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95581
Identification and characterization of foehn events in Beijing and their impact on air pollution episodes
Published 2025-08-01“…Analysis of AWS data from 2015 to 2020 revealed an annual average of 56.5 foehn days, with these days occurring most frequently in winter and least frequently in summer. …”
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95582
Comparison of microbial culture, metagenomic next-generation sequencing and droplet digital polymerase chain reaction methods for pathogen detection in patients with neurosurgical...
Published 2025-07-01“…BackgroundNeurosurgical central nervous system infections (NCNSIs) are one of the most common complications in neurosurgical patients, followed by neurosurgery itself, trauma, implants or infection need to be treated by surgery. …”
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95583
Multi-omics elucidates the kidney damage caused by aquatic Cu via the gut-kidney axis in ducks
Published 2025-02-01“…GO and KEGG enrichment analyses were most involved in Interleukin-1 Receptor Activity, Taurine and hypotaurine metabolism, Nitrogen metabolism, and Proximal tubule bicarbonate reclamation. …”
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95584
Splice-site mutation enhances the efficiency of CRISPR-mediated gene knockout and new germplasm creation in fish
Published 2025-09-01“…The CRISPR/cas9 mediated SS mutation was most efficient when the target was selected to produce a DSB within 4 bp flanking the exon-intron boundary. …”
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95585
Directed modification of β-mannanase substrate affinity based on rational design
Published 2014-01-01“…Recently, they have attracted much attention due to their great potential applications in industrial processes, such as bioleaching pulps, depolymerizing ant-i nutritional factors in feedstuffs, extracting oils from leguminous seeds, hydrolyzing mannanbased polymers in hydraulic fracturing of oil and gas wells, and producing mannooligosaccharides. However, most of commercial β-mannanases had some shortages in enzymatic properties, such as lower substrate affinity and poorer tolerance to extreme environments, which hindered the development of β-mannanases.A GH family 5 β-mannanase (AuMan5A) from Aspergillus usamii YL-01-78 was used as the object of this study. …”
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95586
Aspergillusidone G Exerts Anti-Neuroinflammatory Effects via Inhibiting MMP9 Through Integrated Bioinformatics and Experimental Analysis: Implications for Parkinson’s Disease Inter...
Published 2025-04-01“…Further protein–protein interaction analysis indicated that matrix metalloproteinase 9 (MMP9), a promising target for PD intervention, was the most likely anti-PD target of Asp G, and the results of gelatin zymography, qRT-PCR, and Western blot validated that Asp G could inhibit the active and inactive forms of MMP9 directly and indirectly, respectively. …”
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95587
Global burden of cancer attributable to high BMI (1990–2031): a multidimensional analysis based on GBD and Mendelian randomization
Published 2025-08-01“…Finally, projections from the ARIMA model indicate that over the next decade, the ASMR for most cancers attributable to high-BMI will remain stable or increase, except for colon, rectal, and uterine cancers. …”
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95588
Role and Significance of Circulating Biomarkers: miRNA and E2F1 mRNA Expression and Their Association with Type-2 Diabetic Complications
Published 2020-01-01“…In search of novel biomarkers for recording progress of various metabolic diseases, small noncoding RNA in general and microRNAs (miRNAs) in particular have emerged as the most promising biomarkers for diagnosing variety of diseases including diabetes. …”
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95589
Slow virologic control but strong immune and metabolic recovery with dolutegravir-anchored therapy in an HIV cohort in Ghana
Published 2025-07-01“…Common comorbidities were anaemia (54.9%), hepatitis B (9.5%), and hypertension (8.2%). Most participant (97.9%) were on dolutegravir-anchored regimen. …”
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95590
Association between neutrophil-lymphocyte ratio and female breast cancer: an observational study from NHANES 2001-2018 with external validation
Published 2025-07-01“…BackgroundIn the 21st century, breast cancer is the most frequent malignant tumor threatening women’s health. …”
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95591
Later eating timing in relation to an individual internal clock is associated with lower insulin sensitivity and affected by genetic factorsResearch in context
Published 2025-06-01“…Findings: Among components of eating timing, the most associations were found for the circadian time of caloric midpoint (CCM). …”
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95592
Left atrial single-cell transcriptomics reveals amphiregulin as a surrogate marker for atrial fibrillation
Published 2024-12-01“…Amphiregulin (AREG) is the most upregulated gene in monocytes and IL1B+ macrophages in the AF group, compared with healthy controls from other groups. …”
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95593
A survival analysis of dropout among French swimmers
Published 2025-03-01“…Disparities in dropout rates based on birth quarters are most pronounced at 12.7 years for girls (10%) and at 14.7 years for boys (8.1%). …”
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95594
Pre-exposure prophylaxis of COVID-19 with tixagevimab/cilgavimab (Evusheld) in 63 rituximab-treated patients with ANCA-associated systemic vasculitis: two-year follow-up results
Published 2024-11-01“…At the final stage of the study, the serum level of IgG antibodies to SARS-CoV-2 was examined in 34 patients, its median was 70.4 (0.33–1086.1) binding antibody units (BAU), which indicates a lack of neutralizing antibodies in most patients; there were no statistical differences in their level between patients with and without COVID-19 (p=0.685). …”
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95595
Characteristics of grain yield and nitrogen, phosphorus, potassium uptake and accumulation of super hybrid rice grown in different locations
Published 2015-09-01“…Rice is one of the most important staple food crop in China and other Asian countries. …”
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95596
Analysis of the restoration of cardiology diagnostics scope in the Russian Federation during the COVID-19 pandemic: results of the Russian segment of the INCAPS COVID 2 study under...
Published 2022-09-01“…Due to the resumption of patient admissions for cardiac examinations during the ongoing COVID-19 pandemic, with the anti-epidemic measures taken and certain changes in the workflow, there has been a recovery in the diagnostics scope in most of the included centers.…”
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95597
Diagnosis of Columnar Metaplasia of the Esophageal Mucosa in Patients with Complicated Gastroesophageal Reflux Disease
Published 2024-03-01“…Targeted forceps biopsy was performed from the altered areas that most quickly lost their coloring. The final stage of the diagnostic program in all patients was a forceps biopsy of the mucosa of the metaplasic segment according to the Seattle protocol, which requires increasing the number of fragments as the metaplasic segment lengthens in a “blind” biopsy. …”
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95598
Concepções de saúde e educação em saúde: um estudo com professores do ensino fundamental [Conceptions of health and health education: a study of primary and lower secondary teacher...
Published 2017-12-01“…Results: health figured as strongly related to physical activity, nutrition and well-being. Most teachers did not relate health to their disciplines, and when they did so, it was informal and unplanned. …”
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95599
Evolution analysis of sweet osmanthus (Osmanthus fragrans) cultivars based on sequence-related amplified polymorphism molecular marker
Published 2017-07-01“…O. fragrans Asiaticus Group was considered as the most primitive cultivars, and the ones with light color flowers formed earlier, then followed by deep color flowers. …”
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95600
Reconstructing central African hydroclimate over the past century using freshwater bivalve shell geochemistry
Published 2025-06-01“…Thus, while the freshwater shell <span class="inline-formula"><i>δ</i><sup>18</sup>O</span> patterns are consistent with the documented long-term <span class="inline-formula"><i>Q</i></span> changes in the Oubangui, the shells show that the most pronounced changes in hydroclimate over the past century are expressed in low-flow sections of the hydrograph and likely result from a combination of changes in the rainfall regime, aquifer recharge, and/or vegetation cover in the upper catchment. …”
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