Role of Preoperative Breast MRI in Predicting Tumor-Infiltrating Lymphocytes in Breast Cancer: Is There an Association with Tumor Biological Subtypes? by Silvia Gigli, Emanuele David, Giacomo Bonito, Luisa Favale, Silvia di Sero, Antonio Vinci, Lucia Manganaro, Paolo Ricci

“…The ADC values and the enhancing characteristics were the most important factors in predicting TIL levels, according to logistic regression analysis, and when combined, they demonstrated the strongest ability to distinguish between the two groups (AUC = 0.744). …”
Get full text

Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway by Ariel Rechtman, Ariel Rechtman, Omri Zveik, Omri Zveik, Lyne Shweiki, Lyne Shweiki, Garrick Hoichman, Garrick Hoichman, Garrick Hoichman, Tal Friedman-Korn, Tal Friedman-Korn, Livnat Brill, Livnat Brill, Adi Vaknin-Dembinsky, Adi Vaknin-Dembinsky

“…In vitro treatment with immunosuppressives led to a significant increase in sCD83 levels with the most pronounced effect observed following treatment with mycophenolate mofetil.DiscussionOur study consistently found lower sCD83 levels in NMOSD and relapsing MOGAD patients. sCD83 levels increased following IVIG and immunosuppressive therapy. …”
Get full text

FutureMS cohort profile: a Scottish multicentre inception cohort study of relapsing-remitting multiple sclerosis by David Hunt, Siddharthan Chandran, Peter Connick, Peter Foley, Patrick K A Kearns, Sergio E Baranzini, Adam D Waldman, Sarah J Martin, Elizabeth Freyer, F J Carod-Artal, Lee Murphy, Amy Stenson, Jessie Chang, Rozanna Meijboom, Elizabeth N York, Yingdi Chen, Christine Weaver, Katarzyna Hafezi, Stacey Thomson, Adil Harroud, Margaret McLeod, Jonathon O'Riordan, Niall J J MacDougall

“…Purpose Multiple sclerosis (MS) is an immune-mediated, neuroinflammatory disease of the central nervous system and in industrialised countries is the most common cause of progressive neurological disability in working age persons. …”
Get full text

Predictive Factors of Pelvic Organ Prolapse and the Quality of Life Among Jordanian Women: A Case-Control Study by Qatawneh A, Qudah S, Alkouz D, Kadah A, Abu Salma B, Al-Alawneh W, Alhabosh S, Salahaldeen M, Banihamad BA, Aldmour BA, Alkouz N, Alqatawneh A, Muhaidat N, Thekrallah F, Abufaraj M

“…Cystocele and rectocele were the most identified types of prolapse. Nearly 65% of women reported that they had an episiotomy during their deliveries, and 14% reported that there was a family history of prolapse. …”
Get full text

Correlation between mixed exposure to several heavy metals during early pregnancy and fetal low birth weight: Possible mediating effect of mitochondrial DNA copy number by Zhanyue Zheng, Tianao Sun, Minli Yang, Qitao Tan, Minglian Pan, Yingjie Zhou, Yongjie Ma, Yan Sun

“…Random forest analysis identified five metals—As, Se, Tl, Mn and Cd —as most strongly associated with the risk of preterm birth in LBW cases. …”
Get full text

Liver Cirrhosis as the Outcome of Non-Alcoholic Fatty Liver Disease Associated with PNPLA3 Gene RS738409 Polymorphism by I. G. Nikitin, A. S. Tikhomirova, T. A. Zhinzhilo, E. V. Vinnitskaya, Y. G. Sandler, V. A. Kislyakov, I. G. Fedorov

“…Relevance: Non-alcoholic fatty liver disease is the most common liver disease worldwide. Although the disease usually has a favorable, asymptomatic course, in some cases it can occur in the form of non-alcoholic steatohepatitis, and some patients may develop cirrhosis of the liver and hepatocellular carcinoma. …”
Get full text

Peculiarities of clinical and metabolic profile of patients with coronary artery disease associated with type 2 diabetes mellitus (retrospective analysis) by N. S. Mykhailovska, T. O. Kulynych, O. V. Shershnova, Ye. I. Bazun, I. S. Bocharnykova, V. E. Padafa, A. O. Kolesnykova, Yu. V. Hura

“…Coronary artery disease (CAD) is one of the most common reasons of disability and mortality. …”
Get full text

Dual IRE1 RNase functions dictate glioblastoma development by Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Eric Chevet

“…This concept is valid in glioblastoma multiform (GBM), the most lethal primary brain cancer with no effective treatment. …”
Get full text

Nonlinear Dynamics Induced by Optical Injection in Optical Frequency Combs Generated by Gain-Switching of Laser Diodes by Ana Quirce, Alejandro Rosado, Jaime Diez, Angel Valle, Antonio Perez-Serrano, Jose-Manuel G. Tijero, Luis Pesquera, Ignacio Esquivias

“…Different regions of locked combs with a tongue shape around detuning values given by multiples of <inline-formula><tex-math notation="LaTeX">$f_R$</tex-math></inline-formula> appear in the maps. P1 and P2 are the most widespread locked states for large values of the modulation amplitude. …”
Get full text

Feeding incremental amounts of the red seaweed Chondrus crispus: Effects on production performance, methane emissions, nutrient utilization, and ruminal and iodine metabolism in da... by D.C. Reyes, J.P. Sacramento, C.T.C. Quigley, B.S. Twining, A.B. Michaud, D. Emerson, B. Honisch, O. Keleher, M.A. Rahman, N.N. Price, A.F. Brito

“…Diets were fed as TMR, with the control treatment (0% C. crispus) consisting of (DM basis) 60% mixed-mostly grass baleage and 40% ground corn-soybean meal-based concentrate mash, with forage and grain (up to 2.1% each) replaced by 3% and 6% C. crispus in the remaining 2 diets. …”
Get full text

Effectiveness of Radiomics-Based Machine Learning Models in Differentiating Pancreatitis and Pancreatic Ductal Adenocarcinoma: Systematic Review and Meta-Analysis by Lechang Zhang, Dewei Li, Tong Su, Tong Xiao, Shulei Zhao

“…All studies adopted a case-control design, with 5 conducted across multiple centers. Most studies used CT as the primary imaging modality. …”
Get full text

Microbial Multidrug-Resistant Organism (MDRO) Mapping of Intensive Care Unit Infections by Ahmed Yassin, Ragaey Ahmad Eid, Mohammad Farouk Mohammad, Marwa O. Elgendy, Zeinab Mohammed, Mohamed E. A. Abdelrahim, Ahmed M. Abdel Hamied, Reem Binsuwaidan, Asmaa Saleh, Mona Hussein, Eman Hamdy Mohamed

“…MDROs accounted for 42% of infections. The most commonly detected MDRO was <i>Klebsiella</i> spp. (52%). …”
Get full text

Is the Existing Measles Vaccination Schedule in the Russian Federation Effective? by O. V. Tsvirkun, A. G. Gerasimova, N. V. Turaeva, N. T. Tikhonova, A. A. Melnikova, A. A. Vatolina

“…For more u For a more in-depth analysis, the years of the increase in the incidence of 2012, 2014, 2019, 2023 and 2024 were selected, when the patterns of involvement of this analyzed group in the epidemic process of measles were most pronounced. The Pearson coefficient was used to determine the correlation.Results and discussions. …”
Get full text

Optimasi Weight AHP Menggunakan Genetic Algorithm untuk Rekomendasi Platform Media Sosial Sebagai Sarana Promosi Digital by Risqy Siwi Pradini, Mochammad Anshori, M. Syauqi Haris

“…One of the main challenges faced by marketers for digital promotion is how to choose the most appropriate social media platforms to achieve optimal promotional goals. …”
Get full text

Emergence, Spread of Antimicrobial-Resistant Bacteria and Phylogenetic Relationships in Coastal Ecosystems—Gastropod <i>Phorcus lineatus</i> as a Bioindicator by Dércia Santos, Ana Rita Pinto, Rita Barata, Conceição Fernandes, Hugo Guedes, Gonçalo Almeida, Edna Cabecinha, Sandra M. Monteiro, Simone Varandas, Maria José Saavedra

“…Among the isolates, phylogroups A and B2 were the most prevalent, followed by phylogroup B1. The isolates of phylogroup A showed a higher prevalence of antimicrobial resistance. …”
Get full text

Complete Blood Count-Derived Biomarkers’ Association with Risk of PD-1 or PD-1/CTLA-4 Inhibitor-Induced Hypothyroidism in Patients with Solid Tumors by Ketevan Lomidze, Nino Kikodze, Marine Gordeladze, Nino Charkviani, Tinatin Chikovani

“…Background: A novel and highly effective strategy for tumor immunotherapy involves enhancing host immune responses against tumors through the blockade of checkpoint molecules. The most common toxicities associated with checkpoint blockade therapies include autoimmune damage to various organs. …”
Get full text

Dietary Lagenaria siceraria fruit improves growth, gene expression, histology, and immune-antioxidant defense to overcome the Fusarium solani challenge in Litopenaeus vannamei by Moaheda E.H. Eissa, Ehab El-Haroun, Hanan Mohammed Rashwan, Zulhisyam Abdul Kari, Roshmon Thomas Mathew, Dalal Sulaiman Alshaya, Najah M. Albaqami, Layla A. Almutairi, Sultan Mohammed Areshi, Mada M. AL-Qurashi, Yasmin M. Abd El-Aziz, El-Sayed Hemdan Eissa, Afaf N. Abdel Rahman

“…Dietary LS enrichment improved growth and feed efficiency variables as well as fish survival. The most favorable outcomes were in the LS10 diet. The ash content and amylase activity were enhanced by LS supplementation. …”
Get full text

Mapping the landscape of carbon trading & carbon offset research: A global and Indonesian perspective by Arief Heru Kuncoro, Afri Dwijatmiko, Noer’aida, Vetri Nurliyanti, Agus Sugiyono, Widhiatmaka, Andri Subandriya, Nurry Widya Hesty, Cuk Supriyadi Ali Nandar, Irhan Febijanto, La Ode Muhammad Abdul Wahid, Paul Butarbutar

“…These findings underscore the need for further, more in-depth research to identify the most effective carbon trading mechanisms specific to Indonesia’s unique context. …”
Get full text

Real-World Assessment of the Association Between PCSK9i Adherence and LDL Reduction and Variability in a Chinese Clinical Practice by Ye X, Zhang S, Zhong X, Li M, Liu M, Zhuang X, Liao X

“…For every 0.1-unit increase in PDC, the LDL-C standard deviation decreased by 0.042 units, indicating improved lipid stability with higher adherence.Conclusion: The adherence to PCSK9i presented as a skewed distribution, most people only received one injection, which did not reach the ideal adherence goal. …”
Get full text

The Contribution of the Hotel Industry on Youth Empowerment in Mbarara City: A Case Study of Hotel Triangle Mbarara City. by Owomuhangi, Emmanuel

“…It was found out that in a view that most hotels provide sufficient pay for the youth employees, only 13% agreed which proved that it was not the case.…”
Get full text