Varus alignment of the hip and knee 2 years after anterior cruciate ligament injury is associated with medial tibiofemoral osteoarthritis 3 years later by Henrik Nilsson, Martin Englund, Richard Frobell, L. Stefan Lohmander, André Struglics, Per Swärd

“…Level of Evidence Level II exploratory post hoc analysis of an RCT.…”
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Impact of potassium management on soil dynamics and crop uptake in rice systems by Suchismita Mohapatra, Kumbha Karna Rout, Chandramani Khanda, Amit Mishra, Sudhir Yadav, Sudhir Yadav, Rajeev Padbhushan, Ajay Kumar Mishra, Sheetal Sharma

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Integrative GWAS and transcriptomics reveal GhAMT2 as a key regulator of cotton resistance to Verticillium wilt by Long Wang, Long Wang, Long Wang, Yonglin Yang, Jianghong Qin, Qifeng Ma, Kaikai Qiao, Shuli Fan, Yanying Qu

“…Transcriptomic profiling revealed that GhAMT2 was significantly upregulated at 12 hours post-inoculation with V. dahliae, coinciding with the activation of immune signaling pathways. …”
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Ultra-high-resolution imaging of intracranial flow diverters with photon counting CT: A comparative phantom study with flat-panel CT by Christoph Johannes Maurer, Ansgar Berlis, Dmitrij Pinekenstein, Michael Wolf, Gebhard Östreicher, Lars Behrens, Franz Josef Stangl

“…PCD-CT at a CTDIvol of 10 mGy offered the best balance between image quality and radiation dose, making it a viable alternative for post-interventional assessment of flow diverters.…”
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464 Loading of the medial knee ligaments and anterior cruciate ligament during clinical tests of anteromedial rotatory instability by Andrew Pechstein, Erin Berube, Mark Amirtharaj, Emma Reznick, Thomas Wickiewicz, Paul Christos, Carl Imhauser

“…The in situ force (N) in the sMCL, dMCL, POL, and ACL at the peak applied load for each loading condition was calculated using superposition and compared with Kruskal–Wallis tests with post hoc pairwise testing using a Bonferroni–Holm correction for multiple comparisons (α = 0.05). …”
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Evaluation of Brain Function Recovery After Traumatic Brain Injury Treatment in a Porcine Model by Cross-Group Temporal–Spatial Correlation Analysis by Wenwu Sun, William Reeves, Madison M. Fagan, Christina B. Welch, Kelly M. Scheulin, Sydney E. Sneed, Todd R. Callaway, Kylee J. Duberstein, Franklin D. West, Qun Zhao

“…This study underscores the effectiveness of the methodology in evaluating post-TBI treatments such as the FMT. By presenting comprehensive experimental and simulated data, our research contributes significantly to the field and opens new paths for future investigations into TBI treatment evaluations.…”
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Physiological and psychological determinants of cardiovascular autonomic response in experienced Cold-Water Swimmers by Josefa Lillo Bobadilla, Aline Fieldhouse Sandoval, Pedro Fernández Fredes, Paula Bravo Sepúlveda, Matías Castillo-Aguilar, Michele Macedo Moraes, Thiago Teixeira Mendes, Cristian A. Núñez Espinosa

“…Participants were assessed at four key time points: baseline, pre-dive, post-dive, and recovery. Cardiovascular parameters, heart rate variability (HRV), and psychological states were measured using validated tools. …”
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Addressing loneliness in emerging adults in primary care: a pilot feasibility study by Kris Pui Kwan Ma, Brennan Keiser, Melissa Garcia, Chialing Hsu, Karina Cortez, Ashley Johnson, Ajla Pleho, Mary C. Curran, Kelly Schloredt, Kwun C. G. Chan, Kari A. Stephens, Sebastian T. Tong

“…Results from paired T-tests showed pre-post reductions in loneliness, depression, and anxiety for both CBT and SP interventions, though they were statistically non-significant. …”
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The effects of a large-scale nature-based solution on the macroinvertebrate diversity in a gravel river in The Netherlands by Maya M. Daumal, Rosan van Halsema, Dorine T.B.M. Dekkers, Roy H.J. Erkens, Edwin T.H.M. Peeters

“…We propose five lessons for future NbS planning: conduct thorough system analysis, gather pre- and post-project data, set ecologically realistic goals, implement adaptive management, and promote knowledge sharing. …”
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Retrospective Analysis of Sacubitril/Valsartan vs Benazepril for Treating Heart Failure Following Acute Myocardial Infarction by Zhao L, Ren Y, Qin D, Yang X, Chen Z, Zhang N

“…The incidence of adverse reactions was comparable between the two groups (P > 0.05).Conclusion: Sacubitril/Valsartan is a safe and effective treatment for heart failure post-AMI, offering significant improvements in cardiac function, inflammatory response, exercise capacity, and a reduction in MACE risk.Keywords: sacubitril/valsartan, heart failure following acute myocardial infarction, efficacy, cardiac function…”
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Molecular modelling and gene expression analysis to probe the GT-γ trihelix transcription factors in Solanum tuberosum under drought stress by Tayyaba Bint Tariq, Faiza Munir, Ishrat Jabeen, Alvina Gul, Rabia Amir

“…Physicochemical analysis highlighted differences in protein properties that could influence their nuclear function. Post-translational modifications further diversified their functionalities. …”
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Microscopic intramural spread in patients with rectal cancer after neoadjuvant chemoradiation by A.E. Verrijssen, E.J. Van Limbergen, M. Bellezzo, H.I. Grabsch, R. Houben, D. Goudkade, J. Melenhorst, I. Samarska, G. Paiva Fonseca, F. Verhaegen, M. Berbee

“…Conclusions: 69% of patients do not retain MIS post-neoadjuvant therapy. Knowledge of tumor thickness seems crucial for patient selection for CXB.…”
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Sleep quality among clinical postgraduate students: a cross-sectional study in Kerala, India by Gopinathan Bhaskaran Gopika, GK Mini, Ameer Ameera, R. Parvathi, P. K. Malavika, Reshma George, Kamala Swarnam, Marthanda Pillai A

“…Those who were having severe stress were more likely to report poor sleep quality compared to their counterparts (adjusted odds ratio (AOR):11.61, CI:1.35–99.39). Medical post graduates were more likely to report poor sleep quality compared to the surgical specialty (AOR: 2.27, CI:1.06–4.87). …”
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Feasibility study protocol: implementing consultation-based high-quality palliative care services in intensive care units by Shin Hye Yoo, Ye Sul Jeung, Yejin Kim, Seyeon Kim, Yoon Sun Jung, Tae Jung Kim

“…The intervention’s potential impact will be assessed by changes in surrogate decision-making conflict, self-efficacy, depression and anxiety, post-decision regret and the experience of patient-centred and family-centred care. …”
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The relationship between hair cortisol and trauma sequelae in motor vehicle crash survivors: the role of childhood trauma experiences by Ileana Schmalbach, Susann Steudte-Schmiedgen, Vanessa Renner, Philipp Drees, Katja Petrowski

“…PDS and IES-R were re-collected three months post-MVC (t2). Elevated pre-MVC HCC predicted PTSD symptoms (p < 0.05), emphasizing the role of chronic stress and HPA axis dysregulation in PTSD. …”
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CORRECTION OF PSYCHONEUROLOGICAL SIGNS OF ACUTE ALCOHOL INTOXICATION IN RATS WITH A NEW ACETYLCYSTEINE-BASED COMPOSITION by D. V. Kurkin, E. I. Morkovin, N. A. Osadchenko, D. A. Bakulin, E. E. Abrosimova, M. A. Dubrovina, N. S. Kovalev, Yu. V. Gorbunova, I. N. Tyurenkov

“…The study was conducted on male Wistar rats. The post-intoxication state was simulated by a single injection of ethanol (3 g/kg, intraperitoneally). …”
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Prevalência dos tipos de fissura em pacientes com fissuras labiopalatinas atendidos em um Hospital Pediátrico do Nordeste brasileiro Prevalence of kinds of cleft lip and palate at... by Moacir Cymrot, Felipe de Castro Dantas Sales, Francisco de Assis Alves Teixeira, Francisco de Assis Alves Teixeira Junior, Geraldo Sérgio Barbosa Teixeira, José Ferreira da Cunha Filho, Natália de Holanda e Oliveira

“…A higher prevalence of trans-incisive foramen cleft in males and post-incisive foramen cleft in girls was observed.…”
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Frequency of periodontal disease in head and neck cancer patients after radiation therapy: a cross-sectional study by Asmaa Abou-Bakr, Enji Ahmed, Hany William, Fatma E. A. Hassanein

“…Conclusions The frequency of periodontitis in the studied sample of HNC patients post RT was 95.08%, reflecting a notably high burden. …”
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Impact of glibenclamide pretreatment on outcomes in acute ischemic stroke patients with type 2 diabetes: a retrospective case-control study by Kaimin Xiao, Ji Tang, Xinwei Yang, Hongmei Chen, Ping Liu, Rongxin He, Lihui Xie, Heling Chu, Yuping Tang, Li Chen

“…Glibenclamide pretreatment in patients with acute ischemic stroke and T2DM may confer clinical benefits by reducing stroke severity and enhancing post-stroke functional outcomes, without increasing adverse events.…”
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Effects of high-intensity multimodal functional training on motor and cognitive functions in people with multiple sclerosis: A study protocol of a pilot randomized controlled trial by Rebecca Cardini, Rita Bertoni, Ilaria Carpinella, Chiara Pegorini, Andrea Tacchino, Erica Grange, Valentina Guidotti, Giampaolo Brichetto, Claudio Solaro, Tommaso Budassi, Tatiana Lanfranco, Marco Rovaris, Davide Cattaneo, Elisa Gervasoni

“…Participants will undergo an extensive evaluation at baseline (T0), post-intervention (T1), and after 2 months at the follow-up (T2). …”
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