabetes, Peyronie’s disease, or post-prostatectomy. This review delves into the therapeutic capacity of stem cells for ED, emphasizing the latest clinical and preclinical studies that showcase their efficacy across various models. …”
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The efficacy and safety of antithrombotic therapy in patients undergoing TAVI: a network meta-analysis by Jingxian Han, Keyao Liu, Yuxin Li, Dong Han, Pengchong Liang, Ningjun Zhao, Shuqun Hu, Xianliang Yan

“…Transcatheter aortic valve implantation (TAVI) has emerged as a transformative therapy, especially for patients at high or intermediate surgical risk. However, the optimal post-TAVI antithrombotic therapy remains a subject of debate due to the need to balance thromboembolic prevention with bleeding risks. …”
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Sex differential impact of comorbidities in spondyloarthritis: data from COMOSPA study by Maxime Dougados, Anna Molto, Jordi Gratacós, Clementina López-Medina, Mireia Moreno, Maria Llop, Marta Arevalo Salaet, Joan Calvet, Antoni Berenguer-Llergo

“…Objectives To describe and compare the prevalence of comorbidities in female and male patients with spondyloarthritis (SpA) and to assess whether comorbidities had a different impact on disease outcomes in male and female patients.Methods This is a post hoc analysis of the COMOrbidities in SPondyloArthritis study. …”
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