A lentiviral vector targeting a KRAS neoepitope for cancer immunotherapy by Anastasia Goloudina, Fabien Le Chevalier, Pierre Authié, Sylvain Ciret, Kirill Nemirov, Ingrid Fert, Fanny Moncoq, Benjamin Vesin, Amandine Noirat, Catherine Blanc, Yu Wei, Pierre Charneau, Laleh Majlessi

“…The KRAS amino acid substitutions at the positions 12 or 13 are among the most frequent mutations in human cancers. Here, we developed immuno-oncotherapeutic non-integrative lentiviral vectors encoding a segment encompassing KRASG12D, either alone, or associated with antigen carriers. …”
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Optimizing deep learning models to combat amyotrophic lateral sclerosis (ALS) disease progression by Haoshen Qin, Lal Hussain, Ziang Liu, Xu Yan, Fuad A. Awwad, Faisal Mehmood Butt, Umair Ahmad Salaria, Emad A.A. Ismail

“…Feature importance analysis with optimized XGBoost identified ZBTB2P1 as the most influential feature, followed by RNF181, with WASH9P being the least influential among the top eight. …”
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Relationships between structure and properties in commercial lead zirconate titanate (PZT) piezoceramics by Xuyao Tang, Zimeng Hu, Vladimir Koval, Harry Baxter, Mirva Eriksson, Richard Whiteley, Krishnarjun Banerjee, Giuseppe Viola, Bin Yang, Haixue Yan

“…Lead zirconate titanate (PZT) ceramics are the most widely used commercial piezoelectric ceramics. …”
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Characterizing the Journey of Early Alzheimer’s Disease in Patients Initiating Lecanemab Treatment in the United States: A Real-World Evidence Study by Marwan N. Sabbagh, Chenyue Zhao, Malena Mahendran, Se Ryeong Jang, François Laliberté, Hideki Toyosaki, Kaixin Zhang, Feride Frech, Kavita V. Nair

“…Results Of 3155 patients included in the study, mean age was 75.0 years, 55.8% were female, 44.2% were male, and most (93.3%) received their index lecanemab administration in an urban setting. …”
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Solar Radio Burst Detection Based on Deformable DETR by Mingming Wang, Guowu Yuan, Hao Zhou, Chengming Tan, Hao Wu

“…The main challenges faced are noise interference in the spectrum and the diversity of SRBs. However, most research focuses on classifying whether SRBs exist or detecting a single type of SRB. …”
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Protecting the Orthopaedic Surgeon: An Institutional Review of Radiation Safety Practices, Knowledge, and Risks by Marfred M. Umanes, MS, Elizabeth O. Clayton, MD, Brenda Iglesias, MD, Emily A. Whicker, MD, Z. Deniz Olgun, MD, William Donaldson, MD, MaCalus Hogan, MD, MBA, FAOA

“…Orthopaedic surgeons are among the top 3 medical professionals most exposed to ionizing radiation and must minimize the risks of ionizing radiation to patients, themselves, and staff. …”
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The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII by Alessandro Bonardi, Silvia Bua, Jacob Combs, Carrie Lomelino, Jacob Andring, Sameh Mohamed Osman, Alessandra Toti, Lorenzo Di Cesare Mannelli, Paola Gratteri, Carla Ghelardini, Robert McKenna, Alessio Nocentini, Claudiu T. Supuran

“…X-ray crystallography studies were performed to investigate the binding mode of four TTIs in complex with a hCA IX mimic. The ability of the most potent and selective TTIs to reduce in vitro the viability of colon cancer (HT29), prostate adenocarcinoma (PC3), and breast cancer (ZR75-1) cell lines was evaluated in normoxic (21% O2) and hypoxic (3% O2) conditions demonstrating relevant anti-proliferative effects.…”
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Effects on quality of crayfish (Procambarus clarkii) meat treated with different thermal processing methods by Liu Du, Xuan Liu, Chuanfeng Hu, Dongyin Liu, Yu Qiao, Wei Yu

“…Among the four methods, HS was most effective in retaining volatile flavor compounds. …”
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Alterations in serum exosomal miR-1207-5p levels reflect severity and progression risk in type 2 diabetic kidney disease by Xiaochun Zhou, Jing Zhao, Jianqin Wang, Kaiying He, Hongxuan Du, Qicai You, Wenjiao Gu, Haiyu Niu, Qiaoying Jin, Yuke Kong, Futian Tang

“…Results miR-1207-5p was downregulated in the DKD patients compared to the controls, and this downregulation was the most prominent in the high-risk group. Correlation analysis revealed inverse associations between miR-1207-5p and parameters of renal dysfunction. …”
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Chinese Economic Diplomacy before and during the COVID-19 Pandemic by E. I. Safronova

“…The Silk Road Fund and the Regional Comprehensive Economic Partnership (RCEP) as well as the mega-project ‘The Silk Road Economic Belt and the 21st-century Maritime Silk Road’ are the most striking examples of the latter trend. Incentive economic diplomacy also serves as an important tool for strengthening the soft-power potential of the PRC in the international arena, especially in developing countries. …”
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Long-term Results of Drug and Interventional Treatment in Patients with Morphologically Verified Idiopathic Arrhythmias by O. V. Blagova, A. V. Nedostup, E. A. Kogan

“…Anti-heart antibodies were the most important in myocarditis diagnosis and monitoring. …”
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Frequency, barriers and facilitators of adherence to treatment among people with systemic lupus erythematosus in China: a scoping review by Yu Wang, Ning Liu, Zhang Feng, Xiao Ying, Wu Peiyu

“…Data were charted independently by two reviewers.Results 21 studies met inclusion criteria. Adherence was most often measured via self-report, especially Morisky Medication Adherence Scale-8 and Compliance Questionnaire for Rheumatology. …”
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Comparative analysis of the frequency of complications in one-stage and two-stage breast reconstruction after subcutaneous/skin-saving mastectomy in combination with radiotherapy by F. Kh. Shidakova, V. A. Sobolevskiy, R. M. Dokolin, M. B. Kurbanova

“…Reconstruction with endoprostheses is the main method, it accounts for up to 70 % of all reconstructive breast surgeries. Until recently, the most popular method was a two-stage reconstruction. …”
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Retalho fasciocutâneo bipediculado para tratamento de meningomieloceles Bipedicled fasciocutaneous flap in the meningomyeloceles treatment by Murillo Francisco Pires Fraga, Daniel Mello, Luis Fernando Perin, Américo Helene Jr

“…<br>INTRODUCTION: Neural tube defects and associated tissues are classified as spinal dysraphism, being the most severe one the meningomyelocele. OBJECTIVES: To evaluate the efficacy of the bilateral bipedicled fasciocutaneous flap in the meningomyeloceles treatment. …”
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Dynamic synthesis and transport of phenazine-1-carboxylic acid to boost extracellular electron transfer rate by Feng Li, Baocai Zhang, Xizi Long, Huan Yu, Sicheng Shi, Zixuan You, Qijing Liu, Chao Li, Rui Tang, Shengbo Wu, Xingjuan An, Yuanxiu Li, Liang Shi, Kenneth H. Nealson, Hao Song

“…However, neither identifying the most efficient electron shuttle molecule nor programming its optimal synthesis level that boosts EET has been established. …”
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Influence of Gaussian noise and Levy noise on the phase dynamics of the ensemble of Kuramoto-like oscillators of first and second order by Arinushkin, Pavel Alekseevich, Kupriyanov, Vladislav Dmitrievich, Vadivasova, Tatjana Evgenevna

“…The purpose of this study is to determine the stability threshold of the dynamic modes of the ensemble of phase Kuramoto-like oscillators, describing the behavior of a simple power grid model with a ring topology, under the external influence of Gaussian noise and Levy noise, to evaluate the results and determine the threshold values of noise at which the considered dynamic model is the most sensitive to noise and demonstrates a change of the steady state.…”
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A Review of Research on the Resource Utilization of Pyrolysis of Decommissioned Wind Turbine Blades by Zhipeng Ma, Leying Qu, Ping Zhou, Zhanlong Song, Xiqiang Zhao, Wenlong Wang

“…Among existing treatment technologies, pyrolysis is considered the most promising. This paper, based on the Web of Science database, employs bibliometric methods to analyze research trends in this field. …”
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The Assessment Tools and Influencing Factors of Insomnia in Chinese Adolescents: a Scoping Review by YU Yuemin, MO Feifei, LI Lesi, PAN Jiyang

“…Cross-sectional studies were the most common method (15 studies) among the included research. …”
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Meals, mealtimes and moments for learning: assessment of quality in early childhood education and care services by Bonnie Searle, Sandy Houen, Sally Staton, Karen Thorpe

“… Abstract Objective: Early education and care (ECEC) is part of the everyday life of most children in developed economies, presenting exceptional opportunity to support nutrition and ongoing food preferences. …”
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Syntheses and crystal structures of 4-benzyl-1-ethyl-1,2,4-triazolium bromide and its corresponding NHC complexes of rhodium and iridium by Timothy G. Lerch, Daniel R. Albert, Michael Gau, Edward Rajaseelan

“…All structures exhibit non-classical hydrogen-bonding interactions with the most acidic hydrogen atoms in complexes 2 and 3 playing critical roles in the orientations of structural units.…”
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