Analysis Strategy for Identifying the <i>O</i>-Linked Glycan Profile and <i>O</i>-glycosylation Sites on Recombinant Human Follicle Stimulating Hormone-<i>C</i>-terminal Peptide (r... by Xinyue Hu, Yuxing Xiang, Xiaoming Zhang, Yue Sun, Yi Li, Lvyin Wang, Ping Lv, Zhen Long, Chenggang Liang, Jing Li

“…<i>O</i>-glycosylation is a common post-translational modification on extracellular and secreted proteins driving biochemical and biophysical interactions at the cell surface. …”
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Integrated analysis of microRNA and mRNA interactions regulating fecundity in the ovaries of two distinct sheep breeds by Salsabeel Yousuf, Waqar Afzal Malik, Hui Feng, Tianyi Liu, Lingli Xie, Xiangyang Miao

“…MicroRNAs (miRNAs) are crucial post-transcriptional regulators of gene expression, binding to target messenger RNAs (mRNAs) to inhibit translation or trigger degradation. …”
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Upper gastrointestinal bleeding differences between older and younger adults: should bleeding in non-cirrhotic patients be considered a geriatric syndrome? by Francisco Vara-Luiz, Ivo Mendes, Carolina Palma, Paulo Mascarenhas, Diogo Simas, Plácido Gomes, André Ruge Gonçalves, Inês Simão, Madalena Teixeira, Sara Ramos Lopes, Francisca Côrte-Real, Maria Antónia Duarte, Catarina Bravo, Marta Patita, Gonçalo Nunes, Pedro Pinto-Marques, Jorge Fonseca

“…Overall mortality was 15% ( n  = 90), with 76 deaths attributed to non-bleeding causes. In a post hoc subgroup analysis excluding cirrhotic patients, older adults required hospitalization ( p  = 0.007) and longer hospital stays ( p  = 0.005) more frequently, while younger patients had higher intensive care unit admission rates ( p  = 0.018). …”
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Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system by Jiaqi Chen, Zhuoying He, Wenjuan Xu, Yumiao Kang, Fengyu Zhu, Heng Tang, Jianye Wang, Fei Zhong

“…However, challenges such as stem cell loss and immune phagocytosis post-transplantation hinder their application. Due to easy and safe handling, in vitro ovarian culture is widely available for drug screening, pathophysiological research, and in vitro fertilization. …”
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Exploring tolerance and side effects of an innovative yeast-bound iron supplement: a feasibility trial by Keely A. Shaw, Thomas A. Tompkins, Brendan Abrahamson-Durant, Gillian MacNevin, Jill A. Parnell, Martin J. MacInnis, Raylene A. Reimer, Jane Shearer

“…Qualitative data on supplement acceptability were collected post-intervention. Feasibility was evaluated based on recruitment, retention, adherence, and safety criteria. …”
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Prolonged allograft survival in liver transplantation by Yash Kadakia, MD, Andrew D. Shubin, MD, PhD, Malcolm MacConmara, MBBCh FACS, Madhukar S. Patel, MD, MBA, ScM, Jorge A. Sanchez-Vivaldi, MD, Lauren E. Matevish, MD, Steven I. Hanish, MD, FACS, Parsia A. Vagefi, MD, FACS, Christine S. Hwang, MD, FACS

“…Methods: Using the UNOS STARfile, allografts with a cumulative age (sum of age at transplant plus post-transplant survival) of octogenarian, 90–99 nonagenarian, and 100 years or greater (centurion) were identified from all adult transplant recipients between 1990 and 2022. …”
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Neutrinos from Carbon-burning Red Supergiants and Their Detectability by Gwangeon Seong, Kyujin Kwak, Dongsu Ryu, Bok-Kyun Shin

“…We first calculate the luminosity and energy spectrum of the neutrinos emitted during the post-main-sequence evolution of massive stars. For a nearby carbon-burning RSG located  ∼200 pc away, we estimate the neutrino flux reaching Earth to be as large as  ∼10 ^5 cm ^−2 s ^−1 , with a spectrum peaking at ∼0.6 MeV. …”
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Online Education Research in the Islamic World: A Bibliometric Systematic ‎Review by Hasan Mahmoud Abu Hasna, Fatima Saleh Al Blooshi

“…The insights gained from this review offer a foundation for future research and practice in integrating online education in the Islamic world, aiming to enhance educational practices and outcomes in the post-pandemic world.…”
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Luteolin-Rich Extract from <i>Harrisonia perforata</i> (Blanco) Merr. Root Alleviates SARS-CoV-2 Spike Protein-Stimulated Lung Inflammation via Inhibition of MAPK/NLRP3 Inflammasom... by Warathit Semmarath, Punnida Arjsri, Kamonwan Srisawad, Sonthaya Umsumarng, Pornngarm Dejkriengkraikul

“…The COVID-19-related long-standing effect or Post-Acute Sequelae of COVID-19 (PASC) is often associated with NLRP3 inflammasome activation in pulmonary inflammation elicited by SARS-CoV-2 spike proteins. …”
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Monitoring osseointegration and degradation of Mg-alloy implants through plasma biomarkers of inflammation and bone regeneration by Eduarda Mota-Silva, Diana C. Martinez, Giuseppina Basta, Serena Babboni, Serena del Turco, Davide Fragnito, Stefano Salvadori, Claudia Kusmic, Leon Riehakainen, Daniele Panetta, Beatrice Campanella, Massimo Onor, Tomasz Plocinski, Wojciech Swieszkowski, Luca Menichetti

“…A total of 16 biomarkers were measured from plasma samples collected at multiple timepoints up to 90 days post-implantation. Mg-alloy, Ti-alloy, and Sham (noncritical bone defect) groups were followed with computed tomography, histological, and SEM-EDX analysis. …”
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Characterisation and Harnessing of 5‐Hydroxymethylfurfural Metabolism in Pseudomonas umsongensis GO16 for the Production of 2,5‐Furandicarboxylic Acid by Rhys Orimaco, Pauric Donnelly, Seán Sexton, Aoife McLoughlin, Sophie Kelly, Kevin E. O'Connor, Nick Wierckx, Tanja Narančić

“…This expands the repertoire of valuable products obtained from engineered P. umsongensis GO16 in the strategy to bio‐upcycle post‐consumer PET.…”
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Adverse socioeconomic factors are associated with a widening gap in one-year health-related quality of life after acute myocardial infarction by David Füller, Henrike Andresen-Bundus, Nikolaos Pagonas, Philipp Jaehn, Christian Ukena, Kathrin Gödde, Christine Holmberg, Oliver Ritter, Benjamin Sasko

“…Patients with lower educational attainment were more likely to report dyspnea at hospital admission, had a worse renal function and more frequently hypertension. One year post-AMI the health state of the cohort worsened in terms of the mobility, activity, pain, and anxiety/depression domains but not the self-care domain. …”
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MÁS ALLÁ DE LA MEMORIZACIÓN: UN ACERCAMIENTO AL PENSAMIENTO CRÍTICO DESDE LAS AULAS by Norberto López

“…De esta manera, el sujeto activo del conocimiento aprende mediante la reflexión para participar de un proceso dialógico en la construcción colectiva de nuevos saberes, desarrollando a su vez el análisis de las realidades sociales para ser una agente del cambio en post de las democracias deliberativas.   …”
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Tolerable limits of fecal coliforms in the conservation of vacuum-packed beef stored at 0° C by María Deisy Camacho-Rioja, Jorge Asfura-Telchi, Cinthia Huarachi-Chirilla

“…For this purpose, a measurement was made 48 h post mortem in 3 pH ranges: <5.8, 5.9 and 6 to 7 to quantify Escherichia coli and mesophilic aerobes. …”
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Parents’ experiences of family-based physical activity interventions: a systematic review and qualitative evidence synthesis by Carol Brennan, Evangeline Streight, Shishi Cheng, Ryan E. Rhodes

“…Conclusions This novel and comprehensive review offers practical recommendations to guide intervention development and inform future policy and practice such as: consider using co-design methods and social network analysis; promoting the benefits of PA on family functioning during recruitment; strengthening parents PA support identities; provide opportunities for social support for families post-intervention and educate coaches to create an environment of inclusivity and enjoyment. …”
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Emergence delirium in small animals: a first step towards an objective assessment by Larissa Irina Mattei, Ludovica Chiavaccini, Claudia Spadavecchia, Alessandro Mirra, Alessandro Mirra

“…Phase 3: no association between subject or anesthesia related factors and the occurrence of ED was found in the univariable analysis.ConclusionBased on the proposed list of symptoms, post anesthetic ED seems to occur frequently in small animals. …”
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Headache in Patients with Cervical Spondylotic Myelopathy by Shoji Yabuki, Kozue Takatsuki, Koji Otani, Takuya Nikaido, Kazuyuki Watanabe, Kinshi Kato, Hiroshi Kobayashi, Jun-ichi Handa, Shinichi Konno

“…Kruskal–Wallis tests with Dunn–Bonferroni post hoc tests were used for comparisons. Results. …”
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Identification and analysis of miRNA - mRNA regulatory modules associated with resistance to bacterial leaf streak in rice by Baowei Wu, Xiaoyu Zhang, Jialiang Zhao, Bohong Zeng, Zhibin Cao

“…By conducting miRNA sequencing and transcriptome sequencing on both Dular and 9311 before and after BLS inoculation, we identified 19 miRNAs that were significantly downregulated at both 12 and 24 h post-inoculation in Dular, and 9 miRNAs that were significantly upregulated at the same time points in 9311. …”
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Cytokine responses to the anti-schistosome vaccine candidate antigen glutathione-S-transferase vary with host age and are boosted by praziquantel treatment. by Claire D Bourke, Norman Nausch, Nadine Rujeni, Laura J Appleby, François Trottein, Nicholas Midzi, Takafira Mduluza, Francisca Mutapi

“…Participant age and pre-treatment infection status significantly influenced post-treatment cytokine profiles.<h4>Conclusions/significance</h4>In areas where schistosomiasis is endemic host age, schistosome infection status and PZQ treatment affect the cellular cytokine response to GST. …”
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Diagnosing schizophrenia with routine blood tests: a comparative analysis of machine learning algorithms by Yavuz Selim Ogur, Ayse Erdogan Kaya, Nur Banu Ogur, Beyza Erdogan Akturk

“…Following optimization, Random Forest accuracy improved (94.95%) with a recall of 96.25%, while XGBoost reached the highest accuracy (95.90%) and strong specificity (95.54%). Post-optimization, Area Under the Curve (AUC) values were highest for XGBoost (0.96) and Random Forest (0.95), indicating strong diagnostic performance. …”
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