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72441
Clinical characteristics and factors associated with the severity of hand, foot, and mouth disease in Mekong Delta, Vietnam
Published 2025-12-01“…Background Hand, foot, and mouth disease (HFMD) is a contagious viral illness caused by enteroviruses, potentially leading to severe complications like encephalitis, myocarditis, and acute pulmonary edema.Objective This study examines clinical features and risk factors for HFMD severity.Materials and Methods A cross-sectional analysis of 200 children under 16 years.Results Oral ulcers (78.0%) and erythematous rashes (64.0%) as the most common symptoms. High fever (≥39°C), fever lasting over two days, and myoclonus were frequently observed. …”
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72442
Antiviral activity of herbal extracts against the tick borne encephalitis virus (literature review)
Published 2017-09-01“…In general, the published works can be divided into two areas of research - the study of whole plant extracts and the study of the biological activity of the purified extract components. The most informative results can be obtained under certain conditions; for example, the study of both water extracts of plants and extracts with organic solvents, fractionation of the initial preparations with the detected antiviral activity followed by the concentration of the target substance; identification of an antiviral agent to obtain standardized drugs and preclinical testing in laboratory animals and cell cultures. …”
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72443
Characterization of anti-SARS-CoV-2 monoclonal antibodies focusing on antigen binding, neutralization, and FcγR activation via formation of immune complex
Published 2023-12-01“…It has been reported that FcγR-mediated immune-cell activation by immune complexes is involved in the promotion of immunopathology of COVID−19; therefore, differences in the FcγR-activation properties of anti-SARS-CoV−2 mAbs are among the most important characteristics when considering the clinical impacts of anti-SARS-CoV−2 mAbs.…”
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72444
High-resolution mapping of substantia nigra in Parkinson’s disease using 7 tesla magnetic resonance imaging
Published 2025-05-01“…We also explored correlations between these measures and the severity of residual motor symptoms in the on-medication state and other clinical variables. Differences were most notable in the nigrosomes within the pars compacta, with patients showing reduced neuromelanin signals and increased QSM values. …”
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72445
Age at release affects developmental physiology and sex-specific phenotypic diversity of hatchery steelhead trout (Oncorhynchus mykiss).
Published 2025-01-01“…Most steelhead trout hatcheries increase growth rate during rearing to produce and release yearling smolts for harvest augmentation, but natural steelhead exhibit variable age of smoltification, so this common rearing practice may not be ideal for programs focused on recovering imperiled wild stocks; therefore, it is important to investigate and compare alternative hatchery rearing methods that promote life history diversity. …”
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72446
Enhancing the Efficacy and Safety of Methotrexate Treatment: A Focus on Drug Interactions (Review)
Published 2024-10-01“…When co-administering MTX and medicines having clinically significant DDIs described in the literature, healthcare providers should consider the risk factors for each individual patient. The most significant risk factors include moderate to severe renal and hepatic impairment, older age, polypharmacy, and hypoalbuminemia.CONCLUSIONS. …”
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72447
Role of hydroxychloroquine in primary glomerular disease - a systematic review and meta-analysis of the current evidence
Published 2025-08-01“…Moderate to substantial heterogeneity (I² = 69–95%) was observed for proteinuria outcomes, but no heterogeneity was found for eGFR outcomes (I² = 0%). 69 adverse events were reported, of which gastrointestinal and mucocutaneous effects were the most common. Conclusion HCQ therapy for primary glomerular diseases showed a trend toward reducing proteinuria without significant effects on eGFR, with a better safety profile. …”
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72448
Recent advances in additive manufacturing for solar cell based on organic/inorganic hybrid materials
Published 2025-07-01“…This review outlines the superiority of AM compared with traditional solar cell manufacturing methods and highlights how AM has addressed specific challenges currently faced by solar cells. The most widely researched solar cell structures in recent years were briefly reviewed with summarizing their advantages and disadvantages. …”
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72449
Cardiac abnormalities induced by benzene exposure from the flaring disaster at the BP refinery plant in Texas City
Published 2025-07-01“…Regardless of the changes in their overall cardiac function, most benzene exposed subjects experienced some changes in various heart rate parameters such as P wave duration, PR interval, PR segment, QRS duration, QT interval, QTC interval, P wave axis, QRS axis, and T wave axis. …”
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72450
Lignin Waste Valorization in the Bioeconomy Era: Toward Sustainable Innovation and Climate Resilience
Published 2025-07-01“…Lignin, the most abundant renewable aromatic biopolymer on Earth, is rapidly emerging as a powerful enabler of next-generation sustainable technologies. …”
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72451
Comparative assessment of the depth of invasion of early-stage oral cavity carcinomas based on intraoral ultrasound and computerized tomography findings
Published 2023-01-01“…In determining the stage of OCC, the most widely applied methods are computerized tomography (CT) and magnetic resonance imaging (MRI), whose limitations can be overcome to some extent by using intraoral ultrasound (IOUS). …”
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72452
Do we recognize child witnesses of domestic violence as victims?
Published 2024-01-01“…However, some families can be the source of a child‘s most intense vulnerability. In these families, children may be exposed to different types of violence or may witness domestic violence. …”
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72453
Quality of life of ice hockey players after retirement due to concussions
Published 2020-09-01“…Results: A total of 76 players were assessed, on average of 5 years after their most recent SRC. Overall, retired players had a high burden of postconcussion symptoms and reduced QoL. …”
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72454
Economic burden of end stage renal disease: a case study in southern Iran
Published 2025-06-01“…Abstract Background The condition of renal failure is widely regarded as one of the most significant challenges currently facing public health and typically treated through hemodialysis. …”
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72455
Enhancing the Bioactive Properties of Sugarcane Vinegar Through <i>Caesalpinia sappan</i> Extract Supplementation: A Novel Approach for Functional Beverage Development
Published 2025-05-01“…Gas chromatography–mass spectrometry (GC-MS) analysis revealed unique volatile organic compounds (VOCs) that were present exclusively in the <i>C. sappan</i>-supplemented vinegars but absent in the control. Most notably, the supplementation of <i>C. sappan</i> extract at concentrations of 2 and 4 g/L substantially enhanced both the antioxidant capacity and antimicrobial activity of the resulting vinegars. …”
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72456
Deep-m6Am: a deep learning model for identifying N6, 2′-O-Dimethyladenosine (m6Am) sites using hybrid features
Published 2025-03-01“…To enhance computational efficiency and eliminate noisy or redundant features, a supervised SHAP (SHapley Additive exPlanations) algorithm is utilized, ensuring the selection of the most informative features. Finally, a multilayer deep neural network (DNN) is used as a classification algorithm for identifying m6Am sites. …”
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72457
The index endoscopic characteristics associated with gastric neoplasms in serial screening of upper gastrointestinal endoscopy
Published 2025-07-01“…Conversely, adenoma were most frequently detected within 1 year, comprising 63.6% (P < 0.05). …”
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72458
Interim Analysis of Outcome in Postoperative Cases of Squamous Cell Cancer of Oral Cavity Receiving Adjuvant Radiotherapy/Radiochemotherapy: An Observational Descriptive Study
Published 2025-01-01“…Introduction: Squamous cell carcinoma of the oral cavity and lip is the most common type of head-and-neck cancer in India. …”
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72459
Investigating the relationship between emotional intelligence and motivation to learn practical courses in architecture Case Study: Practical lessons. Faculty of Art and Architectu...
Published 2024-11-01“…This category is directly related to success in education, and even how students live in the future. Most people learn subjects through their emotional intelligence, as a result, it can be seen that by examining the relationship between these two subjects, it can be used to strengthen the sense of motivation for learning in the practical courses of architecture. …”
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72460
Global research pathways in rural microfinance: a bibliometric study based on web of science and Scopus database
Published 2025-04-01“…Findings The analysis indicates a marked upward trend in rural microfinance research, with performance analysis identifying the most productive countries, influential authors, key affiliations, and leading journals. …”
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