Can We Predict the Surgical Margin Positivity in Patients Treated with Radical Prostatectomy? A Multicenter Cohort of Turkish Association of Uro-Oncology by Deniz Bolat, Saadettin Eskiçorapcı, Erdem Karabulut, Sümer Baltacı, Asıf Yıldırım, Sinan Sözen, Ferhat Ateş, Çağrı Akın Şekerci, Fatih Kurtuluş, Ayhan Dirim, Talha Muezzioğlu, Cavit Can1, Murat Bozlu, Hakan Gemalmaz, Sinan Ekici1, Haluk Özen, Levent Turkeri

“…Conclusion Preoperative prostate specific antigen level, percentage of tumor involvement per biopsy specimen, surgical experience and nerve-sparing technique are the most important predictive factors of surgical margin positivity in patients undergoing radical prostatectomy for localized prostate cancer.…”
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A large language model based pipeline for extracting information from patient complaint and anamnesis in clinical notes for severity assessment by Hui Gao, Kaipeng Wang, Yuan Yuan, Yueguo Wang, Qingyuan Liu, Yulan Wang, Jian Sun, Wenwen Wang, Huanli Wang, Shusheng Zhou, Kui Jin, Mengping Zhang, Yinglei Lai

“…At later stage, vital signs became available, the enhancements in prediction attributable to the score were weaker, but still was observed with statistical significance in most cases. The recent LLMs are capable of extracting valuable information from clinical notes for identifying critical illness. …”
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Electrical and Viscoelastic Parameters of Erythrocytes as a Part of Diagnostic Models for Differentiating Fatty Liver Disease of Mixed Genesis from Non-Alcoholic and Alcohol-Relate... by M. V. Kruchinina, M. F. Osipenko, M. V. Parulikova, A. A. Gromov

“…The electrical and viscoelastic parameters of erythrocytes were investigated by the diagnostic technique of dielectrophoresis using an electrooptical cell detection system.Results. The most significant parameters for differentiating fatty liver disease of mixed genesis (metabolic + alcoholic) from NAFLD using the Volcano plot have turned out to be cell polarizability at a frequency of 106 Hz (p = 6.49 ×10-5), erythrocyte cell membrane capacity (p = 0.00077), relative polarizability (p = 0.001), the levels of which were higher in patients with NAFLD. …”
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Isolated Transpupillary Photodynamic Therapy in Local Treatment of Choroidal Melanoma by I. E. Panova, E. V. Boiko, E. V. Samkovich, V. G. Gvazav

“…Multivariate analysis of predictors of treatment efficacy reveal that the most significant criterion was the degree of CM vascularization (AUC = 0.906 (0.802; 1.000), p = 0.002). …”
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Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas by Zhiyong Wang, Zhiyong Wang, Guangai Deng, Guangai Deng, Chongyang Hu, Chongyang Hu, Xue Hou, Xue Hou, Xinyuan Zhang, Zhiquan Fan, Zhiquan Fan, Yong Zhao, Mu Peng, Mu Peng

“…Random forest analysis showed that soil TK and multiple elements [Cr, Ti, nickel (Ni), Ga and Se] were the most important predictors of bacterial diversity, emphasizing the role of multiple elements in shaping microbial communities. …”
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Usage of an App-Based Addiction Prevention Program for German Vocational Students: Secondary Analysis of Data From a Cluster Randomized Controlled Trial by Diana Guertler, Anne Möhring, Dominic Bläsing, Christian Meyer, Hannah Schmidt, Florian Rehbein, Merten Neumann, Arne Dreißigacker, Anja Bischof, Gallus Bischof, Svenja Sürig, Lisa Hohls, Susanne Wurm, Stefan Borgwardt, Severin Haug, Hans-Jürgen Rumpf

“…On average, participants started 4.8 (SD 5.1) and completed 4.3 (SD 5.2) of 16 weekly in-app chats. Most students (n=903, 71.3%) completed no self-initiated chats, and 50.2% (n=636) stopped using the app before week 3. …”
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Depression and anxiety in adolescents with cystic fibrosis in Brazil: prevalence, stability over time, and relationship with treatment adherence by Tatiana Rozov, Marcos Tadeu Nolasco da Silva, Maria Ângela Gonçalves Oliveira Ribeiro, Neiva Damaceno, Maria Angelica Pinheiro Santos Santana, Paulo Jose Cauduro Marostica, Roberta de Cássia Nunes Cruz Melotti, Valeria de Carvalho Martins, Carlos Antônio Riedi, Edna Lucia Santos de Souza, Norberto Ludwig Neto, Rodrigo Abensur Athanazio, Francyelly Wisnievski Yamamoto, Lusmaia Damaceno Camargo Costa, Sonia Mayumi Chiba, Izabela Sad, José Dirceu Ribeiro, Alexandra L. Quittner

“…Significant correlations were found between depression and anxiety at both time points, the associations being strongest at time point 1 (r = 0.68; p < 0.001). Most (66.7%) of the study participants reported low adherence to treatment, and the remainder reported either average adherence (in 28%) or high adherence (in 5.3%). …”
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Association Between Socio‐Economic Status (SES) and the Traditional Risk Factors of Cardiovascular Diseases (CVD): A Cross‐Sectional MASHAD Cohort Study Results by Fatemeh Sadabadi, Nasrin Talkhi, Mahyaar Omouri‐Kharashtomi, Mohammad Mirzaei, Sara Saffar Soflaei, Zahra Rahimi, Niloofar Shabani, MohammadReza Latifi, Mohammadreza Mohammadtaghizadeh Sarabi, Sarina Iri, Elham Moghaddas, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour‐Mobarhan

“…According to goodness‐of‐fit measures and entropy the three‐class model is the most optimal and suitable model here. Participants with a low SES had significantly lower means of age, physical activity level, waist circumference, systolic blood pressure and LDL‐C, and higher means of weight, and hip circumferences. …”
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Consistency of the orbital chronologies derived for Vostok and EPICA DC ice cores based on the dependence of ice air content on local insolation by V. A. Khomyakova, N. A. Tebenkova, V. Ya. Lipenkov, D. Raynaud

“…We prove that CWT analysis is the most reliable technique for tuning the experimental TAC records to their local summer insolation targets (ISI). …”
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The Effect of Automated Verbal Commands During Avalanche Transceiver Search on Acute Mental Stress and Arousal—A Mixed‐Methods Crossover Field Study by Bernd Wallner, Fabio Caramazza, Simon Woyke, Manuel Winkler, Ivo B. Regli, Peter Mair, Gabriel Putzer, Giacomo Strapazzon, Markus Falk, Hermann Brugger, Katharina Hüfner

“…VOICE navigation may be an interesting option for companion avalanche rescue since it helps to reduce mental stress and arousal, thereby leading to shorter search times. The most significant limitation of the study was the setting of an experimentally created avalanche scenario, which cannot fully replicate all the environmental and psychological factors of a veritable burial situation.…”
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Mathematical modeling of donor liver cooling during hypothermic perfusion by A. V. Bukharov, A. F. Ginevsky, I. S. Seregin, B. I. Yaremin, E. Yu. Anosova, B. I. Kazymov, M. S. Novruzbekov

“…Complete cooling of the organ in the proposed model occurs within 720 seconds, with significant temperature gradients observed between central and peripheral areas of the liver throughout most of the cooling process.Conclusions. Existing liver cooling methods require optimization to ensure uniform temperature distribution across all segments. …”
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Norbert Elias i les paradoxes educatives actuals Norbert Elias y las paradojas educativas actuales Norbert Elias and current educational paradoxes by Jordi (Collet i Sabé) Collet

“…The authors believe that this perspective, which seeks never to lose sight of the profound inter-relationship between social and personal, structural and psychological elements, might be of use in dealing with some of the tensions which currently exist both in the education system as such and in education in general (families, leisure, sport and so on) and how they relate to one another. After outlining the most significant features of Elias’ theoretical and analytical arguments, by way of a conclusion it presents three contemporary educational paradoxes which can be better and more fully understood through the theory of civilisation.…”
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Vector-borne pathogens in cats and associated fleas in southern Ethiopia by Marika Grillini, Hana Tadesse, Alessandra Mondin, Maria Luisa Menandro, Giovanni Franzo, Giorgia Dotto, Antonio Frangipane di Regalbono, Bersissa Kumsa, Rudi Cassini, Giulia Simonato

“…Molecular analysis of feline blood samples revealed Hepatozoon spp. as the most common pathogen (36.7%; CI:28.3–46.1%), followed by Rickettsia spp. (5.5%; CI: 2.5–11.5%), Bartonella spp. (2.8%; CI:0.9–7.8%), and Babesia spp. (0.9%; CI:0.2–5.0%); whereas fleas harbored mostly Rickettsia spp. (52.2%; CI:43.1–61.1%), followed by Bartonella spp. (6.1%; CI: 3.0–12.0%), and Hepatozoon spp. (0.9%; CI: 0.2–4.8%). …”
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Volatile metabolomics highlights tea trichome's positive contribution to aroma and quality of white tea by Dandan Qi, Min Lu, Yali Shi, Xingmin Zhang, Lin Yue, Houzhen Jia, Chunwang Dong, Huimin Liu, Changbo Yuan

“…Aroma modifiers were also affirmed, including β-myrcene, 2-ethyl-3,5-dimethyl-pyrazine, (E)-2-hexenal, dehydro-β-ionone, (Z)-6-nonenal, (E,E)-2,4-decadienal and benzeneacetaldehyde, which were shared by all samples in tea trichome and tea body. Notably, most of these key and modified aroma components showed higher relative contents and ROAVs in tea trichome than those in tea body. …”
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Educación a distancia durante el confinamiento: Principales afectaciones para el alumnado de un campus universitario en México / Distance Education during confinement: Main effects... by William Reyes, María Fabiola Sansores-Sabido

“…The findings confirm that four of the five most frequent affectations found in the literature were also present in the university students of the Campus in all their disciplinary areas, which confirms that it is essential to have holistic visions of distance learning in order to face the challenges that educational systems will face in the future.…”
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COL7A1 indicates crucial potential as a basal membrane-related prognostic biomarker and therapeutic target in lung adenocarcinoma by Jiao Zhang, Jiao Zhang, Jiao Zhang, Jiao Zhang, Jiao Zhang, Rui Zi, Ping Hu, Zongying Jiang, Ye Lv, Haixia Zhang, Yanjiao Zhao, Yan Wang, Lujun Zhao, Lujun Zhao, Lujun Zhao, Lujun Zhao

“…IntroductionLung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer. Basal membrane (BM) is important to the invasive processes of LUAD. …”
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Systemic inflammation and morphofunctional parameters of myocardium and vessels in patients with combined course of chronic obstructive pulmonary disease and arterial hypertension by V. V. Kryvenko

“…Chronic obstructive pulmonary disease (COPD) is considered to be one of the most widely spread disease in the world. The main peculiarity of COPD is persistent airflow limitation that is usually progressive and associated with chronic inflammatory process in the airways. …”
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Estimation of SARS-CoV-2 mortality during the early stages of an epidemic: A modeling study in Hubei, China, and six regions in Europe. by Anthony Hauser, Michel J Counotte, Charles C Margossian, Garyfallos Konstantinoudis, Nicola Low, Christian L Althaus, Julien Riou

“…The case-fatality ratio (CFR), calculated from total numbers of reported cases and reported deaths, is the most commonly reported metric, but it can be a misleading measure of overall mortality. …”
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A Direct Comparative Analysis of HPV DNA with Single-Molecule RNA and p16INK4a Protein Expression in Lichen Sclerosus: Implications for Diagnostics and Pathogenesis by Georgios Kravvas, Boyu Xie, Clarisse Ganier, Henk van den Munckhof, Ellen van den Munckhof, Maurits de Koning, Sandra Jerkovic Gulin, Alex Freeman, Aiman Haider, Hussain Alnajjar, Asif Muneer, Magnus Lynch, Michael Millar, Aamir Ahmed, Christopher Barry Bunker

“…Various mucosal and beta HPV types were detected, most commonly HPV24, HPV23, HPV36, and HPV9. HPV DNA was found in all patients, and high-risk HPV types were found in 6. …”
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Application of intravascular physiology methods in clinical practice: two-year data from the Russian registry by V. V. Demin, A. M. Babunashvili, T. V. Kislukhin, E. Yu. Kostyrin, Z. Kh. Shugushev, V. N. Ardeev, E. V. Merkulov, Yu. G. Matchin, E. Yu. Gubarenko, N. A. Kochergin, S. P. Semitko, A. A. Anufriev, A. V. Ter-Akopyan, D. V. Teplyakov, O. E. Zauralov, G. K Arutyunyan, R. F. Atanesyan, D. A. Asadov, V. A. Ignatov, A. V. Azarov

“…All coronary arteries were examined, most often the anterior descending artery. As a primary diagnosis, 1968 (63,8%) studies were performed, while for the purpose of dynamic control — 122 (3,9%), at the surgical stage — 996 (32,3%). …”
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