Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut by Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin

“…In microarray analysis, the LCT gene was the most upregulated by PPARγ agonists in Caco‐2 cells. …”
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Nurse prescribing right: a bibliometric analysis by Yingying Wang, Yingying Wang, Ruixiao Jia, Su Gu, Zihan Wang, Liqun Zhu, Shaoyong Ma

“…At the same time, we sought to identify the most productive and influential countries/regions, institutions, journals, authors, research categories, keywords, and articles in the field of nurses’ prescribing rights. …”
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Design, synthesis, and in vitro antifungal evaluation of novel triazole derivatives bearing alkynyl side chains by Tingjunhong Ni, Lei Pang, Zhan Cai, Fei Xie, Zichao Ding, Yumeng Hao, Ran Li, Shichong Yu, Xiaoyun Chai, Ting Wang, Yongsheng Jin, Dazhi Zhang, Yuanying Jiang

“…In order to explore novel antifungal agents, twenty-seven triazole derivatives featuring an alkyne linker in the side chain were designed and synthesized by the Sonogashira reaction. Most of the target compounds exhibited good antifungal activity against eight human pathogenic fungi, especially excellent activity against Candida and Cryptococcus species, comparing with the reference drugs fluconazole, voriconazole and ravuconazole. …”
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Machine learning analysis of ARVC informed by sodium channel protein-based interactome networks by Yanan Zhu, Hui Zhang, Xuan Zhao, Xin Wang, Lina Xing, Sijie Yao, Xiao Jin, Tingting Li, Ting Dai, Xinyue Ding, Zhen Qi, Zongjun Liu

“…To validate these predictions, a series of experiments in cardiac organoids were conducted, including Western blotting, ELISA, MEA, and Masson staining to assess the effects of these compounds.ResultsWe first discovered and identified SCN5A as the most significantly affected sodium channel protein in ARVC. …”
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Psychometric properties of the rapid neurodevelopmental assessment in detecting social-emotional problems during routine child developmental monitoring in primary healthcare by Tia Campbell, Dianne C. Shanley, Marjad Page, Theresa McDonald, Melanie Zimmer-Gembeck, Megan Hess, Jodie Watney, Erinn Hawkins

“…Conclusions The single-item measures within the RNDA’s behaviour domain showed good convergent validity relative to the BASC-3. Most items had acceptable accuracy, comparable with similar screening measures. …”
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Critically ill patients undergoing interhospital transportation: a prospective multicentre cohort study in the Euregio Meuse-Rhine by Gernot Marx, Iwan C C van der Horst, Ulrich Strauch, Dennis Bergmans, Bas C T van Bussel, Stefan Beckers, Marc Felzen, Joachim Habers, Jochen Jansen, Micheline Christina Dionisius Maria Florack, Stephan Ortmanns, Marian Ramakers-van Kuijk

“…An intensivist accompanied most transports in the Netherlands, whereas various specialists transported patients in Germany. …”
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Results of candidemia treatment in children with hematologic malignancies: single center experience by I. I. Kalinina, D. D. Baydildina, E. V. Suntsova, O. V. Goronkova, L. A. Khachatryan, U. N. Petrova, G. G. Solopova, V. V. Sinitsina, G. A. Novichkova, M. A. Maschan, D. V. Litvinov, N. V. Myakova, G. A. Klyasova, A. A. Maschan

“…Candidemia is one of the most serious infectious complications in children with hematological malignancies and has a high morta lity rate.Seven-year experience of candidemia diagnosis and therapy in patients with various hematologic malignancies w as analyzed. …”
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Correlation Analysis between Household Hygiene and Sanitation and Nutritional Status and Female Leprosy in Gresik Regency by Flora Ramona Sigit Prakoeswa, Afik Zakie Ilhami, Ratna Luthfia, Aviola Syania Putri, Hardyanto Soebono, Dominicus Husada, Hari Basuki Notobroto, Muhammad Yulianto Listiawan, Anang Endaryanto, Cita Rosita Sigit Prakoeswa

“…Leprosy attacks various parts of the body including nerves and skin. The most important factor in the occurrence of leprosy is the sources of transmission and contact, both from patients and the environment. …”
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Low-pressure exposure influences the development of HAPE by Wang Bo, Hou JinXiu, Li Jing, Pei Shuaijie, Xie Keliang, Liu Wenbo

“…The HH group exhibited the most severe histopathologic abnormalities that included septal rupture. …”
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A new section of shoulder magnetic resonance imaging (MRI) used to assess the fat infiltration of the rotator cuff muscles by Guoyin Zhang, Qi Hu, Jianmin Zhang, Li Ying, Dawei Hang, Xiaobo Zhou, Qingguo Zhang

“…In the group with the most severe rotator cuff tear retraction, there was a significant difference in the degree of fat infiltration between Y view and r view (P < 0.01). …”
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Arthroscopic Superior Capsular Reconstruction With Knotless Double-Row Dermal Allograft and Margin Convergence Augmentation by Jonathan D. Groothoff MA, Thomas W. Mason BS, Anthony P. Fiegen MD, Jelle P. van der List MD PhD, Brian R. Waterman MD

“…Results: Complication rates following SCR vary. The most common complication is graft retear, which typically occurs at the medial anchor. …”
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Spatially and Seasonally Differentiated Response of Soil Moisture Droughts to Climate Change in Germany by Friedrich Boeing, Sabine Attinger, Thorsten Wagener, Oldrich Rakovec, Luis Samaniego, Stephan Thober, Julian Schlaak, Sebastian Müller, Claas Teichmann, Rohini Kumar, Andreas Marx

“…We show that projections of future changes in soil moisture droughts over Germany depend on the emission scenario, the soil depth and the timing during the vegetation growing period. Most robust and widespread increases in soil moisture drought intensities are projected for upper soil layers in the late growing season (July–September) under the high emission scenario. …”
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Thermal Accumulation Mechanisms of Deep Geothermal Reservoirs in the Moxi Area, Sichuan Basin, SW China: Evidence from Temperature Measurements and Structural Characteristics by Wenbo Yang, Weiqi Luo, Simian Yang, Wei Zheng, Luquan Zhang, Fang Lai, Shuang Yang, Zhongquan Li

“…Reservoir geothermal gradients (25.05–32.55 °C/km) exceed basin averages. (2) Transtensional strike-slip faults form E-W/NE/NW networks; most terminate at the Permian Longtan Formation, with few extending into the Lower Triassic while penetrating the Archean–Lower Proterozoic basement. (3) Structural highs positively correlate with higher geothermal gradients. (4) The deep geothermal reservoirs and thermal accumulation mechanisms in the Moxi area are jointly controlled by crustal thinning, basement uplift, and structural architecture. …”
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Developing drug-like single-domain antibodies (VHH) from in vitro libraries by M. Frank Erasmus, Andre A. R. Teixeira, Esteban Molina, Luis Antonio Rodriguez Carnero, Jianquan Li, David Knight, Roberto Di Niro, Camila Leal-Lopes, Adeline Fanni, Hallie Troell, Ashley DeAguero, Laura Spector, Sara D’Angelo, Fortunato Ferrara, Andrew R. M. Bradbury

“…A broad diversity of high affinity (100 pM-10 nM), developable binders was directly isolated, with developability evaluated for most assays using the isolated VHHs, rather than fused to Fc, which is customary. …”
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PTBP1 promotes IRES-mediated translation of cyclin B1<?A3B2 ACK?>in cancer by Fan Xinyi, Zhao Zitong, Ma Liying, Huang Xuanlin, Zhan Qimin, Song Yongmei

“…Interacting trans-acting factors (ITAFs) are required by most IRES to initiate the translation. We find that PTBP1 promotes the IRES-mediated translation of cyclin B1 by binding to the 5′UTR of cyclin B1. …”
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Investigating the Physical Adsorption of DCPD/Furfural and H₂ Adsorption–Dissociation Behaviors in RE-MOFs by Muye Niu, Zuoshuai Xi, Chenhui He, Wenting Ding, Shanshan Cheng, Juntao Zhang, Hongyi Gao

“…Notably, the structure identified as “JALLEQ_clean” exhibited the most optimal overall adsorption performance. This study elucidates the quantitative relationship between the pore structure of RE-MOFs and their physical adsorption performance, clarifying the influence of porosity parameters on adsorption capacity and highlighting the advantages of cluster-type structures in mass transfer and adsorption. …”
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Reliable estimation via hybrid gradient boosting machine for mud loss volume in drilling operations by Xiaozhi Lu, Farag M. A. Altalbawy, Tarak Vora, R. Manjunatha, Debasish Shit, Shirin Shomurotova, Akshay Kumar, Atreyi Pramanik, Ajay Sharma, Raed H. C. Alfilh, Samim Sherzod, Mohammad Mahtab Alam

“…Feature importance assessed through SHAP analysis revealed that hole size, formation type, and pressure differential were the most influential variables, while solid content had minimal effect.…”
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Modelo experimental para estudo de desenluvamento cutâneo no membro inferior Experimental model of degloving injury in hind limb by Dimas Andre Milcheski, Marcus Castro Ferreira, Paulo Tuma Jr, Hugo Alberto Nakamoto

“…Skin flap deffating and grafting of the detached flap have the disadvantages of resulting in poor aesthetic appearance and being less protective, but they have been the most widely used due to the higher rate of graft take. …”
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A Conservation Assessment and Phylogenomic Evaluation of Protection Status in the Tropical Genus Heliconia L. (Zingiberales: Heliconiaceae) by W. John Kress, Tomáš Fér, Mónica M. Carlsen, Gary A. Krupnick

“…Among threatened species, all but one are in five or fewer protected localities; most non‐threatened species (61%) are in five or more protected localities. …”
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Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report by Lina Feng, Lina Feng, Lina Su, Jingyi Ren, Jingyi Ren

“…After a comprehensive evaluation, a CCM device was implanted as the most effective and evidence-based option. Postoperatively, the patient's blood pressure gradually improved, allowing initiation of the four major therapeutic drug classes, which were uptitrated to the maximum tolerated doses. …”
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