Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary by Serena Brundu, Virginia Napolitano, Giulia Franzolin, Ettore Lo Cascio, Roberta Mastrantonio, Gabriele Sardo, Eliano Cascardi, Federica Verginelli, Sergio Sarnataro, Gennaro Gambardella, Alberto Pisacane, Alessandro Arcovito, Carla Boccaccio, Paolo M Comoglio, Enrico Giraudo, Luca Tamagnone

“…However, by comparing the mutational landscape of CUPs with that of most other human tumor types, it emerged a consistent enrichment of changes in genes belonging to the axon guidance KEGG pathway. …”
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Differences in effects of varying compound extreme temperature and precipitation events on summer maize yield in North China by Zhongxian Liu, Rangjian Qiu, Qi Zhang

“…Air temperature and precipitation are the most important weather elements that influence maize growth and yield formation, especially under rainfed cultivation. …”
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Direct oral anticoagulants in deep vein thrombosis associated with inferior vena cava agenesis: A report of three cases and a systematic review by Nicola Osti, Vito Racanelli, Nicola Susca, Nicola Martinelli, Alberto Maino

“…Results: In addition to our 3 cases, we found data from 19 publications for a total of 30 patients with IVCA-associated DVT treated with DOACs (24 subjects treated with rivaroxaban, 8 with apixaban, and one with dabigatran). Most patients were males (72.7 %) with a median age at DVT onset of 26.0 years (min–max range 13–64 years). …”
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A structural–functional diagnostic of Mpumalanga’s agricultural education and training system by Tim Fry, Aldo Stroebel, Sarah Cardey

“…This research goes beyond previous studies that focus on local-level agriculture, the influence of extension officers, or commodity-specific insights. Further, most agricultural studies in Mpumalanga focus on linear-modelled developmental pathways, whilst this study extends research by evaluating how multi-actor access and capabilities influence outcomes and the development of disenabling or enabling environments for AET in Mpumalanga. …”
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Event segmentation in ADHD: neglect of social information and deviant theta activity point to a mechanism underlying ADHD by Christian Beste, Veit Roessner, Astrid Prochnow, Xianzhen Zhou, Foroogh Ghorbani, Bernhard Hommel

“…Background Attention-deficit/hyperactivity disorder (ADHD) is one of the most frequently diagnosed psychiatric conditions in children and adolescents. …”
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Hereditary diffuse gastric cancer associated with a novel germline variant c.1596G>A in the <i>CDH1</i> gene by A. M. Danishevich, T. S. Lisitsa, S. E. Nikolaev, I. S. Abramov, M. G. Filippova, N. I. Pospekhova, A. M. Stroganova, M. P. Nikulin, A. E. Kalinin, I. S. Stilidi, L. N. Lyubchenko

“…Gastric cancer is one of the most common malignancies worldwide. Approximately 10 % of patients with gastric cancer are characterized by accumulation of gastric cancer cases in their family. …”
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Continuous Patient-Independent Estimation of Respiratory Rate and Blood Pressure Using Robust Spectro-Temporal Features Derived From Photoplethysmogram Only by Muhammad Ahmad Sultan, Wala Saadeh

“…For fewer computations and accurate measurements of BP, the most significant features are selected using correlation and mutual information measures in the feature engineering part. …”
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Anionic cocogem surfactants containing propyl-2-ol groups: Synthesis, surface properties and antibacterial activity against SRB bacteria by Ravan A. Rahimov, Gulnara A. Ahmadova, Aygun M. Isayeva, Inara V. Rustamova, Durna B. Agamaliyeva, Fedor I. Zubkov

“…It was defined that cocogem surfactants have antibacterial properties against SRB, which is considered to be the most dangerous for the oil industry.…”
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Nomogram Development for Assessing Oncotype DX Recurrence Scores in Breast Cancer: A Chinese Population Study by Jiayin Song, Lin Yang, Zhengqi Feng, Liyu Jiang

“…ABSTRACT Background Breast cancer (BC) is the most prevalent cancer among women worldwide, with increasing incidence rates, particularly in China. …”
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Understanding and comparing HIV-related law and policy environments: cross-national data and accountability for the global AIDS response by Matthew M Kavanagh, Ellie Graeden, Mara Pillinger, Renu Singh, Stephanie Eaneff, Victoria Bendaud, Rico Gustav, Taavi Erkkola

“…Given progress in basic and implementation science, it would be tempting to believe most countries have adopted policies aligned with global norms, with a few outliers. …”
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A Retrospective Study Using Mentzer Index for Prevalence of Iron Deficiency Anemia among Infants Visiting Maternal Centers at the Age of One Year by Johnny Amer

“…Microcytic anemia due to iron deficiency is the most common type of anemia in children. In this study, we aimed to assess the Mentzer index used by the Ministry of Health (MOH) in Palestine as a useful tool in differentiating between iron deficiency anemia (IDA) and thalassemia. …”
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Antimicrobial Resistance Patterns, Extended-Spectrum Beta-Lactamase Production, and Associated Risk Factors of Klebsiella Species among UTI-Suspected Patients at Bahir Dar City, No... by Asmamaw Ameshe, Tigist Engda, Mucheye Gizachew

“…Beta-lactam drugs are used extensively to treat patients infected with Klebsiella, but most of the Klebsiella species are resistant to third- and fourth-generation cephalosporins and monobactams to which data are scarce in the study area. …”
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Pediatric emergency departments’ readiness for change toward improving suicide prevention: A mixed‐methods study with US leaders by Cadence F. Bowden, Diana Worsley, Jeremy M. Esposito, Gretchen J. Cutler, Stephanie K. Doupnik

“…Interviews with our convenience sample of 21 directors revealed varying suicide prevention practices and confirmed that standardization, evaluation, and quality improvement initiatives were needed at most institutions. Leaders reported a high interest in improving care. …”
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Matters of the heart: A scoping review toward better management of nontuberculous mycobacterial infections of cardiac devices by Rattanaporn Mahatanan, Maria Alkozah, Devin Lee, Anais A. Ovalle, Natalie B.V. Riblet, Elizabeth A. Talbot

“…Prosthetic heart valves (N = 61; 50 %) and CIED (N = 46; 38 %) were the most frequently associated cardiac devices. Favorable outcomes, defined as treatment complete and cure, were significantly associated with device removal after adjusting for age, gender, and device type (aOR 3.45, 95 %CI 1.30–9.14). …”
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Experimental investigation of a R290 domestic heat pump equipped with a thermoelectric-aided sub-cooler by M. Pendzialek, T. Özyıldız, R. Fingas, D. Sánchez, P. Aranguren, J. Smolka, M. Haida

“…The energy efficiency of heat pumps is an important factor for the sustainability and electrification of domestic heating, especially for the most common air-to-water heat pumps, which are a competitive solution to conventional heating methods. …”
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A study of hormone receptor status in breast carcinoma and use of HER2-targeted therapy in a tertiary care center of India by Sandeep Bhaskar, Kartick Rastogi, Shivani Gupta, Arpita Jindal, Aseem Rai Bhatnagar, Sandeep Jain

“…HER2/neu expression was significantly higher with large tumor size (P = 0.001), high tumor grade (P < 0.001), advanced stage (P = 0.001), greater number of positive lymph nodes (P = 0.02), and ER/PR negativity (P < 0.001). Conclusions: Most of the breast cancer patients are ER and/or PR positive and HER2/neu negative. …”
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Global trends in smoking-attributable rheumatoid arthritis burden: Insights from GBD 2021. by Kaibin Lin, Yang Yi, Xi Xu, Zheng Wang, Yiyue Chen, Jiafen Liao, Bing Zhou

“…<h4>Background</h4>Smoking is one of the most significant environmental risk factors for Rheumatoid Arthritis (RA). …”
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Measuring Experienced Utility in the Context of Health Economic Evaluation: A Narrative Overview by Damien S. E. Broekharst, Sjaak Bloem, Jeroen Luyten, Edward A. G. Groenland, Pieter T. M. Desmet, Patrick P. T. Jeurissen, Michel vanAgthoven

“…However, retrospective impact assessment emerged as the most promising one, although further scholarly inquiry is warranted to examine the theoretical and practical complexities of this approach within health economic evaluation.…”
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Evaluate the integrative effects of irrigation water level, furrow irrigation methods, and nitrogen fertilizer rate on tomato yield in semi-arid southern Ethiopia by Edmealem Temesgen Ebstu, Mekuanent Muluneh

“…The integration of 75 % MAD with 100 % NFAR under conventional furrow irrigation, and 100 % MAD with 100 % NFAR under alternative furrow irrigation, was most preferable. This approach resulted in no loss of nitrogen fertilizer and saved 25 % of irrigation water without reducing tomato yield. …”
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Basic characteristics and physiological index changes of Abies georgei var. smithii seedlings at different altitudes of Shergyla Mountain by LIU Jiming, XIN Fumei, YANG Xiaolin, ZHAO Kentian, JIA Liming

“…The southeastern of Qinghai-Tibet Plateau is among the highest forest line distribution areas and one of the most obvious climate change areas in the world. Understanding ecological and climatic indicators of the forest line in this area can offer a foundation for analyzing the possible changes in the future climate scenario. …”
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