Stage-Specific Immune Responses to AgB T-Peptides in Patients with Cystic Echinococcosis by Settimia Sbarra, Ambra Vola, Francesca Tamarozzi, Saeid Najafi-Fard, Alessandra Ludovisi, Antonella Teggi, Emanuele Nicastri, Fabrizio Albarello, Enrico Brunetti, Delia Goletti, Linda Petrone

“…We previously analysed the interleukin (IL)-4 response to T-specific peptides corresponding to the immunogenic regions of the five antigen B (AgB) subunits, demonstrating that AgB1 is the most immunogenic protein and that the response to all AgB peptides is associated with viable cysts. …”
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Diagnostic testing for chronic spontaneous urticaria with or without angioedema: The do's, don't and maybe's by Jonathan A. Bernstein, MD, Ignacio Ansotegui, MD, PhD, Riccardo Asero, MD, Aleena Banerji, MD, Stephen Betschel, HBSc, MD, Timothy Craig, DO, José Luis García-Abujeta, MD, René Maximiliano Gómez, MD, PhD, Anete S. Grumach, MD, PhD, Michihiro Hide, MD, PhD, David M. Lang, MD, Michael Levin, MD, PhD, Hilary J. Longhurst, PhD, Marcus Maurer, MD, Mario Morais-Almeida, MD, Dinh Nguyen Van, MD, PhD, Helena Pité, MD, PhD, Marc A. Riedl, MD, María Isabel Rojo Gutiérrez, MD, Sarbjit S. Saini, MD, Gordon Sussman, MD, Elias Toubi, MD, Andrea Zanichelli, MD, Bruce Zuraw, MD, Torsten Zuberbier, MD, PhD

“…Because acute urticaria will mostly resolve spontaneously, routine testing and laboratory evaluation is not required unless supported by the clinical history or physical examination. …”
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Metabolic status and genetic features of one-carbon metabolism in psoriasis patients during antimetabolite-based therapy by K.V. Misiura, L.V. Roschenyuk, T.V. Tyzhnenko, V.M. Vorontsov, P.P. Ryzhko, N.H. Puzik, T.E. Tkachyk, O.M. Fedota

“…The highest increase (14.50 ± 5.37 mm) in the size of the liver is observed in patients with the CCAA genotype, which is prognostically most favorable for the development of psoriasis and its complications. …”
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THE IMAGE OF A MAN OF CATASTROPHE IN JULIAN BARNES’S NOVEL “THE SENSE OF AN ENDING” by Olena S. Annenkova.

“…Tony’s weak-mindedness and timidity, the desire to be a “non-conflict”» person make him vulnerable to the challenges he faces in the process of growing up and, most importantly, to his first love. For him, Veronica is the Other, in the relationship with whom he can feel his individuality, the value and strength of his originality and its inherent imperfections. …”
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DIAGNOSTICS AND PLANNING OF ORTHODONTIC TREATMENT OF PATIENTS WITH DENTAL ARCH NARROWING USING 3D TECHNOLOGIES by Yu.M. Voliak, Z.R. Ozhohan

“…The study of lateral teleroentgenograms is the most informative way to identify structural features of facial skull. …”
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Effects of generative artificial intelligence (GenAI) patient simulation on perceived clinical competency among global nursing undergraduates: a cross-over randomised controlled tr... by Tai Chun John Fung, Siu Ling Chan, Choi Fung Mabel Lam, Chung Yan Lam, Christopher Chi Wai Cheng, Man Hin Lai, Cheuk Chun Joseph Ho, Siu Lun Au, Lok Yi Mak, Sophia Hu, Supapak Phetrasuwan, Jumpee Granger, Jung Min Yoon, Gulzar Malik, Clara Cabrera Moreno, Man Hei Patrick Kwok, Chia-Chin Lin

“…Both groups experienced changes in CAS scores, though between-group differences were not statistically significant. For SET-M, most participants (75%) felt debriefing contributed to their learning, and 68.2% reported increased confidence in nursing assessment skills. …”
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Human exposure to green spaces and monoterpenes: discovery and use of α-pinene metabolites as biomarkers by Zhengzhi Xie, Saurin R. Sutaria, Jin Y. Chen, Hong Gao, Daniel J. Conklin, Rachel J. Keith, Sanjay Srivastava, Pawel Lorkiewicz, Aruni Bhatnagar

“…A 4 h exposure to a forest environment resulted in significant increases in the most abundant metabolites. This suggests that α-pinene metabolites, specifically myrtenic acid glucuronide and dihydromyrtenic acid glucuronide, may serve as valid biomarkers when assessing individual exposure to green environments. …”
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Penggunaan Cocopeat Sebagai Pengganti Topsoil Dalam Upaya Perbaikan Kualitas Lingkungan di Lahan Pascatambang di Desa Toba, Kabupaten Sanggau by Wafa Shafira, Aji Ali Akbar, Ochih Saziati

“…The composition of the planting medium combination of cocopeat, husk charcoal, and chicken manure has a good effect on the growth of Sengon plants because it has better nutrients than topsoil, without topsoil, or just cocopeat. The most optimal dose of variation in the evolution of Sengon in terms of physical plant growth is the variation in the treatment of planting code D, which has an average plant height increase of 13.7 cm and six-leaf branches, which is more significant than the treatment of other growing media.…”
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Comparing Claims Data to Stroke and Bleeding in the NCDR Left Atrial Appendage Occlusion Registry by Kamil F. Faridi, MD, MSc, James V. Freeman, MD, MPH, MS, Yongfei Wang, MS, Lucy Pereira, BA, Sarah Zimmerman, MS, Daniel J. Friedman, MD, Richa Sharma, MD, MPH, Angela Y. Higgins, MD, Bobak J. Mortazavi, PhD, Joseph S. Ross, MD, MHS, Harlan M. Krumholz, MD, SM, Robert W. Yeh, MD, MSc, MD, MPH, Jeptha P. Curtis, MD

“…Conclusions: In the LAAO Registry, International Classification of Diseases-Tenth Revision codes have moderate agreement with stroke, GIB, and intracranial hemorrhage, and overestimate most event rates compared to adjudicated registry-reported events. …”
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Genetic Diversity and Construction of Salt-Tolerant Core Germplasm in Maize (<i>Zea mays</i> L.) Based on Phenotypic Traits and SNP Markers by Yongfeng Song, Jiahao Wang, Yingwen Ma, Jiaxin Wang, Liangliang Bao, Dequan Sun, Hong Lin, Jinsheng Fan, Yu Zhou, Xing Zeng, Zhenhua Wang, Lin Zhang, Chunxiang Li, Hong Di

“…Nineteen phenotypic traits were evaluated, revealing high genetic diversity and significant correlations among most quantitative traits. The optimal sampling strategy was identified as “Mahalanobis distance + 20% + deviation sampling + flexible method.” …”
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Allelic variants of genes of the main histocompatibility complex in children with type 1 diabetes mellitus who became ill at preschool age by D. N. Laptev, I. A. Eremina, E. S. Shubina, T. E. Yankevich, E. A. Sechko, N. A. Goncharova, V. A. Peterkova

“…In the group with manifestations of DM1 &lt;7 years, there was a high frequency of the most severe predisposing genotype DRB1*03-DQA1*05:01-DQB1*02:01 (DR3-DQ2)/DRB1*04-DQA1*03:01-DQB1*03:02 (DR4-DQ8) (27.5% vs 21.5%, p=0.039]) and a lower frequency of the protective haplotype DRB1*01-DQA1*01-DQB1*05:01 (19.1% vs. 24.9%, p=0.035). …”
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Expression of Astragalus membranaceus phenylalanine ammonia-lyase gene in Pichia pastoris by Zhang Jianhui, Wang Shoufeng

“…Using phenylalanine ammonia-lyase (PAL, EC 4.3.1.5) to produce L-phenylalanine is one of the major routes. However, most commercial enzymes are extracted from Rhodotorula glutinis, which is timeconsuming and over-priced. …”
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Global, regional, and national burden of maternal disorders, 1990–2021: a systematic analysis from the global burden of disease study 2021 by Jie Huang, Yuanyuan Man, Zan Shi, Xiaojie Fu, Wenhao Shi, Xiaoling Liang

“…The Global Burden of Disease Study (GBD), recognized as the most comprehensive epidemiological surveillance system, provides critical evidence for optimizing maternal health policies through systematic quantification of disease burden patterns. …”
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A practical approach to assess the resilience attributes of livestock farms by A. Prat-Benhamou, M.P.M. Meuwissen, T. Slijper, A. Bernués, P. Gaspar-García, J. Lizarralde, J.M. Mancilla-Leytón, N. Mandaluniz, Y. Mena, B. Soriano, D. Martín-Collado

“…Particularly, human capital emerged as one of the most relevant ones across case studies. Farms’ overall resilience scores were significantly lower in the dairy goat system. …”
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Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease by Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng

“…Abstract Alzheimer's disease (AD), the most prevalent type of dementia, is characterized by a biological process that begins with the development of AD neuropathologic change (ADNPC) while individuals remain asymptomatic. …”
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Comparative assessment of efficacy and toxicity of R-DA-EPOCH and R-mNHL-BFM-90 induction courses in the treatment of patients with diffuse large B-cell lymphoma with poor prognost... by M. O. Bagova, A. U. Magomedova, S. K. Kravchenko, Ya. K. Mangasarova, O. V. Margolin, E. S. Nesterova, L. G. Gorenkova, A. E. Misyurina, E. A. Fastova, F. E. Babaeva, K. A. Sychevskaya, S. M. Kulikov, Yu. A. Chabaeva, V. G. Savchenko

“…Diffuse large B-cell lymphoma (DLBCL) is one of the most common and aggressive tumors of the lymphatic system. …”
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L’evolució del pensament escolar al Principat (1808-1845) The evolution of educational thought in Catalonia (1808-1845) La evolución del pensamiento escolar en Catalunya (1808-1845... by Jordi Monés i Pujol-Busquets

“…The paper continues on with a chronological analysis of the most far-reaching political, legal and cultural events, followed by an in-depth analysis of educational thought of this extensive period that the author breaks down into several historical phases: The first absolutist period (1814-1820), the liberal triennium (1820-1823), the second absolutist period (1823-1833), and lastly the triumph of liberalism (1833-1845). …”
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Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability by Wolfgang Sadee, Ian H. Cheeseman, Audrey Papp, Maciej Pietrzak, Michal Seweryn, Xiaofei Zhou, Shili Lin, Amanda M. Williams, Mark D. Wewers, Heather M. Curry, Hao Zhang, Hong Cai, Carine Kunsevi-Kilola, Happy Tshivhula, Gerhard Walzl, Blanca I. Restrepo, Léanie Kleynhans, Katharina Ronacher, Yufeng Wang, Eusondia Arnett, Abul K. Azad, Larry S. Schlesinger

“…While M.tb infection triggers expression changes of numerous host mRNAs, we examined which genes are most variably expressed (VE genes) between donors, as potential biomarkers of individual tuberculosis (TB) risk. …”
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A comparative analysis of hypofractionated versus conventional radiotherapy for cervical cancer in a resource-limited setting: a prospective study by Abba Mallum, Abba Mallum, Abba Mallum, Maureen Bilinga Tendwa, Rakiya Saidu, William Swanson, Paul Phan, Heng Li, Twalib Ngoma, Stephen Avery, M. Saiful Huq, John M. Akudugu, Wilfred Ngwa, Wilfred Ngwa, Luca Incrocci, Mariza Vorster, Mariza Vorster

“…Clinical data and adverse events were recorded and analyzed, with statistical significance set at p &lt; 0.05.ResultsThe median age at diagnosis was 36.4 (28.2–62.9) years, with 85.0% of patients under 40 years and 86.0% HIV-positive. Most patients in both groups presented with stage IIB and grade II disease. …”
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Cancer-associated fibroblast driven paracrine IL-6/STAT3 signaling promotes migration and dissemination in invasive lobular carcinoma by Esme Bullock, Aleksandra Rozyczko, Sana Shabbir, Ifigenia Tsoupi, Adelaide I.J. Young, Jana Travnickova, Laura Gómez-Cuadrado, Zeanap Mabruk, Giovana Carrasco, Elizabeth Morrow, Kathryn Pennel, Pim Kloosterman, Julia M Houthuijzen, Jos Jonkers, Lidia Avalle, Valeria Poli, Richard Iggo, Xue Xiao, Jingjing Guo, Xuan Zhu, Elizabeth Mallon, Joanne Edwards, E. Elizabeth Patton, Valerie G. Brunton

“…Abstract Background Invasive lobular carcinoma (ILC) is the second most common histological subtype of breast cancer after invasive ductal carcinoma of no special type (NST), accounting for 10–15% of diagnoses. …”
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