Patient Burden And Impact Of Moderate-to-Severe Atopic Dermatitis In the Spanish Healthcare System: The APOLO Cross-Sectional Study by Pablo De La Cueva Dobao, Laia Curto Barredo, Juan Francisco Silvestre Salvador, Esther Serra Baldrich, Pedro Herranz Pinto, Natalia Hernández Cano, Francisco Javier Ortiz De Frutos, Gastón Roustan Gullón, Rosa María Izu Belloso, Irene Arévalo Ortega, Alicia González Quesada, Manuel Galán Gutiérrez, Yolanda Gilaberte Calzada, Daniel Arumi Torredemer, Noelia Llevat Felius, Irene Hernández Martín, Francisco José Rebollo Laserna

“…AD also affected patients’ work/academic activities and sleep. The disease was mostly treated with topical corticosteroids (81.5%) and emollients (75.9%). …”
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Prevalence, awareness and therapeutic control of hypertension in Belgium: an opportunistic screening of nearly 6,000 participants during the May Measurement Month campaigns 2017–23... by D De Bacquer, S Bayet, A Bondue, F Brohée, S Brouwers, A Carlier, M Chabot, P Delmotte, B Falque, H Heuten, J Huart, J. M. Krzesinski, A Persu, T Robberechts, T Vanassche, E Van Der Beken, Ph Van de Borne, P Van der Niepen, B Van Nieuwenhuyse, J Vanparys, T. De Backer

“…Here we report on the results of the MMM campaign done in Belgium during the month of May in 2017, 2018, 2019, 2022 and 2023.Methods Participants ≥18 years were recruited through opportunistic sampling in 12 sites (mostly hospital entrances) across Belgium. Apart from standardised BP recordings by trained staff, data were collected on demographics, lifestyle factors and comorbidities. …”
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Molecular Docking, Dynamics, and Preclinical Studies Reveal Morin Hydrate as a Potent PPARγ and Nrf2 Agonist That Mitigates Colon Inflammation by Aya A. Touny, Balaji Venkataraman, Saeeda Almarzooqi, Rajesh B. Patil, Bhoomendra A. Bhongade, Miroslav Harjaček, Tahir A. Rizvi, Shreesh Ojha, Shamanth Neralagundi Harihar Gowdru, Sandeep B. Subramanya

“…The primary isotypes of PPARs are PPARα, PPARβ, and PPARγ. PPARγ is mostly expressed in adipose tissue and the colon. …”
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Self-reported frequency of handwashing among pet and non-pet owners in different situations: results of four surveys of the general adult population in Germany by Karolin M. E. Nettelrodt, Thomas von Lengerke

“…Handwashing frequency was operationalized for nine indications using the item “How often do you wash your hands in each of the following situations: ‘never/almost never‘, ‘seldom‘, ‘mostly‘, ‘always/almost always‘?”, with the latter defining compliance. …”
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Comparative Analysis of Japanese Quince Juice Concentrate as a Substitute for Lemon Juice Concentrate: Functional Applications as a Sweetener, Acidifier, Stabilizer, and Flavoring... by Vitalijs Radenkovs, Inta Krasnova, Ingmars Cinkmanis, Karina Juhnevica-Radenkova, Edgars Rubauskis, Dalija Seglina

“…Additionally, malic acid is a principal component of JQJC’s acidity, determined at 20.98 g 100 g⁻¹ of fresh weight (FW), while LJC mostly contained citric acid at a concentration of 30.86 g 100 g⁻¹ FW. …”
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Performance Investigation of Active, Semi-Active and Passive Suspension Using Quarter Car Model by Kyle Samaroo, Abdul Waheed Awan, Siva Marimuthu, Muhammad Naveed Iqbal, Kamran Daniel, Noman Shabbir

“…However, the results of this paper show that the performance gap between the semi-active and fully active suspension is quite small, and the semi-active suspension is mostly able to match and sometimes outperform the fully active suspension n in certain metrics. …”
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Positive allosteric regulation of PAC1-R up-regulates<?A3B2 ACK?>PAC1-R and its specific ligand PACAP by Fan Guangchun, Tao Zhengxin, Chen Shang, Zhang Huahua, Yu Rongjie

“…ChIP-sequencing and related bioinformatics analysis show that the downstream target genes regulated by the nuclear PAC1-R are mostly involved in the process of cellular stress and related to neuroprotection, neuronal genesis and development.…”
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Development and internal validation of a prognostic model for predicting tonic-clonic seizures during pregnancy in women with epilepsy by Yanru Du, Wenting Huang, Ying Wang, Jiahe Lin, Niange Xia, Zhenguo Zhu, Xinshi Wang, Yuchen Xu, Huiqin Xu

“…GiViTI calibration belt showed that the predicted risks of the WMU model were mostly consistent with the observed risks. In terms of DCA, the WMU model revealed the highest net proportional benefit for predicted probability thresholds between 10% and 90%. …”
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Lessons learned from COVID-19 modelling efforts for policy decision-making in lower- and middle-income countries by Jacinta Nzinga, Jacquie Oliwa, Fatuma Hassan Guleid, Raymond Cw Hutubessy, Brittany L Hagedorn, Collins J Owek, Justinah Maluni, Joyline Jepkosgei, Vincent O Were, So Yoon Sim

“…Participants included researchers and policy actors involved in COVID-19 evidence generation and decision-making. They were mostly from lower- and middle-income countries (LMICs) in Africa, Southeast Asia and Latin America. …”
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User Experience of a Semi-Immersive Musical Serious Game to Stimulate Cognitive Functions in Hospitalized Older Patients: Questionnaire Study by Laurent Samson, Lena Carcreff, Frédéric Noublanche, Sophie Noublanche, Hélène Vermersch-Leiber, Cédric Annweiler

“…Questionable to unacceptable consistency was found for the other UX dimensions. Participants were mostly active (23/60, 38%) and constructive (21/60, 35%). …”
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Robust Real-Time Cancer Tracking via Dual-Panel X-Ray Images for Precision Radiotherapy by Jing Wang, Jingjing Dai, Na Li, Chulong Zhang, Jiankai Zhang, Zuledesi Silayi, Haodi Wu, Yaoqing Xie, Xiaokun Liang, Huailing Zhang

“…Even under high noise conditions (<i>S</i>² = 25), errors for all data remained within 1 mm with tracking success rates mostly at 100%. In conclusion, the proposed markerless tracking method demonstrates superior accuracy, noise robustness, and real-time performance for lung tumor localization during radiotherapy. …”
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Seismic Response Analysis of Small Modular Reactor Containment Based on LRB and FPS Isolation Strategies by JI Xiaoyu1, CHEN Nanyu1, CHEN Mufeng2, ZHANG Shuaijun1, HOU Gangling1, CAI Xuesong1

“…In non-isolated structures, tensile damage is mostly concentrated at the connections between the bottom and the side walls. …”
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TAAR8 in the Brain: Implications for Dopaminergic Function, Neurogenesis, and Behavior by Taisiia S. Shemiakova, Alisa A. Markina, Evgeniya V. Efimova, Ramilya Z. Murtazina, Anna B. Volnova, Aleksandr A. Veshchitskii, Elena I. Leonova, Raul R. Gainetdinov

“…Meanwhile, other TAARs (TAAR2, TAAR5, TAAR6, TAAR8, and TAAR9 in humans) are mostly known for their olfactory function, sensing innate odors. …”
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TSUBASA study: evaluation of the quality and content of daily life of people with hemophilia A without factor VIII inhibitors on prophylactic treatment with emicizumab by Teruhisa Fujii, Keiji Nogami, Akihiro Sawada, Azusa Nagao, Chiai Nagae, Masanori Nojima, Nobuaki Suzuki, Mika Kawano, Tomomi Shimura, Yoshimasa Sugao, Kagehiro Amano

“…The 36-Item Short Form Health Survey scores were mostly unchanged across the study period and comparable with Japanese national standard values. …”
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Itraconazole Loaded Micelle Based on Methoxy Poly(Ethylene Glycol)-Poly(D, L-Lactic Acid) for Ocular Drug Delivery: In vitro and in vivo Evaluation by He J, Yang J, Liang Z, Zhang Z, Pu G, Dong F, Lu P, Xia H, Zhang J

“…Transcorneal studies indicated that the fluorescence intensity (FI) was mostly enriched in the corneal epithelium, which was reduced in the stroma. …”
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Accelerometer measured physical activity and the incidence of cardiovascular disease: Evidence from the UK Biobank cohort study. by Rema Ramakrishnan, Aiden Doherty, Karl Smith-Byrne, Kazem Rahimi, Derrick Bennett, Mark Woodward, Rosemary Walmsley, Terence Dwyer

“…However, uncertainty exists on whether the inverse relationship between PA and incidence of CVD is greater at the highest levels of PA. Past studies have mostly relied on self-reported evidence from questionnaire-based PA, which is crude and cannot capture all PA undertaken. …”
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Morpho-biochemical evaluation and biodiversity assessment of multi-origin apricot cultivars in Algeria by Kaouther Boutiti, Awais Ali, Ines Bellil, Douadi Khelifi

“…Fruit quality is a major concern for distributors, producers, and consumers alike, and it is mostly determined by facets related to nutrients and taste. …”
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Structural and functional changes of the heart and electrical disorders in patients with coronary artery disease with concomitant anemia by M. O. Konovalova, N. S. Mikhailovskaya

“…The patients of both groups mostly showed diastolic dysfunction type 1, however, in the main group, there was a tendency to increase the number of patients with diastolic dysfunction type 2 and type 3. …”
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Evaluating the Effect of Fertilization and Substrate Volumetric Water Content on Compact Tomato and Pepper Plants by Michael Fidler, Celina Gómez

“…In contrast, shoot height and shoot dry weight of tomato were the only two growth variables affected by VWC, and peppers were mostly unresponsive to differences in VWC. Although plants irrigated with only tap water during production had lower chlorophyll concentrations than those of plants that were fertilized, they quickly greened after receiving a single dose of fertilizer solution, suggesting that using a residual fertilizer strategy before shipping may help increase plant greenness when height-control treatments that induce chlorosis are used. …”
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Digital modeling by biomedical informatics analysis predicts suppression of COVID-19 infectivity via ‘targeting oligonucleotide-directed devolution’ by Frank-Un Hong, Miguel Marciano Castro, Klaus D. Linse

“…The encoding nucleotides exhibited 14 identities, three transitions (C>U or U>C, two; G>A or A>G, one), and 15 transversions (U>A or A>U, eight; C>G or G>C, six; G>U or U>G, one) with mostly complementary base (14/15) for transversion. …”
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