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27001
Dapagliflozin-Induced Acute Pancreatitis: A Case Report and Review of Literature
Published 2020-01-01“…A 51-year-old male with a history of type 2 diabetes, dyslipidemia, and status-post cholecystectomy presented to the emergency room with a four-day history of periumbilical pain radiating to the back. …”
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27002
Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis
Published 2025-07-01“…Here we identify microglial connexin43 (Cx43) hemichannels as a regulator of microglial reactivity in AD, positioning them as a promising therapeutic target. Post-mortem AD patient tissue showed elevated Cx43 levels in periplaque microglia. …”
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27003
Mejora de las actitudes hacia las matemáticas y la autoeficacia docente con Aprendizaje-Servicio y Gamificación
Published 2025-06-01“…El estudio se realizó a través de un diseño cuasiexperimental con medidas pre/post tratamiento de las variables fundamentales. …”
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27004
Supporting mothers of discharged premature infants: a clinical trial on tele counseling for self-efficacy and anxiety management
Published 2025-07-01“…Abstract Background Premature birth and hospitalization in the neonatal intensive care unit (NICU) can stress mothers and impact their self-efficacy post-discharge. This study aimed to assess the effects of tele counseling and an educational pamphlet on the self-efficacy and anxiety of these mothers. …”
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27005
Fermentation of Sainfoin Seed Flour with <i>Saccharomyces boulardii</i>: Effects on Total Dietary Fiber, Anti-Nutrients, Antimicrobial Activity, and Bioaccessibility of Bioactive C...
Published 2025-06-01“…Antimicrobial activity against <i>Escherichia coli</i> ATCC 25922 improved after fermentation, while the antioxidant capacity was enhanced post-digestion. In addition, the highest phenolic content (612 mg GAE/100 g) and antioxidant capacity (1745 mg TE/100 g by CUPRAC assay and 1127 mg TE/100 g by DPPH assay) were determined in fermented sainfoin seed flour at 72 h after gastrointestinal digestion.…”
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27006
Efficacy of hemoadsorption in the severe course of COVID-19
Published 2025-03-01“…The goal of the current study is to evaluate the clinical efficacy of hemoadsorption with mesoporous hypercrosslinked polystyrene beads (Efferon CT single-use cartridge) in an expanded cohort of patients with severe and critical COVID-19 resistant to antibody therapies and requiring post-therapy invasive mechanical lung ventilation (MLV) versus parameter-matched control group with no hemoadsorption.Materials and methodsA single-center cohort study (NCT06402279) enrolled patients from October 2020 to February 2022: the Efferon CT group (non-responders to anti-cytokine antibody therapy requiring IMV, hemadsorption, and standard treatment, n = 65) and retrospectively acquired propensity-matched control group (no hemadsorption, standard treatment only, n = 65).ResultsThis observational study revealed the capability of Efferon CT hemoadsorption to safely, rapidly, and significantly reduce the need for norepinephrine, increase the oxygenation index, prevent the sepsis-associated AKI, decrease the development of multiorgan failure, and restore the immune system balance by decreasing pro-inflammatory IL-6, ferritin levels, and neutrophil-to-lymphocyte ratio.ConclusionThe clinical efficiency of hemoadsorption using Efferon CT was confirmed by the resolution of acute respiratory failure in 54% of patients, significantly increasing the number of days without mechanical ventilation and increasing early the index of oxygenation. …”
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27007
Sociocultural pressures and appearance ideal internalization: Their impact on body dissatisfaction in Brazilian adults
Published 2025-08-01“…Statistical analyses involved non-parametric tests (Kolmogorov-Smirnov, Mann-Whitney U, Kruskal-Wallis, Dunn's post hoc tests) and Spearman's correlation, with a significance level set at p < .05. …”
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27008
Interface Alterations in Cellulose Synthases Redefine CESA Complex Assembly to Enhance Cellulosic Biomass Production
Published 2025-07-01“…Our findings indicate that CESA gene duplication and interface residue divergence, coupled with tissue‐specific and environment‐dependent expression and post‐translational modifications, drive CSC diversification. …”
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27009
Association between cancer-associated fibroblasts and prognosis of neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma: a bioinformatics analysis based on single-ce...
Published 2025-03-01“…Conclusion Our findings highlight the dynamic alterations in the post-NCRT ESCC microenvironment and provide a foundation for the development of personalized treatment and immunotherapeutic approaches. …”
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27010
Insight on Efficacy of Renal Artery Denervation for Refractory Hypertension with Chronic Kidney Diseases: A Long-Term Follow-Up of 24-Hour Ambulatory Blood Pressure
Published 2022-01-01“…To explore the long-term efficacy and safety of renal denervation in patients with RHT and CKD, a post hoc analysis of eGFR subgroups was completed. …”
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27011
Potential for circular economy in the construction sector. An explorative study about single-use masks and sustainable building material based on a customer and construction compan...
Published 2025-07-01“…Practical implications recommend the development of partnerships between companies and research institutions, in order to bring the testing and application side together as well as the necessity of research in material science and (post- use) processing.…”
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27012
Impact of restoration thickness and tooth shade background on the translucency of zirconia laminate veneers: An in vitro comparative study
Published 2024-01-01“…Data were analyzed using ANOVA and post hoc Tukey’s test (p < 0.05). Results: The translucency values were optimal for the veneers placed over the substrate teeth with shades A1 and A2, regardless of the veneer thickness. …”
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27013
Aneurysmal degeneration after drug-eluting stent implantation in lower limb arteries: A systematic review and case reports
Published 2025-09-01“…Objectives: To systematically review the incidence, anatomical distribution, mechanisms, and clinical outcomes of aneurysmal degeneration following implantation of paclitaxel-eluting stents in lower limb arteries, define its incidence, anatomical distribution, proposed mechanisms, diagnostic criteria, and therapeutic approaches and to present a representative case requiring open surgical revision 12 months post-Eluvia implantation. Methods: A PRISMA-compliant systematic review was performed including randomized trials, observational studies, and case reports describing aneurysmal degeneration after DES implantation. …”
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27014
Furosemide Reduces Radionuclide Activity in the Bladder in <sup>18</sup>F-PSMA-1007-PET/CT: A Single-Center Retrospective Intra-Individual Comparative Study
Published 2025-07-01“…Images were acquired 60 min post-injection of 250 MBq of tracer activity. Standardized Uptake Values (SUVmax, SUVpeak, SUVmean) were measured in the bladder and in tissues with physiological uptake by three readers. …”
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27015
Observational Study on Progressive Muscle Relaxation and Breathing Control for Reducing Dental Anxiety in Children
Published 2025-05-01“…Dental anxiety was measured with the Romanian-validated IDAF-4C<sup>+</sup>, and physiological stress was measured via blood pressure and heart rate. Pre and post-intervention data were analyzed using paired <i>t</i>-tests, ANOVA, and cluster analysis. …”
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27016
Improvement of Fasting Glucose in Response to Resistance Training with Emphasis on the Expression of Hepatic PGC1α and HNF4α Genes in Type 2 Diabetic Rats
Published 2025-06-01“…Forty-eight hours following the prolonged exercise session, hepatocytes genes PGC1α and HNF4α expression, along with serum insulin, glucose, and insulin resistance, was analyzed using One-Way ANOVA and Tukey post hoc test across different groups. Results: T2D induction led to significant decrease in insulin levels and an increase in fasting glucose, alongside increased insulin resistance and hepatocytes genes PGC1α and HNF4α expression when compared to non-diabetes rats. …”
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27017
White Suit, Black Notebooks: (Un)Disclosed Diaries of Bronislaw Malinowski and Martin Heidegger
Published 2025-06-01“…As part of a report, which was written by the commander of a trading post in Central Congo, Mr. Kurtz, upon request from “International Society for the Suppression of Savage Customs” (49), this literary phrase directly reflects a very real colonial attitude toward indigenous people and their customs, the “inferior races,” one that also included enslavement, physical punishment, mutilation, and killing (Lindquist ix-x). …”
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27018
Human Cervical Intervertebral Disc Pressure Response During Non-Injurious Quasistatic Motion: A Feasibility Study
Published 2025-05-01“…This feasibility study aimed to implement the use of pressure sensors in whole-body post-mortem human subject (PMHS) cervical spine intervertebral discs (IVDs) to confirm the feasibility and repeatability of cervical IVD pressure response to biomechanic research. …”
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27019
Analysis of prevalence, aetio-pathology of tinnitus and role of caroverine as a primary treatment option among the patients attending a tertiary care hospital
Published 2025-07-01“…Detailed clinical evaluation, audiometric testing, and Tinnitus Handicap Inventory (THI) scoring were performed at baseline and post-treatment. Caroverine was administered for 6 weeks. …”
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27020
Incidence of acute kidney injury-associated mortality in hospitalized children: a systematic review and meta-analysis
Published 2025-03-01“…Subgroup analyses showed no significant differences across geographical regions, income levels, or AKI definition criteria. The pooled post-discharge mortality rate was 6.84% (95% CI: 5.86, 7.82) in a 1–9-year follow-up period. …”
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