Development of a multi-targeted real-time PCR assay for the detection of the grapevine pathogen Xylophilus ampelinus by Aleksander Benčič, Alexandra Bogožalec Košir, Janja Matičič, Manca Pirc, Neža Turnšek, Tanja Dreo

“…Results The newly designed real-time PCR assays were evaluated via high throughput testing for specificity and sensitivity and compared with a reference assay. The most promising assays were selected and validated in different grapevine tissues and included in a test performance study to validate their reproducibility and robustness. …”
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The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis by Qin Qi, Rui Zhong, Yan Huang, Yong Tang, Xiao-wen Zhang, Chang Liu, Chun-fang Gao, Lin Zhou, Jian Yu, Lu-yi Wu

“…Abstract Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The 5-methylcytosine (m5C) RNA methyltransferase NSUN2 is involved in cell proliferation and metastasis and is upregulated in a variety of cancers. …”
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Autism in the Faroe Islands: Diagnostic Stability from Childhood to Early Adult Life by Eva Kočovská, Eva Billstedt, Asa Ellefsen, Hanna Kampmann, I. Carina Gillberg, Rannvá Biskupstø, Guðrið Andorsdóttir, Tormóður Stóra, Helen Minnis, Christopher Gillberg

“…Childhood autism or autism spectrum disorder (ASD) has been regarded as one of the most stable diagnostic categories applied to young children with psychiatric/developmental disorders. …”
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Digital Franchising in the Age of Transformation: Insights from the Motivation-Opportunity-Ability Framework by Tung-Lai Hu, Chuang-Min Chao, Chien-Chih Wu, Chia-Hung Lin, Shu-Che Chi

“…The results indicate that expected external rewards (β = 0.456, <i>p</i> < 0.001) and platform support (β = 0.315, <i>p</i> < 0.001) are the most influential factors in shaping entrepreneurial intention. …”
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Physician perspectives in treating obesity: an insight from Pakistan by Fatima Ibrar, Farzana Shafqat, Faisal Ali, Maliha Aziz, Abdur Rehman, Saira Akhlaq, Muslim Atiq

“…Lifestyle modification was consistently rated as the most effective treatment across both groups. Medications and bariatric surgery were perceived as significantly less effective than lifestyle modification or surgery alone (p<0.001 for both comparisons). …”
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Criminal legal basis for an expedited trial procedure provided by the chapter 40 of the Russian Criminal Procedure Code by A. V. Boyarskaya

“…These categories are among the most complex in the science of criminal law.Conclusions. …”
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Seroprevalence of arboviruses in members of United Nations peacekeeping missions in the Central African Republic by Atanasievska-Kujović Sonja, Ristanović Elizabeta, Đorđevski Nikoleta, Živić Maja, Krstić Milena, Ljubenović Nenad, Mladenović Jovan, Trifunović Sofija, Marjanović Sonja

“…The number of seropositive individuals for arboviruses was 48 (35.3%). Most members, 23 (16.9%), were seropositive for the Dengue virus, slightly fewer for the Chikungunya virus, 14 ( 10.3%), and the fewest were seropositive for the Zika virus, 11 (8.1%). …”
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Using deep neural networks and LASSO regression to predict miRNA expression changes based on mRNA data by Franz Leonard Böge, Helena U. Zacharias, Stefanie C. Becker, Klaus Jung

“…Furthermore, we investigated whether data augmentation or separate models for data from diseased and non-diseased samples can improve the prediction performance.ResultsIn general, most settings achieved strong correlations at the Level of individual samples. …”
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Demography, emergency interventions and outcome after severe pelvic injuries: a two-decade registry study from South- Western Norway by Kenneth Thorsen, Pieter Oord, Jon K. Narvestad, Andreas Reite, Kjell E. Tjosevik

“…About 2/3 are men and transport related injuries are the most common mechanism of injury. Patients in need of emergency intervention are characterized by a high median ISS and concomitant high mortality. …”
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The Main Risks of an Еpidemic Emergency Associated with New Respiratory Viruses by S. S. Slis’, E. V. Kovalev, E. G. Yanovich, A. A. Kononenko, A. K. Noskov

“…Epidemic manifestations of diseases caused by new respiratory viruses, in most cases, cause a crisis in public health, which indicates the need for a comprehensive study of the features of their course, determination of criteria for the potential risk of an emergency of an еpidemic nature, which will make it possible to timely organize a complex of anti-epidemic (preventive) measures. …”
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Dr El Lahawi's Neurotube: 10 years of online neurology teaching experience by Mohammed El Lahawi

“…Due to the need for online teaching, Dr El Lahawi NeuroTube was established in 2015 under the theme of: ‘Neurology as easy as it can be’.Most medical students, residents and junior physicians do not have an opportunity for proper neurology teaching. …”
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Assessing the Techno-Economic Feasibility of Bamboo Residue-Derived Hard Carbon by Senqiang Qin, Chenghao Yu, Yanghao Jin, Gaoyue Zhang, Wei Xu, Ao Wang, Mengmeng Fan, Kang Sun, Shule Wang

“…This study presents a detailed techno-economic analysis of hard carbon production from bamboo residues across China’s ten most bamboo-rich provinces. Regional feedstock availability was estimated from provincial production statistics, while average transportation distances were derived using a square-root-area-based approximation method. …”
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Trends in Opioid and Non-opioid Prescriptions in Austria (2016–2021): A Nationwide Study on Utilization and Concomitant Benzodiazepine Use by Aylin Bilir, Lorenz Kapral, Andrea Michalek-Sauberer, Razvan Bologheanu, Felix Gruber, Oliver Kimberger

“…Conclusion Prescription opioid use decreased from 2016 to 2021, with tramadol representing the most prevalent opioid. The study revealed a strong link between opioid and benzodiazepine prescriptions and an association with persistent somatoform pain disorder, where opioid use is typically not recommended. …”
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Sex-specific risk signals and onset patterns of drug-induced peripheral neuralgia: a 20-year pharmacovigilance analysis based on FAERS real-world dat by Xianyan Wang, Min Deng, Wanjun Liao, Yiwen Quan, Xiaoxue Xu

“…Time-to-onset analysis showed most adverse events occurred early in treatment, as indicated by Weibull shape parameters (β &lt; 1) for all major drugs.ConclusionThis study revealed novel and sex-specific DIPN risk signals using large-scale real-world data. …”
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Narrow band imaging in detection of early laryngeal malignancy by Bharathi Mohan M, Leena Rajam, Vikram V J, Sathya Narayanan N, Ashwin P

“…Conclusion The laryngeal squamous cell carcinoma (SCC) is the most common malignant tumour in the head and neck region. …”
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Brain Network Analysis Reveals Age-Related Differences in Topological Reorganization During Vigilance Decline by Lingyun Gao, Rui Zhang, Mengru Xu, Yi Sun, Gang Li, Yu Sun

“…Specifically, significant deficits in nodal efficiency were revealed in most of the brain regions, and the frontal area exhibited significant age-by-time interaction effect, which was attributed to a significant decline in the elderly group. …”
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Research on Classification Criteria for the Reducibility and Irreducibility of Intertrochanteric Femoral Fractures by Fenghua Zhu, Jinya Qiu, Liang Han, Hongxing Xu, Longtao Xiao, Qiushun Zhang, Yifeng Zhao

“…Conclusion Classifying intertrochanteric fractures into reducible and irreducible types can accurately preoperatively predict the difficulty of reduction for the vast majority of reducible fractures and most irreducible fractures, guide treatment, and predict the prognosis of the fracture.…”
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Meta-analysis of the effectiveness of exercise as an intervention for suicidal tendency in depressed patients by Wenli Wang, Hairong Liu, Qiangming Feng, Yuanming Peng, Yanran Si

“…Through subgroup analysis, it was found that the most beneficial intervention for physical exercise to relieve depressive symptoms was ≥3 times/week, lasting &gt;30 min over &lt;12 weeks, and combining various forms of aerobic exercise. …”
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Potential Use of Selected Natural Anti-Microbials to Control <i>Listeria monocytogenes</i> in Vacuum Packed Beef Burgers and Their Impact on Quality Attributes by Angelos Papadochristopoulos, Joseph P. Kerry, Narelle Fegan, Catherine M. Burgess, Geraldine Duffy

“…Minimum inhibitory and bactericidal concentration (MIC and MBC) results for natural anti-microbials (carvacrol; essential oils of thyme, rosemary, clove and cinnamon; hop extract; cranberry extract; cranberry pomace; propolis extract; and chitosan sourced from both shrimp and mushroom) were used to select agents (n = 6) showing the most promise against <i>L. monocytogenes.</i> These agents, including chitosan from shrimp and mushroom (a novel source), and cranberry extract, were then tested against <i>L. monocytogenes</i> in vacuum packed beef burgers during chilled storage (3 ± 1 °C, 16 days). …”
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Investigating Physical and Mechanical Properties of Mahogany Root Wood (Khaya ivorensis) for its Utilization by Justine Wepia Apungu, Kwaku Antwi, Emmanuel Appiah-Kubi, Francis Kofi Bih, Joseph Zakaria

“…MOE recorded 6724.4 MPa, 9276.0 MPa and 10010.0 MPa, MOR was 54.3 MPa, 76.1 MPa, and 78.5 MPa, compressive strength parallel to the grain was 41.8 MPa, 54.4 MPa, and 59.2 MPa, shear strength values ranged from 14.3 MPa, 15.4 MPa, to 17.2 and Janka hardness from 3.81 kN to 4.01 kN for tree 1, 2, and 3. Most of the recorded root wood results weresimilar to those of the stem and branch wood, indicating that it was equally fit for structural purposes.…”
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