Metabolomics analysis uncovers metabolic changes and remodeling of anti-VEGF therapy on macular edema by Congcong Yan, Quanyong Yi, Lina Ge, Ying Huang, Chun Yang, Bing Lin, Dan Jiang, Meng Zhou

“…Results Distinct metabolomic profiles were observed between pre- and post-treatment samples. A total of 145 significantly altered metabolites were identified after anti-VEGF treatment, with 84 upregulated metabolites related to carbohydrate and amino acid metabolism, and 61 downregulated metabolites involved in amino acid metabolism. …”
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Water-enhanced CO2 capture in metal–organic frameworks by Celine Cammarere, Jaeden Cortés, T. Grant Glover, Randall Q. Snurr, Joseph T. Hupp, Jian Liu, Jian Liu

“…CO2 capture from post-combustion flue gas originating from coal or natural gas power plants, or even from the ambient atmosphere, is a promising strategy to reduce the atmospheric CO2 concentration and achieve global decarbonization goals. …”
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The Effect of Prophylactic Hepatoprotective Therapy on Drug-Induced Liver Injury in Patients Undergoing Chemotherapy for Cervical Cancer: A Retrospective Analysis Based on Propensi... by Zhe Liu, Dongliang Yuan, Jun Chang, Lei Shi, Jingmeng Li, Mei Zhao, Qi Yang

“…However, the number of patients experiencing an increase in their grade of liver injury was significantly higher in the treatment group (18.10% vs. 13.40%, <i>p</i> = 0.002), with these patients also exhibiting increased levels of alkaline phosphatase (ALP) and direct bilirubin (DBIL) post-chemotherapy (<i>p</i> < 0.05). Hepatoprotective drugs are not associated with a reduced risk of DILI and may in fact increase risk.…”
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Running Subcuticular Sutures Versus Simple Interrupted Suture in Wound Healing of Fibroadenoma Patients: A Randomised Control Trial by Dhirendra Nath Choudhury, Bibhu Priyo Das, Bibhu Priyo Das, Eeshan Chakraborty

“…Objectives: To compare wound healing in post-operative patients of fibroadenoma when skin closure is done with running subcuticular suture as compared to simple interrupted suture. …”
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Effect of different remineralizing agents on the initial carious lesions – A comparative study by Mohammed Alhamed, Faisal Almalki, Ahmad Alselami, Tariq Alotaibi, Wahdan Elkwatehy

“…A one-way ANOVA test was used to compare DIAGNOdent scores among the three groups. Post- Hoc Tukey test was used to determine the significant difference between every two groups. …”
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Effect of neuromeningeal mobilization and postural re-education exercises for persistent hamstring strain: a case report by Praveen Kumar Kandakurti, Ramprasad Muthukrishnan, Watson Arulsingh, Animesh Hazari

“…Similarly, the pre- and post-intervention Knee Society score improved from 22 to 61 in pain and from 30 to 80 in function. …”
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Loratadine disrupts cardiovascular and swim bladder development in zebrafish by Xiuyan He, Wenji Hu, Yao Zu

“…In this study, zebrafish embryos were exposed to loratadine (35–350 μg/L) to evaluate its developmental effects. By 2–3 days post-fertilization (dpf), exposed larvae exhibited marked cardiac defects, including pericardial edema, reduced heart rate and cardiac output, and fractional area change (p < 0.05). …”
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Effects of milk fat globule membrane ingestion with exercise on physical strength in healthy young adults: a randomized double-blind, placebo-controlled trial by Kyosuke Nakayama, Kyoko Ito, Yoshihiko Minegishi, Noriyasu Ota, Shukuko Ebihara, Chiaki Sanbongi

“…An analysis of covariance (ANCOVA) model with baseline values as a covariate was carried out to test differences in post intervention values between groups.Results Ingestion of MFGM significantly improved peak torque (p = 0.003) and average power (p = 0.019) of isokinetic knee extensors, leg press 1 repetition maximum (RM) (p = 0.004) and sit-ups reps (p = 0.030), but not indicators of agility, compared with placebo after the 4-week intervention. …”
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Different action of glucocorticoid receptor in adipose tissue remodelling to modulate energy homeostasis by chronic restraint stress by Yinghua Luo, Qinyu Liu, Yaqian Mao, Junping Wen, Gang Chen

“…A fasting control group was included for comparison. Post-stress assessments included behavioural tests, glucose and insulin tolerance tests and indirect calorimetry. …”
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Hurricanes lead to declines in taxonomic, phylogenetic, and functional richness and shifts in moth community composition by Aura M. Alonso‐Rodríguez, Pablo E. Gutiérrez‐Fonseca, Ingi Agnarsson, Catherine M. Hulshof, Scott E. Miller, Taylor H. Ricketts

“…In addition, the hurricanes altered both taxonomic and phylogenetic composition, with smaller grass‐feeding species increasing in abundance post‐hurricane, while larger arboreal‐feeding species, especially geometrid moths, declined markedly. …”
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Heart rate and heart rate variability in lambs, measured by biologgers, during transport and its relationship to basal cortisol concentration by Isabella Manenti, José A. Abecia, Irene Viola, Paola Toschi, Francisco Canto, Silvia Miretti

“…Saliva samples for cortisol measurements were collected 24 h and 4 h before transport and 1 h post-transport. Based on basal cortisol concentrations, lambs were assigned to one of two groups, low cortisol (LC) or high cortisol (HC). …”
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Number of previous cesarean deliveries and its effects on outcomes of vaginal hysterectomy by Hyesook Kim, Hye-yon Cho, Sung Taek Park, Sung-ho Park

“…Surgical outcomes, including surgery time, postoperative hospital stay and drop in hemoglobin level, and estimated blood loss were similar among the three groups. The intra- or post-operative transfusion rate was the highest in the one cesarean delivery group (no cesarean delivery 8.1% vs. one cesarean delivery 20.5% vs. two or more cesarean deliveries 3.3%; p = 0.017). …”
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Improving the efficacy of osteosarcoma therapy: combining drugs that turn cancer cell ‘don't eat me’ signals off and ‘eat me’ signals on by Suchismita Mohanty, Maryam Aghighi, Ketan Yerneni, Johanna Lena Theruvath, Heike E. Daldrup‐Link

“…Twenty‐four mice (n = 6 per group) underwent pre‐ and post‐treatment magnetic resonance imaging (MRI) scans with the macrophage marker ferumoxytol, bioluminescence imaging, and histological analysis. …”
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Protective Effects of Naringenin Against Sodium Arsenite-Induced Hepatic Injury in Mice via Nrf2 Signaling by Nastaran Azarbarz, Yousef Asadi-Fard, Hana Sheykhi, Layasadat Khorsandi

“…The data were then analyzed using one-way ANOVA and Tukey’s post hoc test in SPSS software. Results: SA caused histological damage, characterized by a significant increase in the infiltration of inflammatory cells and the accumulation of red blood cells (P< 0.001). …”
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Fecal Cortisol Metabolites Indicate Increased Stress Levels in Horses During Breaking-In: A Pilot Study by Julia Krieber, Aurelia C. Nowak, Jakob Geissberger, Oliver Illichmann, Sabine Macho-Maschler, Rupert Palme, Franziska Dengler

“…Particularly in the first year under the saddle FCMs were significantly higher than in unridden horses (one way ANOVA + post hoc Holm–Sidak test, <i>p</i> < 0.05), with a tendency for FCM levels to decrease with time in training. …”
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Pengembangan Media Edukasi Kesehatan Berbasis Kesenian Madihin Sebagai Upaya Pencegahan Stunting by Fadhiyah Noor Anisa, Nurul Hidayah, Rusilawati Rusilawati, Melan Yulianti

“…Hasil uji One Way ANOVA didapat p-value=0,007 atau ada perbedaan pengetahuan responden sebelum dan setelah diintervensi Macenting. Hasil uji Post Hoc menunjukkan bahwa terdapat perbedaan pengetahuan responden antara kelompok Macenting berbahasa Banjar dengan kontrol (p-value=0,016) dan kelompok Macenting berbahasa Indonesia dengan kontrol (p-value=0,003), akan tetapi tidak ada perbedaan antara kelompok Macenting berbahasa Banjar dengan berbahasa Indonesia (p-value=0,477). …”
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Prenatal screening of Down syndrome in assisted reproductive techniques pregnancies: A systematic review by Fatemeh Zahra Meamar, Mitra Savabi-Esfahani, Tahmineh Farajkhoda

“…Despite the high psychological burden that false positive results impose on parents, studies that have addressed interpretation of both serum and sonographic markers in both rounds of screening for Down syndrome diagnosis in post-ART pregnancies are limited. Objective: This review study investigated the types of serum screening and imaging for prenatal diagnosis of Down syndrome in ART pregnancies to know and correctly interpret the results of prenatal screenings in these pregnancies. …”
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Comparative Analysis of Pass Go and Traditional Drill Training Methods on Passing Accuracy Development in Youth Football Players Aged 12-15 Years: A Randomized Controlled Trial by Larue Valerio, Fatma Hilal Yagin, Spiridon Plakias

“…Passing accuracy (short-range and medium-range), decision-making, and technical execution were assessed at baseline, mid-intervention, and post-intervention. Results. During a 12-week intervention, the Pass Go methodology group significantly outperformed the drill-based training group in short-range passing accuracy, improving by 24.3% compared to 19.1% (d=1.82, p<0.001), medium-range passing accuracy with increases of 18.7% versus 15.4% (d=1.56, p<0.001), and decision-making speed, achieving a 64.3% improvement against 33.3% (p<0.001). …”
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PENGARUH PEMBERIAN VITAMIN E DALAM MENCEGAH PENURUNAN FUNGSI KOGNITIF VISUOSPASIAL TIKUS YANG TERPAPAR HEAT STRESS by Satria Fadhil Ardika, Ratih Vierda Octaviani, Muyassaroh Muyassaroh

“…Metode: Penelitian eksperimental murni dengan rancangan post-test only controlled group dengan jumlah sampel 21 tikus Sprague Dawley jantan dibagi secara acak menjadi 3 kelompok: kontrol negatif (K1) tidak diberikan paparan heat stress dan vitamin E, kontrol positif (K2) diberikan paparan heat stress 43°C selama 15 menit/hari, perlakuan (P) diberikan vitamin E dengan dosis 0,1 mg/g bb/ hari dengan cara sonde lambung 2 jam sebelum diberikan paparan heat stress 43⁰C selama 15 menit/hari. perlakuan dilakukan selama 14 hari. fungsi kognitif visuospasial diuji dengan Morris Water Maze Test (MWM) selama 5 hari. …”
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Redox Mechanisms Driving Skin Fibroblast-to-Myofibroblast Differentiation by Marzieh Aminzadehanboohi, Manousos Makridakis, Delphine Rasti, Yves Cambet, Karl-Heinz Krause, Antonia Vlahou, Vincent Jaquet

“…H₂O₂ functions as a signalling molecule, regulating various cellular processes mostly through post-translational redox modifications of cysteine thiol groups of specific proteins. …”
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