Anthrax lethal toxin exerts potent metabolic inhibition of the cardiovascular system by Jie Liu, Zehua Zuo, Rasem Fattah, Toren Finkel, Stephen H. Leppla, Shihui Liu

“…Anthrax lethal toxin induces host lethality mostly by targeting the cardiovascular system. Although the enzymatic activity and the molecular targets of LT have long been known, the detailed mechanisms underlying cellular/tissue/organ toxicity are still poorly understood. …”
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Determination of malachite green in sediment by ultra performance liquid chromatography-mass spectrometry by Mei Guangming, Guo Yuanming, Zhang Xiaojun, Yan Zhongyong, Li Peipei, You Juju, Ding Yueping

“…During the past research, much more expensive materials such as cation exchange columns or alumina columns were mostly applied as solidphase extraction adsorbents to determine MG in aquatic products and water. …”
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Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy study. by Steven Kho, Labibah Qotrunnada, Leo Leonardo, Benediktus Andries, Putu A I Wardani, Aurelie Fricot, Benoit Henry, David Hardy, Nur I Margyaningsih, Dwi Apriyanti, Agatha M Puspitasari, Pak Prayoga, Leily Trianty, Enny Kenangalem, Fabrice Chretien, Valentine Brousse, Innocent Safeukui, Hernando A Del Portillo, Carmen Fernandez-Becerra, Elamaran Meibalan, Matthias Marti, Ric N Price, Tonia Woodberry, Papa A Ndour, Bruce M Russell, Tsin W Yeo, Gabriela Minigo, Rintis Noviyanti, Jeanne R Poespoprodjo, Nurjati C Siregar, Pierre A Buffet, Nicholas M Anstey

“…<h4>Methods and findings</h4>We examined spleen tissue in 22 mostly untreated individuals naturally exposed to P. vivax and Plasmodium falciparum undergoing splenectomy for any clinical indication in malaria-endemic Papua, Indonesia (2015 to 2017). …”
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Combining one and two photon polymerization for accelerated high performance (3 + 1)D photonic integration by Grabulosa Adrià, Moughames Johnny, Porte Xavier, Brunner Daniel

“…However, current fabrication technology is mostly constrained to 2D lithography, and thermal energy dissipation induced by switching electronic signal lines presents a fundamental challenge for truly 3D electronic integration. …”
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Characteristics of Chang 7 shale gas reservoirs in Triassic Yanchang Formation of Ordos Basin and its exploration and development prospects by Kai WU, Juanqin GAO, Guwei XIE, Weiwei YANG, Lirong LUO, Shanpeng LI

“…These source rocks are characterized by high organic content, with organic matter types mainly being type Ⅰ to Ⅱ1. The Ro values mostly range from 0.9% to 1.2%, indicating that they are in thermal maturity stage. …”
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Foodborne diarrhea cases among the 6–17 year-old population in Beijing sentinel hospitals from 2013 to 2022 by Chao WANG, Yanlin NIU, Tongyu WANG, Yangbo WU, Jinru JIANG, Xiaochen MA

“…The peak period for pathogen detection was from July to September each year, while norovirus was mostly detected in winter and spring. Logistic regression results showed that compared with the 15–17 year-old group, the 12–14 year-old group (OR=0.512, 95%CI: 0.326–0.804) had a lower risk of pathogen infection. …”
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Integration of histopathology, transcriptomics and non-targeted metabolomics reveals toxic effects of thiamethoxam under acute stress in mirror carp (Cyprinus carpio var. Longke-11... by Dongchang Guo, Wenyang Song, Manhong Liu, Haixia Jiang, Xiaolong Wang, Zhiying Jia, Bin Xu

“…Genes related to immune response and antioxidant stress were mostly downregulated, while genes related to inflammation and apoptosis were predominantly upregulated. …”
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Improving the use of patient-held records in the Emtshezi Subdistrict by T.P. Kerry

“…The Emtshezi Subdistrict forms part of the uThukela Health District of KwaZulu-Natal and lies 120 km northwest of Pietermaritzburg. The population is mostly rural. The major towns are Estcourt, Weenen and Winterton. …”
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Early-life immunomodulation by carvacrol delivered in ovo in broiler chickens by Mila M.Y. Meijer, Henry van den Brand, Chiara Palmieri, Shahram Niknafs, Asad A. Khaskheli, Eugeni Roura

“…Our findings suggest changes in immune parameters occur as the chicken develops, but these mostly do not interact with in ovo carvacrol treatment. …”
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Dynamics of Structural and Functional Changes of Patients with Dry Form Age-related Macular Degeneration after Double Filtration Plasmapheresis by A. A. Volozhev, A. N. Kulikov, A. N. Belskih, D. S. Maltsev, S. E. Bednova, E. N. Nikolaenko

“…There are risk factors of dAMD (age, heredity, lifestyle etc.) which can cause metabolic disorders, changes hemorheological parameters which promote activation of druseogenesis and as a result an angiogenesis. Mostly an outcome of dAMD is geographical atrophy and decrease of central visual acuity. …”
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Comparison of soluble ions in dust fall among various latitudes in western Iran by Nahid Mahmoodimahpash, Bubak Souri

“…Calculation of CD also showed that chemical characteristics of dust falls in the three stations were mostly similar (CD < 0.5). Correlation of CD between cations in Sanandaj and Khorramabad and the wind factor (r= 0.99, p < 0.05), anions of Sanandaj and Andimeshk and rainfall (r= 1, p < 0.01) and moisture factors (r= 0.89, p < 0.05), respectively, demonstrated that the meteorological factors influence chemical characteristics of dust fall particles. …”
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Process-based modeling of solar-induced chlorophyll fluorescence with VISIT-SIF version 1.0 by T. Miyauchi, T. Miyauchi, M. Saito, H. M. Noda, A. Ito, T. Kato, T. Matsunaga

“…We also found that the mean seasonal variability in the simulated SIFs was mostly consistent with the GOSAT SIF retrievals at the subcontinental scale. …”
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Imaging and Clinical Characteristics of 8 Cases of COVID-19 Complicated with Pneumomediastinum in Children by FU Qiang, REN Zuolei, LIN Zhiqiang, GONG Jianfeng, WANG Changzheng, WANG Ting, HU Yalan, TAN Jufang

“…Conclusion Children with pneumomediastinum complicated by COVID-19 were mostly pre-school or school-age children, rare in infants. …”
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Individual and demographic responses of the palm Brahea aculeata to browsing and leaf harvesting in a tropical dry forest of Northwestern Mexico by Franceli Macedo-Santana, Christa Horn, Tamara Ticktin, María Teresa Pulido Silva, Bryan A. Endress, Leonel Lopez-Toledo

“…Results At the individual level, the analyzed traits mostly increased as function of leaf harvest and browing, especially during the first two years. …”
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The content of free fatty acids in relation to electronic nose sensors responses and sensory evaluation of cheese in a lamb skin sack (Sir iz mišine) throughout ripening by Milna Tudor Kalit, Ivan Buntić, Giuseppe Morone, Ivančica Delaš, Samir Kalit

“…Electronic nose analysis showed very well differentiation of cheeses in various ripening stages and these results are mostly in accordance with the results of consumers’ sensory assessment and physicochemical analyses. …”
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Drug susceptibility testing of Nocardia spp. using the disk diffusion method by Clémence Prudhomme, Brune Joannard, Gérard Lina, Eleonore De Launay, Oana Dumitrescu, Elisabeth Hodille

“…Conclusions Although the FDA criteria were mostly unmet, disk diffusion DST was suitable to accurately categorize Nocardia isolates into interpretative categories for the aminoglycosides and imipenem only, excluding species N. farcinica and N. cyriacigeorgica.…”
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THE PREVALENCE OF ELEVATED LEVELS OF C-REACTIVE PROTEIN AND ITS ASSOCIATION WITH TRADITIONAL RISK FACTORS AND MORBIDITY AMONG RESIDENTS OF THE RUSSIAN FEDERATION (ACCORDING TO THE... by S. E. Evstifeeva, S. A. Shalnova, A. D. Deev, T. M. Gatagonova, A. Yu. Efanov, Yu. V. Zhernakova, V. A. Il'in, A. O. Konradi, V. A. Metelskaya, E. V. Oschchepkova, S. V. Romanchuk, O. P. Rotar, I. A. Trubacheva, E. V. Shlyakhto, S. A. Boytsov

“…Prevalence of elevated hsCRP in patients with traditional risk factors after adjustment for sex, age, and region of residence showed that the elevated hsCRP was mostly associated with metabolic factors and diseases that were characterized by systemic inflammation.Conclusion. …”
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Explosive injury. Anesthesia by S.M. Grytsenko, V.P. Gavrylyuk, B.A. Brik

“…Moreover, the hospital care is mostly provided in civilian hospitals located next to the combat operation zone. …”
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A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistan... by Marie-Eve Roy, Alain Zgheib, Nicoletta Eliopoulos, Borhane Annabi

“…Abstract Background The epidermal growth factor receptor (EGFR) plays a significant role in vasculogenic mimicry (VM), a process by which aggressive cancer cells within hypoxic solid tumors form blood vessel-like structures independent of endothelial cells. Mostly attributed to cancer stem cells (CSC), VM is strongly associated with chemoresistance and poor prognosis in glioblastomas (GBMs). …”
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Synergistic Effects of Lightning Activity and Other Disturbance Factors on NO2 in Yunnan and Its Surrounding Areas by ZHAO Pingwei, LI Liyin, WANG Jiani, REN Juzhang, CHEN Jing, ZHANG Yunqiu

“…In the dry season (November to April of the next year), the concentration of NO2 density is higher, and the rainy season (May to October) is lower, and the number of lightning is opposite. (2) From February to April, the NO2 column density in region A and region B has a significant positive spatial correlation with the number of fire points and anthropogenic CO2 emissions, respectively, but a significant negative correlation with the number of lightning. (3) Lightning activity is mostly accompanied by obvious rainfall (R≥1 mm). When the lightning activity is weak, the wet deposition effect of rainfall on the ground NO2 density is obvious, and the wet deposition effect of rain falling from the stronger lightning activity cannot completely offset the contribution of lightning to the increase of ground NO2 density. (4) The change of surface NO2 density during the first lightning from June to August is more regular than that from February to April, which shows that the ground NO2 density increases hourly in the first 6 hours and decreases slowly hourly in the last 3 hours. (5) The ground NO2 density on the lightning days in the two regions is generally higher than those on the days without lightning. …”
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