Atypical symptoms and delayed diagnosis are more common in elderly patients with benign paroxysmal positional vertigo: a single-center study by Hongyan Li, Hongyan Li, Yanping Tong, Yan Wang, Yan Wang, Meimei Chen, Meimei Chen, Yu Cui, Yu Cui, Xiaolin Wu, Xiaolin Wu, Yi Ju, Yi Ju

“…The posterior semicircular canal was the most commonly affected site (62.3%) in elderly patients, and the incidence of horizontal semicircular canal canalolithiasis was higher in the elderly group compared to the young-to-middle-aged group (16.2% vs. 13.6%, p < 0.001). …”
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Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review by Chengna Wang, Chengna Wang, Wenxin Ma, Lingling Qin, Lingling Qin, Lili Wu, Tonghua Liu

“…While XYSJW outperforms OS preparations in lowering TgAb levels, it may not surpass OS in restoring thyroid hormone levels. Most studies reviewed are of low quality. XYS preparations appear to modulate cytokines by targeting immune markers and reducing inflammation, but their safety profile remains unclear, requiring further robust evidence.Systematic Review Registrationclinicaltrials.gov, identifier CRD42023472233.…”
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Seasonal Changes in Performance Metrics, Hormonal, Hematological, and Biochemical Markers Among Semi-Professional Soccer Players: Implications for Training and Recovery by Eleftherios Mylonis, Dimitrios I. Bourdas, Natalia Kompodieta, Athanasios Tegousis, Panteleimon Bakirtzoglou, Athanasios Souglis, Evangelos Bekris

“…Stability in lower limb strength, flexibility, triglycerides, C-reactive protein, ferritin, liver enzymes, and most hematological parameters suggest resilience to seasonal demands. …”
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Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol by Roberta de Oliveira Cacho, Carla Heloisa Cabral Moro, Rodrigo Bazan, Suzete Nascimento Farias da Guarda, Elen Beatriz Pinto, Suellen Mary Marinho dos Santos Andrade, Lenise Valler, Kelson James Almeida, Tatiana Souza Ribeiro, Renata Viana Brígido de Moura Jucá, Cesar Minelli, Maria Elisa Pimentel Piemonte, Eric Homero Albuquerque Paschoal, Marco Túlio Araújo Pedatella, Octávio Marques Pontes-Neto, Ana Paula Fontana, Aline de Souza Pagnussat, Adriana Bastos Conforto

“…Background Most of the Brazilian population relies on public healthcare and stroke is a major cause of disability in this country of continental dimensions. …”
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The Impact of Stellar Rotations and Binaries on the Shape of Upper Main Sequence near Turnoff in Open Cluster NGC 6067 by Jayanand Maurya, Yu Zhang, Sebastian Kamann, Hubiao Niu, Yves Frémat, Kaixiang Lang, Y. C. Joshi, M. R. Samal, Peter De Cat, Ali Esamdin

“…The gravity-darkening effect might be a reason for this correlation. We find that most of the close binaries present in the eMSTO population would be slow-rotating due to the tidal-locking phenomenon. …”
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Aspirin Resistance as a Result of Impaired Interaction of Platelets and Neutrophils in Patients with Coronary Heart Disease by M. D. Goncharov, A. A. Savchenko, Yu. I. Grinshtein, I. I. Gvozdev, A. A. Kosinova, T. S. Mongush

“…On the 8–10th day after CABG, most indicators of spontaneous and zymosan-induced CL neutrophils in rASA patients were also increased compared to control values. …”
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Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target by L. Llaó-Cid, JKL Wong, I. Fernandez Botana, Y. Paul, M. Wierz, L-M Pilger, A. Floerchinger, CL Tan, S. Gonder, G. Pagano, M. Chazotte, K. Bestak, C. Schifflers, M. Iskar, T. Roider, F. Czernilofsky, P-M Bruch, JP Mallm, A. Cosma, DE Campton, E. Gerhard-Hartmann, A. Rosenwald, D. Colomer, E. Campo, D. Schapiro, EW Green, S. Dietrich, P. Lichter, E. Moussay, J. Paggetti, M. Zapatka, M. Seiffert

“…T cells in CLL lymph nodes show the most distinct profiles, with accumulation of regulatory T cells and CD8+ T cells in various exhaustion states, including precursor (TPEX) and terminally exhausted (TEX) cells. …”
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Exploring the potential transdiagnostic treatment effects of Chinese herbal medicine and acupuncture on insomnia disorder comorbid with chronic pain: A scoping review by Yan Ling Kwok, Ran Wang, Hiu To Tang, Siyu Chen, Albert Yeung, Zhaoxiang Bian, Danny J. Yu

“…Combined CHM (Da Huoluo capsules) and acupuncture showed medium effects (d = 0.72 for insomnia; d = 0.57 for pain) versus multi-medications/traction. Most studies (83.33 %) had high risk of bias. Conclusion: CHM and acupuncture show promise for ICCP management, but high risk of bias warrants cautious interpretation and further high-quality RCTs.…”
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Analysis of homologous recombination deficiency in prostate cancer by A. G. Iyevleva, S. N. Aleksakhina, A. P. Sokolenko, E. A. Otradnova, A. S. Nikitina, K. A. Kashko, M. V. Syomina, N. S. Morozova, A. D. Shestakova, E. Sh. Kuligina, E. N. Imyanitov

“…In contrast to BRCA2-associated PCs, most tumors with mutations in the CHEK2, NBN, BLM, FANCM, BRCA1 genes are not characterized by homologous recombination deficiency. in the case of ATM gene lesions, approximately half of pcs have a high HRD score. …”
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Platelet-derived exosomal LINC00183 facilitate colorectal cancer malignant progression driven by histone lactylation through stabilizing ENO1 by Guoqing Su, Jinghang Qian, Yi Wang, Yu Zhu, Yanyan Chen, Jingru Shen, Jiayuan Jiang, Yuepeng Cao, Nannan Wang, Xing Huang, Chengshuai Si, Xu Zhang, Peng Shao, Yongxia Ye, Yang Wang, Jun Bao, Liu Yang

“…Using RNA sequencing, we identified LINC00183 as the most upregulated lncRNA in platelet-derived exosomes (PLT-Exos) from CRC patients, compared to healthy individuals. …”
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Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer by Angela Santonja, Wendy N Cooper, Matthew D Eldridge, Paul A W Edwards, James A Morris, Abigail R Edwards, Hui Zhao, Katrin Heider, Dominique‐Laurent Couturier, Aadhitthya Vijayaraghavan, Paulius Mennea, Emma‐Jane Ditter, Christopher G Smith, Chris Boursnell, Raquel Manzano García, Oscar M Rueda, Emma Beddowes, Heather Biggs, Stephen‐John Sammut, Nitzan Rosenfeld, Carlos Caldas, Jean E Abraham, Davina Gale

“…Hybrid capture sequencing targeting between 1,347 and 7,491 tumor‐identified mutations at high depth was the most sensitive assay, detecting ctDNA down to an AF of 0.00024% (2.4 parts per million, ppm). …”
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Qualidade de vida de indivíduos portadores de dispositivo cardíaco eletrônico implantável [Quality of life of individuals with implantable electronic cardiac device] [Calidad de v... by Líscia Divana Carvalho Silva, Édipo Luan de Carvalho Caminha, Nerilce Soares Ferreira

“…SF-36 and AQUAREL were used. Results: the most frequent comorbidity was systemic arterial hypertension – 39 (78%), baseline heart disease bradycardia – 18 (36%) and complaints of palpitation and pre-syncope. …”
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State of the Journal: 2023 by Sheba Nakacubo Gitta

“…Outbreaks, epidemics and pandemics continue to occur; most important among them COVID-19 and several disease outbreaks which included Mpox (formerly Monkeypox), Ebola Virus Disease (EVD) and cholera [1]. …”
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HC-Pro inhibits HEN1 methyltransferase activity, leading to autophagic degradation of AGO1 by Zhao-Jun Pan, Wei-Lun Wei, Phuong-Anh Tran, Ru-Ying Fang, Thanh Ha Pham, John L. Bowman, Chao-Tzu Chung, Bing-Nan Shen, Ju-Ting Yang, Han-Han Chang, Wann-Neng Jane, Chiung-Hsiang Cheng, Chia-Chi Wang, Hsin-Yi Wu, Syuan-Fei Hong, Qian-Wen Shang, Sin-Fen Hu, Pin-Chun Lin, Fu-Hui Wu, Choun-Sea Lin, Yu-Ling Hung, Tang-Long Shen, Shih-Shun Lin

“…P1/HC-Pro from turnip mosaic virus (P1/HC-ProTu) exhibited the most potent inhibition of HEN1, followed by P1/HC-Pro from zucchini yellow mosaic virus (P1/HC-ProZy), while P1/HC-Pro from tobacco etch virus (P1/HC-ProTe) showed the weakest inhibitory effect. …”
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Clinical Trial to Evaluate the Effect of Grape Seed Extract-Loaded Hyalurosomes on Skin Wellness by Rita Abi Rached, Maya Habre, Yara Salem, Joe Khodeir, Mohamad Allaw, Ines Castangia, Hiba N. Rajha, Luciana Habre, Joelle Feghali, Joe A. Touma, Maria Letizia Manca, Nicolas Louka, Maria Manconi, Richard G. Maroun

“…The aim of this study was to extract phytochemicals from the Lebanese grape variety “Obeidi” and incorporate them into liposomes and hyalurosomes in order to select the most effective formulation for improving skin properties and protecting against oxidative damage. …”
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Comparative effectiveness of non-pharmacological interventions on anxiety, depression, and quality of life in patients with epilepsy: a systematic review and network meta-analysis by Haoran Luo, Xianming Ding, Junyu Zhang, Ningkun Xiao, Ningkun Xiao

“…SUCRA rankings suggested that Enhanced education therapy (EET), Psychotherapy (PT), and Enhanced care (EC) were the most effective interventions for improving anxiety, depression, and Quality of Life (QoL), respectively. …”
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“Our work is recognized and we are prepared:” A qualitative evaluation of a peer-led research best practices training for community health workers and promotoras by Alexandra E. Harper, Analay Perez, M. Miaisha Mitchell, Daphne Watkins, Gina M. Jay, Vanessa I. Trujillo, Kristen Weeks-Norton, Shannen McIntosh, Brenda Eakin, Elias Samuels, Gretchen Piatt, Catherine Striley, Linda Cottler, Sergio Aguilar-Gaxiola, Susan L. Murphy

“…The mean age was 43.7 ± 14.5 years, most were female (59%), and 47% identified as Hispanic, Latino, or Spanish. …”
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Gender peculiarities of paranoid schizophrenia in the modern context by Ya. Yu. Marunkevych

“…It was established that the most common symptoms of paranoid schizophrenia were expressed and significant changes in the general behavioral quality (100.0 %), negative symptoms (96.1%) and persistent delusional symptomatology (93.1 %), while chronic paranoid symptoms (66.7 %) and delusion of mastery, influence or inactivity, and delusional perception (61.8 %), as well as verbal hallucinations (58.8 %) were less common. …”
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Mapping QTLs for Pyricularia leaf spot, nematode resistance, and yield related traits in pearl millet [Cenchrus americanus (L.) Morrone] by Sairam Vutla, Joseph E. Knoll, Anvesh Sankuratri, Risha G. Nayak, Limei Liu, Limei Liu, Peng W. Chee, Raghupathy Karthikeyan, Bashasab Fakrudin, Mahendar Thudi, Patricia Timper, Karen Harris-Shultz, Jason G. Wallace, Jason G. Wallace, Hari Singh, Bharat Singh, Somashekhar M. Punnuri

“…Morrone, formerly Pennisetum glaucum (L.) R. Br.] is the sixth most important cereal globally and is used for forage and feed in the U.S. …”
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Biomolecular Predictors of Recurrence Patterns and Survival in IDH-Wild-Type Glioblastoma: A Retrospective Analysis of Patients Treated with Radiotherapy and Temozolomide by Paolo Tini, Flavio Donnini, Francesco Marampon, Marta Vannini, Tommaso Carfagno, Pierpaolo Pastina, Giovanni Rubino, Salvatore Chibbaro, Alfonso Cerase, Giulio Bagnacci, Armando Perrella, Maria Antonietta Mazzei, Alessandra Pascucci, Vincenzo D’Alonzo, Anna Maria Di Giacomo, Giuseppe Minniti

“…Background and Aim: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with poor prognosis despite maximal surgical resection, radiotherapy (RT), and temozolomide (TMZ) per the Stupp protocol. …”
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