Photodynamic Efficiency of Xanthene Dyes and Their Phototoxicity against a Carcinoma Cell Line: A Computational and Experimental Study by Suelen T. G. Buck, Fernanda Bettanin, Ednilson Orestes, Paula Homem-de-Mello, Hidetake Imasato, Rommel B. Viana, Janice R. Perussi, Albérico B. F. da Silva

“…RB was the more cytotoxic dye against HEp-2 cell line and the most efficient photosensitizer in causing photoxidation of uric acid; nevertheless it was the only one characterized as being hydrophobic among the xanthenes studied here. …”
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Poly-IC enhances the effectiveness of cancer immunotherapy by promoting T cell tumor infiltration by Juan Wu, Hussein Sultan, Esteban Celis, Andres M Salazar, Valentyna I Fesenkova, Aaron E Fan, Diane Addis

“…Background Immunotherapies, such as immune checkpoint inhibitors and adoptive cell therapies, have revolutionized cancer treatment and resulted in complete and durable responses in some patients. Unfortunately, most immunotherapy treated patients still fail to respond. …”
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Predicting in-hospital mortality in ICU patients with lymphoma using machine learning models. by Ling Xu, Guang Tu, Zhonglan Cai, Tianbi Lan

“…SHAP analysis highlighted the critical role of BUN as the most important factor in mortality prediction, followed by platelets and PT. …”
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The Effectiveness of Cognitive-Behavioral Therapy by Group Method on The Amount of Stress, Anxiety and Depression and Pain Intensity of Patients with Chronic Musculoskeletal Pain by Akram Hemmatipour, Fatemh Karimi, Azam Jahangirimehr, Elham Abdolahi Shahvali, Mehdi Makvand

“…Background and Aim: One of the most important medical problems in the whole world is chronic pain, which affects millions of people every year and they are not provided with proper treatment. …”
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Results of Using Alternating Presentation of Stereostimuli in Children with Functional Scotoma in Non-Paralytic Strabismus by S. I. Rychkova, V. G. Likhvantseva

“…Our results suggest that even in patients with FS in non-paralytic strabismus, stereo perception is possible under the conditions of alternating presentation of stimuli with certain characteristics. In this case, the most likely appearance of a stereo effect with stimuli containing peripheral linear elements that create a stereo effect when presented in an alternating mode with an empty interval between monocular phases.…”
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Predicting disinfection by-products (DBPs) in supply water within a real water distribution network using an artificial neural network by F. Khan, M.F.R. Zuthi, M.S. Rahman, M.A. Akbor, M.D. Hossain, M.N.I. Bhuiyan

“…Performance analysis revealed that using all nine input parameters together resulted in the most accurate predictions of TTHM concentrations. …”
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Second malignancies in patients with deficient mismatch repair system/microsatellite instability-high colorectal cancer by Paul Franques, Pierre Moreau, Camille Evrard, Arnaud Chong-Si-Tsaon, Éric Frouin, Marie-Luce Auriault, Valérie Moulin, Audelaure Junca, Julie Godet, Lucie Lebeau, Roxane Aguillon, Gaëlle Tachon, Lucie Karayan-Tapon, David Tougeron

“…Background: Colorectal cancers (CRC) with deficient mismatch repair system and/or microsatellite instability-high (dMMR/MSI-H) phenotype represent about 12% of CRC. dMMR/MSI-H CRC is due to a germline mutation (Lynch syndrome, LS) or an age-related epigenetic mechanism, mostly by hypermethylation of MLH1 promoter (sporadic cases). …”
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Cicatricial Tracheal Stenosis — A Long-Life Journey by A. A. Pechetov, G. A. Vishnevskaya, D. A. Volchanski, A. N. Lednev, I. I. Danilov, N. V. Gulova

“…Functional diagnostic methods reveal a pattern of bronchial obstruction, which necessitates the administration of inhalation therapy using various groups of bronchodilator and anti-inflammatory medications. The most informative instrumental diagnostic techniques for tracheal diseases include laryngotracheoscopy and computed tomography.Conclusion. …”
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In patients’ words: natural language processing of reports from patients experiencing orofacial pain and dysfunction by Dominik A. Ettlin, Markus Wolf, Nikola Biller-Andorno, Gerold Schneider

“…Conceptual maps of the 200 most frequent words or expressions revealed occupational limitations as significant constraints and highlighted the patients’ need for understanding causes and diagnoses. …”
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Polarization Ratios of Turbulent Langmuir/ -mode Waves Generated by Electron Beams in Magnetized Solar Wind Plasmas by F. J. Polanco-Rodríguez, C. Krafft, P. Savoini

“…Indeed, it is demonstrated that linear mode conversion at constant frequency near ω _p of ${ \mathcal L }{ \mathcal Z }$ waves scattering on δn is the most efficient and fastest process to produce large polarization ratios in randomly inhomogeneous plasmas. …”
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Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications by Javad Sharifi-Rad, Cristina Quispe, Seyed Abdulmajid Ayatollahi, Farzad Kobarfard, Mariola Staniak, Anna Stępień, Katarzyna Czopek, Surjit Sen, Krishnendu Acharya, Karl R. Matthews, Bilge Sener, Hari Prasad Devkota, Celale Kırkın, Beraat Özçelik, Montserrat Victoriano, Miquel Martorell, Hafiz Ansar Rasul Suleria, Mohammed M. Alshehri, Deepak Chandran, Manoj Kumar, Natália Cruz-Martins, William C. Cho

“…Among them, Withania somnifera (L.) Dunal is the most widely addressed species from a pharmacological and agroindustrial point of view. …”
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Racial and ethnic disparities in pediatric firearm deaths persist in 2022 and 2023 by Rafael Klein-Cloud, Bailey Roberts, Emma Cornell, Colleen Nofi, Chethan Sathya

“…We aimed to examine recent trends in U.S pediatric firearm mortality, how they differ by intent, and identify which ages, and racial and ethnic groups have been most impacted over time. Methods The Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database was queried for mortalities in children aged 0–19 years from 2014–2023, and crude death rate was reported as number of deaths per 100,000 persons per year. …”
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The Population Dynamics of the Mediterranean Fruit Fly, Ceratitis capitata Wied. Diptera: Tephritidae in Some Fruit Orchards in Gaza Strip by Ahmad Saleh, Mohammad El-Hamalawii

“…The Medfly activity continued in most of the season, but decrease to a very low level in all studied locations during early spring months (February -March), due to the absence of host fruits and unfavorable climatic conditions. …”
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Beta cyclodextrin stabilized cupric oxide nanoparticles assisted thermal therapy for lung tumor and its effective in vitro anticancer activity by Anakha D. Rajeeve, Vyshnavi T. Veetil, Sabarinathan Palaniyappan, Ramasamy Yamuna, Vishal Bhalla

“…Our investigation revealed Case III, where the temperature distribution at the top surface of the tumor is best and may be the most effective way to treat lung cancer. It was found that an incident flux of 8000 Wm− 2 for 900 s and an extinction coefficient of 8.266 m− 1 for CuONPs@βCD were the best conditions for reaching a temperature of 43.63 °C across the whole tumor area. …”
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Ameliorating quality and vase life of Solidago canadensis flowers via supplementation of eucalyptus, neem and rosemary as phyto-preserver oils by Iman Mohamed El-Sayed, Rasha Ahmed Mohamed El-Ziat, Hani Saber Saudy, Mohammed Hewidy

“…Thus, neem oil at a concentration of 400 mg L–1 added to a preservative solution is considered the most promising practice for prolonging the vase life and maintaining high quality of Solidago.…”
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Achaete-scute complex homologue-1 promotes development of laryngocarcinoma via facilitating the epithelial–mesenchymal transformation by Huaci Ma, Xiaodong Du, Shu Zhang, Qiang Wang, Yong Yin, Xiaoxia Qiu, Peng Da, Huijun Yue, Hao Wu, Fenglei Xu

“…Laryngeal cancer is one of the most common fatal cancers among head and neck carcinomas, whose mechanism, however, remains unclear. …”
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High prevalence of Schistosoma mansoni infection and stunting among school age children in communities along the Albert-Nile, Northern Uganda: A cross sectional study. by Julius Mulindwa, Joyce Namulondo, Anna Kitibwa, Jacent Nassuuna, Oscar Asanya Nyangiri, Magambo Phillip Kimuda, Alex Boobo, Barbara Nerima, Fred Busingye, Rowel Candia, Annet Namukuta, Ronald Ssenyonga, Noah Ukumu, Paul Ajal, Moses Adriko, Harry Noyes, Claudia J de Dood, Paul L A M Corstjens, Govert J van Dam, Alison M Elliott, Enock Matovu, TrypanoGEN+ Research group

“…The majority of the children were underweight (BMI<18.5), and most notably, boys had significantly lower height for age (stunting) than girls in the same age range (p < 0.0001), but this was not directly associated with S. mansoni infection.…”
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Multifaceted Applications of Nanomaterials in Colorectal Cancer Management: Screening, Diagnostics, and Therapeutics by Xin H, Chang Z, Niu M

“…He Xin, Zhihui Chang, Meng Niu Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Meng Niu; Email nmeng_sjh@126.com Zhihui Chang, Email changzh@sj-hospital.orgAbstract: Colorectal cancer (CRC) is the third most common malignant tumor worldwide. Early detection and treatment of CRC can significantly improve patient survival and quality of life, while advanced-stage patients still face numerous challenges, such as drug resistance and adverse effects. …”
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Integrating ecological importance and risk for restoration zoning and ecological water demand in the Shiyang river basin by Yue Liu, Xuebin Zhang, Ziyang Wang, Haoyuan Feng

“…Results demonstrate: (1) The study area exhibits distinct southwest-northeast differentiation, with mountain, oasis, and desert systems predominantly represented by mountain and desert systems. (2) Ecosystem service importance displays “southwest-high, northeast-low” spatial patterns, increasing from 12.66 to 15.50 during the study period. (3) Ecological risk levels increase progressively across mountain, oasis, and desert systems, rising overall from 3.84 to 3.90, with oasis systems showing the most pronounced increases. (4) Based on ecological importance and risk assessment results, grid-scale ecological protection and restoration zones align closely with mountain-oasis-desert characteristics, providing clear management orientation. (5) Total ecological water requirements amount to 340.43 billion m³, displaying “south-high, north-low” patterns. …”
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Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients by Lihua Duan, Yan Huang, Qun Su, Qingyan Lin, Wen Liu, Jiao Luo, Bing Yu, Yan He, Hongyan Qian, Yuan Liu, Jie Chen, Guixiu Shi

“…Interleukin-33 (IL-33), the most recently discovered member of the IL-1 superfamily, has been linked to several human pathologies including autoimmune diseases, sepsis, and allergy through its specific IL-1 receptor ST2. …”
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