Effect of infections, DNA methylation and telomere length on frailty trajectories in hospitalized older patients: the INFRAGEN study protocol by Wenxiang Guo, Leonardo Bencivenga, Bruno Micael Zanforlini, Chiara Curreri, Maria Cristina Ferrara, Benedetta Maisano, Luca Tinelli, Laura Andreea Ceparano, Raffaella Merenda, Chiara Cosma, Lucia Manfron, Nicolò Gentili, Silvia Sturani, Monica Cardi, Alice Campion, Benedetta Berardi, Martina Lombardi, Elisabetta D’Aversa, Francesca Salvatori, Veronica Tisato, Joanne Vanessa Vargas, Grazia Daniela Femminella, Donato Gemmati, Giuseppe Sergi, Giuseppe Bellelli, Paolo Mazzola, Caterina Trevisan, Stefano Volpato, the INFRAGEN working group

“…Abstract Background Infectious diseases are among the most common causes of hospitalization in older adults and may lead to a high burden on the individual’s health and healthcare system. …”
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Short-Beam Shear Fatigue Behavior on Unidirectional GLARE: Mean Shear Stress Effect, Scatter, and Anisotropy by Douglas G. Caetano, Hector G. Kotik, Juan E. Perez Ipiña, Enrique M. Castrodeza

“…<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mi mathvariant="bold-italic">R</mi></mrow><mrow><mi mathvariant="bold-italic">τ</mi></mrow></msub></mrow></semantics></math></inline-formula> 0.1 was the most severe condition and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mi mathvariant="bold-italic">R</mi></mrow><mrow><mi mathvariant="bold-italic">τ</mi></mrow></msub></mrow></semantics></math></inline-formula> 0.5 was the least severe. …”
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Molecular analysis of influenza A(H3N2) in a remote tropical island during 2014-2019 to identify the frequency of introduction and local circulation by Sikandar Azam, Takeaki Imamura, Michiko Okamoto, Yusuke Sayama, Mayuko Saito, Mariko Saito-Obata, Clyde Dapat, Raita Tamaki, Christina Dahlia Joboco, Joanna Ina Manalo, Samantha Louise Bado, Joanne De Jesus Cornejo, Socorro Lupisan, Marianette Inobaya, Veronica Tallo, Beatriz P Quiambao, Hitoshi Oshitani

“…Another 10-month-long local circulation event, by definition, was more likely the result of two distinct introduction events with local circulation lasting less than 3 months, respectively. Most amino acid substitutions that emerged during local circulation were sporadic. …”
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Cardiovascular autonomic neuropathy defined by indices of heart rate variability is associated with cardiovascular disease: a longitudinal cohort study of participants with type 1... by Barbara H. Braffett, Laure El ghormli, Catherine Martin, Neil H. White, Irl B. Hirsch, Anne Bantle, Anders Carlson, Ellen Leschek, Rose Gubitosi-Klug, Elsayed Z. Soliman, Adrian Vella, Bruce A. Perkins, Ionut Bebu, Rodica Pop-Busui, for the DCCT/EDIC Research Group

“…Higher pulse rate (OR [95% CI] 1.08 [1.07,1.10] per 1 bpm) and HbA1c (1.43 [1.29,1.58] per 1%) were the most significant risk factors for CAN, followed by older age, male sex, higher albumin excretion rate, and hypertension history. …”
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Maximizing the scientific application of Pandora column observations of HCHO and NO₂ by P. Rawat, J. H. Crawford, K. R. Travis, L. M. Judd, M. A. G. Demetillo, L. C. Valin, J. J. Szykman, A. Whitehill, E. Baumann, T. F. Hanisco

“…This method suggests that standard PGN criteria for atmospheric variability and the normalized root mean squared error are too stringent, as they are responsible for downgrading most of the recovered data. A method is also developed for combining the direct-sun and sky-scan observations into a single dataset by accounting for biases between the two observing modes and differences in measurement integration times. …”
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Evaluation of the efficacy and safety of TACE combined with anlotinib and sintilimab in the treatment of patient with CNLC stage ⅡB-ⅢB liver cancer by TONG Gang, HUA Yang, PENG Wei, ZHAO Ju, HU Junwen

“…In recent years, tyrosine kinase inhibitor (TKI) alone or in combination with immune checkpoint inhibitors have achieved good results in the treatment of primary liver cancer. However, most studies did not include the combination of transcatheter arterial chemoembolization (TACE) treatment. …”
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EFFECT OF LISINOPRIL ON 24-HOUR BLOOD PRESSURE AND ARTERIAL STIFFNESS IN PATIENTS WITH ARTERIAL HYPERTENSION AND RHEUMATOID ARTHRITIS by O. L. Sarkisova, N. V. Rebrova, I. I. Bogomolova, E. A. Anisimova, R. S. Karpov, V. F. Mordovin, T. G. Khruleva

“…Atherosclerosis of carotid arteries with stenosis less than 25% was diagnosed in 65% of patients. Most patients had a positive rheumatoid factor and cyclic citrullinated peptide antibodies, as well as moderate RA activity and III-IV radiologic stage of RA. …”
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Utility of a Novel High‐Sensitivity Multiplex Companion Diagnostic Test Using Formalin‐Fixed Paraffin‐Embedded Cell Block Materials of Non‐small Cell Lung Cancer by Yoshiki Shinomiya, Yuko Ishida, Kanako C. Hatanaka, Mamiko Yamamoto, Ayae Nange, Asami Okumura, Yumi Wada, Mitsuharu Abiko, Tomohiro Shimizu, Ryoko Watanabe, Yamato Hashimoto, Yoshiharu Sato, Jun Sakakibara‐Konishi, Tatsuya Kato, Shinya Tanaka, Yutaka Hatanaka

“…To confirm that cPANEL has better sensitivity than single‐CDx, which has high detection power, and that it is advantageous in low TC samples such as FFPE‐CB, we compared the two CDx assays based on the EGFR‐positive rate using samples that did not meet the TC criterion for single‐CDx. Results Most FFPE‐CB had low TC levels, with only approximately 27% meeting the TC criteria for the widely used multi‐CDx. …”
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Clinical–pharmaceutical assessment of medication CDSS alerts: content appropriateness and patient relevance in clinical practice by Jacqueline Bauer, Marika Busse, Sonja Koch, Marina Schmid, Julia Sommer, Martin F. Fromm, Martin F. Fromm, Frank Dörje, Frank Dörje

“…The acceptance rate of interventions was 92.2% (225/244). The most common severity category was C (error occurred, no harm).ConclusionDespite the locally customized medication CDSS, a high number of CDSS alerts were displayed. …”
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PERIPROSTHETIC JOINT INFECTION IN PATIENTS WITH RHEUMATIC DISEASES: THE PROBLEMS OF DIAGNOSIS, PREVENTION, AND TREATMENT by A. E. Khramov, M. A. Makarov, E. I. Byalik, S. A. Makarov, B. S. Belov, V. P. Pavlov, A. V. Rybnikov, V. N. Amirdzhanova

“…One of the most menacing complications of large joint total endoprosthesis (TE) in patients with rheumatic diseases (RD) is the development of periprosthetic infection (PI), progression of which may give rise not only to limb loss, but also death. …”
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Comparative Analysis of Different Body Composition, Mucus Biochemical Indices, and Body Color in Five Strains of <i>Larimichthys crocea</i> by Hongjin Deng, Quanyou Guo, Banghong Wei, Jiehui Zhong, Mengyao Zheng, Yao Zheng, Na Lin, Shengyang Zheng

“…In conclusion, the LYC3 group’s crude protein, crude lipid, carotenoid, and lutein contents were most similar to those of the large yellow croaker found in the wild. …”
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The effect of chronic yoga interventions on sleep quality in people with sleep disorders: a scoping review by Mohammad Alghosi, Mohammad Alghosi, Maryam Sharifi, Sanam Namavari, Neda Rajamand, Faezeh Bamorovat, Narges Norouzi, Mohammad Alimoradi, Andreas Konrad

“…Long-duration interventions (≥17 weeks) produced the most robust results, with 100% of the studies reporting significant improvements, including a 7.92% increase in sleep quality (95% CI 3.23 to 12.60%). …”
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Interpersonal violence-related physical injury in low- and middle-income countries and its association with markers of socioeconomic status: a systematic review by Kevin J. Blair, Haley Tupper, Jordan M. Rook, Michael de Virgilio, Thiago S. Torres, Akshayaa K. Chittibabu, M. Wynn Tranfield, Bethany Myers, Alan Hubbard, Alain Chichom-Mefire, Mary-Margaret Ajiko, Catherine Juillard, Rochelle Dicker, Fanny Nadia Dissak-Delon

“…Brazil, Mexico, and South Africa were the most represented countries. Studies were mostly cross-sectional (n = 23), and data were typically from patient hospital records (n = 17) or population surveys (n = 12). …”
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Acceptability of an Intervention to Prevent Older Adult Mistreatment Among Family Caregivers to Persons With Dementia: Multimethod Pilot Study by Kylie Meyer, Wenxing Wei, Jeanine Yonashiro-Cho, Susanna Mage, Sohee Kim, Elliane Irani, Christopher Burant, Zachary Gassoumis, Erin Gentry Lamb, Jaclene A Zauszniewski, Donna Benton

“…Psychological mistreatment is the most common form of older adult mistreatment by family caregivers and is known to create mental health morbidities among care recipients. …”
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Non-English Students’ Perception of Lecturer’s CBT (Code Mixing, Body Moving, and Translating) Strategy of English Teaching by Arni Arsyad Sultan

“…Second, CBT is important affectively because it keeps them enthusiastic in which they can imitate English pronunciation. Third, in the most effective way, non-English students prefer “complexity” in which lecturer performs word verbally and nonverbally. …”
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Status and Best Management Practices of Potato Early Dying Disease in New Brunswick, Canada by Khalil I. Al-Mughrabi, Rene Poirier, Salah Eddin Khabbaz

“…Potato early dying (PED) disease complex is often called the <i>Verticillium</i> wilt of potato and is considered one of the most economically devastating diseases of potato worldwide. …”
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Avaliação de sintomas depressivos em pessoas com úlcera venosa Evaluation of depressive symptoms in patients with venous ulcers by Geraldo Magela Salomé, Leila Blanes, Lydia Masako Ferreira

“…All levels of depression showed statistical differences. The five symptoms most commonly found were sadness, distorted body image, self-depreciation, decreased libido, and social withdrawal. …”
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Spatially resolved proteomics surveys the chemo‐refractory proteins related to high‐grade serous ovarian cancer by Linyuan Fan, Yi Liu, Haichao Zhou, Yang Feng, Guangyi Jiang, Guixue Hou, Zhihan Cao, Zhiguo Zheng, Lu Sun, Hao Chen, Yuefei Zhang, Weiran Chen, Yun Xi, Benliang Cheng, Qinghai Yang, Yan Ren, Jianqing Zhu, Siqi Liu

“…Specific sampling revealed stroma‐driven tumour heterogeneity, identifying 642 tumour‐specific and 180 stroma‐specific proteins, with 505 CP‐responsive therapeutic targets. Most of these protein signatures represented previously unreported associations with chemoresistance in HGSCs. …”
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Tapering-pressure VAC therapy for wound exudation in POPF after pancreatoduodenectomy: a single-center experience by Guo-Hua Liu, Guo-Hua Liu, Zhen-Yue Xu, Jian-Hui Tan, Jia-xing Li, Jun-Er Xu, Xiao-Yu Tan, Jing-Wei Zhai, Jia-yuan Wu, Guo-Hui Zhong, Ming-Yi Li, Ming-Yi Li

“…However, postoperative pancreatic fistula(POPF) is the most intractable complication causing relevant mortality. …”
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Prevalence of epsilon toxin-producing Clostridium perfringens isolates among patients with multiple sclerosis and neuromyelitis optica spectrum disorder in Iran by Masoumeh Azimirad, Sara Hamtaeigashti, Hamideh Raeisi, Mehdi Azizmohammad Looha, Fatemeh Gholami, Abdorreza Naser Moghadasi, Mohammad Reza Zali, Abbas Yadegar

“…Among individual parameters, sex (AUC = 0.63) and IgG level (AUC = 0.57) were the most reliable predictors. The nomogram prediction demonstrated that the probability of patients’ risk of developing MS and NMOSD can be predicted using these predictors. …”
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