A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…EpCAM is an attractive therapeutic target because of its expression in most solid tumors. However, targeting EpCAM has been challenging because it is also highly expressed in normal epithelial tissues. …”
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Assessment of the Antibacterial Effect of the Oliveria decumbens vent. Essential Oil on Escherichia coli-induced Cystitis in the Rat Model by Hossein Antikchi, Seeyamak Mashhady Rafie, Negar Panahi, Pejman Mortazavi, kumarss amini

“…Antibiotic resistance is among the most concerning issues worldwide. Currently, the use of natural alternatives with improved therapeutic effects and fewer complications than common therapies is considered a novel therapeutic approach to care urinary tract infections (UTI). …”
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Respiratory Biomechanics, Intrapulmonary Water, and Pulmonary Oxygenizing Function During Uncomplicated Operations under Extracorporeal Circulation by I. A. Kozlov, A. A. Romanov

“…When cardiac surgery is uncomplicated and the AV and EC protocols are carefully followed, the rate of intraoperative POD is not greater than 20%, its leading causes are obesity and, most likely, microatelectasis under AV. Key words: pulmonary oxygenizing dysfunction, extracorporeal circulation, extravascular water of the lung, artificial ventilation, cardiosur-gical patients, pulmonary complications.…”
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Factors associated with frailty progression in community-dwelling older adults: A cross-sectional observational study by Yuko Sawada, Akihiro Kakuda, Emiko Tanaka, Etsuko Tomisaki, Taeko Watanabe, Munenori Matsumoto, Rika Okumura, Hiroshi Kinoshita, Tokie Anme

“…Significant differences among the robust, pre-frail, and frail groups were observed in most physical fitness and frailty-related items, particularly grip strength, walking ability, and lifestyle-related functions, except for cognition and depression. …”
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RISK FACTOR CONTROL IN PATIENTS WITH CORONARY HEART DISEASE – RESIDENTS OF A NORTH CAUCASUS REGION by R. T. Didigova, Z. Ugurchieva, A. M. Inarokova, M. N. Mamedov

“…Among CHD patients, hypercholesterolemia was the most prevalent risk factor in both men (95%) and women (81%). …”
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Glacier surface melt monitoring using Sentinel-1 SAR backscattering coefficient and polarimetric decomposition features at Greenland ice sheet by Huimin Jiao, Gang Li, Zhuoqi Chen, Xiao Cheng

“…Strong melting events occurred in 2019 and 2021, corresponding to the most recent extreme weather events. Compared to the National Snow and Ice Data Center (NSIDC) polar daily land freeze/thaw status product, our results revealed consistent spatial patterns of melting, showing discrepancy limited within ± 10 days, possibly due to the detecting penetration depth difference between Sentinel-1 and AMSR2.…”
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Short-term responses of ground-dwelling arthropod communities to habitat loss and fragmentation in experimental mesoscale landscapes by Cécile H. Albert, Olivier Blight, Benoît Geslin, Natan Huberson, Lenka Brousset, Hélène de Méringo, Victorine Demiralp, Matthieu Jurado

“…We expect detecting further effects in the years to come, as most species will have completed several life cycles. …”
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BAT-TR: Turkish Adaptation of Burnout Assessment Tool (BAT) by Ömer Erdem Koçak, Oğuz Gençay, Wilmar B. Schaufeli

“…It has been determined that the scale that has been used most frequently in the measurement of burnout has significant conceptual, technical, and application deficiencies. …”
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Nontuberculous mycobacterial infection after lung transplantation: a report of four cases by Naoko Ose, Masato Minami, Soichiro Funaki, Takashi Kanou, Ryu Kanzaki, Yasushi Shintani

“…Mycobacterium avium complex is the most common involved pathogen, followed by Mycobacterium abscessus (MABSC), while Mycobacterium kansasii is not a major concern. …”
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Quality and reporting of patient-reported outcomes in elderly patients with hip fracture: a systematic review by R Marijn Houwert, Marilyn Heng, Sandra Wilson, Puck van der Vet, Egbert-Jan Verleisdonk

“…PRO limitations were adequately reported in 20.9% of studies and interpretation of PROs was adequately reported in 19.4% of studies. Most Quality of Life (QoL) outcomes were measured by the EuroQol 5-Dimension 3-Levels, and pain as well as patient satisfaction by Visual Analogue Scale.Conclusion This study found that a high variety of PRO measures are used to evaluate geriatric hip fracture care. …”
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Characterizing the larval habitats of the main malaria vector, Anopheles stephensi, in southern Iran by Saideh Yousefi, Omid Dehghan, Madineh Abbasi, Ahmad Ali Hanafi-Bojd

“…Water temperature ranging from 12 °C in February to 35 °C in August, with significant correlations observed between warmer water temperatures and larval counts (p-value < 0.05). Most larval habitats were classified as temporary stagnant water bodies, with varying degrees of vegetation cover and substrate types. …”
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Lean Blow-Out analysis for the performance assessment of advanced burner designs operating under CO2-diluted air conditions using a high-fidelity CFD approach by Gianmarco Lemmi, Simone Castellani, Roberto Meloni, Sofia Galeotti, Antonio Andreini

“…Additionally, the findings highlight the most effective design strategy for extending the flame stability range under high EGR levels.…”
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Stress protection method for surgical treatment of patients with head and neck cancer by D. N. Vasiliev, D. E. Kulbakin, E. L. Choynzonov, S. V. Avdeev, D. Yu. Azovskaya, A. A. Lee, N. M. Khavkin

“…The surgical stage of treatment is the most important component of the combined method of treatment in cancer patients. …”
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Tracking spatio-temporal LULC changes in key ecological network elements using fragmentation metrics and a custom raster-based approach: A multi-scale study from Poland by Marta Kubacka, Witold Piniarski, Patryk Żywica, Amy E. Frazier

“…Division and effective mesh size (mesh) emerged as the most robust for multi-scale fragmentation assessment, with the mean shape index (shape_mn), largest patch index (lpi), and percentage of like adjacencies (pladj) providing complementary insights into patch complexity and connectivity trends. …”
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How Do Small and Medium-Sized Enterprises Create Value Through the Integrated Reporting Framework? Empirical Study on Integrity and Driving Factors by Ozlem Kutlu Furtuna, Asiye Zeynep Uykulu

“…The coal and lignite mining industry has the highest average alignment with the IR content elements, which is consistent with the view that the IR voluntary adoption should be adopted by the most polluting industries first. Regression analyses demonstrate that SMEs with a higher proportion of institutional investors are more willing to disclose content elements to satisfy greater stakeholder scrutiny. …”
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Synthesis and evaluation of novel thiohydantoin derivatives for antidiabetic activity using in silico in vitro and in vivo methods by Asma Bukhari, Humaira Nadeem, Iqra Zulfiqar, Maira Anwar, Syed Muzzammil Masaud, Babar Murtaza

“…Molecular docking studies revealed strong binding affinities of derivatives towards α-glucosidase (PDB: 3wy1) and α-amylase (PDB: 3dhp), with FP4 exhibiting the most favorable interactions (− 7.8 kcal/mol with α-amylase and − 7.0 kcal/mol with α-glucosidase), involving hydrogen bonding and π-π stacking. …”
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Exploring the prognostic significance of vitamin D deficiency in pancreatic cancer: Disease progression and survival outcomes by Aladeen Alloubani, Baraa Abadalhaq, Amal Alshami, Diana Fakhory, Feras Abdalghani, Mallak Almasri, Maysa Alkouz

“…Background: Pancreatic cancer remains one of the most aggressive malignancies with limited treatment options and poor survival rates. …”
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Influence of the extracorporeal membrane oxygenation system centrifugal pump operation mode on blood damage by M. S. Isaeva, A. I. Petrov, Ye. P. Banin

“…Within the framework of this study, numerical modeling of the pump operation in different modes is carried out and an assessment of the corresponding change in the values of hemolysis and thrombosis is made. It is found that the most dangerous operating modes also change depending on the parameter under consideration: hemolysis demonstrated the greatest dependence on rotation rate, thrombosis — on flow rate. …”
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Economics students’ behavioural intention and usage of ChatGPT in higher education: a hybrid structural equation modelling-artificial neural network approach by Iddrisu Salifu, Francis Arthur, Valentina Arkorful, Sharon Abam Nortey, Richard Solomon Osei-Yaw

“…Among the various factors influencing behavioural intentions, hedonic motivation emerged as the most dominant. Moreover, behavioural intentions and facilitating conditions significantly drive students’ actual use of the ChatGPT. …”
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Comparative Study of Machine Learning Techniques for Predicting UCS Values Using Basic Soil Index Parameters in Pavement Construction by Mudhaffer Alqudah, Haitham Saleh, Hakan Yasarer, Ahmed Al-Ostaz, Yacoub Najjar

“…The results indicate that the ANN-based model provided the most accurate predictions for UCS, achieving an R² of 0.83, a root-mean-squared error (RMSE) of 1.11, and a mean absolute relative error (MARE) of 0.42. …”
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