High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose by Gillian Bonvicini, Sunitha Singh, Lisa Sandersjöö, Tiffany Dallas, Eva Schlein, Amelia D. Dahlén, Sara Lopes van den Broek, Dag Sehlin, Ken G. Andersson, Stina Syvänen

“…In vivo pharmacokinetic analyses of radioiodinated bispecific antibodies and bapineuzumab in brain, blood and peripheral organs were performed over 7 days post-injection in WT mice and a model of Aβ pathology (App NL−G−F ). …”
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A first study of the complex-concentrated-alloy W38Ta36Cr15V11 in Pisces-RF high-flux deuterium plasma by M.T. Vigil, S. Faulhaber, M.I. Patino, A. Založnik, D. Nishijima, M.J. Simmonds, B. Schwendeman, K. Vecchio, G.R. Tynan, M.J. Baldwin

“…Accompanying the compositional change, transient grating spectroscopy analysis, taken pre- and post-plasma exposure on the 1023 K exposed target, revealed ∼30% reduction in surface thermal diffusivity from 9.4×10−6 m2s−1 to 6.7×10−6 m2s−1. …”
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Triagem de Deficiência de Lipase Ácida Lisossômica em uma Unidade Clínica de Dislipidemias by Zenia Brasil, Francisco Antonio H. Fonseca, Marco Antonio Curiati, Sandra Obikawa Kyosen, Vanessa Gonçalves Pereira, Waleria Toledo Fonzar, João Bosco Pesquero, Francy Reis da Silva Patrício, Marcelo Hideki Yamamoto, Joyce Umbelino Yamamoto, Vania D’Almeida, Ana Maria Martins, Maria Cristina Izar

“…Uma criança cuja mãe não realizou o teste teve atividade de LAL indetectável em exame post-mortem. Posteriormente, a mãe e três meio-irmãos tiveram a confirmação de D-LAL. …”
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Systemic lupus erythematosus and risk factors for adverse outcomes in pregnancy: a single center retrospective cohort study in Northern Brazil by Sérgio Henrique Oliveira dos Santos, Juliana Bühring, Luiz Fernando de Souza Passos, Bárbara Seabra Carneiro, Domingos Sávio Nunes de Lima, Sandra Lúcia Euzébio Ribeiro

“…Risk factors for fetal events included the use of acetylsalicylic acid (ASA) during pregnancy (OR=5.22; 95% CI [1.33; 20.54]) and disease activity during pregnancy (OR=1.31; 95% CI [1.14; 1.52]); the use of antimalarials before and during pregnancy was protective (OR=0.14; 95% CI [0.04; 0.44]). According to the post-hoc analysis, the probability of a Type S error in the ASA association was 100%. …”
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Evaluation of the Knowledge and Awareness Level of the Pediatric Residents About the Diagnosis, Treatment and Follow-up of Urinary Tract Infection in Children by Fatma Devrim, Dorukhan Besin, Aslı Kantar Özşahin, Betül Pehlivan Zorlu, Özlem Dur, Ebru Yılmaz, Nida Dincel

“…Considering this, we believe it will be good to keep the knowledge updated concerning the treatment and follow-up of children with urinary tract infection through in-service training and post-graduate education. …”
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Novel Sonoguided Digital Palpation and Ultrasound-Guided Hydrodissection of the Long Thoracic Nerve for Managing Serratus Anterior Muscle Pain Syndrome: A Case Report with Technica... by Nunung Nugroho, King Hei Stanley Lam, Theodore Tandiono, Teinny Suryadi, Anwar Suhaimi, Wahida Ratnawati, Daniel Chiung-Jui Su, Yonghyun Yoon, Kenneth Dean Reeves

“…The patient reported immediate pain relief post-procedure, with the pain reducing from 9/10 to 1/10 on the Numeric Rating Scale (NRS), and sustained relief and functional improvement at the 12-month follow-up. …”
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Evaluation of an organic diet intervention to reduce pesticide exposure: a repeated measures cross-over study among rural and urban communities in Selangor, Malaysia by Vivien How, Maisarah Nasution Waras, Jamilatul Wahidah Jamal Rodzi, Nurul Afina Ahmad Zamani, Hafizah Rukman

“…Seventeen families (9 rural, 8 urban) participated in a 16-day cross-over intervention, consisting of a baseline conventional diet phase (4 days), an organic diet phase (7 days), and a post-intervention conventional diet phase (5 days). …”
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Menopausal status, transition, and age at menopause with accelerated biological aging across multiple organ systems: findings from two cohort studies by Yi Xiang, Qiong Meng, Zitong Huang, Ning Zhang, Yuan Zhang, Xianbin Ding, Jianhong Yu, Baimakangzhuo, Leilei Liu, Xiong Xiao, Xing Zhao

“…Results Compared with pre-menopausal women, those who were peri- or post-menopausal or had undergone hysterectomy or oophorectomy exhibited greater acceleration in comprehensive, liver, metabolic, and kidney BA. …”
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Dynamics of G6PD activity in patients receiving weekly primaquine for therapy of Plasmodium vivax malaria. by Walter R J Taylor, Saorin Kim, Sim Kheng, Sinoun Muth, Pety Tor, Eva Christophel, Mavuto Mukaka, Alexandra Kerleguer, Lucio Luzzatto, J Kevin Baird, Didier Menard

“…<h4>Background</h4>Acute Plasmodium vivax malaria is associated with haemolysis, bone marrow suppression, reticulocytopenia, and post-treatment reticulocytosis leading to haemoglobin recovery. …”
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Survey of postoperative practices for lumbar spinal stenosis surgery among canadian spinal surgeons and rehabilitation professionals by Lu Hsi Chen, BHSc, MD(c), Nora Bakaa, DC, PhD, Raja Rampersaud, MD, FRCSC, Marcia Correale, PT, Lisa Carlesso, PT, PhD, Luciana Macedo, PT, PhD

“…Many of the spine surgeons in this study do not (35%) or occasionally refer (27%) their post-LSS surgery patients to outpatient postoperative rehabilitation and do not believe such programs are necessary for all patients (65.4%). …”
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INHIBITION OF THE PROSTAGLANDIN-DEGRADING ENZYME 15-PGDH AMELIORATES MASH-ASSOCIATED APOPTOSIS AND FIBROSIS IN MICE by Utibe-Abasi S. Udoh, Mathew Steven Schade, Jacqueline A. Sanabria, Pradeep Kumar Rajan, Rodrigo Aguilar, Micheal Andryka, Alexei Gorka, Sandrine V. Pierre, Juan Sanabria

“…Statistical analyses between groups (NMC, HFD, and SW033291) were determined by ANOVA, <i>t</i>-test/Tukey’s post hoc test using GraphPad Prism. Metabolomics data were analyzed using R-lab. …”
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Role of laparoscopic surgery in blunt abdominal trauma; retrospective analysis in a tertiary trauma center by Rifan Alyami, Ahad E. Alotaibi, Leen Almohayya, Ajyad Al Jawad, Raghad Almukhayzim, Abeer Alhoumedan, Rakan S. Aldusari

“…Following surgery, 78.4% of the patients underwent therapeutic procedures after laparotomy, while 37.8% received therapeutic interventions post-laparoscopy. Conclusion While laparoscopic techniques have been used for decades in abdominal surgeries, a consensus on their effectiveness and accuracy in diagnosing blunt abdominal injuries in trauma settings is still lacking. …”
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Real-Life Experiences of Self-Capacity Management in Patients with Chronic Heart Failure: A Qualitative Study by Wang A, Zhang N, Li M, Mao Q, Ma A, Wang G, Li M, Li Q

“…Tailored educational programs that cater to individual patient needs are essential for enhancing accessibility and ensuring continuity of care. Regular post-education assessments, alongside continuous supervision and guidance, are crucial to improve patient understanding, promote behavioral changes, validate the effectiveness of educational interventions, and support the long-term adoption of self-management practices.Keywords: heart failure, self-capacity management, patient experience, qualitative research, educational interventions…”
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Perbandingan Luaran Penggunaan Protokol Enhanced Recovery After Surgery (ERAS) dengan Perawatan Perioperatif Konvensional pada Pembedahan Umum di RSUP H. Adam Malik Medan by Moch. Iqbal Saputra, Qadri Fauzi Tanjung, Tasrif Hamdi

“…Luaran yang dinilai dalam penelitian ini adalah skala nyeri pascaoperasi, kejadian post operative nausea and vomiting (PONV), waktu mobilisasi, waktu flatus, dan lama rawat. …”
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Fine-tuning immunity: ubiquitin-dependent regulation of interleukin-17A expression by Th17 cells by Desh Raj, Desh Raj, Desh Raj, Amit K. Verma, Amit K. Verma, Amit K. Verma, Risha Mathur, Risha Mathur, Risha Mathur, Jenna Woody, Jenna Woody, Jenna Woody, Mahesh Kathania, Mahesh Kathania, Mahesh Kathania, K. Venuprasad, K. Venuprasad, K. Venuprasad

“…Recent advances have highlighted the significance of post-translational modifications, particularly ubiquitination, in regulating IL-17A expression and IL-17A receptor signaling pathways. …”
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Frequency of safety signals from scientific reports, manufactures, registers, and other sources for a random selection of hip and knee prostheses by Yijun Ren, Lotje A Hoogervorst, Enrico G Caiani, Perla J Marang-van de Mheen, James A Smith, Alan G Fraser, Rob G H H Nelissen, Anne Lübbeke

“…Annual registry reports from 5 national registries were examined to check whether any of the selected implants had outlier performance. The CORE-MD post-market surveillance (PMS) tool was used to collect all related safety notices from 13 competent authority/regulatory agency websites. …”
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Patients’ Internet Use for Health-Related Purposes: A Cross-Sectional Study by Valentin NĂDĂŞAN, Teodor-Marian BACIU, Alexandra-Maria NEGUŢESCU, Răzvan MOLDOVAN, Roberto CHICOŞ, Agnos-Milian HERŢELIU, Andrea-Ildikó GÁSPÁRIK

“…Approximately half of the respondents (51.2%) had a high school education or less, while 48.7% had post-secondary or university education. Over 65% of respondents searched for health information online frequently or sometimes, while 34.4% did so rarely or never. …”
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Perception of health and illness and quality of life after total thyroidectomy for differentiated thyroid carcinoma: the PERSAM study by Elena Groff, Beatrice Soccal, Fabiola Carrossa, Federica Vianello, Sara Talomo, Alessandra Feltrin, Giovanni Scarzello, Honoria Ocagli, Dario Gregori, Matteo Martinato

“…The primary aim of this study is to assess the quality of life and perception of illness among patients admitted for radiometabolic therapy, post total thyroidectomy for differentiated thyroid carcinoma. …”
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Stem Cells Within Three-Dimensional-Printed Scaffolds Facilitate Airway Mucosa and Bone Regeneration and Reconstruction of Maxillary Defects in Rabbits by Mi Hyun Lim, Jung Ho Jeon, Sun Hwa Park, Byeong Gon Yun, Seok-Won Kim, Dong-Woo Cho, Jeong Hak Lee, Do Hyun Kim, Sung Won Kim

“…<i>Results</i>: In vitro, hNTSCs differentiated into both mucosal epithelial and osteogenic cells. hNTSC differentiation into respiratory epithelial cells was confirmed by Alcian Blue staining, cilia in SEM, and increased expression levels of FOXJ1 and E-cadherin through quantitative RT-PCR. hNTSC differentiation into bone was confirmed by Alizarin Red staining, increased mRNA expression levels of BMP2 (6.1-fold) and RUNX2 (2.3-fold) in the hNTSC group compared to the control. Four weeks post-transplantation, the rabbit maxilla was harvested, and H&E, SEM, and immunohistofluorescence staining were performed. …”
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Creating tools for addressing child trauma in Canada: Caregiver online PsychoEducation (COPE) by Nicole Racine, Cailey Hartwick, Anh Ly, Greta E. Jang, Raela Thiemann, Leslie Obol, Jessica Switzer, Ana Figueras, Gina Dimitropoulos, Sheri Madigan

“…In the absence of psychological interventions and support, children exposed to trauma are at risk of post-traumatic stress disorder and other mental health difficulties. …”
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