Enhancing head and neck cancer detection accuracy in digitized whole-slide histology with the HNSC-classifier: a deep learning approach by Haiyang Yu, Haiyang Yu, Wang Yu, Wang Yu, Yuan Enwu, Yuan Enwu, Yuan Enwu, Jun Ma, Jun Ma, Xin Zhao, Xin Zhao, Linlin Zhang, Linlin Zhang, Linlin Zhang, Fang Yang, Fang Yang, Fang Yang

“…Head and neck squamous cell carcinoma (HNSCC) represents the sixth most common cancer worldwide, with pathologists routinely analyzing histological slides to diagnose cancer by evaluating cellular heterogeneity, a process that remains time-consuming and labor-intensive. …”
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The impact of diarrhoea in infants on the quality of life of low-income households by Montagu Murray, Marije Versteeg, Jannie Hugo

“…Diarrhoea was the cause of tension and conflict in a number of households, not only because of inflated financial costs related to efforts to cope with the illness, but also because of differing views among household members regarding the most suitable treatment Western or traditional medicine. …”
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Exploring Microbial Diversity in Forest Litter-Based Fermented Bioproducts and Their Effects on Tomato (<i>Solanum lycopersicum</i> L.) Growth in Senegal by Alexandre Mahougnon Aurel Zoumman, Paula Fernandes, Mariama Gueye, Clémence Chaintreuil, Laurent Cournac, Aboubacry Kane, Komi Assigbetse

“…Within these groups, the most prevalent classes were <i>Bacilli</i> (14.41–89.82%), <i>α-proteobacteria</i> (2.83–72.09%), and <i>Clostridia</i> (0.024–13.34%). …”
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Evidence of the consequences of the prolonged fire season on air quality and public health from 2024 São Paulo (Brazil) data by Gregori de A. Moreira, Samara Carbone, Juan Luis Guerrero-Rascado, Izabel da S. Andrade, Alexandre Cacheffo, Andrés M. Vélez-Pereira, Ezequiel Zamora-Ledezma, Dirk Thielen, Antonio A. Gomes, Ediclê de S. F. Duarte, Eduardo Landulfo, Fábio J. da S. Lopes, Henrique M. P. Aveiro, Jonatan J. da Silva, Juan Pallotta, Laura S. Pelicer, Luiz G. E. Souza, Maria F. Tames, Maria J. Costa, Marlon M. C. Puig, Mary Luz Puche Cárdenas, Náiade R. Rosa, Paloma Cariñanos, Thiago P. Diaz

“…This phenomenon, combined with unfavorable conditions for pollutant concentrations, given temperature and precipitation anomalies, resulted in high concentrations of pollutants for several weeks, mainly affecting the number of hospitalizations of the most vulnerable age groups, children (due to respiratory diseases) and older adults (due to cerebrovascular diseases) in the city of São Paulo. …”
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Patients’ acceptance toward elective induction of labor at 39th week of gestation among low-risk pregnancies in a tertiary hospital in Vietnam: the PALI studyAJOG Global Reports at... by Ha Thi Thu Nguyen, PhD, Giang Thi Tra Duong, MD, Thanh Hoang Luong, MD, Dat Tuan Do, PhD, Thuong Thi Huyen Phan, PhD, Toan Khac Nguyen, MD, Anh Duy Nguyen, PhD

“…Results: For 200 pregnant women who participated in the study at 36 weeks, the 3 most common reasons for IOL prior to the due date were maternal indications, fetal indications, and a convenient day for pregnant women, about 88%, 87%, and 80%, respectively. …”
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Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection: a prospective, randomized, controlled, single-center,... by Jian Yang, Chan Liu, Jianxiong Li, Xianqiu Chen, Beibei Wang, Jing Zhang, Haifeng Wang, Deping Zhao, Yiming Zhou, Haomin Cai, Jin-fu Xu, Shuo Liang

“…Abstract Background Surgical resection is considered the most effective therapeutic method for pulmonary aspergilloma (PA), while the necessity of postoperative antifungal therapy remains controversial. …”
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Mapping global leaf inclination angle (LIA) based on field measurement data by S. Li, S. Li, S. Li, H. Fang, H. Fang

“…This study shows that the common spherical and constant LIA assumptions may underestimate the interception of most vegetation types. The MLA and <span class="inline-formula"><i>G</i>(0)</span> products derived in this study could enhance our knowledge of global LIA and should greatly facilitate remote sensing retrieval and land surface modeling studies.…”
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Stage at diagnosis and tumor characteristics among young women and men with breast cancer, in Ethiopia and Sweden, a descriptive cross-sectional study by Tove Ekdahl Hjelm, Tewodros Yalew Gebremariam, Mahlet Fekadu Weldearegay, Moti Sori, Marcus Bauer, Bethlehem Ayele Getachew, Mathewos Assefa, Endale Anberber, Hidaya Yahya Mohammed, Eva Johanna Kantelhardt, Sara Margolin, Annika Lindblom, Senait Ashenafi, Jenny Löfgren

“…The ER- and/or PgR-positive/HER2-negative subtype was the most common in both groups: (68.0% in Ethiopian patients and 47.5% in Swedish patients). …”
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Model for predicting risk of developing drug-induced liver injury during remdesivir therapy: observational prospective open case-control study by Yu. V. Shevchuk, A. V. Kryukov, I. I. Temirbulatov, I. V. Sychev, K. B. Mirzaev, N. P. Denisenko, Sh. P. Abdullaev, S. N. Tuchkova, V. I. Vechorko, O. V. Averkov, D. A. Sychev

“…According to a number of studies, the incidence of adverse reactions during remdesivir therapy reaches 66%, with the most common is an increase in liver function tests.The aim of the work was to study the influence of clinical, demographic and pharmacogenetic factors on the development of drug-induced liver damage during remdesivir therapy in COVID-19 patients.Materials and methods. …”
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Functional Component Production Capabilities in Milk Fermentation of Some Featured Lactic Acid Bacteria Species for Use in Different Food Processes by Tuğba Kök Taş, Fatma Ecemnur Duran, Nilgün Özdemir, Ebru Çubuk Demiralay

“…A total of 62 volatile compounds were identified, with the highest levels of aromatic components found in products containing <i>B. bifidum</i>. The most preferred product, based on panel evaluations, was the fermented dairy product produced with <i>L. acidophilus</i>. …”
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RAD51B in Familial Breast Cancer. by Liisa M Pelttari, Sofia Khan, Mikko Vuorela, Johanna I Kiiski, Sara Vilske, Viivi Nevanlinna, Salla Ranta, Johanna Schleutker, Robert Winqvist, Anne Kallioniemi, Thilo Dörk, Natalia V Bogdanova, Jonine Figueroa, Paul D P Pharoah, Marjanka K Schmidt, Alison M Dunning, Montserrat García-Closas, Manjeet K Bolla, Joe Dennis, Kyriaki Michailidou, Qin Wang, John L Hopper, Melissa C Southey, Efraim H Rosenberg, Peter A Fasching, Matthias W Beckmann, Julian Peto, Isabel Dos-Santos-Silva, Elinor J Sawyer, Ian Tomlinson, Barbara Burwinkel, Harald Surowy, Pascal Guénel, Thérèse Truong, Stig E Bojesen, Børge G Nordestgaard, Javier Benitez, Anna González-Neira, Susan L Neuhausen, Hoda Anton-Culver, Hermann Brenner, Volker Arndt, Alfons Meindl, Rita K Schmutzler, Hiltrud Brauch, Thomas Brüning, Annika Lindblom, Sara Margolin, Arto Mannermaa, Jaana M Hartikainen, Georgia Chenevix-Trench, kConFab/AOCS Investigators, Laurien Van Dyck, Hilde Janssen, Jenny Chang-Claude, Anja Rudolph, Paolo Radice, Paolo Peterlongo, Emily Hallberg, Janet E Olson, Graham G Giles, Roger L Milne, Christopher A Haiman, Fredrick Schumacher, Jacques Simard, Martine Dumont, Vessela Kristensen, Anne-Lise Borresen-Dale, Wei Zheng, Alicia Beeghly-Fadiel, Mervi Grip, Irene L Andrulis, Gord Glendon, Peter Devilee, Caroline Seynaeve, Maartje J Hooning, Margriet Collée, Angela Cox, Simon S Cross, Mitul Shah, Robert N Luben, Ute Hamann, Diana Torres, Anna Jakubowska, Jan Lubinski, Fergus J Couch, Drakoulis Yannoukakos, Nick Orr, Anthony Swerdlow, Hatef Darabi, Jingmei Li, Kamila Czene, Per Hall, Douglas F Easton, Johanna Mattson, Carl Blomqvist, Kristiina Aittomäki, Heli Nevanlinna

“…The association with previously identified risk variants rs999737, rs2588809, and rs1314913 was replicated among all breast cancer cases and also among familial cases in the BCAC dataset. The most significant association was observed for the haplotype carrying the risk-alleles of all the three SNPs both among all cases (odds ratio (OR): 1.15, 95% confidence interval (CI): 1.11-1.19, P = 8.88 x 10-16) and among familial cases (OR: 1.24, 95% CI: 1.16-1.32, P = 6.19 x 10-11), compared to the haplotype with the respective protective alleles. …”
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Evaluating the roles of microRNAs associated with nonalcoholic fatty liver disease in hepatocellular carcinoma tumorigenesis: a systematic review and network analysis by Qinghua Peng, Qinghua Peng, Xiaoning Zhu, Xiaoning Zhu, Xiaoning Zhu, Yuanyuan Jiang, Yuanyuan Jiang, Mengyun Peng, Mengyun Peng, Ding Zheng, Ding Zheng, Xiaodong Wang, Xiaodong Wang, Yoke Kqueen Cheah, Yoke Kqueen Cheah, Jing Wang, Jing Wang

“…Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide, with high morbidity and mortality. …”
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The association between sociodemographic determinants and nomophobia among physiotherapists in the Kingdom of Saudi Arabia: a cross-sectional study by Abdulelah M. Aldhahir, Jaber S. Alqahtani, Abdullah A. Alqarni, Omar A. Alqarni, Hassan Alwafi, Abdallah Y. Naser, Mohammed M. Alyami, Ahmed H. Alasimi, Husam I. Alahmadi, Mansour S. Majrshi, Shaima A. Alothman, Mohammed A. Zalah, Ghazi I. Hakami, Abdulaziz A. Rajhi, Ramya R. Sanjeevi, Karthick Balasubramanian, Khadijah N. Alshehri, Mohammed M. Alshehri

“…Nomophobia is highly prevalent among physiotherapists, with most reporting moderate levels. Interventions to promote balanced mobile phone use and digital well-being are recommended to improve mental health, job satisfaction, and productivity, fostering a healthier work environment.…”
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National and subnational burden of brain and central nervous system cancers in China and global from 1990 to 2021: results from the global burden of disease study 2021 by Shifan Tu, Xiaolu Huang, Xiaoxuan Fan, Yi Zhang, Lan Huang, Kai Li, Xinyue Wang, Yunpeng Gao, Xiaoping Zhao, Zhaoqun Feng

“…Through systematic analysis of temporal trends in age- and sex-specific burdens of primary CNS cancers in China—including incidence, prevalence, mortality, and disability-adjusted life years (DALYs)—this study establishes a novel comparative framework aligned with global disease burden metrics. Leveraging the most recent data from the GBD 2021, we elucidate disparities in disease burden and evolving trends between China and global regions. …”
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Treatment Patterns and Triple Therapy Utilization in Chinese Patients with Chronic Obstructive Pulmonary Disease: An Analysis of Real-World Data from the Yinzhou Database by Chen Y, Li X, Hou D, Li W, Liu Z, Zhang M, Cheang I, Shen P, Lin H, Zhan S, Sun F, Song Y

“…Triple therapy was also widely used, with most patients transitioning from other treatment modalities.Keywords: COPD, ICS, LABA, LAMA…”
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Clinical Practice Guidelines of Russian Gastroenterological Association, Scientific Society for the Clinical Study of Human Microbiome, Russian Society for the Prevention of Non-Co... by V. T. Ivashkin, T. L. Lapina, I. V. Maev, O. M. Drapkina, R. S. Kozlov, A. A. Sheptulin, A. S. Trukhmanov, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, D. S. Bordin, N. N. Dekhnich, I. L. Klyaritskaya, N. V. Korochanskaya, M. F. Osipenko, E. A. Poluektova, A. S. Sarsenbaeva, V. I. Simanenkov, A. V. Tkachev, A. I. Ulyanin, I. B. Khlynov, V. V. Tsukanov

“…The serological method cannot be used after anti-Helicobacter therapy.In Russia H. pylori strains' resistance to clarithromycin does not exceed 15 % in most regional studies. The first line therapy for Н. pylori infection eradication is the standard triple therapy including a proton pump inhibitor (PPI), clarithromycin and amoxicillin, enhanced with bismuthate tripotassium dicitrate. …”
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Comparison of tracer application methods for sentinel lymph node detection in open surgery patients with endometrial cancer: a retrospective cohort study by Borek Sehnal, Petr Waldauf, Radoslav Matej, Martin Hruda, Helena Robova, Jana Drozenova, Tomas Pichlik, Jan Zapletal, Lukas Rob, Michael J. Halaska

“…Overall, older age emerged as the most critical risk factor for SLN detection failure, while other assessed factors did not show a statistically significant impact on overall detection success. …”
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A dual fluorescence channel RAA-based CRISPR-Cas12a/Cas13a system for highly sensitive detection of Gyrovirus galga1 and Gyrovirus homsa1 by Dan Yu, Zhixun Xie, Yanfang Zhang, Zhiqin Xie, Qing Fan, Sisi Luo, Liji Xie, Meng Li, Tingting Zeng, Minxiu Zhang, Xiaofeng Li, You Wei, Aiqiong Wu, Lijun Wan

“…Gyrovirus galga1 (GyG1) and Gyrovirus homsa1 (GyH1) are the second and third most common gyroviruses identified, respectively, after chicken anaemia virus. …”
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Evaluation of the effect of Holstein bulls breeding value on cows’ milk productivity of Ukrainian Black-and-White dairy breed by V. V. Mykytiuk, P. V. Bodnar, A. O. Boiko, L. I. Muzyka, V. Ye. Bodnaruk, A. Y. Zhmur

“…Thus, according to quantitative characteristics, the difference was significant (P ≤ 0.05–0.001) only between groups I & III – for the first lactation, as well as between groups I & III and II & III – both for the second and higher lactations. The most significant effect of the factor “father's BV for BI” on the milk productivity of daughters was set up in the second lactation (4.81–10.04 %; P ≤ 0.05–0.001 for various characteristics). …”
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Preventive Gastroprotective Effect of a Functional Food Based on Quinoa (<i>Chenopodium quinoa</i> Willd.) and Quercetin in a Murine Model of Ibuprofen-Induced Gastric Damage by Maribel Valenzuela-González, José Luis Cárdenas-López, Armando Burgos-Hernández, Norma Julieta Salazar-López, Manuel Viuda-Martos, Mónica A. Villegas-Ochoa, Gustavo Martínez-Coronilla, J. Abraham Domínguez-Avila, Shela Gorinstein, Gustavo A. González-Aguilar, Rosario Maribel Robles-Sánchez

“…Co-medication with omeprazole (OMP) is the most commonly used option to prevent these lesions, although this carries risks of its own; thus, alternatives are being explored, such as dietary antioxidant therapies. …”
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