Arteriovenous cerebral high-flow shunts: genetic analysis of patients from a pediatric tertiary care center by Ferruccio Romano, Patrizia De Marco, Giulia Amico, Marisa Mallamaci, Marco Pavanello, Gianluca Piatelli, Marcello Scala, Federico Zara, Federico Zara, Federico Zara, Federico Zara, Federico Zara, Francesca Faravelli, Mariasavina Severino, Mariasavina Severino, Domenico Tortora, Domenico Tortora, Francesco Pasetti, Lucio Castellan, Silvia Buratti, Silvia Buratti, Silvia Buratti, Valeria Capra

“…The clinical phenotypes associated with these conditions are highly variable, with incomplete penetrance and mostly dependent on the hemodynamic consequences (including heart failure and cerebral hemorrhage) or management complications rather than anatomical vascular variations per se. …”
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Dual test gas pulmonary diffusing capacity in patients with idiopathic scoliosis 40 years after diagnosis by Rie S. Thomsen, Milan Mohammad, Lærke C. Ragborg, Casper Dragsted, Søren Ohrt‐Nissen, Martin Gehrchen, Benny Dahl, Ronan M. G. Berg, Jann Mortensen

“…It remains to be determined if impaired pulmonary diffusing capacity is mostly influenced by reduced alveolar–capillary membrane diffusing capacity (DM, CO), reduced pulmonary capillary blood volume (VC) or both. …”
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Factors influencing antibiotic treatment cost and outcome in critically ill patients: A “real-life” study by Perić Aneta, Šurbatović Maja, Vezmar-Kovačević Sandra, Antunović Mirjana, Veljović Milić, Đorđević Dragan, Anđelić Tamara, Zeba Snježana, Dobrić Silva

“…There was a statistically significant difference (p < 0.001) between the sepsis and trauma group regarding outcome (higher mortality rate was in the sepsis group, particularly in the patients with peritonitis who were mostly women). The patients younger than 70 years had better chance of survival. …”
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“Stopping the itch”: mass drug administration for scabies outbreak control covered for over nine million people in Ethiopia by Wendemagegn Enbiale, Tariku Belachew Baynie, Ashenafie Ayalew, Tekilehayimanot Gebrehiwot, Tesfa Getanew, Alie Ayal, Misganaw Ayalew, Henry JC de Vries, Kuda Takarinda, Marcel Manzi, Rony Zachriah

“…Results: The MDA campaign was implemented by about 15,000 people, mostly from the community, over an average of 6 days and reached 9, 057, 427 people. …”
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Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell-Transplantation after Spinal Cord Injury In Vivo by Alexander Younsi, Guoli Zheng, Moritz Scherer, Lennart Riemann, Hao Zhang, Mohamed Tail, Maryam Hatami, Thomas Skutella, Andreas Unterberg, Klaus Zweckberger

“…Eight weeks after SCI, we could observe surviving NPCs in the injured animals that had mostly differentiated into oligodendrocytes and oligodendrocytic precursors. …”
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Immunohistochemistry‐based molecular subtypes of urothelial carcinoma derive different survival benefit from platinum chemotherapy by Csilla Olah, Oleksandr Shmorhun, Gilbert Georg Klamminger, Josefine Rawitzer, Lara Sichward, Boris Hadaschik, Mulham Al‐Nader, Ulrich Krafft, Christian Niedworok, Melinda Váradi, Peter Nyirady, Andras Kiss, Eszter Szekely, Henning Reis, Tibor Szarvas

“…Currently available data were mostly generated at transcriptome level and have limited comparability to each other. …”
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Physical activity and risk of sarcopenia in 6500 community-dwelling Japanese people aged 40–74 years: an 8-year follow-up study by Shoya Wakana, Keiko Kabasawa, Kaori Kitamura, Yumi Watanabe, Tomoyo Komata, Yumi Ito, Akemi Takahashi, Toshiko Saito, Ryosaku Kobayashi, Rieko Oshiki, Ribeka Takachi, Shoichiro Tsugane, Kei Watanabe, Junta Tanaka, Ichiei Narita, Kazutoshi Nakamura

“…Background and aim: The association between physical activity (PA) and sarcopenia has mostly been investigated in older people, with few studies focused on earlier life stages. …”
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Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome by Giovanna Sighinolfi, Giovanni Grandi, Elena Barbieri, Marta Venturelli, Claudia Piombino, Chiara Melotti, Rebecca Lippi Bruni, Riccardo Costantini Cuoghi, Roberto D’Amico, Matteo Lambertini, Fedro A. Peccatori, Elena Tenedini, Massimo Dominici, Laura Cortesi, Antonio La Marca, Angela Toss

“…The significant decrease in AMH levels is mostly ascribable to BRCA1 P/LPV carriers (p = 0.03). …”
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Cytopenias and infections following ciltacabtagene autoleucel in heavily-pretreated relapsed or refractory multiple myeloma by Danai Dima, Jennifer M. Logue, Syed Hamza Bin Waqar, Lauren C. Peres, Christelle M. Colin-Leitzinger, Gabriel De Avila, Eric C. Smith, Lawrence Skelson, Kristy L. Matte, Brandon Blue, Vanna N. Hovanky, Mahmoud Gaballa, Oren Pasvolsky, Laura B. Oswald, Gliceida Galarza M. Fortuna, Charlotte B. Wagner, Shaun DeJarnette, Christen Dillard, Fabiana Perna, Lekha Mikkilineni, Hitomi Hosoya, Ciara L. Freeman, Kenneth H. Shain, Rachid C. Baz, Ariel Grajales-Cruz, Omar Castaneda Puglianini, Melissa Alsina, Frederick L. Locke, Leyla O. Shune, Douglas W. Sborov, Krina K. Patel, Surbhi Sidana, Doris K. Hansen

“…Later infections between days 31-100 and after day 100 were mostly viral (59% and 60%), with only 32% and 12% being grade ≥3 at each time period. …”
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Instruments for assessing patient-reported experience measures among patients with diabetes mellitus: a scoping review by Soe Sandi Tint, Myo Zin Oo, Nida Buawangpong, Wichuda Jiraporncharoen, Nutchar Wiwatkunupakarn, Kittipan Rerkasem, Kanokwan Kulprachakarn, Hataichanok Chuljerm, Timothy E. O’Brien, Rohini Mathur, Chaisiri Angkurawaranon

“…Results Eight articles from six countries representing different healthcare settings were included, mostly from developed countries. A variety of methodologies were used to develop these PREM instruments, with unique domains and items. …”
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Continuous sensing of water status in the root zone of wheat plants reveals features of circadian-dependent water uptake under mild water deficit by Ismael Gutiérrez-Fernández, Ouardia Bendou, Emilio L. Marcos-Barbero, Nara Bueno-Ramos, Ana I. González-Hernández, Rosa Morcuende, Juan B. Arellano

“…Drought studies mostly rely on field capacity (FC) to maintain an imposed soil water deficit. …”
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Enzymatic therapy versus video-assisted thoracoscopic surgery for pleural infections: a systematic review and meta-analysis by Weija R. de Jonge, Bo Smits, Johannes C.F. Ket, Josje Altenburg, Jouke Annema, Johannes M.A. Daniels, Chris Dickhoff, Martijn van Dorp, Jerry Braun, Daniel A. Korevaar, David J. Heineman

“…Results We screened 2263 articles; eight were included in the final analysis, covering 1023 patients (n=465 IET (mostly single agent IET); n=558 VATS). Six were non-randomised studies (n=5 with serious risk of bias) comprising 964 patients, and two were small, randomised feasibility studies (n=1 with high risk of bias), comprising 59 patients. …”
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The Benthic Dinoflagellate <i>Coolia malayensis</i> (Dinophyceae) Produces an Array of Compounds with Antineoplastic Activity in Cells of Tumor Origin by Itzel B. Morales-Montesinos, Maria Yolanda Rios, Yordin D. Ocampo-Acuña, Baldomero Esquivel-Rodríguez, Celia Bustos-Brito, María del Carmen Osorio-Ramírez, Lorena M. Durán-Riveroll, Leticia González-Maya

“…This fraction was identified as mostly fatty acids (FA) by NMR. Seventeen compounds with reported biological activities, such as antioxidant, analgesic, antiviral, and anticancer, were identified from <i>C. malayensis</i> extracts and fractions. …”
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Transitioning a multiethnic donor pool from serologic D-negative to molecularly RHD-negative at a hospital-based blood donor service by Willy A. Flegel, Kshitij Srivastava, Lorraine G. Caruccio, Pirmin Schmid, David A. Stiles, Marina U. Bueno, Nadine R. Dowling, Traci D. Paige, Sita Shrestha

“…Pools of 20 or more donor samples are routinely screened for the RHD gene in some, mostly European, donor populations. Methods A modular real-time PCR assay targeting RHD intron 4, exon 5, and exon 7 was developed for individual testing. …”
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Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1 by Michael L. Davies, Sergei S. Biryukov, Christopher P. Klimko, Jennifer L. Dankmeyer, Nathaniel O. Rill, Melissa Hunter, Christopher T. Braun, Deven W. Patrick, Tyrique D. David, Steven A. Kwilas, Carlos I. Rodriguez, Brian A. Smith, Ju Qiu, Jay W. Hooper, Christopher K. Cote

“…No vaccines for B. pseudomallei have been approved for human use, although several are under development, mostly targeting the antigens Hcp1 (hemolysin-coregulated protein 1) and CPS (capsular polysaccharide). …”
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The morphological, clinical, and prognostic factors in the management of giant anterior communicating artery aneurysms: A systematic review of cases by Roua Nasir, Midhat e Zahra Naqvi, Salaar Ahmed, Maarij ul Hassan, Rabeet Tariq, Saad Akhter Khan, Pia Koeskemeier, Rajiv K. Khajuria, Mohammad Hamza Bajwa, Sajjad Muhammad

“…The mean age was 52 years with an overall male preponderance (3:1). 73% presented with symptoms; mostly visual impairment/loss and subarachnoid hemorrhage. 82% had favorable outcomes (mRS 0–2). 56% had a mean maximum diameter between 25 and 30 mm. …”
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MWA and VLA Observations of Diffuse Radio Lobes in M87 by Linhui Wu, Fu-Guo Xie, Qian Zheng, Quan Guo, Huanyuan Shan, Dan Hu, Stefan W. Duchesne, Nick Seymour, Jingying Wang, Junhua Gu, Qingwen Wu, Zhenghao Zhu, Melanie Johnston-Hollitt, Christopher J. Riseley, Xu-Liang Fan

“…The observed structures feature sharp edges and filaments, with nearly uniform and moderately steep spectral indices ( α , mostly within −1.2 ≤ α ≤ −0.8), indicating turbulence. …”
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Investigating brain network dynamics in state-dependent stimulation: A concurrent electroencephalography and transcranial magnetic stimulation study using hidden Markov models by Saeed Makkinayeri, Roberto Guidotti, Alessio Basti, Mark W. Woolrich, Chetan Gohil, Mauro Pettorruso, Maria Ermolova, Risto J. Ilmoniemi, Ulf Ziemann, Gian Luca Romani, Vittorio Pizzella, Laura Marzetti

“…However, EEG dynamics in these studies are mostly limited to single regions or channels, lacking the spatial resolution needed for accurate network-level characterization. …”
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Evaluating knowledge, practice, and attitude of Syrian population on sexually transmitted infections and human immunodeficiency virus by Sarya Swed, Hidar Alibrahim, Khaled Albakri, Mohammed Amir Rais, Safwan Al-Rassas, Wael Hafez, Bisher Sawaf, Mohammad Badr Almoshantaf, Mohamed Elsayed, Ebraheem Albazee, Huzaifa Ahmad Cheema, Wehba Hraiz, Fatima Taieb, Venus Hussain Ameen, Amine Rakab, Talha Bin Emran, Elrashed AbdElrahim, Hamid Osman, Refat Khan Pathan, Mayeen Uddin Khandaker

“…Results The study involved 1073 participants mostly aged between 18–30, with 55.3% females. Over half had good awareness of STIs and HIV/AIDS, with 55% and 63% respectively. …”
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Prolonged Honeymoon Period in a Thai Patient with Adult-Onset Type 1 Diabetes Mellitus by Yotsapon Thewjitcharoen, Ekgaluck Wanothayaroj, Haruethai Jaita, Soontaree Nakasatien, Siriwan Butadej, Ishant Khurana, Scott Maxwell, Assam El-Osta, Waralee Chatchomchuan, Sirinate Krittiyawong, Thep Himathongkam

“…The “honeymoon” phase among people with type 1 diabetes mellitus (T1DM) refers to the period (mostly less than 1 year) in which beta-cells remain functional and are able to produce insulin to maintain good glycemic control shortly following the development of diabetes. …”
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