Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis by Joaquin Montilla-Rojo, Sanne Hillenius, Thomas F. Eleveld, Daniela C.F. Salvatori, Leendert H.J. Looijenga

“…Notably, recurrent chromosomal aberrations are also observed in human PSCs (hPSCs), mostly in chromosome 1, 12, 17, 20 and X, and have similarly been associated with the acquisition of a malignant phenotype in vitro, posing a risk to their potential clinical application. …”
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Effectiveness of a distance-learning vs standard training in the integrated management of childhood illnesses: a cluster randomized controlled trial by Saidul Abrar, Assad Hafeez, Sana Rahim, Suhail A. R. Doi, Muhammad Naseem Khan

“…Results Under-five children presented to the two arms were mostly similar in gender, age, duration of consultation with the healthcare worker, and presenting complaints. …”
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SELECTION CRITERIA OF COMPOUNDS FOR DEVELOPMENT OF HIGH-POTENT ANALGESICS AND OTHER CNS DRUGS by A. V. Sosnov, F. M. Semchenko, V. N. Tohmahchi, A. A. Sosnova, M. I. Vlasov, A. S. Radilov, D. V. Krivorotov

“…The data analysis shows need to replace some of traditionally used mostly natural and semi-synthetic narcotic analgesics (with low therapeutic index, unsatisfactory pharmacokinetics and severe side effects) to promising synthetic opioids and non-narcotic analgesics. …”
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How scale affects N2O emissions in heterogeneous fields of a diversified agricultural landscape by Isabel Zentgraf, Maire Holz, Oscar Rodrigo Monzón Díaz, Matthias Lück, Katja Kramp, Valerie Pusch, Kathrin Grahmann, Mathias Hoffmann

“…Hot moments accounted for 6–71% of total crop N2O emissions and were mostly driven by soil physical properties. On a small scale, soil texture and environment determined spatial heterogeneity of N2O emissions being more pronounced for sandier soils. …”
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Seasonal Variation in Volatile Profiles of Lemon Catnip (<i>Nepeta cataria</i> var. <i>citriodora</i>) Essential Oil and Hydrolate by Milica Aćimović, Biljana Lončar, Milica Rat, Mirjana Cvetković, Jovana Stanković Jeremić, Milada Pezo, Lato Pezo

“…While sesquiterpene hydrocarbons were mostly confined to the essential oil, the recovery oil was distinguished by a higher presence of monooxygenated and more hydrophilic terpenes. …”
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Hyperosmolar therapy for severe subarachnoid haemorrhage: a protocol for a multicentre prospective observational study (OSMO-SAH study) by Hao Zhao, Ning Wang, Xin Qu, Chunxiu Wang, Meng Qi, Yueqiao Xu, Lidan Jiang, Wenjin Chen, Weitao Cheng, Feng Shang, Xiaotong Fu, Rongcai Jiang

“…Mannitol and hypertonic saline (HTS) at different concentrations are commonly used in clinical practice, but evidence of their use is mostly derived from studies about traumatic brain injury. …”
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Oil Heterogeneity Characteristics of Low Oil Saturation Sandstone Reservoirs in M Area of Junggar Basin by HE Aoting, YAN Jianping, HUANG Lisha, DING Minghai, LUO Guangdong, SONG Dongjiang

“…Type I strips are mainly pure fine sandstone and coarse sandstone, with high structural maturity, large pore throat radius, good physical properties, porosity is greater than 11.0%, permeability is greater than 7.0mD; the type II strips fine sandstone and medium-fine sandstone are in the majority, and the porosity and permeability are distributed in 6.0% ~ 11.0% and 0.2 ~ 7.0mD; the type III strips is mostly fine sandstone (containing calcareous/argillaceous/silty), and the pores structure are not developed. …”
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Incidence, characteristics, and comorbidities of a complete unselected Danish cohort of patients with thymic epithelial tumors by Tine Østergaard, Caroline V.A. Bjerke, Eric Santoni-Rigui, Thomas H.L. Jensen, Katharina A. Perell, René H. Petersen, Peter M. Petersen

“…Tumors in Tumour, Node, Metastasis (TNM) stage I were diagnosed in 181 patients (64%) and were mostly thymomas (72%). Prior to TET diagnosis, 91 (32%) patients presented with autoimmune disorders (19% myasthenia gravis) and 82 patients (29%) had at least one cancer diagnosis. …”
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Akuisisi Foreground dan Background Berbasis Fitur DTC pada Matting Citra secara Otomatis by Meidya Koeshardianto, Eko Mulyanto Yuniarno, Mochamad Hariadi

“…Furthermore, image matting is one solution to improve the effect of image segmentation. Mostly, the matting process used scribbles or trimap as a constraint, which is done manually as called a supervised method. …”
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Coarse-Fine Tracker: A Robust MOT Framework for Satellite Videos via Tracking Any Point by Hanru Shi, Xiaoxuan Liu, Xiyu Qi, Enze Zhu, Jie Jia, Lei Wang

“…Traditional Multiple Object Tracking (MOT) methods in satellite videos mostly follow the Detection-Based Tracking (DBT) framework. …”
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Different Formulations of Levothyroxine for Treating Hypothyroidism: A Real-Life Study by Pierpaolo Trimboli, Lorenzo Scappaticcio, Annamaria De Bellis, Maria Ida Maiorino, Luisa Knappe, Katherine Esposito, Giuseppe Bellastella, Luca Giovanella

“…Hypothyroid patients are treated by sodium levothyroxine (LT4). Tablet is the mostly used LT4 formulation, and the fasting regimen is required for the absorption of active principle. …”
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The crossroads of anxiety: distinct neurophysiological maps for different symptomatic groups by Gerez M, Suarez E, Serrano C, Castanedo L, Tello A

“…Shorter ERP latencies were found in several individual patients, mostly from the OCD group. Hyperactivities were found at the right frontorbital-striatal network in OCD and at the panic circuit in PD.Conclusions: Our findings support diffuse cortical instability in AD in general, with individual differences in information processing deficits and regional hyperactivities in OCD and PD. …”
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Patient Disease Characteristics and Treatment Patterns in Mild–Moderate Psoriasis: Results from Real-World Clinical Practice in the United States (PROSPECT Study) by Emily J. Goddard, James M. Haughton, James E. Lucas, Sophie G. Barlow, Timothy P. Fitzgerald, Alexander M. Litvintchouk, David Wu

“…Cracked skin, redness, and tender skin (p < 0.001 for all) were more common among those diagnosed with moderate PsO. Both groups mostly received topical agents; however, those diagnosed with moderate PsO more commonly received systemic (p < 0.001) or biologic (p = 0.002) treatment. …”
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CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β by Cao Yuming, Chen Zhenlie, Qin Zihan, Qian Kaiyu, Liu Tongzu, Zhang Yuanzhen

“…Testicular seminoma is a relatively rare tumor which is mostly detected in male population aged from 15 to <sc>35 years</sc> old. …”
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In-vitro effect of aflibercept and dexamethasone on the expression level of genes associated with epithelial-mesenchymal transition in retinal pigment epithelial cells by M. Hossein Nowroozzadeh, Hajar Farvardin, Seyed Ali Nabavizadeh, Fatemeh Sanie-Jahromi

“…Aflibercept plus dexamethasone combination led to a gene expression profile mostly similar to dexamethasone alone. The combination treatment also had a significant increase in β-catenin gene expression. …”
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Epidemiological Situation of Schigеllosis in the Republic of Dagestan and Directions for Improving Epidemiological Surveillance by Z. G. Tagirovа, N. M-G. Zulpukarova, Z. M. Daniyalbekova

“…Since 2006, the incidence of bacterial dysentery in Russia has continued to decrease, in the Republic of Dagestan it is at a high level, exceeding more than 10 times the national average. Mostly children are sick (up to 75%). Cases of shigellosis are recorded throughout the year, the seasonal increase in the incidence in the summer and autumn is associated with the activity of the main transmission pathogens – water and food. …”
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Spatial–temporal distribution of farmland occupation and compensation and its impact on ecological service value in China from 1990 to 2021 by Yuhao Li, Shuhui Shangguan, Wenyu Li, Shuang Liu, Yijin Li, Rui Han, Jingwen Xu

“…However, current research on farmland occupation and compensation is mostly based on farmland area. The area occupied and compensated for by farmland in different regions is inconsistent, and using only net increase or decrease in area to represent farmland occupation and compensation cannot accurately and fairly compare the degree of farmland occupation and compensation between regions. …”
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Silencing circRNA-ZFAND6 induces trophoblast apoptosis by activating the mitochondrial pathway through the miR-575/SOD2 axis in unexplained recurrent spontaneous abortion by Wenting Wang, Linxiang Huang, Juan Lv, Zhijing Miao, Shuping Jin, Shan Li, Qing Cheng

“…Results We confirmed that circRNA-ZFAND6 was a stable circular RNA and was mostly localized in the cytoplasm. CircRNA-ZFAND6 was downregulated in placental villous tissues of URSA. …”
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Exploring potential of tobramycin complexes for combating biofilms: In silico and In vitro studies by Vividha Dhapte-Pawar, Bhumika Kothe, Rama Bhadekar

“…Nosocomial infections linked to medical implants, wound infections, and cystic fibrosis infections are mostly caused by biofilms linked to Pseudomonas aeruginosa. …”
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Unveiling the Interplay Between Dendritic Cells and Natural Killer Cells as Key Players in Leishmania Infection by Ana Valério-Bolas, Mafalda Meunier, Armanda Rodrigues, Joana Palma-Marques, Rui Ferreira, Inês Cardoso, Lis Lobo, Marta Monteiro, Telmo Nunes, Ana Armada, Wilson T. Antunes, Graça Alexandre-Pires, Isabel Pereira da Fonseca, Gabriela Santos-Gomes

“…Canine leishmaniasis is a global disease mostly caused by L. infantum. Dogs are recognized as a good reservoir since harbor the infection long before developing the disease, facilitating parasite transmission. …”
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